All Relations between hippocampus and insulin

Publication Sentence Publish Date Extraction Date Species
Camila A E F Cardinali, Yandara A Martins, Ruan C M Moraes, Andressa P Costa, Mayke B Alencar, Ariel M Silber, Andrea S Torrã. Exploring the Therapeutic Potential of Benfotiamine in a Sporadic Alzheimer's-Like Disease Rat Model: Insights into Insulin Signaling and Cognitive function. ACS chemical neuroscience. 2024-07-15. PMID:39007352. we attribute these effects to bft's ability to modulate glucose transporters type 1 and 3 (glut1 and glut3) in the hippocampus, inhibit gsk3 activity in the hippocampus, and modulate the insulin signaling in the hippocampus and entorhinal cortex, as well as reduce the activation of apoptotic pathways (bax) in the hippocampus. 2024-07-15 2024-07-18 rat
Natasha Ivanova, Milena Atanasova, Dora Terzieva, Katerina Georgieva, Jana Tchekalarov. The Role of Piromelatine on Peripheral and Hippocampal Insulin Resistance in Rat Offspring Exposed to Chronic Maternal Stress. International journal of molecular sciences. vol 25. issue 13. 2024-07-13. PMID:39000130. the role of piromelatine on peripheral and hippocampal insulin resistance in rat offspring exposed to chronic maternal stress. 2024-07-13 2024-07-15 rat
Natasha Ivanova, Milena Atanasova, Dora Terzieva, Katerina Georgieva, Jana Tchekalarov. The Role of Piromelatine on Peripheral and Hippocampal Insulin Resistance in Rat Offspring Exposed to Chronic Maternal Stress. International journal of molecular sciences. vol 25. issue 13. 2024-07-13. PMID:39000130. prenatally stressed offspring of both sexes indicated enhanced plasma glucose and serum insulin concentrations, increased homa-ir, and decreased hippocampal glut4 only in male rats. 2024-07-13 2024-07-15 rat
Nathan R Kerr, Chandler W Mossman, Chih-Hsuan Chou, Joshua M Bunten, Taylor J Kelty, Thomas E Childs, R Scott Rector, W David Arnold, Laurel A Grisanti, Xiangwei Du, Frank W Boot. Hindlimb immobilization induces insulin resistance and elevates mitochondrial ROS production in the hippocampus of female rats. Journal of applied physiology (Bethesda, Md. : 1985). 2024-07-04. PMID:38961821. hindlimb immobilization induces insulin resistance and elevates mitochondrial ros production in the hippocampus of female rats. 2024-07-04 2024-07-10 rat
Maryam Moosavi, Roksana Soukhaklari, Saeid Bagheri-Mohammadi, Bita Firouzan, Pegah Javadpour, Rasoul Ghasem. Nanocurcumin prevents memory impairment, hippocampal apoptosis, Akt and CaMKII-α signaling disruption in the central STZ model of Alzheimer's disease in rat. Behavioural brain research. 2024-06-28. PMID:38942084. these findings might suggest that nanocurcumin can restore memory deficit, hippocampal apoptosis as well as akt and camkii-α signaling disruption associated with brain insulin resistance. 2024-06-28 2024-07-01 rat
Iraj Sadri, Saeid Dabbagh Nikookheslat, Pouran Karimi, Mostafa Khani, Sanaz Nadim. Aerobic exercise training improves memory function through modulation of brain-derived neurotrophic factor and synaptic proteins in the hippocampus and prefrontal cortex of type 2 diabetic rats. Journal of diabetes and metabolic disorders. vol 23. issue 1. 2024-06-27. PMID:38932906. defective insulin signaling in the brain may disrupt hippocampal neuroplasticity resulting in learning and memory impairments. 2024-06-27 2024-06-29 rat
Ankita B Jaykumar, Derk Binns, Clinton A Taylor, Anthony Anselmo, Shari G Birnbaum, Kimberly M Huber, Melanie H Cob. WNKs regulate mouse behavior and alter central nervous system glucose uptake and insulin signaling. bioRxiv : the preprint server for biology. 2024-06-25. PMID:38915673. certain areas of the brain involved in episodic memory and behavior, such as the hippocampus, express high levels of insulin receptors and glucose transporter-4 (glut4) and are responsive to insulin. 2024-06-25 2024-06-27 mouse
