| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A N Van Den Pol, K Obrietan, A Belouso. Glutamate hyperexcitability and seizure-like activity throughout the brain and spinal cord upon relief from chronic glutamate receptor blockade in culture. Neuroscience. vol 74. issue 3. 1997-01-30. PMID:8884763. |
to determine whether parallel glutamate-mediated hyperexcitability and seizure-like activity in the rat can be generated by neurons irrespective of their origin within the cns, we maintained cells from the spinal cord,hippocampus, olfactory bulb, striatum, hypothalamus, and cortex in the long-term presence of glutamate receptor antagonists 2-amino-5-phosphonovalerate and 6-cyano-7-nitroquinoxaline-2-3-dione. |
1997-01-30 |
2023-08-12 |
rat |
| A N Van Den Pol, K Obrietan, A Belouso. Glutamate hyperexcitability and seizure-like activity throughout the brain and spinal cord upon relief from chronic glutamate receptor blockade in culture. Neuroscience. vol 74. issue 3. 1997-01-30. PMID:8884763. |
sufficient amounts of glutamate can be released from axon terminals from all areas to cause cell hippocampal and cortical neurons, but also by neurons from any of the brain regions tested after chronic deprivation of glutamate receptor stimulation during development. |
1997-01-30 |
2023-08-12 |
rat |
| M M Nicolle, J L Bizon, M Gallaghe. In vitro autoradiography of ionotropic glutamate receptors in hippocampus and striatum of aged Long-Evans rats: relationship to spatial learning. Neuroscience. vol 74. issue 3. 1997-01-30. PMID:8884770. |
in vitro autoradiography of ionotropic glutamate receptors in hippocampus and striatum of aged long-evans rats: relationship to spatial learning. |
1997-01-30 |
2023-08-12 |
rat |
| X Li, O Orwar, C Revesjö, M Sandber. Gamma-glutamyl peptides and related amino acids in rat hippocampus in vitro: effect of depolarization and gamma-glutamyl transpeptidase inhibition. Neurochemistry international. vol 29. issue 2. 1997-01-29. PMID:8837040. |
the concentrations of gamma-glutamylglutamate, gamma-glutamylglutamine, gamma-glutamylcysteine, glutamate, aspartate, glutamine, cyst(e)ine and glutathione (including disulfides) were determined by hplc analysis of both the tissue and the surrounding medium of incubated rat hippocampal slices. |
1997-01-29 |
2023-08-12 |
rat |
| D M Armstrong, M D Ikonomovi. AMPA-selective glutamate receptor subtype immunoreactivity in the hippocampal dentate gyrus of patients with Alzheimer disease. Evidence for hippocampal plasticity. Molecular and chemical neuropathology. vol 28. issue 1-3. 1997-01-23. PMID:8871942. |
ampa-selective glutamate receptor subtype immunoreactivity in the hippocampal dentate gyrus of patients with alzheimer disease. |
1997-01-23 |
2023-08-12 |
Not clear |
| C Behl, F Lezoualc'h, T Trapp, M Widmann, T Skutella, F Holsboe. Glucocorticoids enhance oxidative stress-induced cell death in hippocampal neurons in vitro. Endocrinology. vol 138. issue 1. 1997-01-23. PMID:8977391. |
two oxidative stressors were investigated, the free radical-inducing alzheimer's disease-associated amyloid beta-protein, which is toxic to hippocampal neurons, and the excitatory amino acid glutamate, which induces oxidative cell death in ht22 cells via an increase in intracellular peroxides. |
1997-01-23 |
2023-08-12 |
mouse |
| C Behl, F Lezoualc'h, T Trapp, M Widmann, T Skutella, F Holsboe. Glucocorticoids enhance oxidative stress-induced cell death in hippocampal neurons in vitro. Endocrinology. vol 138. issue 1. 1997-01-23. PMID:8977391. |
glucocorticoids strongly increased the vulnerability of the hippocampal cells to amyloid beta-protein and glutamate. |
1997-01-23 |
2023-08-12 |
mouse |
| D E Pellegrini-Giampietro, S A Torregrossa, F Moron. Pharmacological characterization of metabotropic glutamate receptors coupled to phospholipase D in the rat hippocampus. British journal of pharmacology. vol 118. issue 4. 1997-01-17. PMID:8799579. |
pharmacological characterization of metabotropic glutamate receptors coupled to phospholipase d in the rat hippocampus. |
1997-01-17 |
2023-08-12 |
rat |
| J P de Bruin, F Facchinetti, E Toth, R Balazs, R N Jooste. Differential effects of learning and recall of a spatial task on phosphoinositide hydrolysis induced by the metabotropic glutamate receptor agonist 1S,3R-ACPD (1S,3R-1-amino-cyclopentane-1,3-discarboxylic acid) in the hippocampus and the prefrontal cortex of rats. Neuroscience letters. vol 204. issue 1-2. 1997-01-17. PMID:8929977. |
differential effects of learning and recall of a spatial task on phosphoinositide hydrolysis induced by the metabotropic glutamate receptor agonist 1s,3r-acpd (1s,3r-1-amino-cyclopentane-1,3-discarboxylic acid) in the hippocampus and the prefrontal cortex of rats. |
1997-01-17 |
2023-08-12 |
rat |
| J P de Bruin, F Facchinetti, E Toth, R Balazs, R N Jooste. Differential effects of learning and recall of a spatial task on phosphoinositide hydrolysis induced by the metabotropic glutamate receptor agonist 1S,3R-ACPD (1S,3R-1-amino-cyclopentane-1,3-discarboxylic acid) in the hippocampus and the prefrontal cortex of rats. Neuroscience letters. vol 204. issue 1-2. 1997-01-17. PMID:8929977. |
