| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A I Breukel, E Besselsen, F H Lopes da Silva, W E Ghijse. Arachidonic acid inhibits uptake of amino acids and potentiates PKC effects on glutamate, but not GABA, exocytosis in isolated hippocampal nerve terminals. Brain research. vol 773. issue 1-2. 1998-01-27. PMID:9409709. |
arachidonic acid inhibits uptake of amino acids and potentiates pkc effects on glutamate, but not gaba, exocytosis in isolated hippocampal nerve terminals. |
1998-01-27 |
2023-08-12 |
rat |
| A I Breukel, E Besselsen, F H Lopes da Silva, W E Ghijse. Arachidonic acid inhibits uptake of amino acids and potentiates PKC effects on glutamate, but not GABA, exocytosis in isolated hippocampal nerve terminals. Brain research. vol 773. issue 1-2. 1998-01-27. PMID:9409709. |
arachidonic acid (aa), the putative retrograde messenger in long-term potentiation, enhanced extracellular aspartate, glutamate, and gaba levels in rat hippocampus synaptosomes. |
1998-01-27 |
2023-08-12 |
rat |
| A I Breukel, E Besselsen, F H Lopes da Silva, W E Ghijse. Arachidonic acid inhibits uptake of amino acids and potentiates PKC effects on glutamate, but not GABA, exocytosis in isolated hippocampal nerve terminals. Brain research. vol 773. issue 1-2. 1998-01-27. PMID:9409709. |
when stimulating hippocampus synaptosomes with 4-aminopyridine, aa (2 microm) potentiated the ca2+-dependent release of glutamate, but not of gaba, synergistically with pkc activation by 4beta-phorbol-12,13-dibutyric acid. |
1998-01-27 |
2023-08-12 |
rat |
| A I Breukel, E Besselsen, F H Lopes da Silva, W E Ghijse. Arachidonic acid inhibits uptake of amino acids and potentiates PKC effects on glutamate, but not GABA, exocytosis in isolated hippocampal nerve terminals. Brain research. vol 773. issue 1-2. 1998-01-27. PMID:9409709. |
in rat hippocampus, aa exerts different presynaptic effects to regulate extracellular amino acid levels, by inhibiting carrier-mediated uptake and, for glutamate, by stimulating exocytosis. |
1998-01-27 |
2023-08-12 |
rat |
| R Bernabeu, M Cammarota, I Izquierdo, J H Medin. Involvement of hippocampal AMPA glutamate receptor changes and the cAMP/protein kinase A/CREB-P signalling pathway in memory consolidation of an avoidance task in rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 30. issue 8. 1998-01-26. PMID:9361725. |
involvement of hippocampal ampa glutamate receptor changes and the camp/protein kinase a/creb-p signalling pathway in memory consolidation of an avoidance task in rats. |
1998-01-26 |
2023-08-12 |
rat |
| R Bernabeu, M Cammarota, I Izquierdo, J H Medin. Involvement of hippocampal AMPA glutamate receptor changes and the cAMP/protein kinase A/CREB-P signalling pathway in memory consolidation of an avoidance task in rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 30. issue 8. 1998-01-26. PMID:9361725. |
training in step-down inhibitory avoidance (0.3-ma footshock) is followed by biochemical changes in rat hippocampus that strongly suggest an involvement of quantitative changes in glutamate ampa receptors, followed by changes in the dopamine d1 receptor/camp/ protein kinase a (pka)/creb-p signalling pathway in memory consolidation. |
1998-01-26 |
2023-08-12 |
rat |
| M L Ruehr, L Zhang, R V Dorma. Lipid-dependent modulation of Ca2+ availability in isolated mossy fiber nerve endings. Neurochemical research. vol 22. issue 10. 1998-01-22. PMID:9342725. |
an enhancement of glutamate release from hippocampal neurons has been implicated in long-term potentiation, which is thought to be a cellular correlate of learning and memory. |