Ankita B Jaykumar, Derk Binns, Clinton A Taylor, Anthony Anselmo, Shari G Birnbaum, Kimberly M Huber, Melanie H Cob. WNKs regulate mouse behavior and alter central nervous system glucose uptake and insulin signaling. bioRxiv : the preprint server for biology. 2024-06-25. PMID:38915673. inhibition of wnk enhances insulin signaling output and insulin-dependent glut4 trafficking to the plasma membrane in mice primary neuronal cultures and hippocampal slices. 2024-06-25 2024-06-27 mouse
Hooman Hatami, Vahid Reza Askari, Vafa Baradaran Rahimi, Md Saquib Hasnain, Amit Kumar Naya. The Dilemma of Insulin Delivery into the Brain: A Comprehensive Review. Current drug delivery. 2024-06-24. PMID:38910469. the ubiquitous distribution of insulin receptors on various brain cells, such as neurons, microglia, astrocytes, and oligodendrocytes, and their differential localization across various brain regions, including the hippocampus, hypothalamus, and olfactory bulb, collectively underscore the crucial involvement of insulin in the modulation of cerebral functions. 2024-06-24 2024-06-26 human
Bartosz Kula, Botond Antal, Corey Weistuch, Florian Gackière, Alexander Barre, Victor Velado, Jeffrey M Hubbard, Maria Kukley, Lilianne R Mujica-Parodi, Nathan A Smit. D-ꞵ-hydroxybutyrate stabilizes hippocampal CA3-CA1 circuit during acute insulin resistance. PNAS nexus. vol 3. issue 5. 2024-06-01. PMID:38818236. d-ꞵ-hydroxybutyrate stabilizes hippocampal ca3-ca1 circuit during acute insulin resistance. 2024-06-01 2024-06-02 mouse
William H Gendron, Emre Fertan, Kyle M Roddick, Aimée A Wong, Maria Maliougina, Yassine El Hiani, Younes Anini, Richard E Brow. Intranasal insulin treatment ameliorates spatial memory, muscular strength, and frailty deficits in 5xFAD mice. Physiology & behavior. vol 281. 2024-05-25. PMID:38750806. p-akt signaling in the hippocampus was increased by insulin in a dose-dependent manner. 2024-05-25 2024-05-27 mouse
Han-Ming Wu, Yang Vivian Yang, Na-Jun Huang, Li-Ping Fan, Ying-Ying Dai, Ke-Ting Hu, Tian-Yu Tang, Lin Liu, Yue Xu, Dong-Tai Liu, Ze-Xin Cai, Xiao-Yu Niu, Xin-Yi Ren, Zheng-Hao Yao, Hao-Yu Qin, Jian-Zhen Chen, Xi Huang, Cixiong Zhang, Xiang You, Chen Wang, Ying He, Wei Hong, Yu-Xia Sun, Yi-Hong Zhan, Shu-Yong Li. Probucol mitigates high-fat diet-induced cognitive and social impairments by regulating brain redox and insulin resistance. Frontiers in neuroscience. vol 18. 2024-05-08. PMID:38716255. instead, probucol could regulate the levels of nitric oxide and superoxide-generating proteins, and it could specifically alleviate hfd-induced hippocampal insulin resistance. 2024-05-08 2024-05-27 mouse
Punya Sachdeva, Kannan Badri Narayanan, Jitendra Kumar Sinha, Saurabh Gupta, Shampa Ghosh, Krishna Kumar Singh, Rakesh Bhaskar, Abdulmajeed G Almutary, James H Zothantluanga, Kranthi Kumar Kotta, Vinod Kumar Nelson, Ana Cláudia Paiva-Santos, Mosleh Mohammad Abomughaid, Mehnaz Kamal, Danish Iqbal, Mohammed Hamoud ALHarbi, Awadh Aedh ALMutairi, Saikat Dewanjee, Mohana Vamsi Nuli, Shanmugam Vippamakula, Saurabh Kumar Jha, Shreesh Ojha, Niraj Kumar Jh. Recent Advances in Drug Delivery Systems Targeting Insulin Signalling for the Treatment of Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2024-04-12. PMID:38607755. insulin and the downstream insulin signaling molecules are found mainly in the hippocampus and cortex. 2024-04-12 2024-04-15 Not clear
Mubeen A Ansari, Aishah Al-Jarallah, Muddanna S Rao, Ahmed Babiker, Khaled Bensalama. Upregulation of NADPH-oxidase, inducible nitric oxide synthase and apoptosis in the hippocampus following impaired insulin signaling in the rats: Development of sporadic Alzheimer's disease. Brain research. 2024-03-29. PMID:38552936. upregulation of nadph-oxidase, inducible nitric oxide synthase and apoptosis in the hippocampus following impaired insulin signaling in the rats: development of sporadic alzheimer's disease. 2024-03-29 2024-04-01 rat
