| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H S Swartzwelder, C Ferrari, W W Anderson, W A Wilso. The drug MK-801 attenuates the development, but not the expression, of long-term potentiation and stimulus train-induced bursting in hippocampal slices. Neuropharmacology. vol 28. issue 5. 1989-07-11. PMID:2657480. |
in the present experiment, slices of hippocampus, prepared from rats, were electrically stimulated to produce either long-term potentiation of the ca1 population spike or stimulus train-induced epileptiform bursting in area ca3. |
1989-07-11 |
2023-08-11 |
rat |
| J H Garcia, M L Anderso. Physiopathology of cerebral ischemia. Critical reviews in neurobiology. vol 4. issue 4. 1989-07-10. PMID:2655939. |
several potential culprits have been tried: (1) "energy failure", or depletion of high-energy phosphates, occurs very quickly after ischemia, but energy metabolites recover even in tissues where functional return does not occur; (2) "tissue lactacidosis" enhances ischemic cell necrosis, but this factor is not the indispensable cause of neuronal necrosis because acidosis is minimal or nonexistent under conditions of hypoglycemia and seizures; (3) "impairment of the microcirculation" may be a contributing factor, but such microcirculatory impairment cannot be the initiating event as it is known that irreversible neuronal injury precedes the development of microcirculatory abnormalities; (4) the effects of "excitatory neurotransmitters", especially glutamate, may explain the "delayed neuronal death" or the protracted necrosis of neurons in the ca1 sector of the hippocampus; (5) ionic pump alterations: studies of experimental myocardial ischemia tend to support a contributory role of ca2+ in the aggravation of cell necrosis; however, lack of an experimental model in which steady-state conditions can be maintained has left unresolved the potential participation of calcium ions in ischemic cell necrosis; (6) the same statement, concerning the lack of an experimental model, can be made about the role of free-radical species; oxygen free radicals and superoxides are abundant in the reperfusion stage of ischemic injury, but it is unclear how significant their contribution might be as initiators of ischemic necrosis; and (7) the "ischemic penumbra" is a zone or portion of brain tissue that is sufficiently hypoperfused as to be functionless, but where the cells are likely to recover once normal perfusion is reestablished. |
1989-07-10 |
2023-08-11 |
Not clear |
| P Miu, E Pui. Isoflurane-induced impairment of synaptic transmission in hippocampal neurons. Experimental brain research. vol 75. issue 2. 1989-07-07. PMID:2542074. |
the effects of anaesthetic applications of isoflurane were studied using intracellular recording techniques in 82 ca1 neurons of in vitro hippocampal slice preparations (guinea pigs). |
1989-07-07 |
2023-08-11 |
Not clear |
| H B Michelson, J Kapur, E W Lothma. Reduction of paired pulse inhibition in the CA1 region of the hippocampus by pilocarpine in naive and in amygdala-kindled rats. Experimental neurology. vol 104. issue 3. 1989-07-07. PMID:2721629. |
reduction of paired pulse inhibition in the ca1 region of the hippocampus by pilocarpine in naive and in amygdala-kindled rats. |
1989-07-07 |
2023-08-11 |
rat |
| H B Michelson, J Kapur, E W Lothma. Reduction of paired pulse inhibition in the CA1 region of the hippocampus by pilocarpine in naive and in amygdala-kindled rats. Experimental neurology. vol 104. issue 3. 1989-07-07. PMID:2721629. |
the studies presented here compared the electrophysiologic effects of pilocarpine in vivo in the ca1 region of the hippocampus in naive and amygdala-kindled rats. |
1989-07-07 |
2023-08-11 |
rat |
| F Amenta, C Cavallotti, F Franch, A Ricc. Muscarinic cholinergic receptors in the hippocampus of the aged rat: effects of long-term hydergine administration. Archives internationales de pharmacodynamie et de therapie. vol 297. 1989-06-29. PMID:2730238. |
[3h]-qnb accumulated in the hippocampus of 3 month old rats, primarily in the stratum oriens of the ca1 and ca2 fields, followed in descending order by the molecular layer of granule cells of the dentate gyrus and the ca3 field. |
1989-06-29 |
2023-08-11 |
rat |
| b' Y Hong, K Krnjevi\\xc4\\x8. Serotonin blocks the facilitatory action of muscarinic and nicotinic agents in the hippocampus in vivo. Canadian journal of physiology and pharmacology. vol 67. issue 1. 1989-06-16. PMID:2653594.' |
the inhibitory effect of serotonin, released iontophoretically, on acetylcholine-induced facilitation of population spikes evoked by fimbria-commissural stimulation was studied in the ca1 region of rat hippocampus in vivo. |
1989-06-16 |
2023-08-11 |
rat |
| N Saito, A Kose, A Ito, K Hosoda, M Mori, M Hirata, K Ogita, U Kikkawa, Y Ono, K Igarash. Immunocytochemical localization of beta II subspecies of protein kinase C in rat brain. Proceedings of the National Academy of Sciences of the United States of America. vol 86. issue 9. 1989-06-09. PMID:2654944. |
immunoreactive neurons were present in the anterior olfactory nucleus, olfactory tubercle, amygdaloid complex, caudate-putamen, accumbens nucleus, claustrum, dorsal part of the lateral septal nucleus, ca1 region of the hippocampus, subiculum, medial habenular nucleus, cerebral cortex, nucleus of the spinal tract of the trigeminal nerve, nucleus of the solitary tract, and substantia gelatinosa of the spinal cord. |