1998-01-22 |
2023-08-12 |
Not clear |
| M L Ruehr, L Zhang, R V Dorma. Lipid-dependent modulation of Ca2+ availability in isolated mossy fiber nerve endings. Neurochemical research. vol 22. issue 10. 1998-01-22. PMID:9342725. |
the activation of protein kinase c with phorbol esters potentiates the depolarization-evoked release of glutamate from mossy fiber and other hippocampal nerve terminals. |
1998-01-22 |
2023-08-12 |
Not clear |
| E Fedele, A Conti, M Raiter. The glutamate receptor/NO/cyclic GMP pathway in the hippocampus of freely moving rats: modulation by cyclothiazide, interaction with GABA and the behavioural consequences. Neuropharmacology. vol 36. issue 10. 1998-01-22. PMID:9423927. |
the glutamate receptor/no/cyclic gmp pathway in the hippocampus of freely moving rats: modulation by cyclothiazide, interaction with gaba and the behavioural consequences. |
1998-01-22 |
2023-08-12 |
rat |
| E Fedele, A Conti, M Raiter. The glutamate receptor/NO/cyclic GMP pathway in the hippocampus of freely moving rats: modulation by cyclothiazide, interaction with GABA and the behavioural consequences. Neuropharmacology. vol 36. issue 10. 1998-01-22. PMID:9423927. |
the results suggest that (a) ampa/kainate receptors linked to the no/cgmp pathway in the hippocampus (but not nmda receptors) are tonically activated and kept in a desensitized state by endogenous glutamate; (b) blockade of ampa/kainate receptor desensitization by cyclothiazide leads to endogenous activation of nmda receptors; (c) the hippocampal no/cgmp system is under a gabaergic inhibitory tone driven by non-nmda ionotropic receptors; (d) the pre-convulsive episodes observed depend on hippocampal nmda receptor activation but not on no and cgmp production. |
1998-01-22 |
2023-08-12 |
rat |
| E Fedele, G Varnier, M Raiter. In vivo microdialysis study of GABA(A) and GABA(B) receptors modulating the glutamate receptor/NO/cyclic GMP pathway in the rat hippocampus. Neuropharmacology. vol 36. issue 10. 1998-01-22. PMID:9423928. |
in vivo microdialysis study of gaba(a) and gaba(b) receptors modulating the glutamate receptor/no/cyclic gmp pathway in the rat hippocampus. |
1998-01-22 |
2023-08-12 |
rat |
| W Y Ong, V J Balca. Group I metabotropic glutamate receptor agonist causes neurodegeneration in rat hippocampus. Journal fur Hirnforschung. vol 38. issue 3. 1998-01-21. PMID:9350502. |
group i metabotropic glutamate receptor agonist causes neurodegeneration in rat hippocampus. |
1998-01-21 |
2023-08-12 |
rat |
| W Y Ong, V J Balca. Group I metabotropic glutamate receptor agonist causes neurodegeneration in rat hippocampus. Journal fur Hirnforschung. vol 38. issue 3. 1998-01-21. PMID:9350502. |
we now report that intracerebroventricular injections of a group i metabotropic glutamate receptor agonist (s)-3,5-dihydroxyphenylglycine (dhpg) leads, within hours, to changes in the distribution of ionotropic glutamate receptors in the hippocampus and a delayed (4-7 days) loss of hippocampal pyramidal neurons. |
1998-01-21 |
2023-08-12 |
rat |
| A J Owen, S Ijaz, H Miyashita, T Wishart, W Howlett, A Shuai. Zonisamide as a neuroprotective agent in an adult gerbil model of global forebrain ischemia: a histological, in vivo microdialysis and behavioral study. Brain research. vol 770. issue 1-2. 1998-01-21. PMID:9372210. |
in vivo microdialysis was performed on a separate group of animals in order to determine the patterns of ischemia-induced glutamate accumulation in the ca1 sector of the hippocampus. |
1998-01-21 |
2023-08-12 |
human |
