| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A N Katchman, N Hershkowit. Adenosine A1 antagonism increases specific synaptic forms of glutamate release during anoxia, revealing a unique source of excitation. Hippocampus. vol 6. issue 3. 1996-12-30. PMID:8841822. |
the role of the adenosine a1 receptor in the modulation of anoxia-induced synaptic glutamate release was examined in ca1 pyramidal neurons by whole-cell voltage-clamp recording in the rat hippocampal slice preparation. |
1996-12-30 |
2023-08-12 |
rat |
| A S Lesage, L Peeters, J E Leyse. Lubeluzole, a novel long-term neuroprotectant, inhibits the glutamate-activated nitric oxide synthase pathway. The Journal of pharmacology and experimental therapeutics. vol 279. issue 2. 1996-12-24. PMID:8930181. |
we studied the mechanism of protection of lubeluzole against glutamate toxicity in primary hippocampal cell cultures. |
1996-12-24 |
2023-08-12 |
rat |
| A S Lesage, L Peeters, J E Leyse. Lubeluzole, a novel long-term neuroprotectant, inhibits the glutamate-activated nitric oxide synthase pathway. The Journal of pharmacology and experimental therapeutics. vol 279. issue 2. 1996-12-24. PMID:8930181. |
in conclusion, the long-term neuroprotective property of lubeluzole against glutamate toxicity in hippocampal cultures is reflected by the fact of interference with the glutamateactivated nitric oxide synthase pathway. |
1996-12-24 |
2023-08-12 |
rat |
| D G MacGregor, M J Higgins, P A Jones, W L Maxwell, M W Watson, D I Graham, T W Ston. Ascorbate attenuates the systemic kainate-induced neurotoxicity in the rat hippocampus. Brain research. vol 727. issue 1-2. 1996-12-23. PMID:8842391. |
ascorbate did not modify synaptically evoked potentials or long-term potentiation in hippocampal slices, ruling out any blocking activity at glutamate receptors. |
1996-12-23 |
2023-08-12 |
rat |
| M Johnson, R H Perry, M A Piggott, J A Court, D Spurden, S Lloyd, P G Ince, E K Perr. Glutamate receptor binding in the human hippocampus and adjacent cortex during development and aging. Neurobiology of aging. vol 17. issue 4. 1996-12-20. PMID:8832639. |
glutamate receptor binding in the human hippocampus and adjacent cortex during development and aging. |
1996-12-20 |
2023-08-12 |
human |
| M Johnson, R H Perry, M A Piggott, J A Court, D Spurden, S Lloyd, P G Ince, E K Perr. Glutamate receptor binding in the human hippocampus and adjacent cortex during development and aging. Neurobiology of aging. vol 17. issue 4. 1996-12-20. PMID:8832639. |
the transient peaks of receptor binding are likely to reflect processes of synaptogenesis and pruning and may provide clues regarding the role of the different glutamate receptor subtypes in various pathologies of the hippocampus and adjacent cortex associated with developmental disorders (of genetic origin or due to perinatal trauma or insult). |
1996-12-20 |
2023-08-12 |
human |
| C F Zorumski, S Mennerick, J Qu. Modulation of excitatory synaptic transmission by low concentrations of glutamate in cultured rat hippocampal neurons. The Journal of physiology. vol 494 ( Pt 2). 1996-12-20. PMID:8842005. |
modulation of excitatory synaptic transmission by low concentrations of glutamate in cultured rat hippocampal neurons. |
1996-12-20 |
2023-08-12 |
rat |
| C F Zorumski, S Mennerick, J Qu. Modulation of excitatory synaptic transmission by low concentrations of glutamate in cultured rat hippocampal neurons. The Journal of physiology. vol 494 ( Pt 2). 1996-12-20. PMID:8842005. |
the effects of low micromolar concentrations of glutamate on fast excitatory synaptic responses were studied in microcultures of postnatal rat hippocampal neurons using whole-cell patch clamp recordings. |
1996-12-20 |
2023-08-12 |
rat |
| T Hama, M Murayama, R Kato, A Ohtake, K Sat. Amphiphilic helix is essential for the activity of brain injury-derived neurotrophic peptide (BINP). FEBS letters. vol 396. issue 2-3. 1996-12-20. PMID:8914976. |
neurotrophic activities of binp and its analogs were estimated from the effects on supporting septal cholinergic neurons and on rescuing hippocampal neurons from injury caused by glutamate. |
1996-12-20 |
2023-08-12 |
Not clear |
| D J Healy, J H Meador-Woodruf. Dopamine receptor gene expression in hippocampus is differentially regulated by the NMDA receptor antagonist MK-801. European journal of pharmacology. vol 306. issue 1-3. 1996-12-18. PMID:8813639. |
glutamate agonists have been shown to stimulate the release of dopamine in the striatum, while the nmda receptor antagonist mk-801 has been shown to cause an increase in extracellular dopamine in the hippocampus. |
1996-12-18 |
2023-08-12 |
rat |
