Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
J M Dubinsk. Intracellular calcium levels during the period of delayed excitotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 2. 1993-03-04. PMID:8093901. |
intracellular calcium concentrations ([ca2+]i) among cultured hippocampal neurons were monitored during and in the hours following an excitotoxic glutamate application to determine the time course of changes involved in delayed excitotoxicity. |
1993-03-04 |
2023-08-12 |
Not clear |
A Héron, F Lasbennes, J Seyla. Effect of two different routes of administration of R-PIA on glutamate release during ischemia. Neuroscience letters. vol 147. issue 2. 1993-03-02. PMID:1491809. |
extracellular hippocampal glutamate was sampled by microdialysis and measured by hplc. |
1993-03-02 |
2023-08-11 |
rat |
A Héron, F Lasbennes, J Seyla. Effect of two different routes of administration of R-PIA on glutamate release during ischemia. Neuroscience letters. vol 147. issue 2. 1993-03-02. PMID:1491809. |
conversely, r-pia (100 microm) continuously infused through the hippocampal dialysis probe did not significantly modify glutamate efflux. |
1993-03-02 |
2023-08-11 |
rat |
S Dolina, J Peeling, G Sutherland, N Pillay, A Greenber. Effect of sustained pyridoxine treatment on seizure susceptibility and regional brain amino acid levels in genetically epilepsy-prone BALB/c mice. Epilepsia. vol 34. issue 1. 1993-02-25. PMID:8422860. |
[1h] nuclear magnetic resonance (nmr) spectroscopy of perchloric acid extracts of tissue was used to determine the concentrations of several compounds [n-acetylaspartate (naa), gaba, glutamate, aspartate, alanine, taurine, creatine, cholines, inositol] in the hippocampus, neocortex, brainstem, and cerebellum of untreated and pyridoxine-treated 6-week-old female animals. |
1993-02-25 |
2023-08-12 |
mouse |
D G Winder, P J Con. Activation of metabotropic glutamate receptors increases cAMP accumulation in hippocampus by potentiating responses to endogenous adenosine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 1. 1993-02-24. PMID:8380851. |
activation of metabotropic glutamate receptors increases camp accumulation in hippocampus by potentiating responses to endogenous adenosine. |
1993-02-24 |
2023-08-12 |
rat |
T Falkenberg, P Ernfors, H Persson, N Lindefor. Cortical transynaptic activation of tyrosine kinase receptor trkB messenger RNA expression in rat hippocampus. Neuroscience. vol 51. issue 4. 1993-02-23. PMID:1488128. |
we suggest that glutamate release from cortical afferents to the hippocampus has the capacity to increase neuronal expression of trkb messenger rna within the hippocampus. |
1993-02-23 |
2023-08-11 |
rat |
P Jonas, B Sakman. Glutamate receptor channels in isolated patches from CA1 and CA3 pyramidal cells of rat hippocampal slices. The Journal of physiology. vol 455. 1993-02-17. PMID:1282929. |
glutamate receptor channels in isolated patches from ca1 and ca3 pyramidal cells of rat hippocampal slices. |
1993-02-17 |
2023-08-11 |
rat |
P Jonas, B Sakman. Glutamate receptor channels in isolated patches from CA1 and CA3 pyramidal cells of rat hippocampal slices. The Journal of physiology. vol 455. 1993-02-17. PMID:1282929. |
currents activated by glutamate receptor (glur) agonists were recorded from outside-out patches isolated from the soma of visually identified pyramidal neurones of the ca3 and ca1 region of rat hippocampal slices. |
1993-02-17 |
2023-08-11 |
rat |
D P McLaughlin, M E Cheetham, R W Kerwi. Expression of alternatively-spliced glutamate receptors in human hippocampus. European journal of pharmacology. vol 244. issue 1. 1993-02-12. PMID:8420792. |
expression of alternatively-spliced glutamate receptors in human hippocampus. |
1993-02-12 |
2023-08-12 |
human |
M A Desai, T S Smith, P J Con. Multiple metabotropic glutamate receptors regulate hippocampal function. Synapse (New York, N.Y.). vol 12. issue 3. 1993-02-11. PMID:1336225. |
multiple metabotropic glutamate receptors regulate hippocampal function. |
1993-02-11 |
2023-08-11 |
Not clear |
M A Desai, T S Smith, P J Con. Multiple metabotropic glutamate receptors regulate hippocampal function. Synapse (New York, N.Y.). vol 12. issue 3. 1993-02-11. PMID:1336225. |
selective activation of metabotropic glutamate receptors with trans-1-amino-1,3-cyclopentanedicarboxylic acid (trans-acpd) stimulates phosphoinositide hydrolysis and elicits three major physiological responses in area ca1 of the hippocampus. |
