| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shukuko Yoshida, Satoshi Yamamura, Keiko Ohoyama, Masanori Nakagawa, Eishi Motomura, Sunao Kaneko, Motohiro Okad. Effects of valproate on neurotransmission associated with ryanodine receptors. Neuroscience research. vol 68. issue 4. 2011-03-02. PMID:20832432. |
perfusion with ryanodine increased the hippocampal extracellular level of glutamate (ryanodine concentration range: 1-1000μm) concentration-dependently; however, that of gaba was increased by 1-100μm ryanodine concentration-dependently but the stimulatory effects of 1000μm ryanodine on gaba release was not observed. |
2011-03-02 |
2023-08-12 |
rat |
| Shukuko Yoshida, Satoshi Yamamura, Keiko Ohoyama, Masanori Nakagawa, Eishi Motomura, Sunao Kaneko, Motohiro Okad. Effects of valproate on neurotransmission associated with ryanodine receptors. Neuroscience research. vol 68. issue 4. 2011-03-02. PMID:20832432. |
both acute and sub-acute administrations of therapeutic-relevant vpa inhibited ryanodine-induced responses of hippocampal extracellular glutamate level without affecting that of gaba. |
2011-03-02 |
2023-08-12 |
rat |
| Byron K Y Bitanihirwe, Daria Peleg-Raibstein, Forouhar Mouttet, Joram Feldon, Urs Meye. Late prenatal immune activation in mice leads to behavioral and neurochemical abnormalities relevant to the negative symptoms of schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 12. 2011-02-16. PMID:20736993. |
prenatal immune activation in late gestation also led to numerous, partly sex-specific changes in basal neurotransmitter levels, including reduced dopamine (da) and glutamate contents in the prefrontal cortex and hippocampus, as well as reduced γ-aminobutyric acid (gaba) and glycine contents in the hippocampus and prefrontal cortex, respectively. |
2011-02-16 |
2023-08-12 |
mouse |
| Yo Shinoda, Tetsushi Sadakata, Kazuhito Nakao, Ritsuko Katoh-Semba, Emi Kinameri, Asako Furuya, Yuchio Yanagawa, Hajime Hirase, Teiichi Furuich. Calcium-dependent activator protein for secretion 2 (CAPS2) promotes BDNF secretion and is critical for the development of GABAergic interneuron network. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 1. 2011-02-10. PMID:21173225. |
moreover, caps2-ko mice exhibited several gaba system-associated deficits, including reduced late-phase long-term potentiation at ca3-ca1 synapses, decreased hippocampal theta oscillation frequency, and increased anxiety-like behavior. |
2011-02-10 |
2023-08-12 |
mouse |
| Armen M Abramian, Eydith Comenencia-Ortiz, Mansi Vithlani, Eva Verena Tretter, Werner Sieghart, Paul A Davies, Stephen J Mos. Protein kinase C phosphorylation regulates membrane insertion of GABAA receptor subtypes that mediate tonic inhibition. The Journal of biological chemistry. vol 285. issue 53. 2011-02-09. PMID:20940303. |
in the dentate gyrus region of the hippocampus, tonic inhibition is mediated primarily by gaba(a)r subtypes assembled from α4β2/3 with or without the δ subunit. |
2011-02-09 |
2023-08-12 |
human |
| Yi-qiao Li, Hao-hao Chen, Yi-fei Yin, Fei Han, Xue-song Ye, Shu-cai Lin. [Formaldehyde inhalation may damage olfactory bulb and hippocampus in rats]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. vol 39. issue 3. 2011-02-03. PMID:20544989. |
to investigate the effects of formaldehyde inhalation on the morphological damage, and glu, gaba and nos contents in olfactory bulb and hippocampus of rats. |
2011-02-03 |
2023-08-12 |
rat |
| Geert J Schenk, Barbera Veldhuisen, Olga Wedemeier, Caroline C McGown, Theo G Schouten, Melly Oitzl, E Ron de Kloet, Erno Vreugdenhi. Over-expression of δC-DCLK-short in mouse brain results in a more anxious behavioral phenotype. Physiology & behavior. vol 101. issue 4. 2011-01-28. PMID:20705078. |
