| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Lamsa, J M Palva, E Ruusuvuori, K Kaila, T Tair. Synaptic GABA(A) activation inhibits AMPA-kainate receptor-mediated bursting in the newborn (P0-P2) rat hippocampus. Journal of neurophysiology. vol 83. issue 1. 2000-02-16. PMID:10634879. |
synaptic gaba(a) activation inhibits ampa-kainate receptor-mediated bursting in the newborn (p0-p2) rat hippocampus. |
2000-02-16 |
2023-08-12 |
rat |
| K Lamsa, J M Palva, E Ruusuvuori, K Kaila, T Tair. Synaptic GABA(A) activation inhibits AMPA-kainate receptor-mediated bursting in the newborn (P0-P2) rat hippocampus. Journal of neurophysiology. vol 83. issue 1. 2000-02-16. PMID:10634879. |
in the present study field potential recordings and gramicidin perforated and whole cell clamp techniques as well as k(+)-selective microelectrodes were used to examine the relative contributions of ampa and gaba(a) receptors to network activity of ca3-ca1 pyramidal cells in the newborn rat hippocampus. |
2000-02-16 |
2023-08-12 |
rat |
| K Lamsa, J M Palva, E Ruusuvuori, K Kaila, T Tair. Synaptic GABA(A) activation inhibits AMPA-kainate receptor-mediated bursting in the newborn (P0-P2) rat hippocampus. Journal of neurophysiology. vol 83. issue 1. 2000-02-16. PMID:10634879. |
concurrently, although gaba(a)-r-mediated depolarization may excite hippocampal interneurons, in ca3 pyramidal neurons it can restrain excitatory inputs and limit the size of the activated neuronal population. |
2000-02-16 |
2023-08-12 |
rat |
| I Khalilov, V Dzhala, Y Ben-Ari, R Khazipo. Dual role of GABA in the neonatal rat hippocampus. Developmental neuroscience. vol 21. issue 3-5. 2000-02-10. PMID:10575254. |
dual role of gaba in the neonatal rat hippocampus. |
2000-02-10 |
2023-08-12 |
rat |
| M Good, M Day, J L Mui. Cyclical changes in endogenous levels of oestrogen modulate the induction of LTD and LTP in the hippocampal CA1 region. The European journal of neuroscience. vol 11. issue 12. 2000-02-10. PMID:10594677. |
these findings are discussed with reference to: (i) the modulatory effects of oestrogen on n-methyl-d-aspartate (nmda) receptor function and gamma-aminobutyric acid (gaba) neurotransmission in the hippocampus; and (ii) the functional implications that such cyclical changes in synaptic plasticity have for learning and memory processes supported by the hippocampus. |
2000-02-10 |
2023-08-12 |
rat |
| H M Sinnamon, A K Jassen, C Ilc. Hippocampal theta activity and facilitated locomotor stepping produced by GABA injections in the midbrain raphe region. Behavioural brain research. vol 107. issue 1-2. 2000-01-31. PMID:10628733. |
hippocampal theta activity and facilitated locomotor stepping produced by gaba injections in the midbrain raphe region. |
2000-01-31 |
2023-08-12 |
rat |
| H M Sinnamon, A K Jassen, C Ilc. Hippocampal theta activity and facilitated locomotor stepping produced by GABA injections in the midbrain raphe region. Behavioural brain research. vol 107. issue 1-2. 2000-01-31. PMID:10628733. |
gaba injections were used to locate raphe sites at which neuronal inactivation influenced stepping and hippocampal activity. |
2000-01-31 |
2023-08-12 |
rat |
| C N Connolly, J T Kittler, P Thomas, J M Uren, N J Brandon, T G Smart, S J Mos. Cell surface stability of gamma-aminobutyric acid type A receptors. Dependence on protein kinase C activity and subunit composition. The Journal of biological chemistry. vol 274. issue 51. 2000-01-27. PMID:10593956. |
similar gaba(a) receptor endocytosis was also seen in cultured hippocampal and cortical neurons. |
2000-01-27 |
2023-08-12 |
human |
| K M Crowder, J M Gunther, T A Jones, B D Hale, H Z Zhang, M R Peterson, R H Scheller, C Chavkin, S M Bajjalie. Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A). Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 26. 2000-01-27. PMID:10611374. |
electrophysiological studies of spontaneous inhibitory neurotransmission in the ca3 region of the hippocampus revealed that loss of sv2a leads to a reduction in action potential-dependent gamma-aminobutyric acid (gaba)ergic neurotransmission. |
2000-01-27 |
2023-08-12 |
mouse |
| W Y Kao, Q Y Liu, W Ma, G D Ritchie, J Lin, A F Nordholm, J Rossi, J L Barker, D A Stenger, J J Pancrazi. Inhibition of spontaneous GABAergic transmission by trimethylolpropane phosphate. Neurotoxicology. vol 20. issue 5. 2000-01-24. PMID:10591520. |
using the whole-cell patch clamp method, spontaneous inhibitory postsynaptic currents (sipscs) mediated by bicuculline-sensitive gaba(a) receptors were measured in neurons cultured from the rat embryonic hippocampus for 13-21 days. |
