| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marilou Poitras, Alexandra Doiron, Hélène Plamondo. Selective Estrogen Receptor Activation Prior to Global Cerebral Ischemia in Female Rats Impacts Microglial Activation and Anxiety-Like Behaviors Without Effects on CA1 Neuronal Injury. Behavioural brain research. 2024-06-06. PMID:38844057. |
microglial activation (iba1, cd68, cd86) in the basolateral amygdala (bla), ca1 of the hippocampus, and paraventricular nucleus of the hypothalamus (pvn) was determined 8 days post-ischemia. |
2024-06-06 |
2024-06-10 |
rat |
| Ye Li, Chen Xiao, Tian Lan, Wenjing Wang, Changmin Wang, Mengni Chang, Zhaoying Yu, Shuyan Y. Targeting Phactr4 to rescue chronic stress-induced depression-like behavior in rats via regulating neuroinflammation and neuroplasticity. International journal of biological macromolecules. 2024-06-05. PMID:38838879. |
in this study, proteomics analysis showed that the expression level of phosphatase and actin regulator 4 (phactr4) was significantly increased in the ca1 hippocampus of depressed rats. |
2024-06-05 |
2024-06-08 |
rat |
| Rong Ye, Anna E Goodheart, Joseph J Locascio, Erin Peterec, Michael Properzi, Emma G Thibault, Erin Chuba, Keith A Johnson, Michael J Brickhouse, Alexandra Touroutoglou, John H Growdon, Bradford C Dickerson, Stephen N Gompert. Differential Vulnerability of Hippocampal Subfields to Amyloid and Tau Deposition in the Lewy Body Diseases. Neurology. vol 102. issue 12. 2024-05-30. PMID:38815233. |
alzheimer disease (ad) copathologies of β-amyloid and tau are common in the lewy body diseases (lbd), dementia with lewy bodies (dlb) and parkinson disease (pd), and target distinct hippocampal subfields compared with lewy pathology, including subiculum and ca1. |
2024-05-30 |
2024-07-16 |
Not clear |
| Diana Chan, Kathryn D Baker, Rick Richardso. The impact of chronic fluoxetine treatment in adolescence or adulthood on context fear memory and perineuronal nets. Developmental psychobiology. vol 66. issue 5. 2024-05-29. PMID:38807259. |
here, we investigated the effect of fluoxetine exposure during adolescence or adulthood on context fear memory and pnns in the basolateral amygdala (bla), the ca1 subregion of the hippocampus, and the medial prefrontal cortex in rats. |
2024-05-29 |
2024-06-03 |
rat |
| Ren-Qi Li, Qiu-Ting Zeng, Mu-Huo Ji, Yue Zhang, Ming-Jie Mao, Shan-Wu Feng, Man-Lin Duan, Zhi-Qiang Zho. Oxytocin ameliorates cognitive impairments by attenuating excitation/inhibition imbalance of neurotransmitters acting on parvalbumin interneurons in a mouse model of sepsis-associated encephalopathy. Journal of biomedical research. 2024-05-29. PMID:38808550. |
golgi staining revealed hippocampal synaptic deterioration, local field potential recordings showed weakened gamma oscillations, and immunofluorescence analysis demonstrated decreased pv expression in the cornu ammonis 1 (ca1) region of the hippocampus following lps treatment, which was alleviated by oxytocin. |
2024-05-29 |
2024-06-03 |
mouse |
| Donald J Joseph, Markus Von Deimling, Rashmi Risbud, Almedia J McCoy, Eric D Mars. Loss of postnatal Arx transcriptional activity in parvalbumin interneurons reveals non-cell autonomous disturbances in CA1 pyramidal cells. Neuroscience. 2024-05-24. PMID:38788829. |
we recently demonstrated that postnatal ablation of the aristaless (arx) homeobox gene in parvalbumin interneurons (pvis) alone led to dysregulation of their transcriptome and alterations in their functional as well as network properties in the hippocampal cornu ammoni first region (ca1). |
2024-05-24 |
2024-05-27 |
mouse |
| Fares J P Sayegh, Lionel Mouledous, Catherine Macri, Juliana Pi Macedo, Camille Lejards, Claire Rampon, Laure Verret, Lionel Daha. Ventral tegmental area dopamine projections to the hippocampus trigger long-term potentiation and contextual learning. Nature communications. vol 15. issue 1. 2024-05-21. PMID:38773091. |
