| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ana Paula Thomazi, Graça F R S Godinho, Juliana M Rodrigues, Fábio D Schwalm, Marcos E S Frizzo, Emílio Moriguchi, Diogo O Souza, Susana T Wofchu. Ontogenetic profile of glutamate uptake in brain structures slices from rats: sensitivity to guanosine. Mechanisms of ageing and development. vol 125. issue 7. 2005-03-02. PMID:15246742. |
in the present study, we used slices of striatum, hippocampus and cortex from rat brain to describe the in vitro profile of glutamate uptake during development and ageing, and its sensitivity to guanosine. |
2005-03-02 |
2023-08-12 |
rat |
| Ana Paula Thomazi, Graça F R S Godinho, Juliana M Rodrigues, Fábio D Schwalm, Marcos E S Frizzo, Emílio Moriguchi, Diogo O Souza, Susana T Wofchu. Ontogenetic profile of glutamate uptake in brain structures slices from rats: sensitivity to guanosine. Mechanisms of ageing and development. vol 125. issue 7. 2005-03-02. PMID:15246742. |
there was a maximum decrease in glutamate uptake in striatum and hippocampus in 15-month-old rats, which later increased, while in cortex there was a significant decrease in rats aged 60 days old. |
2005-03-02 |
2023-08-12 |
rat |
| Peter Kugler, Verena Schleye. Developmental expression of glutamate transporters and glutamate dehydrogenase in astrocytes of the postnatal rat hippocampus. Hippocampus. vol 14. issue 8. 2005-03-02. PMID:15390174. |
developmental expression of glutamate transporters and glutamate dehydrogenase in astrocytes of the postnatal rat hippocampus. |
2005-03-02 |
2023-08-12 |
rat |
| Peter Kugler, Verena Schleye. Developmental expression of glutamate transporters and glutamate dehydrogenase in astrocytes of the postnatal rat hippocampus. Hippocampus. vol 14. issue 8. 2005-03-02. PMID:15390174. |
in the present study, we have used nonradioactive in situ hybridization, immunocytochemistry, and immunoblotting to show the cellular and regional expression of the high-affinity glutamate transporters glast (eaat1) and generic glt1 (eaat2; glial form of glt1) in the rat hippocampus during postnatal development (p1-60). |
2005-03-02 |
2023-08-12 |
rat |
| Peter Kugler, Verena Schleye. Developmental expression of glutamate transporters and glutamate dehydrogenase in astrocytes of the postnatal rat hippocampus. Hippocampus. vol 14. issue 8. 2005-03-02. PMID:15390174. |
these observations suggest that the extent of glutamate transporter expression and of glutamate-metabolizing gdh activity in astrocytes is intimately correlated with the formation of glutamatergic synapses in the developing hippocampus. |
2005-03-02 |
2023-08-12 |
rat |
| Brady J Maher, Roger L Mackinnon, Jihong Bai, Edwin R Chapman, Paul T Kell. Activation of postsynaptic Ca(2+) stores modulates glutamate receptor cycling in hippocampal neurons. Journal of neurophysiology. vol 93. issue 1. 2005-02-28. PMID:15604462. |
activation of postsynaptic ca(2+) stores modulates glutamate receptor cycling in hippocampal neurons. |
2005-02-28 |
2023-08-12 |
Not clear |
| H Manev, T Uz, T Q. Early upregulation of hippocampal 5-lipoxygenase following systemic administration of kainate to rats. Restorative neurology and neuroscience. vol 12. issue 2-3. 2005-02-22. PMID:12671301. |
increased formation of leukotrienes was found in the hippocampus of rats in which seizures were induced by a glutamate receptor agonist, kainate. |
2005-02-22 |
2023-08-12 |
rat |
| Qun Wang, Sue Yu, Agnes Simonyi, George Rottinghaus, Grace Y Sun, Albert Y Su. Resveratrol protects against neurotoxicity induced by kainic acid. Neurochemical research. vol 29. issue 11. 2005-02-22. PMID:15662844. |
increased oxidative stress has been implicated in the mechanisms of excitotoxicity in hippocampus induced by kainic acid (ka), an excitatory glutamate receptor agonist. |
2005-02-22 |
2023-08-12 |
rat |
| A V Sergutina, L M Gershteĭ. [Morphochemical analysis of hippocampus of rats predisposed (August) or resistant (Wistar) to emotional stress]. Morfologiia (Saint Petersburg, Russia). vol 125. issue 2. 2005-02-18. PMID:15232864. |
using quantitative cytochemical methods it was demonstrated that the activities of aminopeptidase, monoaminooxidase (substrates--tryptamine and serotonin), and glutamate dehydrogenase, were lower in the hippocampus of august rats (predisposed to emotional stress) as compared to that one in wistar rats (resistant to emotional stress). |
2005-02-18 |
2023-08-12 |
rat |
| Andrey M Mazarat. Galanin and galanin receptors in epilepsy. Neuropeptides. vol 38. issue 6. 2005-02-18. PMID:15567469. |
galanin, a 29-amino acid residues neuropeptide which inhibits glutamate release in the hippocampus, is a likely member of the anticonvulsant peptide family. |
2005-02-18 |
2023-08-12 |
Not clear |
| Jens Noraber. Organotypic brain slice cultures: an efficient and reliable method for neurotoxicological screening and mechanistic studies. Alternatives to laboratory animals : ATLA. vol 32. issue 4. 2005-02-18. PMID:15651916. |