| D J Healy, J H Meador-Woodruf. Dopamine receptor gene expression in hippocampus is differentially regulated by the NMDA receptor antagonist MK-801. European journal of pharmacology. vol 306. issue 1-3. 1996-12-18. PMID:8813639. |
mk-801 caused changes in dopamine d1, d2, d3, and d4 receptor gene expression in a complex manner that suggests that dopamine receptor gene expression in the hippocampus may be differentially regulated by glutamate, via the nmda receptor. |
1996-12-18 |
2023-08-12 |
rat |
| T Ohtsuki, M Matsumoto, K Kitagawa, T Mabuchi, K Mandai, K Matsushita, K Kuwabara, M Tagaya, S Ogawa, H Ueda, T Kamada, T Yanagihar. Delayed neuronal death in ischemic hippocampus involves stimulation of protein tyrosine phosphorylation. The American journal of physiology. vol 271. issue 4 Pt 1. 1996-12-16. PMID:8897814. |
transient forebrain ischemia for 5-10 min in mongolian gerbils or intoxication with the glutamate analogue kainic acid (12 mg/kg) in sprague-dawley rats caused neuronal death selectively in the hippocampus 2-4 days or 1 day later, respectively. |
1996-12-16 |
2023-08-12 |
rat |
| T Ohtsuki, M Matsumoto, K Kitagawa, T Mabuchi, K Mandai, K Matsushita, K Kuwabara, M Tagaya, S Ogawa, H Ueda, T Kamada, T Yanagihar. Delayed neuronal death in ischemic hippocampus involves stimulation of protein tyrosine phosphorylation. The American journal of physiology. vol 271. issue 4 Pt 1. 1996-12-16. PMID:8897814. |
the results suggest that protein tyrosine phosphorylation might propagate delayed neuronal death in the mature hippocampus through glutamate overload after ischemia-reperfusion. |
1996-12-16 |
2023-08-12 |
rat |
| J T Porter, K D McCarth. Hippocampal astrocytes in situ respond to glutamate released from synaptic terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 16. 1996-12-13. PMID:8756437. |
hippocampal astrocytes in situ respond to glutamate released from synaptic terminals. |
1996-12-13 |
2023-08-12 |
Not clear |
| J T Porter, K D McCarth. Hippocampal astrocytes in situ respond to glutamate released from synaptic terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 16. 1996-12-13. PMID:8756437. |
overall, the results indicate that hippocampal astrocytes in situ are able to respond to the neuronal release of the neurotransmitter glutamate with increases in [ca2+]i. |
1996-12-13 |
2023-08-12 |
Not clear |
| S Himmelseher, E Pfenninger, M Georgief. The effect of basic fibroblast growth factor on glutamate-injured neuroarchitecture and arachidonic acid release in adult hippocampal neurons. Brain research. vol 707. issue 1. 1996-12-13. PMID:8866713. |
we investigated the effects of bfgf on mature, differentiated rat hippocampal neurons cultured for 10-12 days after an 8-min exposure to 500 microm glutamate. |
1996-12-13 |
2023-08-12 |
rat |
| D Krajnc, N H Neff, M Hadjiconstantino. Glutamate, glutamine and glutamine synthetase in the neonatal rat brain following hypoxia. Brain research. vol 707. issue 1. 1996-12-13. PMID:8866724. |
exposing 7-day-old rat pups to hypoxia, 8% oxygen/92% nitrogen, for 3 h alters glutamate (glu), glutamine and glutamine synthetase (gs) activity in the striatum, frontal cortex and hippocampus. |
1996-12-13 |
2023-08-12 |
rat |
| M Grilli, M Pizzi, M Memo, P Span. Neuroprotection by aspirin and sodium salicylate through blockade of NF-kappaB activation. Science (New York, N.Y.). vol 274. issue 5291. 1996-12-13. PMID:8910280. |
at concentrations compatible with amounts in plasma during chronic anti-inflammatory therapy, acetylsalicylic acid and its metabolite sodium salicylate were found to be protective against neurotoxicity elicited by the excitatory amino acid glutamate in rat primary neuronal cultures and hippocampal slices. |
1996-12-13 |
2023-08-12 |
rat |
| W Paschen, J Schmitt, A Ut. RNA editing of glutamate receptor subunits GluR2, GluR5 and GluR6 in transient cerebral ischemia in the rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 16. issue 4. 1996-12-13. PMID:8964793. |
after 30 min of ischemia, brains were recirculated for 4, 8, or 24 h. total rna was extracted from the cortex, striatum, and hippocampus in order to analyze the extent of mrna editing of the glutamate receptor subunits glur2, glur5, and glur6. |
1996-12-13 |
2023-08-12 |
rat |
| A Rump, C Sommer, P Gass, S Bele, D Meissner, M Kiesslin. Editing of GluR2 RNA in the gerbil hippocampus after global cerebral ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 16. issue 6. 1996-12-11. PMID:8898712. |
postischemic delayed neuronal death (dnd) in ca1 of the gerbil hippocampus is thought to be caused by an abnormal increase of ca2+ influx into the cell, mediated by excessive activation of glutamate receptors. |
1996-12-11 |
2023-08-12 |
Not clear |