| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Bast, W N Zhang, J Feldo. Hyperactivity, decreased startle reactivity, and disrupted prepulse inhibition following disinhibition of the rat ventral hippocampus by the GABA(A) receptor antagonist picrotoxin. Psychopharmacology. vol 156. issue 2-3. 2002-01-28. PMID:11549225. |
neuropathological data indicate that hyperactivity of excitatory hippocampal afferents and decreased hippocampal gaba transmission contribute to this overactivity. |
2002-01-28 |
2023-08-12 |
rat |
| G T Finnerty, M A Whittington, J G Jeffery. Altered dentate filtering during the transition to seizure in the rat tetanus toxin model of epilepsy. Journal of neurophysiology. vol 86. issue 6. 2002-01-28. PMID:11731534. |
we found that the biphasic profile and rate of potentiation of dentate population spikes in vivo can be reproduced in naïve hippocampal slices by blocking gaba(b) receptors. |
2002-01-28 |
2023-08-12 |
rat |
| H Yu, R K Iyer, R M Kern, W I Rodriguez, W W Grody, S D Cederbau. Expression of arginase isozymes in mouse brain. Journal of neuroscience research. vol 66. issue 3. 2002-01-25. PMID:11746358. |
glutamic acid decarboxylase 65 and glutamic acid decarboxylase 67, postulated to be related to the risk of glutamate excitotoxic and/or gamma-aminobutyric acid inhibitoxic injury, were similarly ubiquitous in their expression and generally paralleled arginase expression patterns, especially in cerebral cortex, hippocampus, cerebellum, pons, medulla, and spinal cord. |
2002-01-25 |
2023-08-12 |
mouse |
| N A Datson, J van der Perk, E R de Kloet, E Vreugdenhi. Expression profile of 30,000 genes in rat hippocampus using SAGE. Hippocampus. vol 11. issue 4. 2002-01-23. PMID:11530848. |
comparison of relative expression levels demonstrated that glutamate receptors are the most frequent neurotransmitter receptors expressed in the hippocampus, consistent with the important role of glutamatergic neurotransmission in the hippocampus, while gaba receptors were present at approximately 10-fold lower levels. |
2002-01-23 |
2023-08-12 |
rat |
| G G Ortiz, Y Sánchez-Ruiz, D X Tan, R J Reiter, G Benítez-King, C Beas-Zárat. Melatonin, vitamin E, and estrogen reduce damage induced by kainic acid in the hippocampus: potassium-stimulated GABA release. Journal of pineal research. vol 31. issue 1. 2002-01-22. PMID:11485006. |
melatonin, vitamin e, and estrogen reduce damage induced by kainic acid in the hippocampus: potassium-stimulated gaba release. |
2002-01-22 |
2023-08-12 |
mouse |
| G G Ortiz, Y Sánchez-Ruiz, D X Tan, R J Reiter, G Benítez-King, C Beas-Zárat. Melatonin, vitamin E, and estrogen reduce damage induced by kainic acid in the hippocampus: potassium-stimulated GABA release. Journal of pineal research. vol 31. issue 1. 2002-01-22. PMID:11485006. |
the aim of the present study was to examine the changes in potassium-evoked gamma-aminobutyric acid (gaba) release in the hippocampus of ka-treated rats and to test the possible protective effects of melatonin, vitamin e or estrogen. |
2002-01-22 |
2023-08-12 |
mouse |
| S A Hart, J D Patton, C S Woolle. Quantitative analysis of ER alpha and GAD colocalization in the hippocampus of the adult female rat. The Journal of comparative neurology. vol 440. issue 2. 2002-01-22. PMID:11745614. |
because inhibitory neurons may be involved in the effects of estrogen on hippocampal principal cells, quantitative description of er alpha expression in gamma-aminobutyric acid (gaba)ergic (inhibitory) and non-gabaergic cells of the hippocampus is a key step in understanding the mechanism(s) of estrogen action on hippocampal circuitry. |
2002-01-22 |
2023-08-12 |
rat |
| T Irie, E Miyamoto, K Kitagawa, Y Maruyama, K Inoue, C Inagak. An anxiolytic agent, dihydrohonokiol-B, inhibits ammonia-induced increases in the intracellular Cl(-) of cultured rat hippocampal neurons via GABA(c) receptors. Neuroscience letters. vol 312. issue 2. 2002-01-15. PMID:11595349. |
an anxiolytic agent, dihydrohonokiol-b, inhibits ammonia-induced increases in the intracellular cl(-) of cultured rat hippocampal neurons via gaba(c) receptors. |
2002-01-15 |
2023-08-12 |
rat |
| P Saransaari, S S Oj. Metabotropic glutamate receptors modulate GABA release from mouse hippocampal slices. Neurochemical research. vol 26. issue 2. 2002-01-14. PMID:11478745. |
metabotropic glutamate receptors modulate gaba release from mouse hippocampal slices. |
2002-01-14 |
2023-08-12 |
mouse |
| P Saransaari, S S Oj. Metabotropic glutamate receptors modulate GABA release from mouse hippocampal slices. Neurochemical research. vol 26. issue 2. 2002-01-14. PMID:11478745. |
the effects of metabotropic glutamate receptor agonists on the basal and potassium (50 mm k+)-stimulated release of [3h]gaba from mouse hippocampal slices were investigated using a superfusion system. |
2002-01-14 |
2023-08-12 |
mouse |
