| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michalina Hanzel, Kayla Fernando, Susan E Maloney, Shioaching Gong, Kärt Mätlik, Jiajia Zhao, H Amalia Pasolli, Søren Heissel, Joseph D Dougherty, Court Hull, Mary E Hatte. Mice lacking bioRxiv : the preprint server for biology. 2024-02-26. PMID:38405978. |
mice lacking astrotactin 2 (astn2) is a transmembrane neuronal protein highly expressed in the cerebellum that functions in receptor trafficking and modulates cerebellar purkinje cell (pc) synaptic activity. |
2024-02-26 |
2024-02-28 |
mouse |
| Ping He, Shuting Zhong, Shuaijun Lin, Zhiyan Xia, Liqing Wang, Yuhe Han, Di Xu, Shuping Hu, Xiaokun Li, Peijun Li, Cong Wan. FGF9 is required for Purkinje cell development and function in the cerebellum. iScience. vol 27. issue 2. 2024-02-14. PMID:38352230. |
fgf9 is required for purkinje cell development and function in the cerebellum. |
2024-02-14 |
2024-02-16 |
Not clear |
| Ping He, Shuting Zhong, Shuaijun Lin, Zhiyan Xia, Liqing Wang, Yuhe Han, Di Xu, Shuping Hu, Xiaokun Li, Peijun Li, Cong Wan. FGF9 is required for Purkinje cell development and function in the cerebellum. iScience. vol 27. issue 2. 2024-02-14. PMID:38352230. |
it has been reported that deletion of fgf9 leads to defects in cerebellum development, including purkinje cell defect. |
2024-02-14 |
2024-02-16 |
Not clear |
| Smathorn Thakolwiboon, Jenny Linnoila, Sean J Pittock, Divyanshu Dubey, Anastasia Zekerido. Cerebellar leptomeningeal enhancement: An imaging finding of rapidly progressive Purkinje cell cytoplasmic autoantibody type 1 paraneoplastic cerebellar syndrome. Journal of neuroimmunology. vol 387. 2024-01-24. PMID:38266443. |
cerebellar leptomeningeal enhancement: an imaging finding of rapidly progressive purkinje cell cytoplasmic autoantibody type 1 paraneoplastic cerebellar syndrome. |
2024-01-24 |
2024-01-27 |
Not clear |
| Smathorn Thakolwiboon, Jenny Linnoila, Sean J Pittock, Divyanshu Dubey, Anastasia Zekerido. Cerebellar leptomeningeal enhancement: An imaging finding of rapidly progressive Purkinje cell cytoplasmic autoantibody type 1 paraneoplastic cerebellar syndrome. Journal of neuroimmunology. vol 387. 2024-01-24. PMID:38266443. |
purkinje cell cytoplasmic autoantibody type 1 (pca1), also known as anti-yo, is a 'high-risk' paraneoplastic antibody, associated with rapidly progressive cerebellar syndrome. |
2024-01-24 |
2024-01-27 |
Not clear |
| Samar M Ez Elarab, Mohamed A M Alsafy, Samir A A El-Gendy, Neveen E R El-Bakary, Ahmed Elsayed Noreldin, Ahmed M Rashwa. Investigating the role of Purkinje fibers and synaptic connectivity in balance regulation through comprehensive ultrastructural and immunohistochemical analysis of the donkey's (Equus asinus) cerebellum. Journal of experimental zoology. Part A, Ecological and integrative physiology. 2024-01-17. PMID:38229259. |
the purkinje cells were situated in the intermediate zone of the cerebellum cortex, known as the purkinje cell layer. |
2024-01-17 |
2024-01-19 |
Not clear |
| Sara A Hosny, Alshaymaa M Abdelmenem, Taha Azouz, Samaa S Kamar, Asmaa M ShamsEldeen, Asmaa A El-Shafe. Beneficial Effect of Erythropoietin on Ameliorating Propionic Acid-Induced Autistic-Like Features in Young Rats. Acta histochemica et cytochemica. vol 56. issue 5. 2023-11-16. PMID:37970239. |
epo protected cerebellar structure, increased purkinje cell count, improved neuronal morphology, reduced ppa-induced autistic-like features, alleviated neuronal oxidative stress, increased intercellular antioxidant levels, and suppressed inflammation. |
2023-11-16 |
2023-11-20 |
rat |
| Christopher H Chen, Leannah N Newman, Amanda P Stark, Katherine E Bond, Dawei Zhang, Stefano Nardone, Charles R Vanderburg, Naeem M Nadaf, Zhiyi Yao, Kefiloe Mutume, Isabella Flaquer, Bradford B Lowell, Evan Z Macosko, Wade G Regeh. A Purkinje cell to parabrachial nucleus pathway enables broad cerebellar influence over the forebrain. Nature neuroscience. vol 26. issue 11. 2023-11-03. PMID:37919612. |
a purkinje cell to parabrachial nucleus pathway enables broad cerebellar influence over the forebrain. |
2023-11-03 |
2023-11-08 |
Not clear |
| Lan Zhang, Kun Yang, Xiao Tan, Yazhu Cai, Haie Ding, Rui Li, Yiyang Zhang, Manlin Zhou, Zuli Ben, Qian Zhang, Zilin Qia. Analysis of age-related differences in hypoxia-related factors in yak brain tissue. Folia morphologica. 2023-10-12. PMID:37822067. |
immunohistochemical results showed that hif-1α, epo, vegf, and vcam were expressed in the pyramidal cell layer of the yak cerebrum, and distributed in the cerebellum granulose cell layer, purkinje cell layer and medulla layer, and were mainly positive in purkinje cells and medulla. |
2023-10-12 |
2023-10-15 |
Not clear |