here, we used optogenetic manipulation of midbrain dopamine neurons in male dat::cre mice, and discovered that stimulating the schaffer collaterals - the glutamatergic axons connecting ca3 and ca1 regions - of the dorsal hippocampus concomitantly with midbrain dopamine terminals within a 200 millisecond time-window triggers ltp at glutamatergic synapses. |
2024-05-21 |
2024-05-27 |
mouse |
| Kang-In Lee, Min-Soo Kim, Heung Joo Yuk, Yousang Jo, Hye Jin Kim, Jieun Kim, Hyungjun Kim, Ju-Young Shin, Donghwan Kim, Ki-Sun Par. Alleviating depressive-like behavior in DSS-induced colitis mice: Exploring naringin and poncirin from Poncirus trifoliata extracts. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 175. 2024-05-21. PMID:38772154. |
in the cornu ammonis 1 (ca1) and dentate gyrus (dg) regions of the hippocampus, pt controlled the neuroinflammatory responses of proliferated microglia. |
2024-05-21 |
2024-05-27 |
mouse |
| Linda Bean, Prodip K Bose, Asha Rani, Ashok Kuma. Serine racemase expression profile in the prefrontal cortex and hippocampal subregions during aging in male and female rats. Aging. vol 16. 2024-05-18. PMID:38761177. |
however, age-associated changes in sr expression levels in the medial and lateral prefrontal cortex (mpfc, lpfc), and in the dorsal hippocampal subfields, ca1, ca3, and dentate gyrus (dg), have not been thoroughly elucidated. |
2024-05-18 |
2024-05-27 |
rat |
| Nestor I Martínez-Torres, Jhonathan Cárdenas-Bedoya, Blanca Miriam Torres-Mendoz. Acute combined cerebrolysin and nicotinamide administration promote cognitive recovery through neuronal changes in the hippocampus of rats with permanent middle cerebral artery occlusion. Neuroscience. 2024-05-11. PMID:38734304. |
the rats were evaluated in the novel object recognition test; hippocampal infarct area measurement; reconstruction of neurons from ca1 for sholl analysis; and, measurement of brain-derived neurotrophic factor (bdnf) levels near the infarct zone. |
2024-05-11 |
2024-05-27 |
rat |
| Apoorva Bettagere Shivakumar, Sonam Fathima Mehak, Feyba Jijimon, Gireesh Gangadhara. Extra-hippocampal contributions to social memory: The role of septal nuclei. Biological psychiatry. 2024-05-08. PMID:38718881. |
the hippocampus, especially the circuit linking dorsal ca2 and ventral ca1 neurons, is considered a neural substrate for social memory formation. |
2024-05-08 |
2024-05-27 |
Not clear |
| Zhengdong Yang, You Wu, Jun Tang, Renhuai Liu, Zongping Fang, Binxiao S. [Cannabinoid receptor 1 agonist arachidonyl-2'-chloroethylamide (ACEA) improves sepsis-associated encephalopathy by inhibiting inflammatory factors]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 40. issue 4. 2024-05-06. PMID:38710516. |
compared to the control group, the lps group showed significant increases in mrna of inflammatory factors such as il-6, tnf-α, and il-1β, together with significant increases in il-6 and tnf-α protein levels in the hippocampus, a decrease in nissl bodies in the ca1 region, and significant cognitive dysfunction. |
2024-05-06 |
2024-05-27 |
mouse |
| Xiayu Gong, Zhixin Fan, Hanfang Xu, Yue Qu, Bozhi Li, Lanxin Li, Yuqi Yan, Lili Wu, Can Ya. GABAergic interneurons in the hippocampal CA1 mediate contextual fear generalization in PTSD rats. Journal of neurochemistry. 2024-05-05. PMID:38705582. |
in the present study, we established a rat model of ptsd with inescapable foot shocks (ifs) and observed the loss of gabaergic interneuron phenotype in the hippocampal cornu ammonis-1 (ca1) subfield. |
2024-05-05 |
2024-05-08 |
rat |
| Valeria Cogut, Maaike Goris, Aukje Jansma, Marrit van der Staaij, Robert H Hennin. Hippocampal neuroimmune response in mice undergoing serial daily torpor induced by calorie restriction. Frontiers in neuroanatomy. vol 18. 2024-05-01. PMID:38686173. |
concurrently, the ca1 region of the hippocampus showed persistent morphological changes in microglia, characterized by reduced cell branching, decreased cell complexity and altered shape. |
2024-05-01 |
2024-05-03 |
mouse |
