| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiamou Ren, Shuli Zhang, Xiaoling Wang, Yuxin Deng, Yi Zhao, Yan Xiao, Jian Liu, Liangzhao Chu, Xiaolan Q. MEF2C ameliorates learning, memory, and molecular pathological changes in Alzheimer's disease and. Acta biochimica et biophysica Sinica. vol 54. issue 1. 2022-02-07. PMID:35130621. |
in addition, knockdown of enhances the generation and aggregation of aβ in the cortex of app/ps1_dt mice, reduces the expression of synaptic proteins, exacerbates the ability of learning and memory of app/ps1_dt mice, damages the structure of mitochondria, increases the oxidative stress (os) level, and inhibits the expression levels of members of the nrf2-are signal pathway. |
2022-02-07 |
2023-08-13 |
mouse |
| Mariana Angoa-Pérez, John H Anneken, Donald M Kuh. The Role of Brain-Derived Neurotrophic Factor in the Pathophysiology of Psychiatric and Neurological Disorders. Journal of psychiatry and psychiatric disorders. vol 1. issue 5. 2022-01-31. PMID:35098038. |
bdnf is highly expressed in limbic structures and cerebral cortex, making it a crucial factor in the regulation of learning and memory, affective behaviors and reward processes. |
2022-01-31 |
2023-08-13 |
human |
| Xiaoyan Du, Lianzhong Luo, Qingyu Huang, Jie Zhan. Cortex metabolome and proteome analysis reveals chronic arsenic exposure via drinking water induces developmental neurotoxicity through hnRNP L mediated mitochondrial dysfunction in male rats. The Science of the total environment. 2022-01-25. PMID:35074374. |
thus, this study aimed to explore the molecular mechanisms of arsenic-induced learning and memory function impairments through the integrative proteome and metabolome analysis of cortex in rats. |
2022-01-25 |
2023-08-13 |
rat |
| Hyunha Kim, Min Jae Kim, Young Woo Kwon, Sangheon Jeon, Seo-Yeon Lee, Chang-Seok Kim, Byung Tae Choi, Yong-Il Shin, Suck Won Hong, Hwa Kyoung Shi. Benefits of a Skull-Interfaced Flexible and Implantable Multilight Emitting Diode Array for Photobiomodulation in Ischemic Stroke. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2022-01-25. PMID:35076161. |
moreover, the pbm with 630 nm led array remarkably improves the capability of spatial learning and memory in the chronic poststroke phase, attenuates aim2 inflammasome activation and inflammasome-mediated pyroptosis, and modulates microglial polarization in the hippocampus and cortex 7 days following ischemic stroke. |
2022-01-25 |
2023-08-13 |
mouse |
| Sydney Trask, Fred J Helmstette. Unique Roles for the Anterior and Posterior Retrosplenial Cortices in Encoding and Retrieval of Memory for Context. Cerebral cortex (New York, N.Y. : 1991). 2022-01-14. PMID:35029643. |
the rat retrosplenial cortex (rsc) makes critical contributions to learning and memory but these contributions may not be uniform along its rostro-caudal axis. |
2022-01-14 |
2023-08-13 |
rat |
| Vivek Verma, Ruchika Kumari, Muniyandi Singarave. Chronic altered light-dark cycle differentially affects hippocampal CA1 and DG neuronal arborization in diurnal and nocturnal rodents. Chronobiology international. 2022-01-05. PMID:34983277. |
the hippocampus, an extension of the temporal part of the cerebral cortex, plays a crucial role in learning and memory. |
2022-01-05 |
2023-08-13 |
Not clear |
| Weifeng Shan, Yini Wu, Xin Han, Qin Chen, Jimin W. The mechanism of sevoflurane post-treatment alleviating hypoxic-ischemic encephalopathy by affecting histone methyltransferase G9a in rats. Bioengineered. vol 12. issue 2. 2021-12-08. PMID:34672892. |
