| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Saransaari, S S Oj. Enhanced GABA release in cell-damaging conditions in the adult and developing mouse hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 15. issue 2. 1997-07-22. PMID:9178035. |
enhanced gaba release in cell-damaging conditions in the adult and developing mouse hippocampus. |
1997-07-22 |
2023-08-12 |
mouse |
| P Saransaari, S S Oj. Enhanced GABA release in cell-damaging conditions in the adult and developing mouse hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 15. issue 2. 1997-07-22. PMID:9178035. |
the release of [3h]gaba from hippocampal slices from adult (3-month-old) and developing (7-day-old) mice was studied in cell-damaging conditions in vitro using a superfusion system. |
1997-07-22 |
2023-08-12 |
mouse |
| P Saransaari, S S Oj. Enhanced GABA release in cell-damaging conditions in the adult and developing mouse hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 15. issue 2. 1997-07-22. PMID:9178035. |
the basal release of gaba from the immature and mature hippocampus was generally markedly increased in all cell-damaging conditions. |
1997-07-22 |
2023-08-12 |
mouse |
| P Saransaari, S S Oj. Enhanced GABA release in cell-damaging conditions in the adult and developing mouse hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 15. issue 2. 1997-07-22. PMID:9178035. |
it was shown by superfusing the slices in ca- and na-free media that ischemia-induced gaba release was ca-independent, occurring by a reversed operation of na-dependent cell membrane carriers in both adult and developing hippocampus. |
1997-07-22 |
2023-08-12 |
mouse |
| P Saransaari, S S Oj. Enhanced GABA release in cell-damaging conditions in the adult and developing mouse hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 15. issue 2. 1997-07-22. PMID:9178035. |
glutamate and its receptor agonists, n-methyl-d-aspartate (nmda), kainate and 2-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (ampa), potentiated gaba release only in the immature hippocampus by a receptor-mediated mechanism. |
1997-07-22 |
2023-08-12 |
mouse |
| P Saransaari, S S Oj. Enhanced GABA release in cell-damaging conditions in the adult and developing mouse hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 15. issue 2. 1997-07-22. PMID:9178035. |
the massive amount of gaba released simultaneously with excitatory amino acids in the mature and immature hippocampus may be an important protective mechanism against excitotoxicity, counteracting harmful effects that lead to neuronal death. |
1997-07-22 |
2023-08-12 |
mouse |
| P Saransaari, S S Oj. Enhanced GABA release in cell-damaging conditions in the adult and developing mouse hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 15. issue 2. 1997-07-22. PMID:9178035. |
the gaba release induced by activation of presynaptic glutamate receptors may contribute particularly to the maintenance of homeostasis in the hippocampus upon impending hyperexcitation. |
1997-07-22 |
2023-08-12 |
mouse |
| M Eghbali, J P Curmi, B Birnir, P W Gag. Hippocampal GABA(A) channel conductance increased by diazepam. Nature. vol 388. issue 6637. 1997-07-21. PMID:9214504. |
hippocampal gaba(a) channel conductance increased by diazepam. |
1997-07-21 |
2023-08-12 |
rat |
| M Eghbali, J P Curmi, B Birnir, P W Gag. Hippocampal GABA(A) channel conductance increased by diazepam. Nature. vol 388. issue 6637. 1997-07-21. PMID:9214504. |
here we show that the benzodiazepine diazepam can also increase the conductance of gabaa channels activated by low concentrations of gaba (0.5 or 5 microm) in rat cultured hippocampal neurons. |
1997-07-21 |
2023-08-12 |
rat |
| K K Miller, A Hoffer, K R Svoboda, C R Lupic. Cholecystokinin increases GABA release by inhibiting a resting K+ conductance in hippocampal interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 13. 1997-07-17. PMID:9185537. |
cholecystokinin increases gaba release by inhibiting a resting k+ conductance in hippocampal interneurons. |
1997-07-17 |
2023-08-12 |
rat |
| K K Miller, A Hoffer, K R Svoboda, C R Lupic. Cholecystokinin increases GABA release by inhibiting a resting K+ conductance in hippocampal interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 13. 1997-07-17. PMID:9185537. |
