| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Blum, G Wu, G Mudó, N Belluardo, K Andersson, L F Agnati, K Fux. Chronic continuous infusion of (-)nicotine reduces basic fibroblast growth factor messenger RNA levels in the ventral midbrain of the intact but not of the 6-hydroxydopamine-lesioned rat. Neuroscience. vol 70. issue 1. 1996-10-24. PMID:8848122. |
therefore, it is of interest to explore a possible effect of nicotine on basic fibroblast growth factor expression in the ventral midbrain of intact and 6-hydroxydopamine-lesioned rats and how treatment with nicotine can alter the 6-hydroxydopamine-induced injury of the nigral dopamine nerve cells as evaluated by dopamine biochemistry. |
1996-10-24 |
2023-08-12 |
rat |
| W Pirker, S Asenbaum, S Kasper, H Walter, P Angelberger, G Koch, A Pozzera, L Deecke, I Podreka, T Brück. beta-CIT SPECT demonstrates blockade of 5HT-uptake sites by citalopram in the human brain in vivo. Journal of neural transmission. General section. vol 100. issue 3. 1996-10-23. PMID:8748670. |
it was demonstrated previously by spect-studies in non-human primates that 123i-beta-cit binds to dopamine transporters in the striatum and to serotonin transporters in hypothalamus and midbrain. |
1996-10-23 |
2023-08-12 |
human |
| K Rasmussen, J F Czachur. Nicotine withdrawal leads to increased firing rates of midbrain dopamine neurons. Neuroreport. vol 7. issue 1. 1996-10-17. PMID:8742482. |
nicotine withdrawal leads to increased firing rates of midbrain dopamine neurons. |
1996-10-17 |
2023-08-12 |
rat |
| D J Healy, J H Meador-Woodruf. Differential regulation, by MK-801, of dopamine receptor gene expression in rat nigrostriatal and mesocorticolimbic systems. Brain research. vol 708. issue 1-2. 1996-10-11. PMID:8720857. |
dopamine autoreceptor expression, reflected by d2 mrna in the midbrain, was increased in the ventral tegmental area, but not in the substantia nigra. |
1996-10-11 |
2023-08-12 |
rat |
| M S Star. The role of dopamine in epilepsy. Synapse (New York, N.Y.). vol 22. issue 2. 1996-09-26. PMID:8787131. |
the traditional anticonvulsant action of dopamine was attributed to d2 receptor stimulation in the forebrain, while the advent of selective d1 agonists with proconvulsant properties revealed for the first time that dopamine could also lower the seizure threshold from the midbrain. |
1996-09-26 |
2023-08-12 |
Not clear |
| M Tanaka, Y Matsumoto, T Murakami, Y Hisa, Y Ibat. The origins of catecholaminergic innervation in the rostral ventromedial medulla oblongata of the rat. Neuroscience letters. vol 207. issue 1. 1996-09-09. PMID:8710209. |
no dopamine neurons in the midbrain and forebrain were double-labeled with th and fluospheres. |
1996-09-09 |
2023-08-12 |
rat |
| J Zhang, L Wang, D K Pitt. Prenatal haloperidol reduces the number of active midbrain dopamine neurons in rat offspring. Neurotoxicology and teratology. vol 18. issue 1. 1996-09-03. PMID:8700043. |
prenatal haloperidol reduces the number of active midbrain dopamine neurons in rat offspring. |
1996-09-03 |
2023-08-12 |
rat |
| J Zhang, L Wang, D K Pitt. Prenatal haloperidol reduces the number of active midbrain dopamine neurons in rat offspring. Neurotoxicology and teratology. vol 18. issue 1. 1996-09-03. PMID:8700043. |
in extracellular electrophysiological studies, the male 2-week-old offspring from all hal treatment groups were found to have significantly reduced average numbers of spontaneously active midbrain dopamine (da)-containing neurons in both the substantia nigra (a9) and the ventral tegmental area (a10) relative to controls. |
1996-09-03 |
2023-08-12 |
rat |
| J D Elsworth, M S Brittan, J R Taylor, J R Sladek, M S al-Tikriti, Y Zea-Ponce, R B Innis, D E Redmond, R H Rot. Restoration of dopamine transporter density in the striatum of fetal ventral mesencephalon-grafted, but not sham-grafted, MPTP-treated parkinsonian monkeys. Cell transplantation. vol 5. issue 2. 1996-08-27. PMID:8689042. |
each grafted mptp-treated monkey received ventral mesencephalon dopamine neurons from one donor harvested during putative neurogenesis. |
1996-08-27 |
2023-08-12 |
human |
| C N Svendsen, D J Clarke, A E Rosser, S B Dunnet. Survival and differentiation of rat and human epidermal growth factor-responsive precursor cells following grafting into the lesioned adult central nervous system. Experimental neurology. vol 137. issue 2. 1996-07-11. PMID:8635554. |
in this study we have shown that purified rat stem cells generated from either the embryonic mesencephalon or the striatum can survive grafting into the striatum of rats with either ibotenic acid or nigrostriatal dopamine lesions. |
1996-07-11 |
2023-08-12 |
human |
| C N Svendsen, D J Clarke, A E Rosser, S B Dunnet. Survival and differentiation of rat and human epidermal growth factor-responsive precursor cells following grafting into the lesioned adult central nervous system. Experimental neurology. vol 137. issue 2. 1996-07-11. PMID:8635554. |