| P Saransaari, S S Oj. Metabotropic glutamate receptors modulate GABA release from mouse hippocampal slices. Neurochemical research. vol 26. issue 2. 2002-01-14. PMID:11478745. |
the results show that activation of metabotropic glutamate receptors of group i is able to potentiate the basal release of gaba, whereas activation of groups i and iii receptors reduce k+-stimulated release in mouse hippocampal slices. |
2002-01-14 |
2023-08-12 |
mouse |
| K Tominaga, A Yamauchi, H Shuto, M Niizeki, K Makino, R Oishi, Y Kataok. Ovariectomy aggravates convulsions and hippocampal gamma-aminobutyric acid inhibition induced by cyclosporin A in rats. European journal of pharmacology. vol 430. issue 2-3. 2002-01-14. PMID:11711037. |
ovariectomy aggravates convulsions and hippocampal gamma-aminobutyric acid inhibition induced by cyclosporin a in rats. |
2002-01-14 |
2023-08-12 |
rat |
| K Tominaga, A Yamauchi, H Shuto, M Niizeki, K Makino, R Oishi, Y Kataok. Ovariectomy aggravates convulsions and hippocampal gamma-aminobutyric acid inhibition induced by cyclosporin A in rats. European journal of pharmacology. vol 430. issue 2-3. 2002-01-14. PMID:11711037. |
the present study was aimed at elucidating the effect of cyclosporin a on the convulsive activity and gamma-aminobutyric acid (gaba) neural activity of the hippocampus in ovariectomized rats, as a menopause/climacterium model. |
2002-01-14 |
2023-08-12 |
rat |
| K Tominaga, A Yamauchi, H Shuto, M Niizeki, K Makino, R Oishi, Y Kataok. Ovariectomy aggravates convulsions and hippocampal gamma-aminobutyric acid inhibition induced by cyclosporin A in rats. European journal of pharmacology. vol 430. issue 2-3. 2002-01-14. PMID:11711037. |
the present findings demonstrated that ovariectomy increased the susceptibility to cyclosporin a-induced convulsions by accelerating an inhibitory action of cyclosporin a on gaba neural activity in the hippocampus, this being blocked by estrogen replacement. |
2002-01-14 |
2023-08-12 |
rat |
| F Nava, G Carta, M Bortolato, G L Gess. gamma-Hydroxybutyric acid and baclofen decrease extracellular acetylcholine levels in the hippocampus via GABA(B) receptors. European journal of pharmacology. vol 430. issue 2-3. 2002-01-14. PMID:11711039. |
gamma-hydroxybutyric acid and baclofen decrease extracellular acetylcholine levels in the hippocampus via gaba(b) receptors. |
2002-01-14 |
2023-08-12 |
rat |
| F Nava, G Carta, M Bortolato, G L Gess. gamma-Hydroxybutyric acid and baclofen decrease extracellular acetylcholine levels in the hippocampus via GABA(B) receptors. European journal of pharmacology. vol 430. issue 2-3. 2002-01-14. PMID:11711039. |
the effect of gamma-hydroxybutyric acid (ghb) and baclofen, a gaba(b) receptor agonist, on extracellular hippocampal acetylcholine levels was studied in freely moving rats by microdialysis. |
2002-01-14 |
2023-08-12 |
rat |
| F Nava, G Carta, M Bortolato, G L Gess. gamma-Hydroxybutyric acid and baclofen decrease extracellular acetylcholine levels in the hippocampus via GABA(B) receptors. European journal of pharmacology. vol 430. issue 2-3. 2002-01-14. PMID:11711039. |
reduced in a dose-dependent manner, extracellular hippocampal acetylcholine concentrations and this effect was prevented by the gaba(b) receptor antagonist (2s)(+)-5,5-dimethyl-2-morpholineacetic acid (sch 50911), at the dose of 20 mg/kg (i.p. |
2002-01-14 |
2023-08-12 |
rat |
| F Nava, G Carta, M Bortolato, G L Gess. gamma-Hydroxybutyric acid and baclofen decrease extracellular acetylcholine levels in the hippocampus via GABA(B) receptors. European journal of pharmacology. vol 430. issue 2-3. 2002-01-14. PMID:11711039. |
these findings indicate that ghb-induced reduction of hippocampal acetylcholine release is mediated by gaba(b) receptors and support a possible involvement of hippocampal gaba(b) receptors in the control of cognitive processes and in the claimed amnesic effect of ghb intoxication. |
2002-01-14 |
2023-08-12 |
rat |
| S G Brickley, M Farrant, G T Swanson, S G Cull-Cand. CNQX increases GABA-mediated synaptic transmission in the cerebellum by an AMPA/kainate receptor-independent mechanism. Neuropharmacology. vol 41. issue 6. 2002-01-10. PMID:11640927. |
however, for nearly a decade it has been known that, in the hippocampus, one of the most commonly used alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa)/kainate receptor antagonists, 6-cyano-7-nitroquinoxaline-2,3-dione (cnqx), can increase the frequency of spontaneous gaba(a) receptor-mediated postsynaptic currents (sipscs). |
2002-01-10 |
2023-08-12 |
Not clear |
| Y Asahi, N Yonehar. Involvement of GABAergic systems in manifestation of pharmacological activity of desipramine. Japanese journal of pharmacology. vol 86. issue 3. 2002-01-02. PMID:11488432. |
in a slice preparation of the hippocampus, treatment with gaba (10(-5)-5 x 10(-4) m), baclofen (10(-5)-10(-4) m) or muscimol (10(-5)-10(-4) m) inhibited the field potential evoked in pyramidal neurons by schaffer collateral stimulation. |
2002-01-02 |
2023-08-12 |
Not clear |