| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Simone Molz, Helena Decker, Ivaldo J L Oliveira, Diogo O Souza, Carla I Tasc. Neurotoxicity induced by glutamate in glucose-deprived rat hippocampal slices is prevented by GMP. Neurochemical research. vol 30. issue 1. 2005-04-08. PMID:15756936. |
neurotoxicity induced by glutamate in glucose-deprived rat hippocampal slices is prevented by gmp. |
2005-04-08 |
2023-08-12 |
rat |
| Simone Molz, Helena Decker, Ivaldo J L Oliveira, Diogo O Souza, Carla I Tasc. Neurotoxicity induced by glutamate in glucose-deprived rat hippocampal slices is prevented by GMP. Neurochemical research. vol 30. issue 1. 2005-04-08. PMID:15756936. |
guanosine-5'-monophosphate (gmp) was evaluated as a neuroprotective agent against the damage induced by glutamate in rat hippocampal slices submitted to glucose deprivation. |
2005-04-08 |
2023-08-12 |
rat |
| Nozomu H Nakamura, Daniel R Rosell, Keith T Akama, Bruce S McEwe. Estrogen and ovariectomy regulate mRNA and protein of glutamic acid decarboxylases and cation-chloride cotransporters in the adult rat hippocampus. Neuroendocrinology. vol 80. issue 5. 2005-04-01. PMID:15677881. |
we therefore studied the estrogenic regulation of two glutamate decarboxylase (gad) isoforms, gad65 and gad67, as well as nkcc1 and kcc2 in the adult female rat hippocampus by immunohistochemistry and in situ hybridization. |
2005-04-01 |
2023-08-12 |
rat |
| Diana Cunha-Reis, Ana M Sebastião, Kerstin Wirkner, Peter Illes, Joaquim Alexandre Ribeir. VIP enhances both pre- and postsynaptic GABAergic transmission to hippocampal interneurones leading to increased excitatory synaptic transmission to CA1 pyramidal cells. British journal of pharmacology. vol 143. issue 6. 2005-03-29. PMID:15504757. |
vip (0.1-100 nm) increased [(3)h]gaba release from hippocampal synaptosomes (maximum effect at 1 nm vip; 63.8 +/- 4.0%) but did not change [(3)h]glutamate release. |
2005-03-29 |
2023-08-12 |
Not clear |
| K Ohtaki, K Matsubara, S Fujimaru, K Shimizu, T Awaya, M Suno, K Chiba, N Hayase, H Shion. Cefoselis, a beta-lactam antibiotic, easily penetrates the blood-brain barrier and causes seizure independently by glutamate release. Journal of neural transmission (Vienna, Austria : 1996). vol 111. issue 12. 2005-03-23. PMID:15565489. |
a local administration of cefoselis into the hippocampus through the microdialysis probe caused a striking elevation of extracellular glutamate, with a minimum increase in gamma-aminobutyric acid (gaba). |
2005-03-23 |
2023-08-12 |
rat |
| K Ohtaki, K Matsubara, S Fujimaru, K Shimizu, T Awaya, M Suno, K Chiba, N Hayase, H Shion. Cefoselis, a beta-lactam antibiotic, easily penetrates the blood-brain barrier and causes seizure independently by glutamate release. Journal of neural transmission (Vienna, Austria : 1996). vol 111. issue 12. 2005-03-23. PMID:15565489. |
however, a systematic cefoselis administration via the tail vein did not elevate extracellular glutamate and gaba concentrations in the hippocampus of renal failure rats that exhibited marked seizures. |
2005-03-23 |
2023-08-12 |
rat |
| Idil Cavus, Willard S Kasoff, Michael P Cassaday, Ralph Jacob, Ralitza Gueorguieva, Robert S Sherwin, John H Krystal, Dennis D Spencer, Walid M Abi-Saa. Extracellular metabolites in the cortex and hippocampus of epileptic patients. Annals of neurology. vol 57. issue 2. 2005-03-23. PMID:15668975. |
we used the zero-flow microdialysis method to measure the extracellular levels of glutamate, glutamine, and the major energy substrates glucose and lactate in the epileptogenic and the nonepileptogenic cortex and hippocampus of 38 awake epileptic patients during the interictal period. |
2005-03-23 |
2023-08-12 |
Not clear |
| Idil Cavus, Willard S Kasoff, Michael P Cassaday, Ralph Jacob, Ralitza Gueorguieva, Robert S Sherwin, John H Krystal, Dennis D Spencer, Walid M Abi-Saa. Extracellular metabolites in the cortex and hippocampus of epileptic patients. Annals of neurology. vol 57. issue 2. 2005-03-23. PMID:15668975. |
the epileptogenic hippocampus had surprisingly high basal glutamate levels, low glutamine/glutamate ratio, high lactate levels, and indication for poor glucose utilization. |
2005-03-23 |
2023-08-12 |
Not clear |
| Idil Cavus, Willard S Kasoff, Michael P Cassaday, Ralph Jacob, Ralitza Gueorguieva, Robert S Sherwin, John H Krystal, Dennis D Spencer, Walid M Abi-Saa. Extracellular metabolites in the cortex and hippocampus of epileptic patients. Annals of neurology. vol 57. issue 2. 2005-03-23. PMID:15668975. |
we propose that interictal energetic deficiency in the epileptogenic hippocampus could contribute to impaired glutamate reuptake and glutamate-glutamine cycling, resulting in persistently increased extracellular glutamate, glial and neuronal toxicity, increased lactate production together with poor lactate and glucose utilization, and ultimately worsening energy metabolism. |
2005-03-23 |
2023-08-12 |
Not clear |
| S Yamamoto, T Kanno, T Nagata, T Yaguchi, A Tanaka, T Nishizak. The linoleic acid derivative FR236924 facilitates hippocampal synaptic transmission by enhancing activity of presynaptic alpha7 acetylcholine receptors on the glutamatergic terminals. Neuroscience. vol 130. issue 1. 2005-03-22. PMID:15561436. |
