| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T L Whitworth, M W Quic. Upregulation of gamma-aminobutyric acid transporter expression: role of alkylated gamma-aminobutyric acid derivatives. Biochemical Society transactions. vol 29. issue Pt 6. 2002-03-12. PMID:11709066. |
prolonged incubation of hippocampal cultures, which endogenously express gat1, with gabapentin and pregabalin caused a 2-fold increase in subsequent gaba uptake, which was concentration- and time-dependent. |
2002-03-12 |
2023-08-12 |
rat |
| A J McDonald, F Mascagn. Localization of the CB1 type cannabinoid receptor in the rat basolateral amygdala: high concentrations in a subpopulation of cholecystokinin-containing interneurons. Neuroscience. vol 107. issue 4. 2002-03-05. PMID:11720787. |
the intense staining of the cholecystokinin-containing interneurons and the evidence that large amounts of cb1 receptor protein are transported down the axons of these cells suggests that, as in the hippocampus, cannabinoids may inhibit the release of gaba from the axon terminals of these neurons. |
2002-03-05 |
2023-08-12 |
rat |
| C Frahm, A Draguh. GAD and GABA transporter (GAT-1) mRNA expression in the developing rat hippocampus. Brain research. Developmental brain research. vol 132. issue 1. 2002-03-05. PMID:11744102. |
gad and gaba transporter (gat-1) mrna expression in the developing rat hippocampus. |
2002-03-05 |
2023-08-12 |
rat |
| C Frahm, A Draguh. GAD and GABA transporter (GAT-1) mRNA expression in the developing rat hippocampus. Brain research. Developmental brain research. vol 132. issue 1. 2002-03-05. PMID:11744102. |
we therefore analyzed the distribution of mrna coding for gad and gat-1 (the main neuronal gaba transporter) in the developing rat hippocampus. |
2002-03-05 |
2023-08-12 |
rat |
| Sean B Christie, Celia P Miralles, Angel L De Bla. GABAergic innervation organizes synaptic and extrasynaptic GABAA receptor clustering in cultured hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 3. 2002-02-27. PMID:11826098. |
we have studied the effects of gabaergic innervation on the clustering of gaba(a) receptors (gaba(a)rs) in cultured hippocampal neurons. |
2002-02-27 |
2023-08-12 |
Not clear |
| Jonathon P Wetherington, Nevin A Lamber. Differential desensitization of responses mediated by presynaptic and postsynaptic A1 adenosine receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 4. 2002-02-26. PMID:11850452. |
in hippocampal neurons, activation of adenosine a1 receptors (a1rs) or gaba(b) receptors on synaptic terminals inhibits neurotransmitter release, whereas activation of the same receptors on cell bodies and dendrites decreases excitability by activating inwardly rectifying potassium (girk) channels. |
2002-02-26 |
2023-08-12 |
Not clear |
| C Casasola, J Bargas, J A Arias-Montaño, E Calixto, T Montiel, E Galarraga, S Brailowsk. Hippocampal hyperexcitability induced by GABA withdrawal is due to down-regulation of GABA(A) receptors. Epilepsy research. vol 47. issue 3. 2002-02-22. PMID:11738933. |
hippocampal hyperexcitability induced by gaba withdrawal is due to down-regulation of gaba(a) receptors. |
2002-02-22 |
2023-08-12 |
Not clear |
| C Casasola, J Bargas, J A Arias-Montaño, E Calixto, T Montiel, E Galarraga, S Brailowsk. Hippocampal hyperexcitability induced by GABA withdrawal is due to down-regulation of GABA(A) receptors. Epilepsy research. vol 47. issue 3. 2002-02-22. PMID:11738933. |
it is concluded that, in the ca1 region of the hippocampus, it is the number of functional gaba(a) receptors, and not the affinity of the receptor, what is decreased during gw-induced hyperexcitability. |
2002-02-22 |
2023-08-12 |
Not clear |
| Ina Brünig, Eleonora Scotti, Corinne Sidler, Jean-Marc Fritsch. Intact sorting, targeting, and clustering of gamma-aminobutyric acid A receptor subtypes in hippocampal neurons in vitro. The Journal of comparative neurology. vol 443. issue 1. 2002-02-21. PMID:11793346. |
intact sorting, targeting, and clustering of gamma-aminobutyric acid a receptor subtypes in hippocampal neurons in vitro. |
2002-02-21 |
2023-08-12 |
rat |
| Ina Brünig, Eleonora Scotti, Corinne Sidler, Jean-Marc Fritsch. Intact sorting, targeting, and clustering of gamma-aminobutyric acid A receptor subtypes in hippocampal neurons in vitro. The Journal of comparative neurology. vol 443. issue 1. 2002-02-21. PMID:11793346. |
the cellular and subcellular distribution of four gaba(a) receptor subtypes, identified by the presence of the alpha1, alpha2, alpha3, or alpha5 subunit, was investigated immunocytochemically in dissociated cultures of hippocampal neurons. |
2002-02-21 |
2023-08-12 |
rat |
