| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Seyda Koc, Ekin Erdogmus, Ozlem Bozdemir, Deniz Ozkan-Vardar, Unzile Yaman, Pınar Erkekoglu, Naciye Dilara Zeybek, Belma Kocer-Gumuse. Prepubertal phthalate exposure can cause histopathological alterations, DNA methylation and histone acetylation changes in rat brain. Toxicology and industrial health. 2025-01-28. PMID:39873534. |
examining the hippocampus under the light microscope, pyramidal neuron loss was detected only in ca1 of the dehp-l group, while in dehp-h rats, pyramidal neuron losses were detected in the ca1, ca2, and ca3 regions. |
2025-01-28 |
2025-01-30 |
rat |
| Earl T Gilbert, Lianne M F Klaver, Kaiser C Arndt, Jongwoon Kim, Xiaoting Jia, Sam McKenzie, Daniel Fine Englis. Reciprocal interactions between CA1 pyramidal and axo-axonic cells control sharp wave-ripple events. bioRxiv : the preprint server for biology. 2025-01-27. PMID:39868302. |
for example, in hippocampus area ca1 the competition between inhibition and excitation organizes spike timing of pyramidal cells (pyr) in network events, including sharp wave-ripples (spw-r). |
2025-01-27 |
2025-01-29 |
mouse |
| Abdelaziz M Hussein, Ahmed F Abouelnaga, Walaa Obydah, Somaya Saad, Marwa Abass, Asmaa Yehia, Eman M Ibrahim, Ahmed T Ahmed, Osama A Abulseou. Lateral hypothalamic area high-frequency deep brain stimulation rescues memory decline in aged rat: behavioral, molecular, and electrophysiological study. Pflugers Archiv : European journal of physiology. 2025-01-21. PMID:39836224. |
old rats show significant decline in memories, antioxidant genes (nrf2 and ho-1), antioxidants (gsh and catalase), hsp70, bdnf, and synaptophysin with significant increase in mda in hippocampus (p < 0.05) and dbs for lha caused a significant improvement in memories in old rats, with significant rise in fast gamma and theta waves in ca1 region in old rats (p < 0.05). |
2025-01-21 |
2025-01-23 |
rat |
| Abdelaziz M Hussein, Ahmed F Abouelnaga, Walaa Obydah, Somaya Saad, Marwa Abass, Asmaa Yehia, Eman M Ibrahim, Ahmed T Ahmed, Osama A Abulseou. Lateral hypothalamic area high-frequency deep brain stimulation rescues memory decline in aged rat: behavioral, molecular, and electrophysiological study. Pflugers Archiv : European journal of physiology. 2025-01-21. PMID:39836224. |
this might be due to increase in fast gamma in ca1, attenuation of oxidative stress, upregulation of nrf2, ho-1, hsp70, bdnf, and synaptophysin in the hippocampus. |
2025-01-21 |
2025-01-23 |
rat |
| Charlie Lovatt, Thomas J O'Sullivan, Clara Ortega-de San Luis, Tomas J Ryan, Rene A W Fran. Memory engram synapse 3D molecular architecture visualized by cryoCLEM-guided cryoET. bioRxiv : the preprint server for biology. 2025-01-20. PMID:39829918. |
here, we demonstrate the use of engram labelling technology and cryogenic correlated light and electron microscopy (cryoclem)-guided cryogenic electron tomography (cryoet) to visualize the in-tissue 3d molecular architecture of engram synapses of a contextual fear memory within the ca1 region of the mouse hippocampus. |
2025-01-20 |
2025-01-23 |
mouse |
| Ivette Espinoza, Ma de Jesús Gómez-Villalobos, Leonardo Aguilar-Hernández, Gonzalo Flores, Julio César Morales-Medin. Cerebrolysin treatment improved short-term memory deficits while simultaneously increasing hippocampal spine density in hypertensive female rats. Behavioural brain research. vol 481. 2025-01-19. PMID:39826813. |
this research aims to investigate the behavioral outcomes in locomotion and recognition memory in the novel object recognition test (nort) and assess the neuroreparative effect of cbl on the cytoarchitecture of neurons and the spine density in pyramidal neurons of the prefrontal cortex (pfc), the entorhinal cortex (ec) and the ca1 region of the dorsal hippocampus, as well as spheroidal neurons of the dentate gyrus (dg). |
2025-01-19 |
2025-01-23 |
rat |