phosphoinositide (pi) hydrolysis, stimulated by 1s,3r-1-amino-cyclopentane-1,3-dicarboxylic acid (1s,3r-acpd), an agonist of metabotropic glutamate receptors (mglurs), was measured in hippocampal and prefrontal cortical slices obtained from rats which had been trained for 8 days in a morris water maze and had learned an allocentric spatial task. |
1997-01-17 |
2023-08-12 |
rat |
| R J Cormier, P T Kell. Glutamate-induced long-term potentiation enhances spontaneous EPSC amplitude but not frequency. Journal of neurophysiology. vol 75. issue 5. 1997-01-16. PMID:8734590. |
ltp also is induced by direct glutamate iontophoresis (1 m, 1-2 microa, 10 s) onto postsynaptic neurons in hippocampal slices without evoked presynaptic stimulation; this form of ltp is called "ionto-ltp". |
1997-01-16 |
2023-08-12 |
Not clear |
| M W Fleck, R Bähring, D K Patneau, M L Maye. AMPA receptor heterogeneity in rat hippocampal neurons revealed by differential sensitivity to cyclothiazide. Journal of neurophysiology. vol 75. issue 6. 1997-01-15. PMID:8793745. |
the kinetics of onset of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor desensitization by glutamate, and the extent of attenuation of ampa receptor desensitization by cyclothiazide, showed pronounced cell-to-cell variation in cultures of rat hippocampal neurons. |
1997-01-15 |
2023-08-12 |
rat |
| P Mullany, S Connolly, M A Lync. Ageing is associated with changes in glutamate release, protein tyrosine kinase and Ca2+/calmodulin-dependent protein kinase II in rat hippocampus. European journal of pharmacology. vol 309. issue 3. 1997-01-15. PMID:8874156. |
ageing is associated with changes in glutamate release, protein tyrosine kinase and ca2+/calmodulin-dependent protein kinase ii in rat hippocampus. |
1997-01-15 |
2023-08-12 |
rat |
| P Mullany, S Connolly, M A Lync. Ageing is associated with changes in glutamate release, protein tyrosine kinase and Ca2+/calmodulin-dependent protein kinase II in rat hippocampus. European journal of pharmacology. vol 309. issue 3. 1997-01-15. PMID:8874156. |
we have used synaptosomes prepared from rat hippocampus to investigate the role of protein tyrosine kinase and ca2+/calmodulin-dependent protein kinase ii in modulating glutamate release in young animals and to investigate possible parallel age-related changes in release and kinase activity. |
1997-01-15 |
2023-08-12 |
rat |
| P Mullany, S Connolly, M A Lync. Ageing is associated with changes in glutamate release, protein tyrosine kinase and Ca2+/calmodulin-dependent protein kinase II in rat hippocampus. European journal of pharmacology. vol 309. issue 3. 1997-01-15. PMID:8874156. |
k(+)-stimulated release of glutamate was significantly decreased in hippocampal synaptosomes prepared from aged, compared to young, animals. |
1997-01-15 |
2023-08-12 |
rat |
| P Mullany, S Connolly, M A Lync. Ageing is associated with changes in glutamate release, protein tyrosine kinase and Ca2+/calmodulin-dependent protein kinase II in rat hippocampus. European journal of pharmacology. vol 309. issue 3. 1997-01-15. PMID:8874156. |
we conclude that these kinases play a role in modulating release of glutamate in hippocampus and that the age-related decrease in glutamate release may be partly due to an age-related decrease in kinase activities. |
1997-01-15 |
2023-08-12 |
rat |
| B McGahon, M A Lync. The synergism between ACPD and arachidonic acid on glutamate release in hippocampus is age-dependent. European journal of pharmacology. vol 309. issue 3. 1997-01-15. PMID:8874158. |
the synergism between acpd and arachidonic acid on glutamate release in hippocampus is age-dependent. |
1997-01-15 |
2023-08-12 |
rat |
| B McGahon, M A Lync. The synergism between ACPD and arachidonic acid on glutamate release in hippocampus is age-dependent. European journal of pharmacology. vol 309. issue 3. 1997-01-15. PMID:8874158. |
activation of the metabotropic glutamate receptor by the specific agonist trans-1-amino-cyclopentyl-1,3-dicarboxylate (acpd) increases release of glutamate and activation of protein kinase c in the presence of a low concentration of arachidonic acid in hippocampal synaptosomes prepared from 4-month-old rats. |
1997-01-15 |
2023-08-12 |
rat |
| B McGahon, M A Lync. The synergism between ACPD and arachidonic acid on glutamate release in hippocampus is age-dependent. European journal of pharmacology. vol 309. issue 3. 1997-01-15. PMID:8874158. |
the finding that the interaction between arachidonic acid and acpd on release was absent in synaptosomes prepared in the presence of heparin, an antagonist at inositol trisphosphate receptors, suggests that mobilization of intracellular calcium stores plays a role in the synergism between arachidonic acid and acpd on [3h]glutamate release in hippocampal synaptosomes. |
1997-01-15 |
2023-08-12 |
rat |
| I M Kapetanovic, W D Yonekawa, H J Kupferber. The effects of D-23129, a new experimental anticonvulsant drug, on neurotransmitter amino acids in the rat hippocampus in vitro. Epilepsy research. vol 22. issue 3. 1997-01-15. PMID:8991783. |
their effects on de novo synthesis of excitatory (glutamate and aspartate) and inhibitory (gaba) amino acids were studied in rat hippocampal slices. |
1997-01-15 |
2023-08-12 |
rat |