1993-02-11 |
2023-08-11 |
Not clear |
M A Desai, T S Smith, P J Con. Multiple metabotropic glutamate receptors regulate hippocampal function. Synapse (New York, N.Y.). vol 12. issue 3. 1993-02-11. PMID:1336225. |
thus, our data are consistent with the hypothesis that the physiological effects of trans-acpd in area ca1 of the hippocampus are mediated by metabotropic glutamate receptors that are distinct from the ap3-sensitive phosphoinositide hydrolysis-linked glutamate receptor. |
1993-02-11 |
2023-08-11 |
Not clear |
Y Bessho, H Nawa, S Nakanish. Glutamate and quisqualate regulate expression of metabotropic glutamate receptor mRNA in cultured cerebellar granule cells. Journal of neurochemistry. vol 60. issue 1. 1993-01-25. PMID:8093260. |
metabotropic glutamate receptor (type 1; mglur1) is expressed predominantly in the hippocampus and the cerebellum. |
1993-01-25 |
2023-08-12 |
Not clear |
D Lekieffre, J Callebert, M Plotkine, M Allix, R G Boul. Enhancement of endogenous excitatory amino acids by theophylline does not modify the behavioral and histological consequences of forebrain ischemia. Brain research. vol 565. issue 2. 1993-01-19. PMID:1842703. |
despite an increase in the release of glutamate in the hippocampus during ischemia, theophylline did not alter the neurological and histological outcomes. |
1993-01-19 |
2023-08-11 |
rat |
M Raiteri, R Costa, M March. Effects of oxiracetam on neurotransmitter release from rat hippocampus slices and synaptosomes. Neuroscience letters. vol 145. issue 1. 1993-01-13. PMID:1361044. |
thus oxiracetam may selectively increase the release of glutamate and acetylcholine in hippocampus by a mechanism which appears not to be sited in the releasing nerve terminals. |
1993-01-13 |
2023-08-11 |
rat |
B S Meldrum, J H Swan, M J Leach, M H Millan, R Gwinn, K Kadota, S H Graham, J Chen, R P Simo. Reduction of glutamate release and protection against ischemic brain damage by BW 1003C87. Brain research. vol 593. issue 1. 1993-01-08. PMID:1458310. |
in anaesthetised rats with microdialysis probes implanted in the dorsal hippocampus the increase in extracellular glutamate evoked by veratrine is markedly reduced by co-infusion of bw 1003c87, 100 microm. |
1993-01-08 |
2023-08-11 |
rat |
R F Villa, R Arnaboldi, B Ghigini, A Gorin. Mitochondrial factors involved in Parkinson's disease by MPTP toxicity in Macaca fascicularis and drug effect. Neurochemical research. vol 17. issue 11. 1993-01-08. PMID:1461362. |
the maximal rates (vmax) of some mitochondrial enzyme activities related to energy transduction (citrate synthase, succinate dehydrogenase, malate dehydrogenase, nadh-cytochrome c reductase, cytochrome oxidase) and amino acid metabolism (glutamate dehydrogenase, glutamate-pyruvate- and glutamate-oxaloacetate- transaminases) were evaluated in non-synaptic ("free") and intrasynaptic "light" and "heavy" mitochondria from hippocampus of macaca fascicularis (cynomolgus monkey). |
1993-01-08 |
2023-08-11 |
monkey |
V Boss, M A Desai, T S Smith, P J Con. Trans-ACPD-induced phosphoinositide hydrolysis and modulation of hippocampal pyramidal cell excitability do not undergo parallel developmental regulation. Brain research. vol 594. issue 2. 1993-01-07. PMID:1360322. |
the selective metabotropic glutamate receptor agonist, trans-1-aminocyclopentane-1,3-dicarboxylic acid (trans-acpd), stimulates phosphoinositide hydrolysis and elicits a number of electrophysiological responses in the hippocampus. |
1993-01-07 |
2023-08-11 |
rat |
G Tocco, A J Annala, M Baudry, R F Thompso. Learning of a hippocampal-dependent conditioning task changes the binding properties of AMPA receptors in rabbit hippocampus. Behavioral and neural biology. vol 58. issue 3. 1993-01-06. PMID:1280948. |
we previously demonstrated that the binding of [3h]ampa to the ampa subtype of glutamate receptors was selectively increased in hippocampus following classical conditioning of the rabbit nictitating membrane response in a delay paradigm. |
1993-01-06 |
2023-08-11 |
rabbit |
G Tocco, A J Annala, M Baudry, R F Thompso. Learning of a hippocampal-dependent conditioning task changes the binding properties of AMPA receptors in rabbit hippocampus. Behavioral and neural biology. vol 58. issue 3. 1993-01-06. PMID:1280948. |
these results support the hypothesis that changes in hippocampal glutamate receptors are a corollary of synaptic plasticity in certain forms of learning. |
1993-01-06 |
2023-08-11 |
rabbit |