| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chen Yan, Valentina Mercaldo, Alexander D Jacob, Emily Kramer, Andrew Mocle, Adam I Ramsaran, Lina Tran, Asim J Rashid, Sungmo Park, Nathan Insel, A David Redish, Paul W Frankland, Sheena A Jossely. Higher-order interactions between hippocampal CA1 neurons are disrupted in amnestic mice. Nature neuroscience. 2024-07-19. PMID:39030342. |
here we tested whether contextual threat memory retrieval in mice relies on higher-order interactions between dorsal ca1 hippocampal neurons requiring learning-induced dendritic spine plasticity. |
2024-07-19 |
2024-07-22 |
mouse |
| Li Wei, Xiaopeng Yu, Hui Chen, Yupeng D. The role of P2X4R in regulating CA1 hippocampal synaptic impairment in LPS-induced depression. Journal of affective disorders. 2024-07-17. PMID:39019229. |
the role of p2x4r in regulating ca1 hippocampal synaptic impairment in lps-induced depression. |
2024-07-17 |
2024-07-20 |
Not clear |
| Rabia Anjum, Vernon R J Clarke, Yutaro Nagasawa, Hideji Murakoshi, Suzanne Paradi. Rem2 interacts with CaMKII at synapses and restricts long-term potentiation in hippocampus. PloS one. vol 19. issue 7. 2024-07-12. PMID:38995900. |
here, we report that knock out of rem2 enhances ltp at the schaffer collateral to ca1 synapse in hippocampus, consistent with an inhibitory action of rem2 on camkii in vivo. |
2024-07-12 |
2024-07-15 |
mouse |
| Sara N Bramlett, Shana M Fitzmaurice, Nicholas H Harbin, Wuji Yan, Charan Bandlamudi, G Emme Van Doorn, Yoland Smith, John R Heple. Regulator of G Protein Signaling 14 protein expression profile in the adult mouse brain. bioRxiv : the preprint server for biology. 2024-07-09. PMID:38979272. |
however, our more recent work with adult rhesus macaque brain shows that rgs14 is found in multiple neuron populations throughout hippocampal area ca1 and ca2, caudate nucleus, putamen, globus pallidus, substantia nigra, and amygdala in the adult rhesus monkey brain. |
2024-07-09 |
2024-07-12 |
mouse |
| Wenyan Zhao, Wei Zhang, Yingying Hu, Yuliang Zhou, Jinying Zhao, Yahong Li, Zhipeng X. AdipoRon Ameliorates Synaptic Dysfunction and Inhibits tau Hyperphosphorylation through the AdipoR/AMPK/mTOR Pathway in T2DM Mice. Neurochemical research. vol 49. issue 8. 2024-07-09. PMID:38819697. |
in addition, adiporon treatment up-regulated synaptic proteins (psd95, syn, gap43, and syp), increased the number of hippocampal synapses and attenuated synaptic damage, including the length, the number and the density of dendritic spines in ca1 and dg regions. |
2024-07-09 |
2024-07-12 |
mouse |
| M Angeles Luque, Sara Morcuende, Blas Torres, Luis Herrer. Kv7/M channel dysfunction produces hyperexcitability in hippocampal CA1 pyramidal cells of Fmr1 knockout mice. The Journal of physiology. 2024-07-08. PMID:38976504. |
here we show that pyramidal cells (pcs) in the dorsal ca1 region of the hippocampus elicited a larger action potential (ap) number in response to suprathreshold stimulation in juvenile fmr1 knockout (ko) than wild-type (wt) mice. |
2024-07-08 |
2024-07-12 |
mouse |
| Mona Rahdar, Shima Davoudi, Samaneh Dehghan, Mohammad Javan, Narges Hosseinmardi, Gila Behzadi, Mahyar Janahmad. Reversal of electrophysiological and behavioral deficits mediated by 5-HT7 receptor upregulation following LP-211 treatment in an autistic-like rat model induced by prenatal valproic acid exposure. Neuropharmacology. vol 257. 2024-07-05. PMID:38964596. |
recently, we have reported research has shown a significant decrease in serotonergic neurons originating from the raphe nuclei and projecting to the ca1 region of the dorsal hippocampus in autistic-like rats. |
2024-07-05 |
2024-07-08 |
rat |
