| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Youngnam Kang, Hiroki Toyoda, Mitsuru Sait. Search for unknown neural link between the masticatory and cognitive brain systems to clarify the involvement of its impairment in the pathogenesis of Alzheimer's disease. Frontiers in cellular neuroscience. vol 18. 2024-07-12. PMID:38994328. |
on the other hand, a large number of epidemiological studies have shown that tooth loss or masticatory dysfunction is a risk factor for dementia including ad, and numerous studies using experimental animals have also shown that masticatory dysfunction causes brain degeneration in the basal forebrain, hippocampus, and cerebral cortex similar to those observed in human ad, and that learning and memory functions are impaired accordingly. |
2024-07-12 |
2024-07-14 |
human |
| Han Yin Cheng, Danielle I Fournier, Travis P Tod. Retrosplenial cortex and aversive conditioning. Frontiers in behavioral neuroscience. vol 18. 2024-07-10. PMID:38983870. |
the retrosplenial cortex (rsc) is well-known for its contribution to episodic memory, as well as contextual and spatial learning and memory. |
2024-07-10 |
2024-07-12 |
Not clear |
| Honqiao Wei, Xiaokun Wang, Hequan Zhong, Xiangyu Kong, Jie Zhu, Bing L. Artesunate improves learning and memory impairment in rats with vascular cognitive impairment by down-regulating the level of autophagy in cerebral cortex neurons. Heliyon. vol 10. issue 12. 2024-07-01. PMID:38948049. |
artesunate improves learning and memory impairment in rats with vascular cognitive impairment by down-regulating the level of autophagy in cerebral cortex neurons. |
2024-07-01 |
2024-07-03 |
rat |
| Honqiao Wei, Xiaokun Wang, Hequan Zhong, Xiangyu Kong, Jie Zhu, Bing L. Artesunate improves learning and memory impairment in rats with vascular cognitive impairment by down-regulating the level of autophagy in cerebral cortex neurons. Heliyon. vol 10. issue 12. 2024-07-01. PMID:38948049. |
this study to investigate whether artesunate (art) can improve the learning and memory function in rats with vci by down-regulating he level of autophagy in cerebral cortex neurons. |
2024-07-01 |
2024-07-03 |
rat |
| Yaya Zhang, Na Pang, Xiaowei Huang, Wen Meng, Long Meng, Bingchang Zhang, Zhengye Jiang, Jing Zhang, Zhou Yi, Zhiyu Luo, Zhanxiang Wang, Lili Ni. Ultrasound deep brain stimulation decelerates telomere shortening in Alzheimer's disease and aging mice. Fundamental research. vol 3. issue 3. 2024-06-27. PMID:38933758. |
then, in the alzheimer's disease mice, udbs was observed to decelerate telomere shortening of the cortex and myocardial tissue and to effectively improve spatial learning and memory abilities. |
2024-06-27 |
2024-06-29 |
mouse |
| Paul A S Sheppard, Charlotte A Oomen, Timothy J Bussey, Lisa M Saksid. The granular retrosplenial cortex is necessary in male rats for object-location associative learning and memory, but not spatial working memory or visual discrimination and reversal, in the touchscreen operant chamber. eNeuro. 2024-06-06. PMID:38844347. |
the granular retrosplenial cortex is necessary in male rats for object-location associative learning and memory, but not spatial working memory or visual discrimination and reversal, in the touchscreen operant chamber. |
2024-06-06 |
2024-06-10 |
human |
| Hyo-Sun Choi, Joonki Kim, Sang-Bin Lee, Lijun Zhang, Dowan Kwon, Huynh Nguyen Khanh Tran, Siqi Zhang, Tianqi Huang, Jae Sik Yu, Gakyung Lee, Hyun Ok Yan. Euonymus hamiltonianus Extract Improves Amnesia in APPswe/Tau Transgenic and Scopolamine-Induced Dementia Models. Molecular neurobiology. 2024-05-27. PMID:38801629. |
kgc07eh also improved scopolamine-induced learning and memory impairment in scopolamine-injected mice, and in their cerebral cortex and hippocampus, the expression levels of p-erk, p-creb, p-akt, and bdnf were attenuated. |