previously, we have performed an extensive molecular characterization of these transgenic δc-dclk-short mice and established that a specific subunit of the gaba(a) receptor, which is involved in anxiety-related gabaergic neurotransmission, is down-regulated in the hippocampus. |
2011-01-28 |
2023-08-12 |
mouse |
| Joy Y Sebe, Elizabeth C Looke-Stewart, Rosanne C Estrada, Scott C Baraba. Robust tonic GABA currents can inhibit cell firing in mouse newborn neocortical pyramidal cells. The European journal of neuroscience. vol 32. issue 8. 2011-01-28. PMID:20846324. |
within the hippocampus and neocortex, gaba is considered to be excitatory in early development due to a relatively depolarized cl(-) reversal potential (e(cl)). |
2011-01-28 |
2023-08-12 |
mouse |
| Priscila Gubert, Daiana Silva Avila, Jessika Cristina Bridi, Sara Saurin, Thiago Henrique Lugokenski, Jardel Gomes Villarinho, Roselei Fachinetto, Maria Ester Pereira, Juliano Ferreira, João Batista Teixeira da Rocha, Félix Alexandre Antunes Soare. Low concentrations of methamidophos do not alter AChE activity but modulate neurotransmitters uptake in hippocampus and striatum in vitro. Life sciences. vol 88. issue 1-2. 2011-01-21. PMID:21075126. |
as the mechanism of its neurotoxic effects is not well understood, the aim of the present study was to evaluate the effects of meth on glutamate and gamma aminobutyric acid (gaba) uptake and correlate with cell viability and ache and na(+)/k(+)-atpase enzyme activities in striatum and hippocampus slices exposed to low concentrations (0.05 to 1.0 μm) of meth. |
2011-01-21 |
2023-08-12 |
Not clear |
| Hui-Chul Choi, Yeong-In Kim, Hong-Ki Song, Ji-Eun Kim, Duk-Soo Kim, Tae-Cheon Kan. Effects of selective serotonin reuptake inhibitors on GABAergic inhibition in the hippocampus of normal and pilocarpine induced epileptic rats. Brain research. vol 1357. 2011-01-14. PMID:20707986. |
we investigated the effects of fluoxetine, paroxetine and citalopram on the gabaergic transmission in the normal and pilocarpine-induced epileptic rat hippocampus using electroencephalogram (eeg), paired-pulse inhibition (ppi) and vesicular gaba transporter (vgat) immunoreactivity. |
2011-01-14 |
2023-08-12 |
rat |
| Karthik Rajasekaran, Suchitra Joshi, Chengsan Sun, Zakaria Mtchedlishvilli, Jaideep Kapu. Receptors with low affinity for neurosteroids and GABA contribute to tonic inhibition of granule cells in epileptic animals. Neurobiology of disease. vol 40. issue 2. 2011-01-12. PMID:20682339. |
neurosteroid sensitivity of gaba(a) receptor mediated inhibition of the hippocampal dentate granule cells (dgcs) is reduced in animal models of temporal lobe epilepsy. |
2011-01-12 |
2023-08-12 |
Not clear |
| A Amritraj, G Rauw, G B Baker, S Ka. Leu27 insulin-like growth factor-II, an insulin-like growth factor-II analog, attenuates depolarization-evoked GABA release from adult rat hippocampal and cortical slices. Neuroscience. vol 170. issue 3. 2011-01-11. PMID:20659530. |
leu27 insulin-like growth factor-ii, an insulin-like growth factor-ii analog, attenuates depolarization-evoked gaba release from adult rat hippocampal and cortical slices. |
2011-01-11 |
2023-08-12 |
rat |
| A Amritraj, G Rauw, G B Baker, S Ka. Leu27 insulin-like growth factor-II, an insulin-like growth factor-II analog, attenuates depolarization-evoked GABA release from adult rat hippocampal and cortical slices. Neuroscience. vol 170. issue 3. 2011-01-11. PMID:20659530. |
interestingly, the effect is found to be sensitive to pertussis toxin (ptx), indicating the possible involvement of a gi/o protein-dependent pathway in mediating the release of gaba from the hippocampal slices. |
2011-01-11 |
2023-08-12 |
rat |
| Benjamin Förstera, Abdel Ali Belaidi, René Jüttner, Carola Bernert, Michael Tsokos, Thomas-N Lehmann, Peter Horn, Christoph Dehnicke, Günter Schwarz, Jochen C Meie. Irregular RNA splicing curtails postsynaptic gephyrin in the cornu ammonis of patients with epilepsy. Brain : a journal of neurology. vol 133. issue Pt 12. 2011-01-07. PMID:21071388. |