after sf post-treatment, the neurons in cerebral cortex, the learning and memory skills and the contents of ngf/bdnf were increased, while the apoptosis and g9a/h3k9me2 levels were reduced. |
2021-12-08 |
2023-08-13 |
rat |
| Susan Zhou, Zhengping Ji. Disruption of PAK3 Signaling in Social Interaction Induced cFos Positive Cells Impairs Social Recognition Memory. Cells. vol 10. issue 11. 2021-12-08. PMID:34831234. |
we show that the expression of mpak3-gfp proteins was in cfos-expressing excitatory and inhibitory neurons in various brain regions, such as the cortex and hippocampus, commonly activated during learning and memory. |
2021-12-08 |
2023-08-13 |
mouse |
| Bo-Wen Chen, Kai-Wen Zhang, Si-Jia Chen, Chun Yang, Peng-Gao L. Vitamin A Deficiency Exacerbates Gut Microbiota Dysbiosis and Cognitive Deficits in Amyloid Precursor Protein/Presenilin 1 Transgenic Mice. Frontiers in aging neuroscience. vol 13. 2021-11-19. PMID:34790112. |
our results show that vad aggravated the behavioral learning and memory deficits, reduced the retinol concentration in the liver and the serum, decreased the transcription of vitamin a (va)-related receptors and va-related enzymes in the cortex, increased amyloid-β peptides (aβ40 and aβ42) in the brain and gut, upregulate the translation of beta-site app-cleaving enzyme 1 (bace1) and phosphorylated tau in the cortex, and downregulate the expression of brain-derived neurotrophic factor (bdnf) and γ-aminobutyric acid (gaba) receptors in the cortex. |
2021-11-19 |
2023-08-13 |
mouse |
| Dylan C Sarver, Cheng Xu, Yi Cheng, Chantelle E Terrillion, G William Won. CTRP4 ablation impairs associative learning and memory. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 35. issue 11. 2021-11-12. PMID:34610176. |
this deficit is sex-dependent, affects only female mice, and is associated with altered expression of learning and memory genes (arc, c-fos, and pde4d) in the hippocampus and cortex. |
2021-11-12 |
2023-08-13 |
mouse |
| Clare R Quirk, Ipshita Zutshi, Sunandha Srikanth, Maylin L Fu, Naomie Devico Marciano, Morgan K Wright, Darian F Parsey, Stanley Liu, Rachel E Siretskiy, Tiffany L Huynh, Jill K Leutgeb, Stefan Leutge. Precisely timed theta oscillations are selectively required during the encoding phase of memory. Nature neuroscience. vol 24. issue 11. 2021-11-10. PMID:34608335. |
the entorhinal cortex and hippocampus are necessary for learning and memory and exhibit prominent theta oscillations (6-9 hz), which are controlled by pacemaker cells in the medial septal area. |
2021-11-10 |
2023-08-13 |
mouse |
| Hongmei Ning, Chong Li, Zhihong Yin, Dongfang Hu, Yaming Ge, Lingli Che. Fluoride exposure decreased neurite formation on cerebral cortical neurons of SD rats in vitro. Environmental science and pollution research international. vol 28. issue 37. 2021-09-24. PMID:33977427. |
our previous study showed that fluoride could induce the structural damages of the cerebral cortex and reduce the learning and memory abilities of mice offspring. |
2021-09-24 |
2023-08-13 |
mouse |
| Xiaoyu Wang, Naiqi Shi, Meiqi Hui, Hui Jin, Shumei Gao, Qiao Zhou, Li Zhang, Meijuan Yan, Hongmei She. The Impact of β-1,4-Galactosyltransferase V on Microglial Function. Frontiers in cellular neuroscience. vol 15. 2021-09-21. PMID:34539352. |
