| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ming Lei, Lu Luo, Shi-Qi Ma, Yan Zhang, Xi-Hong Wu, Liang L. [Behavioral and neurobiological abnormalities induced by social isolation as a useful animal model of schizophrenia]. Sheng li xue bao : [Acta physiologica Sinica]. vol 65. issue 1. 2015-05-16. PMID:23426521. |
moreover, social isolation causes changes of neurotransmitters, such as the increase of dopamine in the nucleus accumbens, the amygdala and other brain regions in the limbic system, the decrease of dopamine in medial prefrontal cortex, the decrease of 5-ht in the nucleus accumbens and the hippocampus, and changes of glutamine in the prefrontal cortex. |
2015-05-16 |
2023-08-12 |
rat |
| S Samaddar, B Ranasinghe, S J Tantry, P R Debata, P Banerje. Involvement of vascular endothelial growth factor in serotonin 1A receptor-mediated neuroproliferation in neonatal mouse hippocampus. Advances in experimental medicine and biology. vol 842. 2015-05-01. PMID:25408355. |
involvement of vascular endothelial growth factor in serotonin 1a receptor-mediated neuroproliferation in neonatal mouse hippocampus. |
2015-05-01 |
2023-08-13 |
mouse |
| Lisa M McFadden, Paula L Vieira-Brock, Glen R Hanson, Annette E Fleckenstei. Methamphetamine self-administration attenuates hippocampal serotonergic deficits: role of brain-derived neurotrophic factor. The international journal of neuropsychopharmacology. vol 17. issue 8. 2015-04-14. PMID:24650575. |
preclinical studies suggest that prior treatment with escalating doses of methamphetamine (meth) attenuates the persistent deficits in hippocampal serotonin (5-hydroxytryptamine; 5ht) transporter (sert) function resulting from a subsequent 'binge' meth exposure. |
2015-04-14 |
2023-08-12 |
rat |
| Anna Min, Fengming Liu, Xu Yang, Mingqing Che. Benzyl butyl phthalate exposure impairs learning and memory and attenuates neurotransmission and CREB phosphorylation in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 71. 2015-04-06. PMID:24937021. |
the modified levels of 5-ht in the hippocampus and the decreased levels of creb phosphorylation after bbp exposure suggested a potential mechanism underlying bbp toxicity. |
2015-04-06 |
2023-08-13 |
mouse |
| Takayoshi Mamiya, Yuya Hasegawa, Masayuki Hiramats. Dynorphin a (1-13) alleviated stress-induced behavioral impairments in mice. Biological & pharmaceutical bulletin. vol 37. issue 8. 2015-04-06. PMID:25087948. |
however, there were no differences in 5-ht or 5-hiaa content or their ratios in the hippocampus among the three groups. |
2015-04-06 |
2023-08-13 |
mouse |
| Tae-Woon Kim, Eun-Sang Ji, Tae-Wook Kim, Sang-Won Lee, Choong-Yeol Lee, Sam-Jun Le. Postnatal treadmill exercise attenuates prenatal stress-induced apoptosis through enhancing serotonin expression in aged-offspring rats. Journal of exercise rehabilitation. vol 11. issue 1. 2015-04-01. PMID:25830139. |
in the present results, offspring exposed to prenatal stress exhibited lower bcl-2 level and higher bax level in the hippocampus, lower 5-hydroxytryptamine (5-ht) and tryptophan hydroxylase (tph) expression in the dorsal raphe, and higher c-fos expression in the locus coeruleus compared to age-matched control rats. |
2015-04-01 |
2023-08-13 |
rat |
| Tae-Woon Kim, Eun-Sang Ji, Tae-Wook Kim, Sang-Won Lee, Choong-Yeol Lee, Sam-Jun Le. Postnatal treadmill exercise attenuates prenatal stress-induced apoptosis through enhancing serotonin expression in aged-offspring rats. Journal of exercise rehabilitation. vol 11. issue 1. 2015-04-01. PMID:25830139. |