identified temporal lobe epilepsy gephyrins have oligomerization deficits and they curtail hippocampal postsynaptic gephyrin and gaba(a) receptor α2 while interacting with regularly spliced gephyrins. |
2011-01-07 |
2023-08-12 |
Not clear |
| Benjamin Förstera, Abdel Ali Belaidi, René Jüttner, Carola Bernert, Michael Tsokos, Thomas-N Lehmann, Peter Horn, Christoph Dehnicke, Günter Schwarz, Jochen C Meie. Irregular RNA splicing curtails postsynaptic gephyrin in the cornu ammonis of patients with epilepsy. Brain : a journal of neurology. vol 133. issue Pt 12. 2011-01-07. PMID:21071388. |
cellular stress such as alkalosis, for example arising from seizure activity, could thus facilitate the development of temporal lobe epilepsy by reducing gaba(a) receptor α2-mediated hippocampal synaptic transmission selectively in the cornu ammonis. |
2011-01-07 |
2023-08-12 |
Not clear |
| Mélanie Langlois, Pierre-Olivier Polack, Hélène Bernard, Olivier David, Stéphane Charpier, Antoine Depaulis, Colin Deransar. Involvement of the thalamic parafascicular nucleus in mesial temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 49. 2011-01-07. PMID:21147992. |
nmda antagonist and gaba(a) agonist suppressed hippocampal discharges in a dose-dependent way, whereas nmda agonist and gaba(a) antagonist increased hpds. |
2011-01-07 |
2023-08-12 |
mouse |
| Ralph Clinckers, Tine Zgavc, Katia Vermoesen, Alfred Meurs, Yvette Michotte, Ilse Smolder. Pharmacological and neurochemical characterization of the involvement of hippocampal adrenoreceptor subtypes in the modulation of acute limbic seizures. Journal of neurochemistry. vol 115. issue 6. 2011-01-04. PMID:20969569. |
the noradrenaline reuptake inhibitor maprotiline mediated anticonvulsant effects, associated with dose-dependent increases in extracellular hippocampal noradrenaline, dopamine and gaba levels. |
2011-01-04 |
2023-08-12 |
Not clear |
| Ralph Clinckers, Tine Zgavc, Katia Vermoesen, Alfred Meurs, Yvette Michotte, Ilse Smolder. Pharmacological and neurochemical characterization of the involvement of hippocampal adrenoreceptor subtypes in the modulation of acute limbic seizures. Journal of neurochemistry. vol 115. issue 6. 2011-01-04. PMID:20969569. |
interestingly, α(1a) -receptor stimulation and α(1d) -antagonism alone also inhibited seizures associated with respectively significant hippocampal gaba increases and glutamate decreases. |
2011-01-04 |
2023-08-12 |
Not clear |
| Torun Melø, Paolo Bigini, Ursula Sonnewald, Silvia Balosso, Alfredo Cagnotto, Sara Barbera, Sarah Uboldi, Annamaria Vezzani, Tiziana Mennin. Neuronal hyperexcitability and seizures are associated with changes in glial-neuronal interactions in the hippocampus of a mouse model of epilepsy with mental retardation. Journal of neurochemistry. vol 115. issue 6. 2011-01-04. PMID:21044073. |
however, ex vivo(13) c magnetic resonance spectroscopy, after simultaneous injection of [1-(13) c]glucose and [1,2-(13) c]acetate, followed by decapitation, showed decreased [1,2-(13) c]gaba formation from hippocampal astrocytic precursors and a marked reduction in [4,5-(13) c]glutamate derived from glutamine. |
2011-01-04 |
2023-08-12 |
mouse |
| Eva Ruusuvuori, Ilya Kirilkin, Nikhil Pandya, Kai Kail. Spontaneous network events driven by depolarizing GABA action in neonatal hippocampal slices are not attributable to deficient mitochondrial energy metabolism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 46. 2010-12-23. PMID:21084619. |
spontaneous network events driven by depolarizing gaba action in neonatal hippocampal slices are not attributable to deficient mitochondrial energy metabolism. |
2010-12-23 |
2023-08-12 |
rat |