| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Kang, I Spigelman, D W Sapp, R W Olse. Persistent reduction of GABA(A) receptor-mediated inhibition in rat hippocampus after chronic intermittent ethanol treatment. Brain research. vol 709. issue 2. 1997-05-01. PMID:8833758. |
efflux of 36cl-, evoked by application of muscimol, a measure of gaba(a) receptor function, was examined in 300 mu m slices obtained from frontal, parietal, and temporal cortex, hippocampus, and inferior colliculus, one day after the last administration of ethanol. |
1997-05-01 |
2023-08-12 |
rat |
| T Ono, Y Fueta, N A Janjua, O Ohmori, K Ohno, Y Murai, T Mit. Granule cell disinhibition in dentate gyrus of genetically seizure susceptible El mice. Brain research. vol 745. issue 1-2. 1997-04-29. PMID:9037406. |
gaba concentration in the hippocampus was also quantified using hplc. |
1997-04-29 |
2023-08-12 |
mouse |
| M E Hasselmo, B P Wyble, G V Wallenstei. Encoding and retrieval of episodic memories: role of cholinergic and GABAergic modulation in the hippocampus. Hippocampus. vol 6. issue 6. 1997-04-28. PMID:9034856. |
this research focuses on linking episodic memory function to the cellular physiology of hippocampal neurons, with a particular emphasis on modulatory effects at cholinergic and gamma-aminobutyric acid b receptors. |
1997-04-28 |
2023-08-12 |
human |
| H L Wang, A Li, T W. Vasoactive intestinal polypeptide enhances the GABAergic synaptic transmission in cultured hippocampal neurons. Brain research. vol 746. issue 1-2. 1997-04-28. PMID:9037509. |
the whole-cell mode of patch-clamp techniques was used to investigate the effect of vasoactive intestinal polypeptide (vip) on spontaneous gamma-aminobutyric acid (gaba)-mediated inhibitory postsynaptic currents (ipscs) of cultured hippocampal neurons. |
1997-04-28 |
2023-08-12 |
Not clear |
| H L Wang, A Li, T W. Vasoactive intestinal polypeptide enhances the GABAergic synaptic transmission in cultured hippocampal neurons. Brain research. vol 746. issue 1-2. 1997-04-28. PMID:9037509. |
these results suggest that the activation of presynaptic vip receptor enhances the gabaergic synaptic transmission in cultured hippocampal neurons through the camp-pka pathway and that vip is likely to increase gaba release by directly stimulating the vesicular release apparatus. |
1997-04-28 |
2023-08-12 |
Not clear |
| J C Poncer, R A McKinney, B H Gähwiler, S M Thompso. Either N- or P-type calcium channels mediate GABA release at distinct hippocampal inhibitory synapses. Neuron. vol 18. issue 3. 1997-04-24. PMID:9115739. |
either n- or p-type calcium channels mediate gaba release at distinct hippocampal inhibitory synapses. |
1997-04-24 |
2023-08-12 |
Not clear |
| J C Poncer, R A McKinney, B H Gähwiler, S M Thompso. Either N- or P-type calcium channels mediate GABA release at distinct hippocampal inhibitory synapses. Neuron. vol 18. issue 3. 1997-04-24. PMID:9115739. |
identification of the channels mediating gaba release in hippocampus is complicated by the heterogeneity of interneurons. |
1997-04-24 |
2023-08-12 |
Not clear |
| Y L Murashima, K Kassamo, J Suzuk. Developmental and seizure-related regional differences in immediate early gene expression and GABAergic abnormalities in the brain of EL mice. Epilepsy research. vol 26. issue 1. 1997-04-14. PMID:8985681. |
also to examine the 'gaba hypothesis' in epilepsy, gaba concentration and gad activity was determined in micro brain regions (10-300 ng) of el mice related to the focus in the parietal cortex and the hippocampus. |
1997-04-14 |
2023-08-12 |
mouse |
| G W Mathern, T L Babb, J P Leite, K Pretorius, K M Yeoman, P A Kuhlma. The pathogenic and progressive features of chronic human hippocampal epilepsy. Epilepsy research. vol 26. issue 1. 1997-04-14. PMID:8985697. |
hippocampal axon and synaptic reorganization is another pathologic feature of mtle, and involves granule cell mossy fibers and axons immunoreactive for neuropeptide upsilon, somatostatin, and glutamate decarboxylase (which synthesizes gaba). |
1997-04-14 |
2023-08-12 |
human |
| C L Wilson, N T Maidment, M H Shomer, E J Behnke, L Ackerson, I Fried, J Enge. Comparison of seizure related amino acid release in human epileptic hippocampus versus a chronic, kainate rat model of hippocampal epilepsy. Epilepsy research. vol 26. issue 1. 1997-04-14. PMID:8985704. |
in agreement with earlier reports, we found increases in glutamate, aspartate and gaba during seizures in human hippocampus. |
1997-04-14 |
2023-08-12 |
human |
| I Smolders, K Van Belle, G Ebinger, Y Michott. Hippocampal and cerebellar extracellular amino acids during pilocarpine-induced seizures in freely moving rats. European journal of pharmacology. vol 319. issue 1. 1997-04-14. PMID:9030893. |
changes in extracellular hippocampal and cerebellar glutamate, aspartate and gamma-aminobutyric acid (gaba) levels were monitored during and after pilocarpine administration. |
1997-04-14 |
