| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anthony D Miller, Charles D Blah. Midbrain muscarinic receptor mechanisms underlying regulation of mesoaccumbens and nigrostriatal dopaminergic transmission in the rat. The European journal of neuroscience. vol 21. issue 7. 2005-07-05. PMID:15869479. |
the present study investigated the role of midbrain muscarinic receptors in the functional modulation of vta and snc dopamine cell activity as reflected by alterations in, respectively, nucleus accumbens (nac) and striataldopamine efflux. |
2005-07-05 |
2023-08-12 |
rat |
| Anthony D Miller, Charles D Blah. Midbrain muscarinic receptor mechanisms underlying regulation of mesoaccumbens and nigrostriatal dopaminergic transmission in the rat. The European journal of neuroscience. vol 21. issue 7. 2005-07-05. PMID:15869479. |
together, these findings suggest that midbrain muscarinic receptors, probably m5 subtypes on vta and snc dopamine neurons, contribute to the tonic excitatory regulation of forebrain basal dopamine transmission whereas presynaptic m3 receptors serve to counter excessive excitation of nigral dopamine cell activity. |
2005-07-05 |
2023-08-12 |
rat |
| Justyna Pawlak, Magdalena Karolczak, Andre Krust, P Chambon, Cordian Beye. Estrogen receptor-alpha is associated with the plasma membrane of astrocytes and coupled to the MAP/Src-kinase pathway. Glia. vol 50. issue 3. 2005-06-30. PMID:15712205. |
the physiological consequence of this phenomenon is not yet understood, but it might have a pivotal role in estrogen-mediated protective effects on midbrain dopamine neurons. |
2005-06-30 |
2023-08-12 |
Not clear |
| Matthew Maingay, Marina Romero-Ramos, Deniz Kiri. Viral vector mediated overexpression of human alpha-synuclein in the nigrostriatal dopaminergic neurons: a new model for Parkinson's disease. CNS spectrums. vol 10. issue 3. 2005-06-24. PMID:15744224. |
parkinson's disease is predominantly a dopamine deficiency syndrome, which is produced in the brain by the loss of cells located in a small area in the ventral midbrain called the substantia nigra. |
2005-06-24 |
2023-08-12 |
human |
| François J Michel, Gabriel D Fortin, Philippe Martel, John Yeomans, Louis-Eric Trudea. M3-like muscarinic receptors mediate Ca2+ influx in rat mesencephalic GABAergic neurones through a protein kinase C-dependent mechanism. Neuropharmacology. vol 48. issue 6. 2005-06-24. PMID:15829252. |
gabaergic neurones in the mesencephalon are important regulators of dopamine neurones. |
2005-06-24 |
2023-08-12 |
rat |
| Gonçalo Castelo-Branco, Nina Rawal, Ernest Arena. GSK-3beta inhibition/beta-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons. Journal of cell science. vol 117. issue Pt 24. 2005-06-20. PMID:15522889. |
gsk-3beta inhibition/beta-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons. |
2005-06-20 |
2023-08-12 |
Not clear |
| Gonçalo Castelo-Branco, Nina Rawal, Ernest Arena. GSK-3beta inhibition/beta-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons. Journal of cell science. vol 117. issue Pt 24. 2005-06-20. PMID:15522889. |
wnts are important regulators of dopamine (da) neuron differentiation in the developing ventral mesencephalon and could thus serve as potential tools in the treatment of parkinson's disease. |
2005-06-20 |
2023-08-12 |
Not clear |
| M V Pivovarchi. [Change of dopamine, serotonin and opioid neuromediator systems in the brain of rats adapted to prolonged effect of ethanol]. Ukrains'kyi biokhimichnyi zhurnal (1999 ). vol 76. issue 2. 2005-06-17. PMID:15915718. |
to investigate the effect of in vivo short-term ethanol administration (i.p., 1.5 g/kg, 6 h) on binding characteristics of opioid receptor agonists in rat midbrain, as well as the contents of dopamine, serotonin and their precursors and metabolites in midbrain, striatum and hypothalamus of rats after long-term alcohol consumption. |
2005-06-17 |
2023-08-12 |
rat |
| Nikolaos Patsoukis, Ioannis Papapostolou, George Zervoudakis, Christos D Georgiou, Nikolaos A Matsokis, Nikolaos T Panagopoulo. Thiol redox state and oxidative stress in midbrain and striatum of weaver mutant mice, a genetic model of nigrostriatal dopamine deficiency. Neuroscience letters. vol 376. issue 1. 2005-06-14. PMID:15694268. |
thiol redox state and oxidative stress in midbrain and striatum of weaver mutant mice, a genetic model of nigrostriatal dopamine deficiency. |
2005-06-14 |
2023-08-12 |
mouse |
| Nikolaos Patsoukis, Ioannis Papapostolou, George Zervoudakis, Christos D Georgiou, Nikolaos A Matsokis, Nikolaos T Panagopoulo. Thiol redox state and oxidative stress in midbrain and striatum of weaver mutant mice, a genetic model of nigrostriatal dopamine deficiency. Neuroscience letters. vol 376. issue 1. 2005-06-14. PMID:15694268. |
in the striatum of male wv/wv, protein and non-protein thiol/disulfide and mda levels do not change, possibly due to the high decrease in striatal dopamine level versus midbrain. |
2005-06-14 |
2023-08-12 |
mouse |