2000-01-24 |
2023-08-12 |
rat |
| S Oh, I K H. Changes of [3H]muscimol binding and GABA(A) receptor beta2-subunit mRNA level by tolerance to and withdrawal from pentobarbital in rats. Neurochemical research. vol 24. issue 12. 2000-01-10. PMID:10591412. |
the gaba(a) receptor beta2-subunit mrna was increased in the withdrawal rats only: in the cortex (9-14%), hippocampus (15-21%), inferior colliculus (21%), and granule layer of cerebellum (24%). |
2000-01-10 |
2023-08-12 |
rat |
| D Bai, P S Pennefather, J F MacDonald, B A Orse. The general anesthetic propofol slows deactivation and desensitization of GABA(A) receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 24. 2000-01-06. PMID:10594047. |
gaba was applied using a fast perfusion system to nucleated patches excised from hippocampal neurons. |
2000-01-06 |
2023-08-12 |
Not clear |
| Y Levkovitz, E Avignone, Y Groner, M Sega. Upregulation of GABA neurotransmission suppresses hippocampal excitability and prevents long-term potentiation in transgenic superoxide dismutase-overexpressing mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 24. 2000-01-06. PMID:10594078. |
upregulation of gaba neurotransmission suppresses hippocampal excitability and prevents long-term potentiation in transgenic superoxide dismutase-overexpressing mice. |
2000-01-06 |
2023-08-12 |
mouse |
| B S Meldrum, A G Chapma. Basic mechanisms of gabitril (tiagabine) and future potential developments. Epilepsia. vol 40 Suppl 9. 2000-01-05. PMID:10612355. |
gabitril (tiagabine) is a potent selective inhibitor of the principal neuronal gamma-aminobutyric acid (gaba) transporter (gat-1) in the cortex and hippocampus. |
2000-01-05 |
2023-08-12 |
Not clear |
| C Psarropoulou, S Descombe. Differential bicuculline-induced epileptogenesis in rat neonatal, juvenile and adult CA3 pyramidal neurons in vitro. Brain research. Developmental brain research. vol 117. issue 1. 1999-12-28. PMID:10536239. |
the gaba(a) receptor antagonist bicuculline methiodide (bmi, 10 microm) transformed the evoked synaptic responses, recorded intracellularly from the ca3 area of neonatal (postnatal days 3-7, p3-p7), juvenile (p8-p20) and adult hippocampal slices, into long-lasting paroxysmal depolarizations (pds), with repetitive action potentials (aps). |
1999-12-28 |
2023-08-12 |
rat |
| J L Velazquez, P L Carle. Synchronization of GABAergic interneuronal networks during seizure-like activity in the rat horizontal hippocampal slice. The European journal of neuroscience. vol 11. issue 11. 1999-12-28. PMID:10583499. |
we studied the contribution of gabaergic (gamma-aminobutyric acid) neurotransmission to epileptiform activity using the horizontal hippocampal rat brain slice. |
1999-12-28 |
2023-08-12 |
rat |
| M M Durkin, C A Gunwaldsen, B Borowsky, K A Jones, T A Branche. An in situ hybridization study of the distribution of the GABA(B2) protein mRNA in the rat CNS. Brain research. Molecular brain research. vol 71. issue 2. 1999-12-23. PMID:10521573. |
the highest levels of gaba(b2) mrna expression were detected in the piriform cortex, hippocampus, and medial habenula. |
1999-12-23 |
2023-08-12 |
rat |
| S A Farr, K Uezu, J F Flood, J E Morle. Septo-hippocampal drug interactions in post-trial memory processing. Brain research. vol 847. issue 2. 1999-12-21. PMID:10575091. |
to determine if serotonin and gaba regulate post-trial memory processing of the cholinergic projection from the septum to the hippocampus, mice were trained on footshock avoidance in a t-maze. |
1999-12-21 |
2023-08-12 |
mouse |
| S A Farr, K Uezu, J F Flood, J E Morle. Septo-hippocampal drug interactions in post-trial memory processing. Brain research. vol 847. issue 2. 1999-12-21. PMID:10575091. |
bicuculline, a gaba(a) receptor antagonist at a dose of 0.1 pg, did not affect retention when injected alone into the septum, but it reduced the dose of arecoline needed to improve retention in the hippocampus. |
1999-12-21 |
2023-08-12 |
mouse |
| S A Farr, K Uezu, J F Flood, J E Morle. Septo-hippocampal drug interactions in post-trial memory processing. Brain research. vol 847. issue 2. 1999-12-21. PMID:10575091. |
the results of this study are compatible with models that propose that serotonin innervation from the median raphe drives gaba interneurons in the medial septum that synapse on cholinergic neurons projecting to the hippocampus. |
1999-12-21 |
2023-08-12 |
mouse |