for the evaluation of the slice culture method, organotypic hippocampal slice cultures were exposed to toxic doses of the excitotoxins, glutamate, n-methyl-d-aspartate (nmda), kainic acid and 2-amino-3-hydroxy-5-methyl-4-isoxazole propionate (ampa), and the glial toxin, dl-alpha-aminoadipic acid (dlaaa). |
2005-02-18 |
2023-08-12 |
Not clear |
| Elaine Coleman, Robert Judd, Lori Hoe, John Dennis, Philip Posne. Effects of diabetes mellitus on astrocyte GFAP and glutamate transporters in the CNS. Glia. vol 48. issue 2. 2005-02-15. PMID:15378652. |
we examined the effects of streptozotocin (stz)-induced diabetes in rats on the level of the astrocyte intermediate filament protein, glial fibrillary acidic protein (gfap), number of astrocytes, and levels of the astrocyte glutamate transporters, glutamate transporter-1 (glt-1) and glutamate/aspartate transporter (glast), in the cerebral cortex, hippocampus, and cerebellum by western blotting (wb) and immunohistochemistry (ih). |
2005-02-15 |
2023-08-12 |
rat |
| Elaine Coleman, Robert Judd, Lori Hoe, John Dennis, Philip Posne. Effects of diabetes mellitus on astrocyte GFAP and glutamate transporters in the CNS. Glia. vol 48. issue 2. 2005-02-15. PMID:15378652. |
no significant differences were noted in astrocyte glutamate transporter levels in the cerebral cortex, hippocampus, or cerebellum at either time period (wb, ih). |
2005-02-15 |
2023-08-12 |
rat |
| Laura Maggi, Elisabetta Sola, Federico Minneci, Corentin Le Magueresse, Jean Pierre Changeux, Enrico Cherubin. Persistent decrease in synaptic efficacy induced by nicotine at Schaffer collateral-CA1 synapses in the immature rat hippocampus. The Journal of physiology. vol 559. issue Pt 3. 2005-02-11. PMID:15272042. |
in previous work on the immature hippocampus we have shown that, at low probability (p) synapses, activation of alpha7 nachrs by nicotine or by endogenously released acetylcholine persistently enhanced glutamate release and converted 'presynaptically silent' synapses into functional ones. |
2005-02-11 |
2023-08-12 |
rat |
| Atsushi Taked. [Function and toxicity of trace metals in the central nervous system]. Clinical calcium. vol 14. issue 8. 2005-02-09. PMID:15577096. |
zinc released into the synaptic cleft may serve as an inhibitory neuromodulator of glutamate release in the hippocampus, while neuromodulation by other trace metals such as manganese and copper might mean both functional and toxic aspects in the synapse. |
2005-02-09 |
2023-08-12 |
Not clear |
| Atsushi Taked. [Function and toxicity of trace metals in the central nervous system]. Clinical calcium. vol 14. issue 8. 2005-02-09. PMID:15577096. |
dietary zinc deficiency affects zinc homeostasis in the brain, followed by an enhanced susceptibility to excitotoxicity of glutamate in the hippocampus. |
2005-02-09 |
2023-08-12 |
Not clear |
| K Ono, N Iwatsuki, T Tajima, M Takahashi, Y Hashimot. Elevation of the extracellular glutamate concentration in the hippocampus after total cerebral ischemia related to the deterioration of the recovery in EEG and evoked potentials in dogs. Journal of anesthesia. vol 7. issue 3. 2005-02-08. PMID:15278820. |
elevation of the extracellular glutamate concentration in the hippocampus after total cerebral ischemia related to the deterioration of the recovery in eeg and evoked potentials in dogs. |
2005-02-08 |
2023-08-12 |
Not clear |
| K Ono, N Iwatsuki, T Tajima, M Takahashi, Y Hashimot. Elevation of the extracellular glutamate concentration in the hippocampus after total cerebral ischemia related to the deterioration of the recovery in EEG and evoked potentials in dogs. Journal of anesthesia. vol 7. issue 3. 2005-02-08. PMID:15278820. |
the concentrations of extracellular glutamate (glu), aspartate (asp) and glycine (gly) were measured by microdialysis method in the cortex and hippocampus before, during and after 15 min of total cerebral ischemia in dogs. |
2005-02-08 |
2023-08-12 |
Not clear |
| María Cecilia Angulo, Andreï S Kozlov, Serge Charpak, Etienne Audina. Glutamate released from glial cells synchronizes neuronal activity in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 31. 2005-02-07. PMID:15295027. |
glutamate released from glial cells synchronizes neuronal activity in the hippocampus. |
2005-02-07 |
2023-08-12 |
rat |
| María Cecilia Angulo, Andreï S Kozlov, Serge Charpak, Etienne Audina. Glutamate released from glial cells synchronizes neuronal activity in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 31. 2005-02-07. PMID:15295027. |
we demonstrate here in hippocampal slices of 2- to 5-week-old rats that glutamate released from glial cells generates slow transient currents (stcs) mediated by the activation of nmda receptors in pyramidal cells. |
2005-02-07 |
2023-08-12 |
rat |