| Alfred Heller, Lisa Won, Nancy Bubula, Suzanne Hessefort, Josh W Kurutz, Giridher A Reddy, Martin Gros. Long-chain fatty acids increase cellular dopamine in an immortalized cell line (MN9D) derived from mouse mesencephalon. Neuroscience letters. vol 376. issue 1. 2005-06-14. PMID:15694270. |
long-chain fatty acids increase cellular dopamine in an immortalized cell line (mn9d) derived from mouse mesencephalon. |
2005-06-14 |
2023-08-12 |
mouse |
| Fayi Yao, Fei Yu, Lijie Gong, David Taube, Donald D Rao, Robert G MacKenzi. Microarray analysis of fluoro-gold labeled rat dopamine neurons harvested by laser capture microdissection. Journal of neuroscience methods. vol 143. issue 2. 2005-06-07. PMID:15814141. |
the present study employed a fluorescent neural tracer to specifically label midbrain dopamine neurons and non-dopamine cortical neurons. |
2005-06-07 |
2023-08-12 |
rat |
| P B Osborne, G M Halliday, H M Cooper, J R Keas. Localization of immunoreactivity for deleted in colorectal cancer (DCC), the receptor for the guidance factor netrin-1, in ventral tier dopamine projection pathways in adult rodents. Neuroscience. vol 131. issue 3. 2005-06-06. PMID:15730872. |
significant dcc-immunoreactivity was detected in midbrain, where it was localized to ventrally displaced a9 dopamine neurons in the substantia nigra, and ventromedial a10 dopamine neurons predominantly situated in and around the interfascicular nucleus. |
2005-06-06 |
2023-08-12 |
Not clear |
| P B Osborne, G M Halliday, H M Cooper, J R Keas. Localization of immunoreactivity for deleted in colorectal cancer (DCC), the receptor for the guidance factor netrin-1, in ventral tier dopamine projection pathways in adult rodents. Neuroscience. vol 131. issue 3. 2005-06-06. PMID:15730872. |
strong immunoreactivity was not detected in dopamine neurons found elsewhere, or in non-dopamine-containing neurons in the midbrain. |
2005-06-06 |
2023-08-12 |
Not clear |
| P B Osborne, G M Halliday, H M Cooper, J R Keas. Localization of immunoreactivity for deleted in colorectal cancer (DCC), the receptor for the guidance factor netrin-1, in ventral tier dopamine projection pathways in adult rodents. Neuroscience. vol 131. issue 3. 2005-06-06. PMID:15730872. |
the unique distribution of dcc-immunoreactivity in adult ventral midbrain dopamine neurons suggests that netrin-1/dcc signaling could function in plasticity and remodeling previously identified in dopamine projection pathways. |
2005-06-06 |
2023-08-12 |
Not clear |
| Ji-Yun Ko, Ji-Yeon Lee, Chang-Hwan Park, Sang-Hun Le. Effect of cell-density on in-vitro dopaminergic differentiation of mesencephalic precursor cells. Neuroreport. vol 16. issue 5. 2005-06-06. PMID:15770159. |
neural precursor cells isolated from early embryonic mesencephalon are in-vitro expanded and differentiated toward dopamine neurons. |
2005-06-06 |
2023-08-12 |
Not clear |
| G Chadi, V C Gomid. FGF-2 and S100beta immunoreactivities increase in reactive astrocytes, but not in microglia, in ascending dopamine pathways following a striatal 6-OHDA-induced partial lesion of the nigrostriatal system. Cell biology international. vol 28. issue 12. 2005-05-31. PMID:15566955. |
partial lesions were induced in rat midbrain dopamine ascending pathways by intrastriatal injection of 6-hydroxydopamine (6-ohda), and after two weeks changes were observed in the immunoreactivities of s100beta, a calcium-binding protein, and basic fibroblast growth factor (fgf-2), which is neurotrophic. |
2005-05-31 |
2023-08-12 |
rat |
| G Chadi, V C Gomid. FGF-2 and S100beta immunoreactivities increase in reactive astrocytes, but not in microglia, in ascending dopamine pathways following a striatal 6-OHDA-induced partial lesion of the nigrostriatal system. Cell biology international. vol 28. issue 12. 2005-05-31. PMID:15566955. |
these results indicate that reactive astrocytes may exert paracrine trophic actions through s100beta and fgf-2 in the midbrain dopamine ascending pathways after striatal 6-ohda treatment. |
2005-05-31 |
2023-08-12 |
rat |
| Andrew Sharott, Peter J Magill, Daniel Harnack, Andreas Kupsch, Wassilios Meissner, Peter Brow. Dopamine depletion increases the power and coherence of beta-oscillations in the cerebral cortex and subthalamic nucleus of the awake rat. The European journal of neuroscience. vol 21. issue 5. 2005-05-27. PMID:15813951. |
here we show that 6-hydroxydopamine (6-ohda) lesions of midbrain dopamine neurons are associated with significant increases in the power and coherence of beta-frequency oscillatory activity present in lfps recorded from frontal cortex and stn of awake rats, as compared with the healthy animal. |
2005-05-27 |
2023-08-12 |
human |
| Shin Hye Kim, Yu Mi Choi, Sungkwon Chung, Dae Yong Uhm, Myoung Kyu Par. Two different Ca2+-dependent inhibitory mechanisms of spontaneous firing by glutamate in dopamine neurons. Journal of neurochemistry. vol 91. issue 4. 2005-05-25. PMID:15525352. |
the excitatory neurotransmitter, glutamate, generates a characteristic burst-pause type of firing in midbrain dopamine neurons in association with the reward behavior, but the cellular mechanism by which glutamate generates these bursts is unknown. |
2005-05-25 |
2023-08-12 |
Not clear |