fr236924 stimulated glutamate release from rat hippocampal slices and in the hippocampus of freely behaving rats, and the effect was also inhibited by gf109203x or alpha-bungarotoxin. |
2005-03-22 |
2023-08-12 |
rat |
| S Yamamoto, T Kanno, T Nagata, T Yaguchi, A Tanaka, T Nishizak. The linoleic acid derivative FR236924 facilitates hippocampal synaptic transmission by enhancing activity of presynaptic alpha7 acetylcholine receptors on the glutamatergic terminals. Neuroscience. vol 130. issue 1. 2005-03-22. PMID:15561436. |
it is concluded from these results that fr236924 stimulates glutamate release by functionally targeting presynaptic alpha7 ach receptors on the glutamatergic terminals under the influence of pkc, responsible for the facilitatory action on hippocampal synaptic transmission. |
2005-03-22 |
2023-08-12 |
rat |
| Enrico Anlauf, Amin Derouich. Astrocytic exocytosis vesicles and glutamate: a high-resolution immunofluorescence study. Glia. vol 49. issue 1. 2005-03-21. PMID:15390103. |
also, glutamate released from astrocytes in the hippocampal slice interferes with synaptic neurotransmission. |
2005-03-21 |
2023-08-12 |
Not clear |
| Stefan Kahlert, Gregor Zündorf, Georg Reise. Glutamate-mediated influx of extracellular Ca2+ is coupled with reactive oxygen species generation in cultured hippocampal neurons but not in astrocytes. Journal of neuroscience research. vol 79. issue 1-2. 2005-03-18. PMID:15578732. |
we studied regulation of ca2+ level, mitochondrial potential, and ros generation in defined mixed hippocampal cell cultures exposed to glutamate (100 microm). |
2005-03-18 |
2023-08-12 |
Not clear |
| A Müldner, S Hoye. Delayed decrease of excitatory amino acid neurotransmitters in parietotemporal cortex and hippocampus after complete cerebral ischemia in aged rats. Archives of gerontology and geriatrics. vol 24. issue 1. 2005-03-14. PMID:15374133. |
a 15-min period of complete cerebral ischemia (cci) was used in aged rats to investigate changes in tissue contents of the amino acid neurotransmitters (aant) glutamate (glu), aspartate (asp), gamma aminobutyric acid (gaba) and glycine (gly) in parietotemporal cortex and hippocampus during ischemia and up to 96 h of postischemic recirculation. |
2005-03-14 |
2023-08-12 |
rat |
| R A Floyd, J M Carne. Age influence on oxidative events during brain ischemia/reperfusion. Archives of gerontology and geriatrics. vol 12. issue 2-3. 2005-03-10. PMID:15374445. |
the loss of glutamine synthetase activity may possibly lead to the build-up of glutamate, an excitotoxic amino acid which has been strongly implicated in the neuronal death observed in hippocampus following an iri. |
2005-03-10 |
2023-08-12 |
Not clear |
| E Bronzetti, L Felici, F Ament. Age-related changes of glutamate dehydrogenase in the rat hippocampus: an enzyme histochemical study. Archives of gerontology and geriatrics. vol 10. issue 3. 2005-03-08. PMID:15374497. |
age-related changes of glutamate dehydrogenase in the rat hippocampus: an enzyme histochemical study. |
2005-03-08 |
2023-08-12 |
rat |
| E Bronzetti, L Felici, F Ament. Age-related changes of glutamate dehydrogenase in the rat hippocampus: an enzyme histochemical study. Archives of gerontology and geriatrics. vol 10. issue 3. 2005-03-08. PMID:15374497. |
enzyme histochemical techniques associated with microphotometry were used to evaluate the reactivity of glutamate dehydrogenase (gdh) in the hippocampus of young (3 month) adult (12 month) and old (26 month) male sprague-dawley rats. |
2005-03-08 |
2023-08-12 |
rat |
| E Bronzetti, L Felici, F Ament. Age-related changes of glutamate dehydrogenase in the rat hippocampus: an enzyme histochemical study. Archives of gerontology and geriatrics. vol 10. issue 3. 2005-03-08. PMID:15374497. |
the hippocampus is known to be involved in the acquisition of two-way avoidance learning and is thought to utilize glutamate as one of its main neurotransmitters. |
2005-03-08 |
2023-08-12 |
rat |
| E Bronzetti, L Felici, F Ament. Age-related changes of glutamate dehydrogenase in the rat hippocampus: an enzyme histochemical study. Archives of gerontology and geriatrics. vol 10. issue 3. 2005-03-08. PMID:15374497. |
moreover, the possibility that a decreased glutamate catabolism occurring in old rats may contribute to the neuronal loss described in the hippocampus of aged rats is discussed. |
2005-03-08 |
2023-08-12 |
rat |
| P Maciejak, A I Członkowska, A Bidziński, J Walkowiak, J Szyndler, M Lehner, A Skórzewska, D Turzyńska, M Zienowicz, A Wisłowska, E Taracha, P Krzaścik, A Płaźni. Pregnenolone sulfate potentiates the effects of NMDA on hippocampal alanine and dopamine. Pharmacology, biochemistry, and behavior. vol 78. issue 4. 2005-03-04. PMID:15301935. |
these and other data indicate that the enhancement by ps of hippocampal levels of alanine may contribute to the seizures development as this amino acid is a precursor of glutamate, and a co-agonist of the nmda receptors. |
2005-03-04 |
2023-08-12 |
mouse |