2023-08-12 |
rat |
| I Smolders, K Van Belle, G Ebinger, Y Michott. Hippocampal and cerebellar extracellular amino acids during pilocarpine-induced seizures in freely moving rats. European journal of pharmacology. vol 319. issue 1. 1997-04-14. PMID:9030893. |
the changes in extracellular hippocampal amino-acid levels suggest that glutamate, aspartate and gaba are not involved in seizure onset, but may play a role in seizure maintenance and/or spread in the pilocarpine animal model of epilepsy. |
1997-04-14 |
2023-08-12 |
rat |
| R Sankar, D H Shin, C G Wasterlai. GABA metabolism during status epilepticus in the developing rat brain. Brain research. Developmental brain research. vol 98. issue 1. 1997-04-11. PMID:9027404. |
the rate of synthesis of gaba, the major inhibitory neurotransmitter, was determined in parietal cortex and hippocampus during se induced by systemic administration of lithium (3 meq/kg) followed 20 h later by pilocarpine (100 mg/kg) in 1-4-week-old rats. |
1997-04-11 |
2023-08-12 |
rat |
| R Sankar, D H Shin, C G Wasterlai. GABA metabolism during status epilepticus in the developing rat brain. Brain research. Developmental brain research. vol 98. issue 1. 1997-04-11. PMID:9027404. |
our results show that the immature hippocampus is better capable of maintaining gaba synthesis in the face of se at the earliest stages of development studied (74.1% of basal in 1-week-old) and that development results in a progressive decline in the ability to maintain gaba synthesis in the face of se (44.1% of basal by 4 weeks) that may parallel the ontogeny of self-sustaining seizures. |
1997-04-11 |
2023-08-12 |
rat |
| R Sankar, D H Shin, C G Wasterlai. GABA metabolism during status epilepticus in the developing rat brain. Brain research. Developmental brain research. vol 98. issue 1. 1997-04-11. PMID:9027404. |
our data describe an aspect of developmental gaba neurochemistry which may in part explain the relative resistance of the immature hippocampus to seizure spread and of certain types of seizure-induced damage. |
1997-04-11 |
2023-08-12 |
rat |
| J M Rho, S D Donevan, M A Rogawsk. Barbiturate-like actions of the propanediol dicarbamates felbamate and meprobamate. The Journal of pharmacology and experimental therapeutics. vol 280. issue 3. 1997-04-11. PMID:9067327. |
in whole-cell voltage-clamp recordings from cultured rat hippocampal neurons, meprobamate enhanced gaba-evoked responses in a concentration-dependent manner and, at high concentrations (>1 mm), exhibited a separate channel-blocking effect that limited the magnitude of gaba(a) receptor potentiation. |
1997-04-11 |
2023-08-12 |
rat |
| P Mohanakrishnan, A H Fowler, J P Vonsattel, P R Jolles, M M Husain, P Liem, L Myers, R A Komorosk. Regional metabolic alterations in Alzheimer's disease: an in vitro 1H NMR study of the hippocampus and cerebellum. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 52. issue 2. 1997-04-08. PMID:9060968. |
the gamma-aminobutyric acid levels in both hippocampus and cerebellum of an age- and a postmortem interval-matched subset of ad brains were lower than those of the controls. |
1997-04-08 |
2023-08-12 |
Not clear |
| V K Patchev, A Montkowski, D Rouskova, L Koranyi, F Holsboer, O F Almeid. Neonatal treatment of rats with the neuroactive steroid tetrahydrodeoxycorticosterone (THDOC) abolishes the behavioral and neuroendocrine consequences of adverse early life events. The Journal of clinical investigation. vol 99. issue 5. 1997-04-04. PMID:9062354. |
this study demonstrates that when applied concomitantly with the stressful challenge, the steroid gaba(a) receptor agonist 3,21-dihydropregnan-20-one (tetrahydrodeoxycorticosterone, thdoc) can attenuate the behavioral and neuroendocrine consequences of repeated maternal separation during early life, e.g., increased anxiety, an exaggerated adrenocortical secretory response to stress, impaired responsiveness to glucocorticoid feedback, and altered transcription of the genes encoding corticotropin-releasing hormone (crh) in the hypothalamus and glucocorticoid receptors in the hippocampus. |
1997-04-04 |
2023-08-12 |
rat |
| X Leinekugel, I Medina, I Khalilov, Y Ben-Ari, R Khazipo. Ca2+ oscillations mediated by the synergistic excitatory actions of GABA(A) and NMDA receptors in the neonatal hippocampus. Neuron. vol 18. issue 2. 1997-03-28. PMID:9052795. |
ca2+ oscillations mediated by the synergistic excitatory actions of gaba(a) and nmda receptors in the neonatal hippocampus. |
1997-03-28 |
2023-08-12 |
Not clear |
| X Leinekugel, I Medina, I Khalilov, Y Ben-Ari, R Khazipo. Ca2+ oscillations mediated by the synergistic excitatory actions of GABA(A) and NMDA receptors in the neonatal hippocampus. Neuron. vol 18. issue 2. 1997-03-28. PMID:9052795. |
we asked whether gaba(a) and nmda receptors may act in synergy in neonatal hippocampal slices, at a time when gaba exerts a depolarizing action. |
1997-03-28 |
2023-08-12 |
Not clear |