| Dan Huang, Yunhui Fan, Jingjun Zhang, Qianfeng Wang, Ming Ding, Ruiqing Hou, Kewei Yu, Xiao Xiao, Yi Wu, Junfa W. Dorsal dentate gyrus mediated enriched environment-induced anxiolytic and antidepressant effects in cortical infarcted mice. Experimental neurology. 2024-04-30. PMID:38685308. |
compared to the mice housing in a standard environment, those subjected to acute ee stimulation had significantly increased alff and reho values in the bilateral somatosensory cortex (s1, s2), dorsal dentate gyrus (ddg), dorsal ca1 of hippocampus (dca1), lateral habenular nucleus (lhb), periaqueductal gray (pag), ipsilateral primary motor cortex (m1), retrosplenial cortex (rsc), parietal association cortex (pta), dorsal ca3 of hippocampus (dca3), claustrum (cl), ventral pallidum (vp), amygdala (amy), and contralateral auditory cortex (au). |
2024-04-30 |
2024-05-03 |
mouse |
| Guadalupe Herrera, Teresa Scimonelli, Lasaga Mercedes, Gladys Granero, Renée Onnaint. Polysorbate 80 coated chitosan nanoparticles for delivery of α-Melanocyte Stimulating Hormone analog (NDP-MSH) to the brain reverse cognitive impairment related to neuroinflammation produced by a high-fat diet (HFD). Neuropharmacology. 2024-04-30. PMID:38688422. |
intraperitoneal injection of fitc-ps80/cs nps and [ndp-msh]-ps80/cs np in rats demonstrated their ability to cross the blood-brain barrier, reach the brain, and accumulate in ca1 neurons of the dorsal hippocampus within 2 hours. |
2024-04-30 |
2024-05-03 |
rat |
| Dae Won Kim, Tae-Kyeong Lee, Ji Hyeon Ahn, Se-Ran Yang, Myoung Cheol Shin, Jun Hwi Cho, Moo-Ho Won, Il Jun Kang, Joon Ha Par. Porphyran Attenuates Neuronal Loss in the Hippocampal CA1 Subregion Induced by Ischemia and Reperfusion in Gerbils by Inhibiting NLRP3 Inflammasome-Mediated Neuroinflammation. Marine drugs. vol 22. issue 4. 2024-04-26. PMID:38667787. |
the aim of this study was to examine the neuroprotective effects of porphyran against brain ir injury and its underlying mechanisms using a gerbil model of transient forebrain ischemia (ir in the forebrain), which results in pyramidal cell (principal neuron) loss in the cornu ammonis 1 (ca1) subregion of the hippocampus on day 4 after ir. |
2024-04-26 |
2024-04-28 |
Not clear |
| Zhu Wang, Bowen Li, Jingrui Yang, Ying Gao, Liu Gao, Qiang Jia, Li Yu, Yunzhi Lin. ML365 ameliorates postoperative cognitive impairment in aged mice by inhibiting NLRP3 inflammasome activation in the hippocampus. Brain research. 2024-04-25. PMID:38663469. |
ml365 pretreatment also reduced nlrp3, caspase-1, asc and il-1β expression levels in the hippocampus, improved pocd-induced pathological changes in the hippocampal ca1 and ca3 areas of aged mice, and decreased levels of plasma mda and oxidative stress. |
2024-04-25 |
2024-04-28 |
mouse |
| Nicholas R Livingston, Amanda Kiemes, Gabriel A Devenyi, Samuel Knight, Paulina B Lukow, Luke A Jelen, Thomas Reilly, Aikaterini Dima, Maria Antonietta Nettis, Cecilia Casetta, Tyler Agyekum, Fernando Zelaya, Thomas Spencer, Andrea De Micheli, Paolo Fusar-Poli, Anthony A Grace, Steve C R Williams, Philip McGuire, Alice Egerton, M Mallar Chakravarty, Gemma Modino. Effects of diazepam on hippocampal blood flow in people at clinical high risk for psychosis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-04-24. PMID:38658738. |
regional cerebral blood flow (rcbf) was measured using 3d pseudo-continuous arterial spin labeling and sampled in native space using participant-specific hippocampus and subfield masks (ca1, subiculum, ca4/dentate gyrus). |
2024-04-24 |
2024-04-28 |
Not clear |
| Doris C Jackson, Richard M Burgon, Spencer Thompson, Sterling N Sudweek. Single-cell quantitative expression of nicotinic acetylcholine receptor mRNA in rat hippocampal interneurons. PloS one. vol 19. issue 4. 2024-04-18. PMID:38635806. |
using single-cell quantitative pcr to analyze rat ca1 hippocampal interneurons, we quantified neuronal nicotinic acetylcholine receptor (nachr) mrna subunit expression and detailed possible nachr subtype combinations for the α2, α3, α4, α5, α7, β2, β3, and β4 subunits. |
2024-04-18 |
2024-04-21 |
rat |