| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Zuiderwijk, E Veenstra, F H Lopes da Silva, W E Ghijse. Effects of uptake carrier blockers SK & F 89976-A and L-trans-PDC on in vivo release of amino acids in rat hippocampus. European journal of pharmacology. vol 307. issue 3. 1997-02-06. PMID:8836615. |
these results indicate that (1) in rat hippocampus uptake carriers actively regulate extracellular gaba and glutamate levels, (2) the gaba and glutamate released by k+ was derived from both ca(2+)-dependent (presumably vesicular) and ca(2+)-independent (presumably cytosolic) pools, whereas aspartate and taurine release was exclusively from ca(2+)-independent pools. |
1997-02-06 |
2023-08-12 |
rat |
| R Lucchi, S Latini, A de Mendonça, A M Sebastião, J A Ribeir. Adenosine by activating A1 receptors prevents GABAA-mediated actions during hypoxia in the rat hippocampus. Brain research. vol 732. issue 1-2. 1997-02-06. PMID:8891295. |
the relative contribution of adenosine and gamma-aminobutyric acid (gaba) for the hypoxia-induced depression of field excitatory postsynaptic potentials in the ca1 area of rat hippocampal slices, was investigated. |
1997-02-06 |
2023-08-12 |
rat |
| M Pfeiffer, A Draguhn, H Meierkord, U Heineman. Effects of gamma-aminobutyric acid (GABA) agonists and GABA uptake inhibitors on pharmacosensitive and pharmacoresistant epileptiform activity in vitro. British journal of pharmacology. vol 119. issue 3. 1997-02-06. PMID:8894180. |
gaba and the gabaa receptor agonist muscimol blocked both the pharmacosensitive discharges in the hippocampus and entorhinal cortex as well as the late recurrent discharges in the medial entorhinal cortex. |
1997-02-06 |
2023-08-12 |
rat |
| O Zachrisson, T Falkenberg, N Lindefor. Neuronal coexistence of trkB and glutamic acid decarboxylase67 mRNAs in rat hippocampus. Brain research. Molecular brain research. vol 36. issue 1. 1997-02-06. PMID:9011754. |
furthermore, we have observed that excitatory influence in the hippocampus seems to increase in vivo release of gamma-aminobutyric acid (gaba), indicated by microdialysis perfusion of the ca1 region. |
1997-02-06 |
2023-08-12 |
rat |
| O Zachrisson, T Falkenberg, N Lindefor. Neuronal coexistence of trkB and glutamic acid decarboxylase67 mRNAs in rat hippocampus. Brain research. Molecular brain research. vol 36. issue 1. 1997-02-06. PMID:9011754. |
this finding indicates that trkb can be synthesized in gaba producing neurons in the hippocampus. |
1997-02-06 |
2023-08-12 |
rat |
| M A Hutchinson, P F Smith, C L Darlingto. Tolerance to the ataxic effects of diazepam in guinea pig is not associated with a reduced sensitivity of GABAA receptors in the vestibular nucleus. European journal of pharmacology. vol 301. issue 1-3. 1997-02-04. PMID:8773450. |
some studies have suggested that drug tolerance observed following repeated benzodiazepine exposure may be associated with the development of a subsensitivity to gamma-aminobutyric acid (gaba) in dorsal raphe and hippocampal neurons. |
1997-02-04 |
2023-08-12 |
Not clear |
| S M Thompson, C Fortunato, R A McKinney, M Müller, B H Gähwile. Mechanisms underlying the neuropathological consequences of epileptic activity in the rat hippocampus in vitro. The Journal of comparative neurology. vol 372. issue 4. 1997-01-29. PMID:8876450. |
blockage of gamma-aminobutyric acid (gaba)ergic synaptic transmission in mature hippocampal slice cultures for a period of 3 days with convulsants was shown previously to induce chronic epileptiform activity and to mimic many of the degenerative changes observed in the hippocampi of epileptic humans. |
1997-01-29 |
2023-08-12 |
rat |
| M Serra, L Dazzi, E Cagetti, M F Chessa, M G Pisu, A Sanna, G Biggi. Effect of pentylenetetrazole-induced kindling on acetylcholine release in the hippocampus of freely moving rats. Journal of neurochemistry. vol 68. issue 1. 1997-01-27. PMID:8978740. |
hippocampal acetylcholine release was evaluated with the microdialysis technique in freely moving rats either after acute administration of isoniazid (an inhibitor of gaba synthesis) or pentylenetetrazole (ptz) (a blocker of the gabaa receptor-associated cl- channel) or after chronic administration of ptz. |
1997-01-27 |
2023-08-12 |
rat |
| E Dell'Anna, M C Geloso, M Magarelli, M Molinar. Development of GABA and calcium binding proteins immunoreactivity in the rat hippocampus following neonatal anoxia. Neuroscience letters. vol 211. issue 2. 1997-01-23. PMID:8830852. |
development of gaba and calcium binding proteins immunoreactivity in the rat hippocampus following neonatal anoxia. |
1997-01-23 |
2023-08-12 |
rat |
| E Dell'Anna, M C Geloso, M Magarelli, M Molinar. Development of GABA and calcium binding proteins immunoreactivity in the rat hippocampus following neonatal anoxia. Neuroscience letters. vol 211. issue 2. 1997-01-23. PMID:8830852. |
the consequences of neonatal anoxia (n2 100% for 25 min at 30 h after birth) on the rat hippocampus were studied 7-60 days postnatally with immunocytochemistry for gamma-aminobutyric acid (gaba), parvalbumin (pv) and calbindin-d28k (cb). |
1997-01-23 |
2023-08-12 |
rat |