| Mona Rahdar, Shima Davoudi, Samaneh Dehghan, Mohammad Javan, Narges Hosseinmardi, Gila Behzadi, Mahyar Janahmad. Reversal of electrophysiological and behavioral deficits mediated by 5-HT7 receptor upregulation following LP-211 treatment in an autistic-like rat model induced by prenatal valproic acid exposure. Neuropharmacology. vol 257. 2024-07-05. PMID:38964596. |
this study presents new evidence indicating an upregulation of 5-ht7r in the ca1 subregion of the hippocampus following the induction of autism. |
2024-07-05 |
2024-07-08 |
rat |
| Qinghe Li, Zhicui Ouyang, Yunqiao Zhang, Zhen Li, Xing Zhu, Zhen Tan. Effect of Early Inhibition of Toll-Like Receptor 4 on Hippocampal Plasticity in a Neonatal Rat Model of Hypoxic-Ischemic Brain Damage. Molecular neurobiology. 2024-07-02. PMID:38954251. |
finally,tak-242 increased the percentage of third-grade dendritic mushroom spines processes in the basal and apical segments of neurons in the hippocampal ca1 region at 21 days after hibd.therefore, we conclude that preinhibition of tlr4 prior to neonatal hibd improved the plasticity of the hippocampus. |
2024-07-02 |
2024-07-06 |
rat |
| Ana Paula Rodrigues Martini, Livia Machado Schlemmer, Joelma Alves Lucio Padilha, Rafael Bandeira Fabres, Natividade de Sá Couto Pereira, Lenir Orlandi Pereira, Carla Dalmaz, Carlos Alexandre Nett. Acrobatic training prevents learning impairments and astrocyte remodeling in the hippocampus of rats undergoing chronic cerebral hypoperfusion: sex-specific benefits. Frontiers in rehabilitation sciences. vol 5. 2024-06-28. PMID:38939055. |
we investigated the effects of acrobatic training on astrocyte remodeling in the ca1 and ca3 subfields of the hippocampus and spatial memory impairment in male and female rats at different stages of the two-vessel occlusion (2vo) model. |
2024-06-28 |
2024-06-30 |
rat |
| D K Avrova, L V Bayunova, N F Avrova, I O Zakharov. The Effect of Intranasal Administration of Gangliosides on the Viability of CA1 Hippocampal Neurons in Rat Two-Vessel Occlusion Model of Forebrain Ischemia/Reperfusion Injury. Bulletin of experimental biology and medicine. 2024-06-21. PMID:38907060. |
the expression of neurotrophic factor bdnf in the ca1 region of hippocampus did not differ in sham-operated rats and animals exposed to ischemia/reperfusion. |
2024-06-21 |
2024-06-24 |
rat |
| Ivette Espinoza, Francisco Cabrera, Julio César Morales-Medina, Ma de Jesús Gómez-Villalobos, Gonzalo Flore. The administration of Cerebrolysin elicits neuroprotective and neurorepair effects in an animal model of type 1 diabetes mellitus. Behavioural brain research. 2024-06-19. PMID:38897418. |
this research aims to investigate the neuroprotective and neurorepair effect of cbl on the cytoarchitecture of neurons and spine density in pyramidal neurons of the prefrontal (pfc) and the ca1 region of the dorsal hippocampus, as well as spheroidal neurons of the dentate gyrus (dg), in stz-induced dm. |
2024-06-19 |
2024-06-22 |
rat |
| Ivette Espinoza, Francisco Cabrera, Julio César Morales-Medina, Ma de Jesús Gómez-Villalobos, Gonzalo Flore. The administration of Cerebrolysin elicits neuroprotective and neurorepair effects in an animal model of type 1 diabetes mellitus. Behavioural brain research. 2024-06-19. PMID:38897418. |
in the first experimental condition, cbl treatment preserved the neuronal morphology in pfc layer 3, pfc layer 5 and the dg of the hippocampus, while also maintaining spine density in the pfc-3, dg and ca1 hippocampus. |
2024-06-19 |
2024-06-22 |
rat |
| Ivette Espinoza, Francisco Cabrera, Julio César Morales-Medina, Ma de Jesús Gómez-Villalobos, Gonzalo Flore. The administration of Cerebrolysin elicits neuroprotective and neurorepair effects in an animal model of type 1 diabetes mellitus. Behavioural brain research. 2024-06-19. PMID:38897418. |
furthermore, cbl induced neurorepair in neurons within the pfc-3, pfc-5 and ca1 regions of the hippocampus, along with an increase in spine density in the pfc-3, dg and ca1 hippocampus. |