our previous study revealed that β-1,4-galt v was expressed in the cortex and hippocampus and participated in the recovery of spatial learning and memory in rats with traumatic brain injury. |
2021-09-21 |
2023-08-13 |
rat |
| Yu Feng, Xu Tian, Miao Zhang, Shujie Lo. Treadmill Exercise Reverses the Change of Dendritic Morphology and Activates BNDF-mTOR Signaling Pathway in the Hippocampus and Cerebral Cortex of Ovariectomized Mice. Journal of molecular neuroscience : MN. vol 71. issue 9. 2021-09-07. PMID:34041687. |
a decline of estrogen level leads to spatial learning and memory impairments, which mediated by hippocampus and cortex. |
2021-09-07 |
2023-08-13 |
mouse |
| Bo Liu, Bo Huang, Jie Liu, Jing-Shan Sh. Dendrobium nobile Lindl alkaloid and metformin ameliorate cognitive dysfunction in senescence-accelerated mice via suppression of endoplasmic reticulum stress. Brain research. vol 1741. 2021-09-01. PMID:32380088. |
dnla improved learning and memory impairments, reduced the loss of neurons and nissl bodies in the hippocampus and cortex. |
2021-09-01 |
2023-08-13 |
mouse |
| Ashley N Opalka, Dong V Wan. Hippocampal efferents to retrosplenial cortex and lateral septum are required for memory acquisition. Learning & memory (Cold Spring Harbor, N.Y.). vol 27. issue 8. 2021-08-17. PMID:32669386. |
learning and memory involves a large neural network of many brain regions, including the notable hippocampus along with the retrosplenial cortex (rsc) and lateral septum (ls). |
2021-08-17 |
2023-08-13 |
mouse |
| Changhong Ren, Yuanyuan Liu, Christopher Stone, Ning Li, Sijie Li, Haiyan Li, Zichao Cheng, Jiangnan Hu, Weiguang Li, Kunlin Jin, Xunming Ji, Yuchuan Din. Limb Remote Ischemic Conditioning Ameliorates Cognitive Impairment in Rats with Chronic Cerebral Hypoperfusion by Regulating Glucose Transport. Aging and disease. vol 12. issue 5. 2021-08-04. PMID:34341702. |
the expression of glut1 and glut3 in the cortex displayed a strong correlation with learning and memory. |
2021-08-04 |
2023-08-13 |
rat |
| Cristina García-Díaz, Isis Gil-Miravet, Hector Albert-Gasco, Aroa Mañas-Ojeda, Francisco Ros-Bernal, Esther Castillo-Gómez, Andrew L Gundlach, Francisco E Olucha-Bordona. Relaxin-3 Innervation From the Nucleus Incertus to the Parahippocampal Cortex of the Rat. Frontiers in neuroanatomy. vol 15. 2021-07-10. PMID:34239421. |
spatial learning and memory processes depend on anatomical and functional interactions between the hippocampus and the entorhinal cortex. |
2021-07-10 |
2023-08-13 |
rat |
| A-X Wei, M-Y Shao, Y Liu, Y Sun, L-M Wang, X-Y Ma, J Mang, Z-X X. Influence of Cilostazol on Changes in Cyclin D1 Expression in Cerebral Cortex of Rats with Chronic Cerebral Ischemia. Physiological research. vol 69. issue 4. 2021-07-08. PMID:32584130. |
the influence of cilostazol on learning and memory, and cyclin d1 expression in the cerebral cortex of rats with chronic cerebral ischemia were investigated. |
2021-07-08 |
2023-08-13 |
rat |
| Xiaojie Zhao, Kelly Wilson, Victor Uteshev, Johnny J H. Activation of α7 nicotinic acetylcholine receptor ameliorates HIV-associated neurology and neuropathology. Brain : a journal of neurology. 2021-07-01. PMID:34196664. |
we showed that pnu-125096 treatment significantly improved locomotor, learning and memory deficits of itat mice while inhibited glial activation and increased psd-95 expression in the cortex and hippocampus of itat mice. |
2021-07-01 |
2023-08-13 |
mouse |