2024-05-27 |
2024-05-31 |
mouse |
| Aysegul Gungor Aydin, Alexander Lemenze, Kasia M Bieszcza. Functional diversities within neurons and astrocytes in the adult rat auditory cortex revealed by single-nucleus RNA sequencing. bioRxiv : the preprint server for biology. 2024-04-25. PMID:38659766. |
together, these results pave the way for building models of how neurons in the sensory cortex work in concert with astrocytes at synapses to fulfill high-cognitive functions like learning and memory. |
2024-04-25 |
2024-04-28 |
rat |
| Ji-Yong Liu, Wen-Li Zhang, Jun Liao, Li-Juan Hu, Guo-Zuo Wang, Jin-Wen Ge, Zhi-Gang Me. [Effect of Naotaifang on microglial polarization and glial scar following cerebral ischemia reperfusion injury]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 4. 2024-04-15. PMID:38621906. |
compared with the sham, model 7 d and model 14 d groups showed cerebral infarction of different degrees, severe pathological injury of cerebral cortex and hippocampus, neurological impairment, reduced spatial learning and memory, cognitive dysfunction, severe anxiety, astrocyte hyperplasia, thickening penumbra glial scar, and up-regulated protein levels of il-1β, il-6, gfap, neurocan, phosphacan, cd206, and arg-1(p<0.01). |
2024-04-15 |
2024-04-18 |
rat |
| Kushagra Nagori, Madhulika Pradhan, Mukesh Sharma, Ajazuddin, Hemant R Badwaik, Kartik T Nakhat. Current Progress on Central Cholinergic Receptors as Therapeutic Targets for Alzheimer's Disease. Current Alzheimer research. 2024-03-26. PMID:38529600. |
by modulating synaptic transmission and promoting synaptic plasticity, particularly in the hippocampus and cortex, ach plays a pivotal role in the regulation of learning and memory. |
2024-03-26 |
2024-03-28 |
Not clear |
| Qingquan Li, Xiaokui Gan, Ming Zhang, Guangmin Zhang, Yingbin Li, Liang Ga. Erianin promotes endogenous neurogenesis in traumatic brain injury rats. Scientific reports. vol 14. issue 1. 2024-02-19. PMID:38374284. |
additionally, there was an increase in neuronal regeneration in the cortex and hippocampus, inhibition of pro-inflammatory microglial cell transformation in the cortex, improvement in learning and memory function in tbi rats, and simultaneous inhibition of the activation of the erk1/c-jun signal pathway. |
2024-02-19 |
2024-02-22 |
rat |
| Pia Kruse, Gudrun Brandes, Hanna Hemeling, Zhong Huang, Christoph Wrede, Jan Hegermann, Andreas Vlachos, Maximilian Len. Synaptopodin Regulates Denervation-Induced Plasticity at Hippocampal Mossy Fiber Synapses. Cells. vol 13. issue 2. 2024-01-22. PMID:38247806. |
in order to address this issue, we performed an entorhinal cortex lesion (ecl) in mouse organotypic entorhino-hippocampal tissue cultures of both sexes and studied denervation-induced plasticity of mossy fiber synapses, which connect dentate granule cells (dgcs) with ca3 pyramidal cells (ca3-pcs) and play important roles in learning and memory formation. |
2024-01-22 |
2024-01-24 |
mouse |
| Xi Zhang, Hong Zheng, Zhitao Ni, Yuyin Shen, Die Wang, Wenqing Li, Liangcai Zhao, Chen Li, Hongchang Ga. Fibroblast growth factor 21 alleviates diabetes-induced cognitive decline. Cerebral cortex (New York, N.Y. : 1991). 2024-01-14. PMID:38220573. |
results revealed that i.c.v fgf21 infusion effectively improved learning and memory performance of dicd mice; neuron loss and apoptosis in hippocampus and cortex were significantly blocked, suggesting a potential neuroprotective role of fgf21 in dicd. |
2024-01-14 |
2024-01-17 |
mouse |
| Jingjing Ge, Xiaoling Jiao, Hui L. MicroRNA-126-3P targets PIK3R2 to ameliorate autophagy and apoptosis of cortex in hypoxia-reoxygenation treated neonatal rats. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 12. 2023-12-08. PMID:38063094. |