2024-06-19 |
2024-06-22 |
rat |
| Jéssica Rabelo Bezerra, Tyciane de Souza Nascimento, Juliete Tavares, Mayara Sandrielly Soares de Aguiar, Maiara Virgínia Viana Maia, Geanne Matos de Andrad. Neuroprotective Effect of Chlorogenic Acid in an Animal Model of Sporadic Alzheimer's Disease Induced by Streptozotocin. Molecular neurobiology. 2024-06-19. PMID:38898198. |
additionally, it prevented bdnf depletion in the prefrontal cortex and hippocampus (ca1, ca3, and dg regions), and mitigated astrogliosis and microgliosis in the prefrontal cortex and hippocampus (ca1, ca3, and dg regions). |
2024-06-19 |
2024-06-22 |
mouse |
| Sri-Arun Iamjan, Siriluk Veerasakul, Gavin P Reynolds, Samur Thanoi, Sutisa Nudmamud-Thano. Regional-specific changes in rat brain BDNF in a model of methamphetamine abuse. Neuroscience letters. 2024-06-17. PMID:38885757. |
the results showed that hippocampal ca1 bdnf protein was significantly increased by 72 % above control values in the ed-binge rats, while other hippocampal regions and frontal cortex were not significantly affected. |
2024-06-17 |
2024-06-21 |
rat |
| Eric W Buss, Yu-Qiu Jiang, Bina Santoro, David H Brann, Daniel A Nicholson, Steven A Siegelbaum, Qian Su. Regulation by presynaptic NMDA receptors of non-linear postsynaptic summation of the cortical input to CA1 pyramidal neurons. Neuroscience. 2024-06-15. PMID:38878815. |
entorhinal cortex (ec) liii and lii glutamatergic neurons make monosynaptic connections onto distal apical dendrites of ca1 and ca2 pyramidal neurons (pns) in the hippocampus, respectively, through perforant path (pp) projections. |
2024-06-15 |
2024-06-18 |
mouse |
| Eric W Buss, Yu-Qiu Jiang, Bina Santoro, David H Brann, Daniel A Nicholson, Steven A Siegelbaum, Qian Su. Regulation by presynaptic NMDA receptors of non-linear postsynaptic summation of the cortical input to CA1 pyramidal neurons. Neuroscience. 2024-06-15. PMID:38878815. |
moreover, we found that the number of nmdars in pp terminals innervating ca1 pns is significantly greater than that found in pp terminals innervating ca2 pns, providing a potential explanation for the difference in temporal summation in these two classes of hippocampal pns. |
2024-06-15 |
2024-06-18 |
mouse |
| Walaa G Abdelhamid, Noha A Mowaad, Gihan F Asaad, Asmaa F Galal, Sarah S Mohammed, Olfat E Mostafa, Doaa R Sadek, Lobna A Elkhate. The potential protective effect of Camellia Sinensis in mitigating monosodium glutamate-induced neurotoxicity: biochemical and histological study in male albino rats. Metabolic brain disease. 2024-06-13. PMID:38869783. |
msg administration resulted in significant neurotoxicity in rats that was revealed by the significant reduction of serum concentration of glutathione peroxidase (gpx) and nitric oxide (no), and the significant elevation of total antioxidant capacity (tac) accompanied by the significant reduction of levels of serum monoamines (dopamine, serotonin, and norepinephrine) and histological changes in the hippocampus area ca1, dentate gyrus, and cerebellar cortex and positive immunohistochemical staining of glial fibrillary acidic proteins (gfap) and calretinin. |
2024-06-13 |
2024-06-15 |
rat |
| Myung Chung, Katsutoshi Imanaka, Ziyan Huang, Akiyuki Watarai, Mu-Yun Wang, Kentaro Tao, Hirotaka Ejima, Tomomi Aida, Guoping Feng, Teruhiro Okuyam. Conditional knockout of Shank3 in the ventral CA1 by quantitative in vivo genome-editing impairs social memory in mice. Nature communications. vol 15. issue 1. 2024-06-12. PMID:38866749. |
a series of our previous studies revealed that hippocampal ventral ca1 (vca1) neurons possess social memory engram and that the neurophysiological representation of social memory in the vca1 neurons is disrupted in asd-associated shank3 knockout mice. |
2024-06-12 |
2024-06-15 |
mouse |