treadmill exercise of offspring suppressed bax expression and enhanced bcl-2 expression in the hippocampus, increased 5-ht and tph expression in the dorsal raphe, and enhanced c-fos expression in the locus coeruleus of offspring. |
2015-04-01 |
2023-08-13 |
rat |
| Ying Xin Wang, Xiang Rong Zhang, Zhi Jun Zhang, Lei Li, Guang Jun Xi, Di Wu, Yan Juan Wan. Protein kinase Mζ is involved in the modulatory effect of fluoxetine on hippocampal neurogenesis in vitro. The international journal of neuropsychopharmacology. vol 17. issue 9. 2015-03-30. PMID:24679950. |
the efficacy of chronic selective serotonin reuptake inhibitors (ssris) on depression is paralleled by the recovery of deficits in hippocampal neurogenesis related to sustained stress and elevated glucocorticoids. |
2015-03-30 |
2023-08-12 |
rat |
| Lara Costa, Lara M Sardone, Enza Lacivita, Marcello Leopoldo, Lucia Cirann. Novel agonists for serotonin 5-HT7 receptors reverse metabotropic glutamate receptor-mediated long-term depression in the hippocampus of wild-type and Fmr1 KO mice, a model of Fragile X Syndrome. Frontiers in behavioral neuroscience. vol 9. 2015-03-27. PMID:25814945. |
novel agonists for serotonin 5-ht7 receptors reverse metabotropic glutamate receptor-mediated long-term depression in the hippocampus of wild-type and fmr1 ko mice, a model of fragile x syndrome. |
2015-03-27 |
2023-08-13 |
mouse |
| Lara Costa, Lara M Sardone, Enza Lacivita, Marcello Leopoldo, Lucia Cirann. Novel agonists for serotonin 5-HT7 receptors reverse metabotropic glutamate receptor-mediated long-term depression in the hippocampus of wild-type and Fmr1 KO mice, a model of Fragile X Syndrome. Frontiers in behavioral neuroscience. vol 9. 2015-03-27. PMID:25814945. |
serotonin 5-ht7 receptors are expressed in the hippocampus and modulate the excitability of hippocampal neurons. |
2015-03-27 |
2023-08-13 |
mouse |
| Shuang Yu, Ling Chen, Xing-hui Cai, Xiao-ge Song, Yue Zhang, Yang Zhang, Rui Song, Yi-fang L. [Effect of manual acupuncture stimulation of "Baihui" (GV 20) and "Dazhui" (GV 14) on contents of 5-HT, dopamine and ACh and expression of 5-HT mRNA, DA mRNA and AChE mRNA in the hippocampus in methamphetamine addiction rats]. Zhen ci yan jiu = Acupuncture research. vol 39. issue 5. 2015-03-12. PMID:25518108. |
[effect of manual acupuncture stimulation of "baihui" (gv 20) and "dazhui" (gv 14) on contents of 5-ht, dopamine and ach and expression of 5-ht mrna, da mrna and ache mrna in the hippocampus in methamphetamine addiction rats]. |
2015-03-12 |
2023-08-13 |
rat |
| Shuang Yu, Ling Chen, Xing-hui Cai, Xiao-ge Song, Yue Zhang, Yang Zhang, Rui Song, Yi-fang L. [Effect of manual acupuncture stimulation of "Baihui" (GV 20) and "Dazhui" (GV 14) on contents of 5-HT, dopamine and ACh and expression of 5-HT mRNA, DA mRNA and AChE mRNA in the hippocampus in methamphetamine addiction rats]. Zhen ci yan jiu = Acupuncture research. vol 39. issue 5. 2015-03-12. PMID:25518108. |
to observe the effect of manual acupuncture stimulation on changes of hippocampal monoamine neurotransmitter levels and expression of 5-hydorxytryptamine (5-ht) mrna, dopamine (da) mrna and acetylcholine esterase (ache) mrna in methamphetamine addiction rats, so as to explore its mechanism underlying improvement of drug addiction. |
2015-03-12 |
2023-08-13 |
rat |
| Ping Yang, Meizhen Sun, Liang Li, Yihua She. 8-hydroxy-dipropylaminotetralin promotes neural plasticity in epileptic rats with depression. Neural regeneration research. vol 7. issue 8. 2015-03-06. PMID:25745445. |
neurogenesis within the hippocampal dentate gyrus was further enhanced, while mossy fiber sprouting was decreased in model rats administered carbamazepine alone or in combination with the 5-hydroxytryptamine 1a receptor agonist, 8-hydroxy-dipropylaminotetralin (0.1 and 1 mg/kg). |
