Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
M Lerner-Natoli, G Rondouin, M Belaidi, M Baldy-Moulinier, J M Kamenk. N-[1-(2-thienyl)cyclohexyl]-piperidine (TCP) does not block kainic acid-induced status epilepticus but reduces secondary hippocampal damage. Neuroscience letters. vol 122. issue 2. 1991-06-07. PMID:2027518. |
distant damage, localized in the ca3 and ca1 areas, was observed in the hippocampus of rats as a consequence of status epilepticus (se) induced by the injection of 2.5 nmol of kainic acid (ka) into the amygdala. |
1991-06-07 |
2023-08-11 |
rat |
S Krantic, J C Martel, D Weissmann, J F Pujol, R Quirio. Quantitative radioautographic study of somatostatin receptors heterogeneity in the rat extrahypothalamic brain. Neuroscience. vol 39. issue 1. 1991-05-24. PMID:1982463. |
for example, both superficial and deep cortical laminae, as well as the basolateral amygdaloid nucleus and ca1 hippocampal area exhibited different binding densities with [125i]tyr0-d-trp8-somatostatin14 depending on the competitor used in the assay (somatostatin14 or sms 201-995). |
1991-05-24 |
2023-08-11 |
rat |
W Stummer, K Weber, L Schürer, A Baethmann, O Kempsk. Electrical impedance, rCBF, survival and histology in Mongolian gerbils with forebrain ischaemia. Acta neurochirurgica. Supplementum. vol 51. 1991-05-24. PMID:2089890. |
neuronal loss was found in all animals in the hippocampus (ca1, ca2, ca3 and ca4), and was most pronounced in the ca1 sector. |
1991-05-24 |
2023-08-11 |
Not clear |
M J Somerville, M E Percy, C Bergeron, L K Yoong, E A Grima, D R McLachla. Localization and quantitation of 68 kDa neurofilament and superoxide dismutase-1 mRNA in Alzheimer brains. Brain research. Molecular brain research. vol 9. issue 1-2. 1991-05-21. PMID:1850065. |
the cerebellar cortex and hippocampal ca1 and ca2 regions were compared in these two groups of subjects, since in ad the ca2 region of the hippocampus and the cerebellum have been found to be relatively unaffected by the alzheimer process in comparison to the hippocampal ca1 region. |
1991-05-21 |
2023-08-11 |
human |
M J Somerville, M E Percy, C Bergeron, L K Yoong, E A Grima, D R McLachla. Localization and quantitation of 68 kDa neurofilament and superoxide dismutase-1 mRNA in Alzheimer brains. Brain research. Molecular brain research. vol 9. issue 1-2. 1991-05-21. PMID:1850065. |
the amount of nf68 mrna was reduced by approximately 50% in pyramidal cells of both the ca1 and ca2 of ad hippocampus (p less than 0.001), and by 15% in the purkinje cells of ad cerebellum (p less than 0.05) relative to that of the hd individuals. |
1991-05-21 |
2023-08-11 |
human |
A J Gibb, D Colquhou. Glutamate activation of a single NMDA receptor-channel produces a cluster of channel openings. Proceedings. Biological sciences. vol 243. issue 1306. 1991-05-20. PMID:1708142. |
activations of the n-methyl-d-aspartate (nmda) receptor by glutamate were studied in outside-out patches from ca1 cells in rat hippocampal slices. |
1991-05-20 |
2023-08-11 |
rat |
V K Gribkoff, L A Bauman, C P VanderMaele. A 1-heteroaryl-4-piperidinyl-methyl pyrrolidinone, BMY 21502, delays the decay of hippocampal synaptic potentiation in vitro. Neuropharmacology. vol 29. issue 11. 1991-05-20. PMID:2087253. |
the effects of the substituted pyrrolidinone, bmy 21502, on the properties of cell membranes, synaptic transmission and synaptic plasticity, were assessed in area ca1 of hippocampal slices from the rat. |
1991-05-20 |
2023-08-11 |
rat |
D Martin, G A Bustos, M A Bowe, S D Bray, J V Nadle. Autoreceptor regulation of glutamate and aspartate release from slices of the hippocampal CA1 area. Journal of neurochemistry. vol 56. issue 5. 1991-05-16. PMID:1672884. |
slices of hippocampal area ca1 were employed to test the hypothesis that the release of glutamate and aspartate is regulated by the activation of excitatory amino acid autoreceptors. |
1991-05-16 |
2023-08-11 |
Not clear |
M F Gonzalez, D Lowenstein, S Fernyak, K Hisanaga, R Simon, F R Shar. Induction of heat shock protein 72-like immunoreactivity in the hippocampal formation following transient global ischemia. Brain research bulletin. vol 26. issue 2. 1991-05-16. PMID:2012984. |
it is proposed that (a) the induction of hsp72 in hippocampal sectors correlates with their vulnerability to global ischemia (ca1 greater than hilus greater than ca3 greater than dentate gyrus); (b) the induction of hsp72 in hippocampal cells correlates with their vulnerability to global ischemia in that mild ischemia induced hsp72 only in neurons, moderate ischemia in neurons and glia, and severe ischemia only in capillary endothelial cells; (c) the failure to induce hsp72 in hippocampal neurons in 2 cases of 10 min ischemia may be related to severe injury causing disruption of protein synthesis in these cells. |