1989-06-09 |
2023-08-11 |
rat |
| T Yamamoto, S Shiosaka, M E Whittaker, E L Hertzberg, J I Nag. Gap junction protein in rat hippocampus: light microscope immunohistochemical localization. The Journal of comparative neurology. vol 281. issue 2. 1989-06-02. PMID:2540226. |
the two other patterns observed included intense filamentous immunostaining within a small number of neuronal perikarya located mainly in the stratum pyramidale of areas ca2 and ca3, but rarely in area ca1 or the dentate gyrus, and diffuse immunostaining of small cell bodies dispersed throughout the hippocampus but most numerous in the vicinity of the stratum pyramidale and in the alveus. |
1989-06-02 |
2023-08-11 |
rat |
| J W Swann, R J Brady, D L Marti. Postnatal development of GABA-mediated synaptic inhibition in rat hippocampus. Neuroscience. vol 28. issue 3. 1989-05-31. PMID:2710330. |
glutamate decarboxylase activities in microdissected ca3 and ca1 subfields were similar in immature hippocampus. |
1989-05-31 |
2023-08-11 |
rat |
| J W Swann, R J Brady, D L Marti. Postnatal development of GABA-mediated synaptic inhibition in rat hippocampus. Neuroscience. vol 28. issue 3. 1989-05-31. PMID:2710330. |
these results demonstrate dramatic differences in the ontogenesis of functional gabaergic inhibitory synaptic transmission in the ca1 and ca3 subfields of rat hippocampus. |
1989-05-31 |
2023-08-11 |
rat |
| J Bachevalier, M Mishki. Mnemonic and neuropathological effects of occluding the posterior cerebral artery in Macaca mulatta. Neuropsychologia. vol 27. issue 1. 1989-05-26. PMID:2710318. |
the only subfields of the hippocampus damaged in common in these cases were ca1 and ca2. |
1989-05-26 |
2023-08-11 |
monkey |
| K F Hauser, P J McLaughlin, I S Zago. Endogenous opioid systems and the regulation of dendritic growth and spine formation. The Journal of comparative neurology. vol 281. issue 1. 1989-05-11. PMID:2925898. |
pyramidal cells from the frontoparietal cortex (layer iii) and hippocampal field ca1, and cerebellar purkinje cells, were impregnated by using the golgi-kopsch method; total and mean dendrite segment length, branch frequency, and spine concentration were analyzed morphometrically. |
1989-05-11 |
2023-08-11 |
rat |
| H E Scharfman, D D Kunkel, P A Schwartzkroi. Intracellular dyes mask immunoreactivity of hippocampal interneurons. Neuroscience letters. vol 96. issue 1. 1989-05-11. PMID:2927710. |
the results of several studies have suggested that local circuit neurons, or interneurons, of area ca1 of hippocampus use gamma-aminobutyric acid (gaba) as their neurotransmitter. |
1989-05-11 |
2023-08-11 |
Not clear |
| W Kamphuis, E Huisman, W J Wadman, F H Lopes da Silv. Decrease in GABA immunoreactivity and alteration of GABA metabolism after kindling in the rat hippocampus. Experimental brain research. vol 74. issue 2. 1989-05-05. PMID:2924857. |
the long-term enhanced seizure sensitivity, characteristic for kindled animals, may be due to a decreased gabaergic inhibitory control of the neuronal circuitry in the ca1 region of the hippocampus. |
1989-05-05 |
2023-08-11 |
rat |
| L Aniksztejn, M P Roisin, R Amsellem, Y Ben-Ar. Long-term potentiation in the hippocampus of the anaesthetized rat is not associated with a sustained enhanced release of endogenous excitatory amino acids. Neuroscience. vol 28. issue 2. 1989-04-18. PMID:2564172. |
the relationship between long-term potentiation of synaptic transmission and the release of endogenous glutamate and aspartate has been investigated in the ca1 region of the hippocampus and in the fascia dentata of the anaesthetized rat. |
1989-04-18 |
2023-08-11 |
rat |
| H J Sheedlo, G J Siegel, S A Erns. Immunocytochemical localization of (Na+ + K+)-ATPase in the rat hippocampus. Neuroscience letters. vol 97. issue 1-2. 1989-04-06. PMID:2537478. |
in the ca1, ca2 and ca3 hippocampal regions, dense immunostaining for (na+ + k+)-atpase, exhibiting a punctate appearance, was demonstrated along the soma plasmalemma of hippocampal pyramidal cells in the stratum pyramidale, thus outlining these cells distinctly, and along dendrites extending into the stratum radiatum. |
1989-04-06 |
2023-08-11 |
rat |
| J Kapur, J L Stringer, E W Lothma. Evidence that repetitive seizures in the hippocampus cause a lasting reduction of GABAergic inhibition. Journal of neurophysiology. vol 61. issue 2. 1989-04-06. PMID:2918363. |
a method was developed to quantify paired-pulse depression of population spikes in the ca1 region of the hippocampus of urethane-anesthetized rats with paired stimuli to the contralateral ca3 region at various states of excitability of pyramidal cells. |
1989-04-06 |
2023-08-11 |
rat |
| J Kapur, E W Lothma. Loss of inhibition precedes delayed spontaneous seizures in the hippocampus after tetanic electrical stimulation. Journal of neurophysiology. vol 61. issue 2. 1989-04-06. PMID:2918364. |
paired-pulse depression in the ca1 region of the hippocampus was measured before administration of stimulus trains, in the quiescent period following the trains, and during and after spontaneous seizures. |
1989-04-06 |
2023-08-11 |
rat |
| R M Sapolsky, B A Stei. Status epilepticus-induced hippocampal damage is modulated by glucose availability. Neuroscience letters. vol 97. issue 1-2. 1989-04-06. PMID:2919000. |
kainic acid administration induces status epilepticus seizures in the rat which damage ca1 and ca3 hippocampal neurons. |
1989-04-06 |
2023-08-11 |
rat |