| Seth A Ament, Marcia Cortes-Gutierrez, Brian R Herb, Evelina Mocci, Carlo Colantuoni, Margaret M McCarth. A single-cell genomic atlas for maturation of the human cerebellum during early childhood. Science translational medicine. 2023-10-12. PMID:37824600. |
immunohistochemical analysis of a subset of these postmortem cerebellar samples revealed no change to purkinje neuron soma size but evidence for increased activation of microglia in those children who had experienced inflammation. |
2023-10-12 |
2023-10-15 |
human |
| Owen Y Chao, Salil Saurav Pathak, Hao Zhang, George J Augustine, Jason M Christie, Chikako Kikuchi, Hiroki Taniguchi, Yi-Mei Yan. Social memory deficit caused by dysregulation of the cerebellar vermis. Nature communications. vol 14. issue 1. 2023-09-26. PMID:37752149. |
we selectively increased the excitability of molecular layer interneurons (mlis) to suppress purkinje cell firing in the mouse cerebellar vermis. |
2023-09-26 |
2023-10-07 |
mouse |
| Franziska Auer, Katherine Nardone, Koji Matsuda, Masahiko Hibi, David Schoppi. Purkinje Cells Control Posture in Larval Zebrafish ( bioRxiv : the preprint server for biology. 2023-09-25. PMID:37745506. |
moreover, by comparing the contributions of purkinje cell ablations to posture in time, we uncover signatures of emerging cerebellar control of posture across early development. |
2023-09-25 |
2023-10-07 |
zebrafish |
| Youngyun Jin, Taewan Kim, Taewoon Ki. Effect of Physical Exercise on Mitochondrial Dysfunction and Purkinje Cell Survival in the Cerebellum of 3xTg-AD Mice. Journal of integrative neuroscience. vol 22. issue 5. 2023-09-21. PMID:37735133. |
effect of physical exercise on mitochondrial dysfunction and purkinje cell survival in the cerebellum of 3xtg-ad mice. |
2023-09-21 |
2023-10-07 |
mouse |
| Soyoung Jun, Muwoong Kim, Heeyoun Park, Eunmi Hwang, Yukio Yamamoto, Keiko Tanaka-Yamamot. Organization of Purkinje cell development by neuronal MEGF11 in cerebellar granule cells. Cell reports. vol 42. issue 9. 2023-09-14. PMID:37708022. |
megf11-kd in gcs of developing mice results in abnormal cerebellar structures, including extensively ectopic purkinje cell (pc) somas, and in impaired motor functions. |
2023-09-14 |
2023-10-07 |
mouse |
| Yu-Young Tsai, Chiu-Lun Shen, Dhananjaya D, Ching-Yen Tsai, Woan-Yuh Tar. Activation of TrkB signaling mitigates cerebellar anomalies caused by Rbm4-Bdnf deficiency. Communications biology. vol 6. issue 1. 2023-09-05. PMID:37670183. |
finally, prenatal supplementation with 7,8-dihydroxyflavone, a trkb agonist, restored granule cell differentiation, purkinje cell dendritic complexity and foliation-the intercrural fissure in particular-in the neonatal cerebellum of rbm4dko mice, which also showed improved motor learning in adulthood. |
2023-09-05 |
2023-10-07 |
mouse |
| Chao Li, Han Zhang, Kexin Tong, Menghua Cai, Fei Gao, Jia Yang, Yi Xu, Huaishan Wang, Hui Chen, Yu Hu, Wei He, Jianmin Zhan. Genetic Deletion of Thorase Causes Purkinje Cell Loss and Impaired Motor Coordination Behavior. Cells. vol 12. issue 16. 2023-08-26. PMID:37626842. |
thorase deletion resulted in more purkinje neuron apoptosis, leading to purkinje cell loss in the cerebellum of thorase cko mice. |
2023-08-26 |
2023-09-07 |
mouse |
| David J Herzfeld, Mati Joshua, Stephen G Lisberge. Rate versus synchrony codes for cerebellar control of motor behavior. Neuron. vol 111. issue 15. 2023-08-03. PMID:37536289. |
simultaneous recordings from purkinje cell pairs in the cerebellum of rhesus macaques reveal how these cells coordinate their activity to drive smooth pursuit eye movements. |
2023-08-03 |
2023-08-14 |
Not clear |
| Silas E Busch, Christian Hanse. Climbing fiber multi-innervation of mouse Purkinje dendrites with arborization common to human. Science (New York, N.Y.). vol 381. issue 6656. 2023-07-27. PMID:37499000. |
canonically, each purkinje cell (pc) in the adult cerebellum receives only one climbing fiber (cf) from the inferior olive. |
2023-07-27 |
2023-08-14 |
mouse |
| Mizuki Kato, Erik De Schutte. Models of Purkinje cell dendritic tree selection during early cerebellar development. PLoS computational biology. vol 19. issue 7. 2023-07-24. PMID:37486917. |
models of purkinje cell dendritic tree selection during early cerebellar development. |
2023-07-24 |
2023-08-14 |
Not clear |
| Yuto Okuno, Kazuto Sakoori, Kyoko Matsuyama, Miwako Yamasaki, Masahiko Watanabe, Kouichi Hashimoto, Takaki Watanabe, Masanobu Kan. PTPδ is a presynaptic organizer for the formation and maintenance of climbing fiber to Purkinje cell synapses in the developing cerebellum. Frontiers in molecular neuroscience. vol 16. 2023-07-10. PMID:37426069. |
ptpδ is a presynaptic organizer for the formation and maintenance of climbing fiber to purkinje cell synapses in the developing cerebellum. |
2023-07-10 |
2023-08-14 |
mouse |