| Ivette Espinoza, Ma de Jesús Gómez-Villalobos, Leonardo Aguilar-Hernández, Gonzalo Flores, Julio César Morales-Medin. Cerebrolysin treatment improved short-term memory deficits while simultaneously increasing hippocampal spine density in hypertensive female rats. Behavioural brain research. vol 481. 2025-01-19. PMID:39826813. |
moreover, cbl treatment increased arborization in both normotensive and hypertensive rats in the ca1, and dg regions of hippocampus and ec and selectively increased spine density in the hippocampus of hypertensive rats. |
2025-01-19 |
2025-01-23 |
rat |
| Made Astawan, Aprilia F Damayanti, Tutik Wresdiyati, Diana N Afifah, Irma S Rahmawat. Potential of soybean-velvet bean combination tempe in improving cognitive function. Narra J. vol 4. issue 3. 2025-01-16. PMID:39816105. |
this study examined cognitive performance by measuring maze completion time, while brain mass and volume, hippocampus histology for neuron cell counts in the dentate gyrus section, cornu ammonis 1 (ca1), and cornu ammonis 3 (ca3), brain dopamine and β- amyloid serum levels were measured after eight weeks of intervention. |
2025-01-16 |
2025-01-19 |
rat |
| Anqing Liu, Qingqiang Tu, Ming Huan. Feasibility study of PET/CT for the detection and localization of nervous system damage caused by trimethyltin chloride. Scientific reports. vol 15. issue 1. 2025-01-09. PMID:39779731. |
moreover, tmt induced neuronal damage within the cerebral cortex, hippocampal ca1, ca3 and dg regions as well as the cerebellum while also promoting gliosis surrounding the hippocampus. |
2025-01-09 |
2025-01-13 |
rat |
| Ingrid Dudink, Amy E Sutherland, Margie Castillo-Melendez, Elham Ahmadzadeh, Tegan A White, Atul Malhotra, Harold A Coleman, Helena C Parkington, Justin M Dean, Yen Pham, Tamara Yawno, Tara Sepehrizadeh, Graham Jenkin, Emily J Camm, Beth J Allison, Suzanne L Mille. Fetal growth restriction adversely impacts trajectory of hippocampal neurodevelopment and function. Brain pathology (Zurich, Switzerland). 2025-01-09. PMID:39780443. |
ex vivo electrophysiology analysis shows that paired-pulse facilitation was reduced in fgr compared to controls for cornu ammonis 1 hippocampal outputs, reflecting synaptic dysfunction. |
2025-01-09 |
2025-01-13 |
Not clear |
| Melis Onay, Patrick N Harter, Katherina Weber, Albrecht Piiper, Marcus Czabanka, Karl H Plate, Thomas M Freiman, Florian Gessler, Barbara Puhahn-Schmeise. Mossy Fiber Sprouting in Temporal Lobe Epilepsy: The Impact of Netrin-1, DCC, and Gene Expression Changes. Biomedicines. vol 12. issue 12. 2025-01-08. PMID:39767775. |
temporal lobe epilepsy (tle) is the most common form of drug-resistant epilepsy, often associated with hippocampal sclerosis (hs), which involves selective neuronal loss in the cornu ammonis subregion 1 ca1 and ca4 regions of the hippocampus. |
2025-01-08 |
2025-01-13 |
Not clear |
| Muhammad Zulfadhli Othman, Mohd Hamzah Mohd Nasir, Wan Amir Nizam Wan Ahmad, Jafri Malin Abdullah, Ahmad Tarmizi Che Ha. Differential regulation of KCC2 and NKCC1 expression by zolpidem in CA1 and CA3 hippocampal subregions of the lithium-pilocarpine status epilepticus rat model. Experimental animals. 2025-01-08. PMID:39779249. |
differential regulation of kcc2 and nkcc1 expression by zolpidem in ca1 and ca3 hippocampal subregions of the lithium-pilocarpine status epilepticus rat model. |
2025-01-08 |
2025-01-13 |
rat |
| Zeinab Hamidizad, Mehri Kadkhodaee, Farzaneh Kianian, Mina Ranjbaran, Fatemeh Heidari, Behjat Seif. Neuroprotective Effects of Sodium Nitroprusside on CKD-Induced Cognitive Dysfunction in Rats: Role of CBS and Nrf2/HO-1 Pathway. Neuromolecular medicine. vol 27. issue 1. 2025-01-08. PMID:39775152. |
as predicted, the levels of bun and scr (both p < 0.001) and neuronal injury in the hippocampus (p < 0.001 for ca1; ca3; dg) and prefrontal cortex (p < 0.001) increased in ckd rats as well as 5/6nx induced reduction of nrf2 (both p < 0.001) /ho-1(p < 0.001; p < 0.01 respectively) pathway activity in the hippocampus and prefrontal cortex in ckd rats. |