injection of mir-126-3p mimic raised the learning and memory abilities through down-regulating the cerebral ischemic area, improving pathological damage of the cortex, reducing the neurons apoptosis of the cortex and down-regulating the autophagy-related and apoptosis-related proteins. |
2023-12-08 |
2023-12-17 |
rat |
| Clark W Bird, Stefanie S Mayfield, Katalina M Lopez, Brooke R Dunn, Angela Feng, Bryce T Roberts, Roberto N Almeida, Glenna J Chavez, C Fernando Valenzuel. Binge-like ethanol exposure during the brain growth spurt disrupts the function of retrosplenial cortex-projecting anterior thalamic neurons in adolescent mice. Neuropharmacology. 2023-10-01. PMID:37778437. |
ethanol (etoh) exposure during late pregnancy leads to enduring impairments in learning and memory that may stem from damage to components of the posterior limbic memory system, including the retrosplenial cortex (rsc) and anterior thalamic nuclei (atn). |
2023-10-01 |
2023-10-07 |
mouse |
| Qihui Zhao, Junli Chen, Mengjun Wu, Xiaoli Yin, Qiaoying Jiang, Hongchang Gao, Hong Zhen. Microbiota from healthy mice alleviates cognitive decline via reshaping the gut-brain metabolic axis in diabetic mice. Chemico-biological interactions. 2023-07-20. PMID:37473910. |
the results demonstrate that fmt from healthy mice effectively improved the learning and memory abilities in t1d mice, and significantly reduced neuroinflammation and neuron injury in the cortex and hippocampus. |
2023-07-20 |
2023-08-14 |
mouse |
| Qingxi Zhang, Qingrui Duan, Yuyuan Gao, Peikun He, Rui Huang, Haifeng Huang, Yanyi Li, Guixian Ma, Yuhu Zhang, Kun Nie, Lijuan Wan. Cerebral Microvascular Injury Induced by Lag3-Dependent α-Synuclein Fibril Endocytosis Exacerbates Cognitive Impairment in a Mouse Model of α-Synucleinopathies. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2023-06-29. PMID:37381656. |
here, it is reported that combined injection of α-syn preformed fibrils (pffs) in the unilateral substantia nigra pars compacta, hippocampus, and cerebral cortex results in impaired spatial learning and memory abilities at 6 months post-injection and that this cognitive decline is related to cerebral microvascular injury. |
2023-06-29 |
2023-08-14 |
mouse |
| Shogo Soma, Shinya Ohara, Satoshi Nonomura, Naofumi Suematsu, Junichi Yoshida, Eva Pastalkova, Yutaka Sakai, Ken-Ichiro Tsutsui, Yoshikazu Isomur. Rat hippocampal CA1 region represents learning-related action and reward events with shorter latency than the lateral entorhinal cortex. Communications biology. vol 6. issue 1. 2023-05-31. PMID:37258700. |
the hippocampus and entorhinal cortex are deeply involved in learning and memory. |
2023-05-31 |
2023-08-14 |
rat |
| Priyanka De, Kunal Ro. Computational modeling of PET imaging agents for vesicular acetylcholine transporter (VAChT) protein binding affinity: application of 2D-QSAR modeling and molecular docking techniques. In silico pharmacology. vol 11. issue 1. 2023-04-10. PMID:37035236. |
the neurotransmitter acetylcholine (ach) plays a ubiquitous role in cognitive functions including learning and memory with widespread innervation in the cortex, subcortical structures, and the cerebellum. |
2023-04-10 |
2023-08-14 |
Not clear |
| Bente Jacobsen, Heidi Kleven, Wairimu Gatome, Liora Las, Nachum Ulanovsky, Menno P Witte. Organization of projections from the entorhinal cortex to the hippocampal formation of the Egyptian fruit bat Rousettus aegyptiacus. Hippocampus. 2023-03-04. PMID:36869437. |
the hippocampal formation and entorhinal cortex are crucially involved in learning and memory as well as in spatial navigation. |
2023-03-04 |
2023-08-14 |
Not clear |