| V Itier, P Granger, G Perrault, H Depoortere, B Scatton, P Avene. Protracted treatment with diazepam reduces benzodiazepine1 receptor-mediated potentiation of gamma-aminobutyric acid-induced currents in dissociated rat hippocampal neurons. The Journal of pharmacology and experimental therapeutics. vol 279. issue 3. 1997-01-23. PMID:8968329. |
the specific current induced by 1 microm gaba in acutely dissociated hippocampal neurons 48 hr after withdrawal (10.5 +/- 1.3 microa/cm2) was similar to that observed in the control rats (8.7 +/- 0.8 microa/cm2). |
1997-01-23 |
2023-08-12 |
rat |
| M Alkondon, E F Pereira, E X Albuquerqu. Mapping the location of functional nicotinic and gamma-aminobutyric acidA receptors on hippocampal neurons. The Journal of pharmacology and experimental therapeutics. vol 279. issue 3. 1997-01-23. PMID:8968375. |
to assess the density and distribution of functional nicotinic acetylcholine receptors (nachrs) and gamma-aminobutyric acid (gaba) receptors on hippocampal neurons, we have combined infrared videomicroscopy with a nanorobotic micromanipulator system and studied the receptor-mediated currents by using the whole-cell patch-clamp technique. |
1997-01-23 |
2023-08-12 |
Not clear |
| M Alkondon, E F Pereira, E X Albuquerqu. Mapping the location of functional nicotinic and gamma-aminobutyric acidA receptors on hippocampal neurons. The Journal of pharmacology and experimental therapeutics. vol 279. issue 3. 1997-01-23. PMID:8968375. |
acetylcholine or gaba was applied by pressure ejection onto a small segment of either cell soma or dendrite, and the resulting current was measured in cultured hippocampal neurons by using a whole-cell pipette positioned at the cell soma. |
1997-01-23 |
2023-08-12 |
Not clear |
| M Alkondon, E F Pereira, E X Albuquerqu. Mapping the location of functional nicotinic and gamma-aminobutyric acidA receptors on hippocampal neurons. The Journal of pharmacology and experimental therapeutics. vol 279. issue 3. 1997-01-23. PMID:8968375. |
exposure of cultured hippocampal neurons to colchicine (100 nm for 3 days) produced a dramatic reduction in the dendritic branching, and this morphological feature was associated with a significant decrease in the receptor density, such an effect being more prominent for nachrs than for gaba receptors. |
1997-01-23 |
2023-08-12 |
Not clear |
| M Isokaw. Decrement of GABAA receptor-mediated inhibitory postsynaptic currents in dentate granule cells in epileptic hippocampus. Journal of neurophysiology. vol 75. issue 5. 1997-01-16. PMID:8734589. |
i conclude that, when intensively activated, nmda receptor-mediated excitatory transmission may interact with gabaergic synaptic inhibition in dgcs in seizure-experienced hippocampus to transiently reduce gaba(a) receptor-channel function. |
1997-01-16 |
2023-08-12 |
human |
| I M Kapetanovic, W D Yonekawa, H J Kupferber. The effects of D-23129, a new experimental anticonvulsant drug, on neurotransmitter amino acids in the rat hippocampus in vitro. Epilepsy research. vol 22. issue 3. 1997-01-15. PMID:8991783. |
their effects on de novo synthesis of excitatory (glutamate and aspartate) and inhibitory (gaba) amino acids were studied in rat hippocampal slices. |
1997-01-15 |
2023-08-12 |
rat |
| M A Whittington, J G Jefferys, R D Trau. Effects of intravenous anaesthetic agents on fast inhibitory oscillations in the rat hippocampus in vitro. British journal of pharmacology. vol 118. issue 8. 1997-01-06. PMID:8864532. |
trains of fast oscillations, shown previously to be shaped by gamma-aminobutyric acid (gabaa) receptor activation, were evoked by pressure ejection of l-glutamate (10 nm) onto the perisomatic region of hippocampal area cai in the presence of 3-((r)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (r-cpp), 50 microm, 6-nitro-7-sulphamoylbenzo[f]quinoxaline-2,3-dione (nbqx), 50 microm and 2-hydroxysaclofen, 0.2 mm. |
1997-01-06 |
2023-08-12 |
rat |
| M A Wilso. GABA physiology: modulation by benzodiazepines and hormones. Critical reviews in neurobiology. vol 10. issue 1. 1997-01-03. PMID:8853952. |
regionally specific adaptations to chronic bz treatments that lead to the development of tolerance include the following: intrinsic subsensitivity to gaba, reduced activity in gabaergic circuits (e.g., reduced recurrent inhibition in hippocampus), attenuated responses to bzs without alterations in gaba sensitivity, modulation of the intrinsic properties of neurons, and alterations in the activity of non-gabaergic afferent inputs. |
1997-01-03 |
2023-08-12 |
Not clear |
| M A Wilso. GABA physiology: modulation by benzodiazepines and hormones. Critical reviews in neurobiology. vol 10. issue 1. 1997-01-03. PMID:8853952. |
this neurosteroid also enhances gaba responses in hippocampal slices, including recurrent inhibition, in a bz-like manner. |
1997-01-03 |
2023-08-12 |
Not clear |
| S Leonard, C Adams, C R Breese, L E Adler, P Bickford, W Byerley, H Coon, J M Griffith, C Miller, M Myles-Worsley, H T Nagamoto, Y Rollins, K E Stevens, M Waldo, R Freedma. Nicotinic receptor function in schizophrenia. Schizophrenia bulletin. vol 22. issue 3. 1997-01-02. PMID:8873294. |
an inhibitory mechanism, in the hippocampus, may involve nicotinic stimulation of gamma-aminobutyric acid (gaba)ergic interneurons, resulting in decreased response to repetitive stimuli. |
1997-01-02 |
2023-08-12 |
human |