2025-01-08 |
2025-01-13 |
rat |
| Zeinab Hamidizad, Mehri Kadkhodaee, Farzaneh Kianian, Mina Ranjbaran, Fatemeh Heidari, Behjat Seif. Neuroprotective Effects of Sodium Nitroprusside on CKD-Induced Cognitive Dysfunction in Rats: Role of CBS and Nrf2/HO-1 Pathway. Neuromolecular medicine. vol 27. issue 1. 2025-01-08. PMID:39775152. |
snp treatment significantly improved nrf2 (both p < 0.001) /ho-1 (p < 0.001; p < 0.05 respectively) pathways and neuronal injury (p < 0.001 for ca1; ca3; dg) in the hippocampus and prefrontal cortex in ckd rats as well as enhanced learning and memory ability in ckd rats. |
2025-01-08 |
2025-01-13 |
rat |
| L Daniel Estrella, Andrew J Trease, Lexi Sheldon, Nashanthea J Roland, Howard S Fox, Kelly L Stauc. Tau association with synaptic mitochondria coincides with energetic dysfunction and excitatory synapse loss in the P301S tauopathy mouse model. Neurobiology of aging. vol 147. 2025-01-08. PMID:39778459. |
for this reason, using 3-month-old wild-type and human mutant tau p301s transgenic mice, we investigated the association of tau with mitochondria, synaptosome bioenergetics, and characterized excitatory synaptic loss across hippocampal regions (dentate gyrus, perisomatic ca3, and perisomatic ca1) and in the parietal cortex. |
2025-01-08 |
2025-01-13 |
mouse |
| George Trompoukis, Athina Miliou, Costas Papatheodoropoulo. β-adrenergic receptor-induced E-S potentiation in the dorsal and ventral hippocampus. Frontiers in synaptic neuroscience. vol 16. 2025-01-06. PMID:39758826. |
to explore potential dorsoventral differences in β-ar-mediated effects, we applied the β-ar agonist isoproterenol (10 μm, 30 min) to dorsal and ventral hippocampal slices, recording field excitatory postsynaptic potentials (fepsps) and population spikes (pss) from the ca1 region. |
2025-01-06 |
2025-01-08 |
Not clear |
| Yujie Wu, Wolfgang Maas. A simple model for Behavioral Time Scale Synaptic Plasticity (BTSP) provides content addressable memory with binary synapses and one-shot learning. Nature communications. vol 16. issue 1. 2025-01-03. PMID:39747916. |
altogether, our results create a link between synaptic plasticity in area ca1 of the hippocampus and its network function. |
2025-01-03 |
2025-01-05 |
Not clear |
| Sonia Irais Gonzalez-Cano, Ulises Peña-Rosas, Guadalupe Muñoz-Arenas, Diana Milena Torres-Cinfuentes, Samuel Treviño, Carolina Moran-Raya, Gonzalo Flores, Jorge Guevara, Alfonso Dia. Neuroprotective Effect of Curcumin-Metavanadate in the Hippocampus of Aged Rats. Synapse (New York, N.Y.). vol 79. issue 1. 2025-01-03. PMID:39748146. |
this work aimed to evaluate the coupling of metavanadate and curcumin (cuma-mv) on learning, memory, redox balance, neuroinflammation, and cell death in the hippocampal region (ca1 and ca3) and dentate gyrus (dg) of aged rats. |
2025-01-03 |
2025-01-05 |
rat |
| Merci N Best, Jonathan Levy, Amber Spencer, Lia Min, Einar Olafasson, Emile Pinarbasi, Jonny Sexton, Paul M Jenkins, Vernon B Carruthers, Henry L Paulso. Basic Science and Pathogenesis. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 20 Suppl 1. 2025-01-03. PMID:39750902. |
to better define the extent and variability of tau pathology in subregions of the hippocampus (dentate gyrus, ca4, ca3, ca2, ca1, subiculum, and parahippocampal gyrus), we examined psp brains available through the michigan brain bank. |
2025-01-03 |
2025-01-05 |
Not clear |
| Carly Norris, Susan F Murphy, Pamela J VandeVor. Acute astrocytic and neuronal regulation of glutamatergic protein expression following blast. Neuroscience letters. 2024-12-29. PMID:39734031. |
investigation of substructural and subregional effects in future studies, particularly within the hippocampus (e.g., dentate gyrus, ca1, ca2, ca3), may reveal localized changes in expression and/or nmdar subunit composition capable of potentiating btbi molecular cascades. |
2024-12-29 |
2025-01-01 |
rat |