| H Katsumori, Y Minabe, M Osawa, C R Ashb. Acute effects of various GABA receptor agonists and glutamate antagonists on focal hippocampal seizures in freely moving rats elicited by low-frequency stimulation. Synapse (New York, N.Y.). vol 28. issue 1. 1998-01-20. PMID:9414023. |
acute effects of various gaba receptor agonists and glutamate antagonists on focal hippocampal seizures in freely moving rats elicited by low-frequency stimulation. |
1998-01-20 |
2023-08-12 |
rat |
| H L Rowley, C A Marsden, K F Marti. Generalised seizure-induced changes in rat hippocampal glutamate but not GABA release are potentiated by repeated seizures. Neuroscience letters. vol 234. issue 2-3. 1998-01-15. PMID:9364518. |
generalised seizure-induced changes in rat hippocampal glutamate but not gaba release are potentiated by repeated seizures. |
1998-01-15 |
2023-08-12 |
rat |
| H L Rowley, C A Marsden, K F Marti. Generalised seizure-induced changes in rat hippocampal glutamate but not GABA release are potentiated by repeated seizures. Neuroscience letters. vol 234. issue 2-3. 1998-01-15. PMID:9364518. |
the effects of repeated or a single generalised seizure on extracellular glutamate and gamma-aminobutyric acid (gaba) levels in the ventral hippocampus of the freely-moving rat were studied using maximal electroshock-induced seizures in conjunction with in vivo microdialysis. |
1998-01-15 |
2023-08-12 |
rat |
| I Smolders, G M Khan, H Lindekens, S Prikken, C A Marvin, J Manil, G Ebinger, Y Michott. Effectiveness of vigabatrin against focally evoked pilocarpine-induced seizures and concomitant changes in extracellular hippocampal and cerebellar glutamate, gamma-aminobutyric acid and dopamine levels, a microdialysis-electrocorticography study in freely moving rats. The Journal of pharmacology and experimental therapeutics. vol 283. issue 3. 1998-01-15. PMID:9399999. |
effectiveness of vigabatrin against focally evoked pilocarpine-induced seizures and concomitant changes in extracellular hippocampal and cerebellar glutamate, gamma-aminobutyric acid and dopamine levels, a microdialysis-electrocorticography study in freely moving rats. |
1998-01-15 |
2023-08-12 |
rat |
| I Smolders, G M Khan, H Lindekens, S Prikken, C A Marvin, J Manil, G Ebinger, Y Michott. Effectiveness of vigabatrin against focally evoked pilocarpine-induced seizures and concomitant changes in extracellular hippocampal and cerebellar glutamate, gamma-aminobutyric acid and dopamine levels, a microdialysis-electrocorticography study in freely moving rats. The Journal of pharmacology and experimental therapeutics. vol 283. issue 3. 1998-01-15. PMID:9399999. |
this study monitored changes in extracellular hippocampal gamma-aminobutyric acid (gaba), glutamate and dopamine levels after systemic (30 mg/kg/day) or local (intrahippocampal or intranigral, 5 mm or 600 microm for 180 min at 2 microl/min) vigabatrin administration, and evaluated the effectiveness of this antiepileptic drug against pilocarpine-induced seizure activity. |
1998-01-15 |
2023-08-12 |
rat |
| I Smolders, G M Khan, H Lindekens, S Prikken, C A Marvin, J Manil, G Ebinger, Y Michott. Effectiveness of vigabatrin against focally evoked pilocarpine-induced seizures and concomitant changes in extracellular hippocampal and cerebellar glutamate, gamma-aminobutyric acid and dopamine levels, a microdialysis-electrocorticography study in freely moving rats. The Journal of pharmacology and experimental therapeutics. vol 283. issue 3. 1998-01-15. PMID:9399999. |
effective protection was reflected in a lack of sustained elevations of hippocampal glutamate levels. |
1998-01-15 |
2023-08-12 |
rat |