Hadi Moatamed Jahromi, Ali Rafati, Saied Karbalay-Doust, Somaye Keshavarz, Maryam Nase. The combination treatment of hypothermia and intranasal insulin ameliorates the structural and functional changes in a rat model of traumatic brain injury. Brain structure & function. 2024-03-18. PMID:38498064. the present study aimed to investigate the combination effects of hypothermia (ht) and intranasal insulin (ins) on structural changes of the hippocampus and cognitive impairments in the traumatic brain injury (tbi) rat model. 2024-03-18 2024-03-20 rat
Daymara Mercerón-Martínez, Laura Alacán Ricardo, Arturo Bejerano Pina, Norma Orama Rojo, Ariel Expósito Seco, Yamilé Vega Hurtado, Bárbara Estupiñán Días, Isabel Fernández, Laura García Pupo, Marquiza Sablón Carrazana, Chryslaine Rodríguez-Tanty, Roberto Menéndez Soto Del Valle, William Almaguer-Melia. Amylovis-201 enhances physiological memory formation and rescues memory and hippocampal cell loss in a streptozotocin-induced Alzheimer's disease animal model. Brain research. 2024-03-03. PMID:38432261. furthermore, daily administration of amylovis-201 to animals with bilateral intracerebroventricular injection of stz produces a reduction in the loss of the hippocampus dentate gyrus cells and an improvement in spatial memory, probably because amylovis-201 can interact with some of the protein kinases of the insulin signaling cascade, also involved in neural plasticity, and thereby halt or reverse some of the effects of stz. 2024-03-03 2024-03-06 Not clear
Amanda Brondani Mucellini, Daniela Pereira Laureano, Márcio Bonesso Alves, Roberta Dalle Molle, Mariana Balbinot Borges, Ana Paula da Ascenção Salvador, Irina Pokhvisneva, Gisele Gus Manfro, Patrícia Pelufo Silveir. The impact of poor fetal growth and chronic hyperpalatable diet exposure in adulthood on hippocampal function and feeding patterns in male rats. Developmental psychobiology. vol 66. issue 2. 2024-02-19. PMID:38372503. we investigated whether poor fetal growth and exposure to chronic hyperpalatable food in adulthood could influence the recognition of environmental and food cues, eating behavior patterns, and hippocampal insulin signaling. 2024-02-19 2024-02-21 rat
Amanda Brondani Mucellini, Daniela Pereira Laureano, Márcio Bonesso Alves, Roberta Dalle Molle, Mariana Balbinot Borges, Ana Paula da Ascenção Salvador, Irina Pokhvisneva, Gisele Gus Manfro, Patrícia Pelufo Silveir. The impact of poor fetal growth and chronic hyperpalatable diet exposure in adulthood on hippocampal function and feeding patterns in male rats. Developmental psychobiology. vol 66. issue 2. 2024-02-19. PMID:38372503. poor fetal growth and chronic hfs diet in adulthood altered hippocampal insulin signaling and eating patterns, diminishing the flexibility associated with eating behavior in response to extrinsic changes in food availability in the environment. 2024-02-19 2024-02-21 rat
Filipe Valvassori do Nascimento, Betânia Souza de Freitas, Maiara Priscila Dos Passos, Luiza Kleverston, Cristophod de Souza Dos Santos, Luiza Wilges Kist, Maurício Reis Bogo, Elke Bromberg, Nadja Schröde. A high fat diet potentiates neonatal iron overload-induced memory impairments in rats. European journal of nutrition. 2024-02-15. PMID:38358514. iron overload and exposure to a hypercaloric/hyperlipidic diet, on cognition, insulin resistance, and hippocampal glut1, glut3, insr mrna expression, and akt phosporylation. 2024-02-15 2024-02-17 rat
Mubeen A Ansari, Muddanna Sakkattu Rao, Aishah Al-Jaralla. Insights into early pathogenesis of sporadic Alzheimer's disease: role of oxidative stress and loss of synaptic proteins. Frontiers in neuroscience. vol 17. 2024-01-23. PMID:38260013. this study evaluated early hippocampal oxidative stress, pre- and post-synaptic proteins in intraperitoneal (ip) and intracerebroventricular (icv) streptozotocin (stz) models of impaired insulin signaling. 2024-01-23 2024-01-25 rat