| Catherine H Gill, Ellen M Soffin, Jim J Hagan, Ceri H Davie. 5-HT7 receptors modulate synchronized network activity in rat hippocampus. Neuropharmacology. vol 42. issue 1. 2002-02-20. PMID:11750918. |
in the ca3 region of rat hippocampal slices gamma-amino-butyric acid (gaba)(a/b) receptor antagonists induce low frequency bursting activity that was either inhibited (in 21% of slices) or increased by the selective 5-ht receptor agonists 5-carboxy-tryptamine (0.1-1 microm) and 8-hydroxydipropylaminotetralin (8-oh-dpat). |
2002-02-20 |
2023-08-12 |
rat |
| M V Jones, P Jonas, Y Sahara, G L Westbroo. Microscopic kinetics and energetics distinguish GABA(A) receptor agonists from antagonists. Biophysical journal. vol 81. issue 5. 2002-02-19. PMID:11606279. |
to test this idea, we developed a novel deconvolution-based method to compare binding and unbinding kinetics of gaba(a) receptor agonists and antagonists in outside-out patches from rat hippocampal neurons. |
2002-02-19 |
2023-08-12 |
rat |
| J Vela, J Vitorica, D Ruan. Rapid PCR-mediated synthesis of competitor molecules for accurate quantification of beta(2) GABA(A) receptor subunit mRNA. Brain research. Brain research protocols. vol 8. issue 3. 2002-02-19. PMID:11733194. |
finally, using this method we have been able to quantify the increase in the expression of the beta(2) gaba(a) receptor subunit mrna that occurs during rat hippocampus development. |
2002-02-19 |
2023-08-12 |
rat |
| A Degroot, M B Paren. Infusions of physostigmine into the hippocampus or the entorhinal cortex attenuate avoidance retention deficits produced by intra-septal infusions of the GABA agonist muscimol. Brain research. vol 920. issue 1-2. 2002-02-07. PMID:11716806. |
infusions of physostigmine into the hippocampus or the entorhinal cortex attenuate avoidance retention deficits produced by intra-septal infusions of the gaba agonist muscimol. |
2002-02-07 |
2023-08-12 |
rat |
| A Degroot, M B Paren. Infusions of physostigmine into the hippocampus or the entorhinal cortex attenuate avoidance retention deficits produced by intra-septal infusions of the GABA agonist muscimol. Brain research. vol 920. issue 1-2. 2002-02-07. PMID:11716806. |
we suggest that high levels of septal gaba receptor activity might impair memory by down-regulating ach levels in the hippocampal region, and that such memory impairments can be ameliorated by increasing ach levels in the hippocampus or entorhinal cortex. |
2002-02-07 |
2023-08-12 |
rat |
| Q Cheng, P M Burkat, J C Kulli, J Yan. GABA(C) rho(1) subunits form functional receptors but not functional synapses in hippocampal neurons. Journal of neurophysiology. vol 86. issue 5. 2002-02-06. PMID:11698546. |
gaba(c) rho(1) subunits form functional receptors but not functional synapses in hippocampal neurons. |
2002-02-06 |
2023-08-12 |
Not clear |
| Q Cheng, P M Burkat, J C Kulli, J Yan. GABA(C) rho(1) subunits form functional receptors but not functional synapses in hippocampal neurons. Journal of neurophysiology. vol 86. issue 5. 2002-02-06. PMID:11698546. |
we designed a recombinant adenovirus to deliver either a gaba(c) receptor rho(1) subunit or a mutant gaba(a) receptor beta(2) subunit lacking picrotoxin sensitivity [beta2(mut)] to hippocampal neurons. |
2002-02-06 |
2023-08-12 |
Not clear |
| Q Cheng, P M Burkat, J C Kulli, J Yan. GABA(C) rho(1) subunits form functional receptors but not functional synapses in hippocampal neurons. Journal of neurophysiology. vol 86. issue 5. 2002-02-06. PMID:11698546. |
whole cell patch-clamp recordings demonstrated somatic expression of both bicuculline-resistant gaba(c) receptor-mediated and picrotoxin-resistant gaba(a) receptor-mediated gaba-evoked currents in rho(1)- and beta(2)(mut)-transduced hippocampal neurons, respectively. |
2002-02-06 |
2023-08-12 |
Not clear |
| Jingyi Ma, Bixia Shen, Lee S Stewart, Ian A Herrick, L Stan Leun. The septohippocampal system participates in general anesthesia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 2. 2002-01-30. PMID:11784812. |
in the awake, freely behaving rat, inactivation of the medial septum or the hippocampus by local injection of a gaba(a) receptor agonist, muscimol, decreased the dose of a general anesthetic needed to induce a loss of the tail-pinch response or a loss of righting reflex. |
2002-01-30 |
2023-08-12 |
rat |
| T Bast, W N Zhang, J Feldo. Hyperactivity, decreased startle reactivity, and disrupted prepulse inhibition following disinhibition of the rat ventral hippocampus by the GABA(A) receptor antagonist picrotoxin. Psychopharmacology. vol 156. issue 2-3. 2002-01-28. PMID:11549225. |
hyperactivity, decreased startle reactivity, and disrupted prepulse inhibition following disinhibition of the rat ventral hippocampus by the gaba(a) receptor antagonist picrotoxin. |
2002-01-28 |
2023-08-12 |
rat |