2015-03-06 |
2023-08-13 |
rat |
| Judith Regina Homberg, Raffaella Molteni, Francesca Calabrese, Marco A Riv. The serotonin-BDNF duo: developmental implications for the vulnerability to psychopathology. Neuroscience and biobehavioral reviews. vol 43. 2015-02-27. PMID:24704572. |
5-htt knockout in rats, as well as the low activity short allelic variant of the serotonin transporter human polymorphism, consistently show reduced bdnf mrna and protein levels in the hippocampus and in the prefrontal cortex. |
2015-02-27 |
2023-08-13 |
human |
| Manal F El-Khadragy, Ebtesam M Al-Olayan, Ahmed E Abdel Monei. Neuroprotective effects of Citrus reticulata in scopolamine-induced dementia oxidative stress in rats. CNS & neurological disorders drug targets. vol 13. issue 4. 2015-02-23. PMID:24938777. |
this study also investigated the effect of scopolamine on norepinephrine, dopamine and serotonin content in rat hippocampus, striatum and cerebral cortex. |
2015-02-23 |
2023-08-13 |
rat |
| Vladimir S Naumenko, Elena M Kondaurova, Daria V Bazovkina, Anton S Tsybko, Tatyana V Il'chibaeva, Nina K Popov. On the role of 5-HT(1A) receptor gene in behavioral effect of brain-derived neurotrophic factor. Journal of neuroscience research. vol 92. issue 8. 2015-02-21. PMID:24706292. |
functional activity of 5-ht2a receptors and 5-ht(2a) receptor mrna levels in the midbrain and hippocampus of 76c mice were decreased compared with akr mice. |
2015-02-21 |
2023-08-13 |
mouse |
| Paulina S Rojas, David Neira, Mauricio Muñoz, Sergio Lavandero, Jenny L Fiedle. Serotonin (5-HT) regulates neurite outgrowth through 5-HT1A and 5-HT7 receptors in cultured hippocampal neurons. Journal of neuroscience research. vol 92. issue 8. 2015-02-21. PMID:24752854. |
serotonin (5-ht) regulates neurite outgrowth through 5-ht1a and 5-ht7 receptors in cultured hippocampal neurons. |
2015-02-21 |
2023-08-13 |
rat |
| Paulina S Rojas, David Neira, Mauricio Muñoz, Sergio Lavandero, Jenny L Fiedle. Serotonin (5-HT) regulates neurite outgrowth through 5-HT1A and 5-HT7 receptors in cultured hippocampal neurons. Journal of neuroscience research. vol 92. issue 8. 2015-02-21. PMID:24752854. |
thus, we hypothesized that 5-ht promotes neurite outgrowth through 5-ht1a r and 5-ht7 r. the involvement of 5-ht1a r and 5-ht7 r in the morphology of rat hippocampal neurons was evaluated by treating primary cultures at 2 days in vitro with 5-ht and specific antagonists for 5-ht1a r and 5-ht7 r (way-100635 and sb269970, respectively). |
2015-02-21 |
2023-08-13 |
rat |
| Paulina S Rojas, David Neira, Mauricio Muñoz, Sergio Lavandero, Jenny L Fiedle. Serotonin (5-HT) regulates neurite outgrowth through 5-HT1A and 5-HT7 receptors in cultured hippocampal neurons. Journal of neuroscience research. vol 92. issue 8. 2015-02-21. PMID:24752854. |
the stimulation of hippocampal neurons with 100 nm 5-ht for 24 hr produced no effect on either the number or the length of primary neurites. |
2015-02-21 |
2023-08-13 |
rat |
| D Chand Basha, N Saya Reddy, M Usha Rani, G Rajarami Redd. Age related changes in aminergic system and behavior following lead exposure: protection with essential metal supplements. Neuroscience research. vol 78. 2015-02-19. PMID:24064391. |
increases in synaptosomal dopamine, epinephrine, norepinephrine and serotonin levels and decrease in mitochondrial monoamine oxidase (mao) in cortex, cerebellum, and hippocampus regions were observed following pb exposure in different age groups (pnd 45, 4, 12 and 18 months) of rats. |
2015-02-19 |
2023-08-12 |
rat |