1991-05-16 |
2023-08-11 |
rat |
C Mourre, M L Smith, B K Siesjö, M Lazdunsk. Brain ischemia alters the density of binding sites for glibenclamide, a specific blocker of ATP-sensitive K+ channels. Brain research. vol 526. issue 1. 1991-04-26. PMID:2127731. |
in at least one of these, the ca1 sector of the hippocampus, cell death is preceded by neuronal hyperactivity, presumed to be caused by loss of inhibitory control. |
1991-04-26 |
2023-08-11 |
human |
H Whea. NMDA-receptors are involved in synaptic plasticity following partial denervation of CA1 hippocampal cells. Advances in experimental medicine and biology. vol 268. 1991-04-15. PMID:1963750. |
nmda-receptors are involved in synaptic plasticity following partial denervation of ca1 hippocampal cells. |
1991-04-15 |
2023-08-11 |
Not clear |
T O Reuhl, M Amador, J A Dan. Tissue culture tube contaminant inhibits excitatory synaptic channels. Brain research bulletin. vol 25. issue 3. 1991-04-11. PMID:1705471. |
the n-methyl-d-aspartate (nmda) subset of glutamate receptors was studied in ca1 hippocampal neurons. |
1991-04-11 |
2023-08-11 |
xenopus_laevis |
J A Shaw, V H Perry, J Mellanb. Tetanus toxin-induced seizures cause microglial activation in rat hippocampus. Neuroscience letters. vol 120. issue 1. 1991-04-09. PMID:2293095. |
after 7-14 days, many activated microglia are visible in ca1 area of dorsal hippocampus aligned with the pyramidal cell dendrites and having the morphology characteristic of 'rod cells'. |
1991-04-09 |
2023-08-11 |
mouse |
J J Hagan, M Beaughar. The effects of forebrain ischaemia on spatial learning. Behavioural brain research. vol 41. issue 2. 1991-04-04. PMID:2288667. |
the behavioural deficits were associated with neuropathological damage in the ca1 cell layer of the dorsal hippocampus with varying degrees of damage in layers ca2, ca3 and ca4. |
1991-04-04 |
2023-08-11 |
rat |
T Dalkara, E Tan, G Erdemli, R Onur, T Zilel. Electrophysiological evidence for activation of NMDA receptors and its antagonism by MK-801 in cerebral ischemia. Brain research. vol 532. issue 1-2. 1991-03-21. PMID:1980849. |
we studied the effects of iontophoretically administered mk-801 (50-150 na) on ischemic changes on the ca1 hippocampal field potential. |
1991-03-21 |
2023-08-11 |
rat |
L L Voronin, U Kunt, G Hes. [A quantal analysis of the long-term potentiation of the total postsynaptic neuronal potentials in surviving hippocampal slices]. Neirofiziologiia = Neurophysiology. vol 22. issue 4. 1991-03-18. PMID:2178227. |
excitatory postsynaptic potentials (epsps) from 14 neurons have been recorded in hippocampal slices (area ca1) of guinea pigs after stimulation of stratum radiatum (schaffer collaterals) and stratum oriens. |
1991-03-18 |
2023-08-11 |
Not clear |
J J O'Connor, M J Rowan, R Anwy. Actions of 5-HT1 ligands on excitatory synaptic transmission in the hippocampus of alert rats. British journal of pharmacology. vol 101. issue 1. 1991-03-15. PMID:1980835. |
the effects of 5-hydroxytryptamine1 (5-ht1) ligands on excitatory synaptic transmission were examined in the stratum radiatum of the ca1 region of the dorsal hippocampus of alert, gently restrained, rats. |
1991-03-15 |
2023-08-11 |
rat |
A Seto-Ohshima, E Aoki, R Semba, P C Emson, C W Heizman. Appearance of parvalbumin-specific immunoreactivity in the cerebral cortex and hippocampus of the developing rat and gerbil brain. Histochemistry. vol 94. issue 6. 1991-03-12. PMID:2279955. |
the frequency of bead-like structures on the dendrites of the parvalbumin-positive cells in the ca1 region of the hippocampus was markedly lower in the gerbil; instead, straight non-beaded fibers which ran vertically into the pyramidal layer were stained. |
1991-03-12 |
2023-08-11 |
rat |
R D Blitzer, O Gil, E M Landa. Cholinergic stimulation enhances long-term potentiation in the CA1 region of rat hippocampus. Neuroscience letters. vol 119. issue 2. 1991-03-12. PMID:2280895. |
cholinergic stimulation enhances long-term potentiation in the ca1 region of rat hippocampus. |
1991-03-12 |
2023-08-11 |
rat |
R D Blitzer, O Gil, E M Landa. Cholinergic stimulation enhances long-term potentiation in the CA1 region of rat hippocampus. Neuroscience letters. vol 119. issue 2. 1991-03-12. PMID:2280895. |
the effect of the cholinergic agonist carbachol on a putative substrate for memory (long-term potentiation; ltp) was investigated in slices of rat hippocampus (ca1 region). |
1991-03-12 |
2023-08-11 |
rat |