cholecystokinin (cck) is found co-localized with the inhibitory neurotransmitter gaba in interneurons of the hippocampus. |
1997-07-17 |
2023-08-12 |
rat |
| S Marty, Berzaghi MdaP, B Berninge. Neurotrophins and activity-dependent plasticity of cortical interneurons. Trends in neurosciences. vol 20. issue 5. 1997-07-10. PMID:9141194. |
neocortical and hippocampal gaba-containing interneurons are susceptible to activity-dependent modulation, such as regulation of soma size, numbers of synaptic contacts, and levels of gaba or neuropeptide expression. |
1997-07-10 |
2023-08-12 |
mouse |
| C Song, B Earley, B E Leonar. Effect of chronic treatment with piracetam and tacrine on some changes caused by thymectomy in the rat brain. Pharmacology, biochemistry, and behavior. vol 56. issue 4. 1997-07-07. PMID:9130296. |
the concentration of gamma amino butyric acid (gaba) was determined in amygdaloid cortex and hippocampus only. |
1997-07-07 |
2023-08-12 |
rat |
| J W Gibbs, M D Shumate, D A Coulte. Differential epilepsy-associated alterations in postsynaptic GABA(A) receptor function in dentate granule and CA1 neurons. Journal of neurophysiology. vol 77. issue 4. 1997-07-02. PMID:9114245. |
these regionally distinct epilepsy-associated modifications in hippocampal gabaergic function may be due to discrete structural alterations in postsynaptic gaba(a)rs accompanying epileptogenesis, could be therapeutically important, and undoubtedly could contribute to the enhanced limbic excitability underlying tle. |
1997-07-02 |
2023-08-12 |
rat |
| M Ouardouz, J C Lacaill. Properties of unitary IPSCs in hippocampal pyramidal cells originating from different types of interneurons in young rats. Journal of neurophysiology. vol 77. issue 4. 1997-07-02. PMID:9114246. |
our results indicate that these different subtypes of hippocampal interneurons generate cl(-)-mediated gaba(a) uipscs. |
1997-07-02 |
2023-08-12 |
human |
| V Crépel, R Khazipov, Y Ben-Ar. Blocking GABA(A) inhibition reveals AMPA- and NMDA-receptor-mediated polysynaptic responses in the CA1 region of the rat hippocampus. Journal of neurophysiology. vol 77. issue 4. 1997-07-02. PMID:9114256. |
blocking gaba(a) inhibition reveals ampa- and nmda-receptor-mediated polysynaptic responses in the ca1 region of the rat hippocampus. |
1997-07-02 |
2023-08-12 |
rat |
| J W Gibbs, S Sombati, R J DeLorenzo, D A Coulte. Physiological and pharmacological alterations in postsynaptic GABA(A) receptor function in a hippocampal culture model of chronic spontaneous seizures. Journal of neurophysiology. vol 77. issue 4. 1997-07-02. PMID:9114261. |
physiological and pharmacological alterations in postsynaptic gaba(a) receptor function in a hippocampal culture model of chronic spontaneous seizures. |
1997-07-02 |
2023-08-12 |
rat |
| J W Gibbs, S Sombati, R J DeLorenzo, D A Coulte. Physiological and pharmacological alterations in postsynaptic GABA(A) receptor function in a hippocampal culture model of chronic spontaneous seizures. Journal of neurophysiology. vol 77. issue 4. 1997-07-02. PMID:9114261. |
in patch-clamp recordings from hippocampal pyramidal cells from "epileptic," low mg2+ pretreated hippocampal cultures, a rapid (within 2 h of treatment), permanent (lasting > or = 8 days) and statistically significant 50-65% reduction in the current density of functional gamma-aminobutyric acid-a (gaba(a)) receptors was evident when the gaba responses of these cells were compared with control neurons. |
1997-07-02 |
2023-08-12 |
rat |
| J W Gibbs, S Sombati, R J DeLorenzo, D A Coulte. Physiological and pharmacological alterations in postsynaptic GABA(A) receptor function in a hippocampal culture model of chronic spontaneous seizures. Journal of neurophysiology. vol 77. issue 4. 1997-07-02. PMID:9114261. |
the kinetics of gaba current block by the noncompetitive antagonist picrotoxin were determined in hippocampal cultured neurons, and an ic50 of 14 microm determined. |
1997-07-02 |
2023-08-12 |
rat |
| Y De Koninck, I Mod. Endogenous GABA activates small-conductance K+ channels underlying slow IPSCs in rat hippocampal neurons. Journal of neurophysiology. vol 77. issue 4. 1997-07-02. PMID:9114267. |
endogenous gaba activates small-conductance k+ channels underlying slow ipscs in rat hippocampal neurons. |
1997-07-02 |
2023-08-12 |
rat |