some of these appeared to differentiate into dopamine neurons, particularly when the developing mesencephalon was used as the starting material for generating the stem cells. |
1996-07-11 |
2023-08-12 |
human |
| D M Gash, Z Zhang, A Ovadia, W A Cass, A Yi, L Simmerman, D Russell, D Martin, P A Lapchak, F Collins, B J Hoffer, G A Gerhard. Functional recovery in parkinsonian monkeys treated with GDNF. Nature. vol 380. issue 6571. 1996-07-05. PMID:8637574. |
in rodents, glial-cell-line-derived neurotrophic factor (gdnf) stimulates an increase in midbrain dopamine levels, protects dopamine neurons from some neurotoxins, and maintains injured dopamine neurons. |
1996-07-05 |
2023-08-12 |
human |
| D M Gash, Z Zhang, A Ovadia, W A Cass, A Yi, L Simmerman, D Russell, D Martin, P A Lapchak, F Collins, B J Hoffer, G A Gerhard. Functional recovery in parkinsonian monkeys treated with GDNF. Nature. vol 380. issue 6571. 1996-07-05. PMID:8637574. |
on the lesioned side of gdnf-treated animals, dopamine levels in the midbrain and globus pallidus were twice as high, and nigral dopamine neurons were, on average, 20% larger, with an increased fibre density. |
1996-07-05 |
2023-08-12 |
human |
| D Sulzer, C St Remy, S Raypor. Reserpine inhibits amphetamine action in ventral midbrain culture. Molecular pharmacology. vol 49. issue 2. 1996-07-03. PMID:8632767. |
to address this paradox, we examined the effect of reserpine on amphetamine-induced dopamine release from postnatal ventral midbrain neurons in culture. |
1996-07-03 |
2023-08-12 |
Not clear |
| N H Chen, C Xu, L L Coffey, M E Reit. [3H]WIN 35,428 [2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane] binding to rat brain membranes. Comparing dopamine cell body areas with nerve terminal regions. Biochemical pharmacology. vol 51. issue 4. 1996-06-13. PMID:8619903. |
potential differences between somatodendritic acid and axonal dopamine transporters were examined by comparing the binding constants of [3h]win 35, 428 [2 beta-carbomethoxy- 3 beta-(4-fluorophenyl)tropane] binding to membranes prepared from the rat ventral mesencephalon, containing a9 and a10 dopamine cell bodies, and from the nucleus accumbens. |
1996-06-13 |
2023-08-12 |
rat |
| N H Chen, C Xu, L L Coffey, M E Reit. [3H]WIN 35,428 [2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane] binding to rat brain membranes. Comparing dopamine cell body areas with nerve terminal regions. Biochemical pharmacology. vol 51. issue 4. 1996-06-13. PMID:8619903. |
the results suggest that somatodendritic and axonal dopamine transporters in the ventral mesencephalon and nucleus accumbens are not very different as far as their binding domains for uptake blockers such as cocaine and gbr 12909 are concerned. |
1996-06-13 |
2023-08-12 |
rat |
| S M Waters, C S Konkoy, T P Davi. Haloperidol and apomorphine differentially affect neuropeptidase activity. The Journal of pharmacology and experimental therapeutics. vol 277. issue 1. 1996-06-06. PMID:8613907. |
in view of the interaction between mesocorticolimbic dopamine neurons and neuropeptides, e.g., substance p, neurotensin and enkephalins, neuroleptic-induced alterations in the activities of neuropeptidases, and thus neuropeptide metabolism can, in turn, play a role in modulating midbrain dopaminergic activity. |
1996-06-06 |
2023-08-12 |
rat |
| Y Minabe, K Emori, C R Ashb. Significant differences in the activity of midbrain dopamine neurons between male Fischer 344 (F344) and Lewis rats: an in vivo electrophysiological study. Life sciences. vol 56. issue 15. 1996-06-03. PMID:8614235. |
significant differences in the activity of midbrain dopamine neurons between male fischer 344 (f344) and lewis rats: an in vivo electrophysiological study. |
1996-06-03 |
2023-08-12 |
rat |
| G Alonso, O Brun, J L Ridet, M Geffard, N Chauve. Non-dopaminergic catecholaminergic neurons of mesencephalic and medullary nuclei contain different levels of dopamine. Journal of chemical neuroanatomy. vol 9. issue 3. 1996-03-22. PMID:8588834. |
these data indicate that two types of non-dopaminergic catecholaminergic neurons can be distinguished according to their content in dopamine: (i) the noradrenergic and adrenergic neurons located in the medulla oblongata, whose cell bodies and axons contain high concentrations of metabolic dopamine and (ii) the noradrenergic neurons located in the mesencephalon, which contain low levels of metabolic dopamine. |
1996-03-22 |
2023-08-12 |
Not clear |
| R Arai, N Karasawa, M Geffard, I Nagats. L-DOPA is converted to dopamine in serotonergic fibers of the striatum of the rat: a double-labeling immunofluorescence study. Neuroscience letters. vol 195. issue 3. 1996-03-21. PMID:8584208. |
in rats that received intraperitoneally l-dopa plus a peripheral decarboxylase inhibitor, we showed by use of a double-labeling immunofluorescence method that dopamine was localized in serotonergic fibers of the striatum and cerebral cortex as well as in serotonergic cell bodies of the midbrain raphe nuclei. |
1996-03-21 |
2023-08-12 |
rat |