| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Furukawa, M P Mattso. Secreted amyloid precursor protein alpha selectively suppresses N-methyl-D-aspartate currents in hippocampal neurons: involvement of cyclic GMP. Neuroscience. vol 83. issue 2. 1998-03-12. PMID:9460751. |
in cultured hippocampal neurons sapp alpha can suppress elevation of [ca2+]i induced by glutamate and can protect neurons against excitotoxicity. |
1998-03-12 |
2023-08-12 |
rat |
| M Reeben, A Laurikainen, J O Hiltunen, E Castrén, M Saarm. The messenger RNAs for both glial cell line-derived neurotrophic factor receptors, c-ret and GDNFRalpha, are induced in the rat brain in response to kainate-induced excitation. Neuroscience. vol 83. issue 1. 1998-03-12. PMID:9466405. |
northern analysis demonstrated that, in the hippocampus, the maximal 2.5-fold increase of c-ret and four-fold increase of gdnfralpha messenger rnas was observed after 12 h of kainate injection, in contrast to gdnf messenger rna, which reaches its maximum in 4-6 h. the blocking of de novo protein synthesis by cycloheximide inhibited the induction of gdnf receptors by kainate, whereas blocking of the n-methyl-d-aspartate-type glutamate receptors by the antagonist dizocilpine maleate did not significantly alter the response. |
1998-03-12 |
2023-08-12 |
human |
| S el Mestikawy, R Wehrlé, J Masson, M C Lombard, M Hamon, C Sotel. Distribution pattern and ultrastructural localization of Rxt1, an orphan Na+/Cl(-)-dependent transporter, in the central nervous system of rats and mice. Neuroscience. vol 77. issue 2. 1998-03-11. PMID:9472393. |
(2) this transporter can be encountered in excitatory axons using glutamate as neurotransmitter (hippocampal and cerebellar mossy fibres: primary afferent fibres), as well as in inhibitory axons known by their gabaergic nature (purkinje cell axon terminals) where it might be involved in the re-uptake process of one or several molecules released from corresponding terminals. |
1998-03-11 |
2023-08-12 |
mouse |
| A Rao, E Kim, M Sheng, A M Crai. Heterogeneity in the molecular composition of excitatory postsynaptic sites during development of hippocampal neurons in culture. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 4. 1998-03-10. PMID:9454832. |
to determine their roles in the assembly of glutamatergic postsynaptic sites, we studied the distributions of nmda- and ampa-type glutamate receptors; the nmda receptor-interacting proteins alpha-actinin-2, psd-95, and chapsyn; and the psd-95-associated protein gkap during the development of hippocampal neurons in culture. |
1998-03-10 |
2023-08-12 |
Not clear |
| K Palm, N Belluardo, M Metsis, T Timmus. Neuronal expression of zinc finger transcription factor REST/NRSF/XBR gene. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 4. 1998-03-10. PMID:9454838. |
the glutamate analog kainic acid increased rest/nrsf/xbr mrna levels in various hippocampal and cortical neurons in vivo, suggesting that rest/nrsf/xbr has a role in neuronal activity-implied processes. |
1998-03-10 |
2023-08-12 |
rat |
| H Schaffhauser, J G Richards, J Cartmell, S Chaboz, J A Kemp, A Klingelschmidt, J Messer, H Stadler, T Woltering, V Mute. In vitro binding characteristics of a new selective group II metabotropic glutamate receptor radioligand, [3H]LY354740, in rat brain. Molecular pharmacology. vol 53. issue 2. 1998-03-10. PMID:9463480. |
the in vitro binding of [3h]ly354740, the first high affinity group ii-selective metabotropic glutamate (mglu) receptor radioligand, was characterized in rat cortical, hippocampal, and thalamic membranes as well as in rat brain sections. |
1998-03-10 |
2023-08-12 |
rat |
| J O Malva, A P Carvalho, C M Carvalh. Kainate receptors in hippocampal CA3 subregion: evidence for a role in regulating neurotransmitter release. Neurochemistry international. vol 32. issue 1. 1998-03-06. PMID:9460695. |
the evidence for the presence of presynaptic kainate receptors in the hippocampus is further substantiated by the demonstration that stimulation of kainate receptors in synaptosomes isolated from the rat hippocampal ca3 subregion increases the intracellular free ca2+ concentration ([ca2+]i) coupled to the release of glutamate. |
1998-03-06 |
2023-08-12 |
rat |
| J O Malva, A F Ambrósio, A P Carvalho, C M Carvalh. Increase of the intracellular Ca2+ concentration mediated by transport of glutamate into rat hippocampal synaptosomes: characterization of the activated voltage sensitive Ca2+ channels. Neurochemistry international. vol 32. issue 1. 1998-03-06. PMID:9460696. |
increase of the intracellular ca2+ concentration mediated by transport of glutamate into rat hippocampal synaptosomes: characterization of the activated voltage sensitive ca2+ channels. |
1998-03-06 |
2023-08-12 |
rat |
| J O Malva, A F Ambrósio, A P Carvalho, C M Carvalh. Increase of the intracellular Ca2+ concentration mediated by transport of glutamate into rat hippocampal synaptosomes: characterization of the activated voltage sensitive Ca2+ channels. Neurochemistry international. vol 32. issue 1. 1998-03-06. PMID:9460696. |
the changes in the intracellular free ca2+ concentration, [ca2+]i, mediated by glutamate and d-aspartate into rat hippocampal synaptosomes was studied. |
1998-03-06 |
2023-08-12 |
rat |
| J O Malva, A F Ambrósio, A P Carvalho, C M Carvalh. Increase of the intracellular Ca2+ concentration mediated by transport of glutamate into rat hippocampal synaptosomes: characterization of the activated voltage sensitive Ca2+ channels. Neurochemistry international. vol 32. issue 1. 1998-03-06. PMID:9460696. |
we clearly identified two different processes by which glutamate increased the [ca2+]i in rat hippocampal synaptosomes: activation of non-nmda receptors and activation of the glutamate transporters. |
1998-03-06 |
2023-08-12 |
rat |
| A I Sacaan, E M Santori, T S Ra. (S)-4-carboxy-3-hydroxyphenylglycine activates phosphatidyl inositol linked metabotropic glutamate receptors in different brain regions of the neonatal rat. Neurochemistry international. vol 32. issue 1. 1998-03-06. PMID:9460705. |
in the present investigation, effects of several agonists and antagonists of metabotropic glutamate receptors (mglurs) which are coupled to phosphatidyl inositol (pi) hydrolysis were evaluated in slices of neonatal rat hippocampus, striatum, cortex and cerebellum. |
1998-03-06 |
2023-08-12 |
rat |
| L K Friedman, E F Sperber, S L Moshé, M V Bennett, R S Zuki. Developmental regulation of glutamate and GABA(A) receptor gene expression in rat hippocampus following kainate-induced status epilepticus. Developmental neuroscience. vol 19. issue 6. 1998-03-05. PMID:9445090. |
developmental regulation of glutamate and gaba(a) receptor gene expression in rat hippocampus following kainate-induced status epilepticus. |
1998-03-05 |
2023-08-12 |
rat |
| L K Friedman, E F Sperber, S L Moshé, M V Bennett, R S Zuki. Developmental regulation of glutamate and GABA(A) receptor gene expression in rat hippocampus following kainate-induced status epilepticus. Developmental neuroscience. vol 19. issue 6. 1998-03-05. PMID:9445090. |
in rat pups resistant to kainate seizure-induced hippocampal neurodegeneration by silver impregnation, glutamate or gaba(a) alpha1-receptor mrnas were unaltered in ca3 neurons 24 h after status epilepticus. |
1998-03-05 |
2023-08-12 |
rat |
| E Grigorenko, S Glazier, W Bell, M Tytell, E Nosel, T Pons, S A Deadwyle. Changes in glutamate receptor subunit composition in hippocampus and cortex in patients with refractory epilepsy. Journal of the neurological sciences. vol 153. issue 1. 1998-03-05. PMID:9455976. |
changes in glutamate receptor subunit composition in hippocampus and cortex in patients with refractory epilepsy. |
1998-03-05 |
2023-08-12 |
human |
| E Grigorenko, S Glazier, W Bell, M Tytell, E Nosel, T Pons, S A Deadwyle. Changes in glutamate receptor subunit composition in hippocampus and cortex in patients with refractory epilepsy. Journal of the neurological sciences. vol 153. issue 1. 1998-03-05. PMID:9455976. |
an assessment of glutamate receptor subunit profiles was made in hippocampus and temporal lobe cortex of patients with refractory epilepsy. |
1998-03-05 |
2023-08-12 |
human |
| E Grigorenko, S Glazier, W Bell, M Tytell, E Nosel, T Pons, S A Deadwyle. Changes in glutamate receptor subunit composition in hippocampus and cortex in patients with refractory epilepsy. Journal of the neurological sciences. vol 153. issue 1. 1998-03-05. PMID:9455976. |
molecular biological analyses using reverse transcription reaction (rt) followed by polymerase chain reaction (pcr) revealed changes in the distribution profile of the transcripts of ampa/ka glutamate receptor subunits in hippocampal and cortical tissue from patients with refractory epilepsy when compared to similar tissue from six human and four non-human primate samples with no history of seizures or seizure medication. |
1998-03-05 |
2023-08-12 |
human |
| S W Weiss, D S Albers, M J Iadarola, T M Dawson, V L Dawson, D G Standaer. NMDAR1 glutamate receptor subunit isoforms in neostriatal, neocortical, and hippocampal nitric oxide synthase neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 5. 1998-03-04. PMID:9464997. |
nmdar1 glutamate receptor subunit isoforms in neostriatal, neocortical, and hippocampal nitric oxide synthase neurons. |
1998-03-04 |
2023-08-12 |
rat |
| W Lasoń, J Turchan, B Przewłocka, D Labuz, R Przewłock. Effects of repeated MK-801 administration on the glutamate receptor gene expression in the rat hippocampus. Polish journal of pharmacology. vol 49. issue 4. 1998-03-02. PMID:9437768. |
effects of repeated mk-801 administration on the glutamate receptor gene expression in the rat hippocampus. |
1998-03-02 |
2023-08-12 |
rat |
| P Saransaari, S S Oja, H D Borkowska, J Koistinaho, W Hilgier, J Albrech. Effects of thioacetamide-induced hepatic failure on the N-methyl-D-aspartate receptor complex in the rat cerebral cortex, striatum, and hippocampus. Binding of different ligands and expression of receptor subunit mRNAs. Molecular and chemical neuropathology. vol 32. issue 1-3. 1998-02-26. PMID:9437666. |
in he rats, bmax of nmda-displaceable glutamate binding was increased in the cerebral cortex and hippocampus, but slightly decreased in the striatum. |
1998-02-26 |
2023-08-12 |
rat |
| C A Tamming. Schizophrenia and glutamatergic transmission. Critical reviews in neurobiology. vol 12. issue 1-2. 1998-02-24. PMID:9444480. |
we propose a "working" glutamate hypothesis of schizophrenia which postulates a diminished glutamatergic transmission in the hippocampal glutamate-mediated efferent pathways and cerebral dysfunction in the hippocampus and its target areas, especially the anterior cingulate cortex. |
1998-02-24 |
2023-08-12 |
human |