| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emily K Plowman, Nagheme J Thomas, Jeffrey A Klei. Striatal dopamine depletion induces forelimb motor impairments and disrupts forelimb movement representations within the motor cortex. Journal of Parkinson's disease. vol 1. issue 1. 2014-06-18. PMID:23939260. |
the results clearly show how dysfunction within the basal ganglia thalamocortical loop resulting from nigrostriatal dopamine depletion disrupts corticospinal function. |
2014-06-18 |
2023-08-12 |
rat |
| Daniela Laricchiuta, Alessandra Musella, Silvia Rossi, Diego Centonz. Behavioral and electrophysiological effects of endocannabinoid and dopaminergic systems on salient stimuli. Frontiers in behavioral neuroscience. vol 8. 2014-06-06. PMID:24904335. |
rewarding effects have been related to enhanced dopamine (da) release in corticolimbic and basal ganglia structures. |
2014-06-06 |
2023-08-13 |
mouse |
| Tae Hyuk Kang, Yongjin Park, Joel S Bader, Theodore Friedman. The housekeeping gene hypoxanthine guanine phosphoribosyltransferase (HPRT) regulates multiple developmental and metabolic pathways of murine embryonic stem cell neuronal differentiation. PloS one. vol 8. issue 10. 2014-06-02. PMID:24130677. |
the best recognized neural consequences of hprt deficiency are defective basal ganglia expression of the neurotransmitter dopamine (da) and aberrant da neuronal function. |
2014-06-02 |
2023-08-12 |
human |
| Ji-Hye Yang, Sung-Woo Chung, Joong-Seok Ki. Action tremor associated with lamotrigine monotherapy. Journal of movement disorders. vol 3. issue 1. 2014-05-28. PMID:24868374. |
based on the temporal relationship, it is conceivable that lamotrigine increases serotonin transmission or affects basal ganglia dopamine activity, thereby causing the tremor. |
2014-05-28 |
2023-08-13 |
Not clear |
| Christian Hölsche. Central effects of GLP-1: new opportunities for treatments of neurodegenerative diseases. The Journal of endocrinology. vol 221. issue 1. 2014-05-12. PMID:23999914. |
in animal models of pd, exendin-4 showed protection of dopaminergic neurons in the substantia nigra and prevention of dopamine loss in the basal ganglia while preserving motor control. |
2014-05-12 |
2023-08-12 |
Not clear |
| Jennifer C Felger, Jiyoung Mun, Heather L Kimmel, Jonathon A Nye, Daniel F Drake, Carla R Hernandez, Amanda A Freeman, David B Rye, Mark M Goodman, Leonard L Howell, Andrew H Mille. Chronic interferon-α decreases dopamine 2 receptor binding and striatal dopamine release in association with anhedonia-like behavior in nonhuman primates. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 11. 2014-05-05. PMID:23657438. |
neuroimaging studies in humans have demonstrated that inflammatory cytokines target basal ganglia function and presynaptic dopamine (da), leading to symptoms of depression. |
2014-05-05 |
2023-08-12 |
monkey |
| Regina Rumpel, Mesbah Alam, Alexander Klein, Meltem Özer, Maike Wesemann, Xingxing Jin, Joachim K Krauss, Kerstin Schwabe, Andreas Ratzka, Claudia Groth. Neuronal firing activity and gene expression changes in the subthalamic nucleus after transplantation of dopamine neurons in hemiparkinsonian rats. Neurobiology of disease. vol 59. 2014-05-05. PMID:23938762. |
dopamine (da) depletion in the nigrostriatal system leads to basal ganglia dysfunction both in parkinson's disease (pd) and in 6-hydroxy dopamine (6-ohda)-lesioned rats with neuronal hyperactivity in the subthalamic nucleus (stn), i.e. |
2014-05-05 |
2023-08-12 |
rat |
| Pragathi P Balasubramani, V Srinivasa Chakravarthy, Balaraman Ravindran, Ahmed A Moustaf. An extended reinforcement learning model of basal ganglia to understand the contributions of serotonin and dopamine in risk-based decision making, reward prediction, and punishment learning. Frontiers in computational neuroscience. vol 8. 2014-05-05. PMID:24795614. |
an extended reinforcement learning model of basal ganglia to understand the contributions of serotonin and dopamine in risk-based decision making, reward prediction, and punishment learning. |
2014-05-05 |
2023-08-13 |
Not clear |
| Pragathi P Balasubramani, V Srinivasa Chakravarthy, Balaraman Ravindran, Ahmed A Moustaf. An extended reinforcement learning model of basal ganglia to understand the contributions of serotonin and dopamine in risk-based decision making, reward prediction, and punishment learning. Frontiers in computational neuroscience. vol 8. 2014-05-05. PMID:24795614. |
the model depicts the roles of dopamine (da) and serotonin (5ht) in basal ganglia (bg). |
2014-05-05 |
2023-08-13 |
Not clear |
| Nicola Simola, Micaela Morelli, Giuseppe Frazzitta, Lucia Fra. Role of movement in long-term basal ganglia changes: implications for abnormal motor responses. Frontiers in computational neuroscience. vol 7. 2014-04-22. PMID:24167489. |
abnormal involuntary movements (aims) and dyskinesias elicited by drugs that stimulate dopamine receptors in the basal ganglia are a major issue in the management of parkinson's disease (pd). |
2014-04-22 |
2023-08-12 |
rat |
| Natalie M Doig, Peter J Magill, Paul Apicella, J Paul Bolam, Andrew Sharot. Cortical and thalamic excitation mediate the multiphasic responses of striatal cholinergic interneurons to motivationally salient stimuli. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 8. 2014-04-10. PMID:24553950. |
in primates, tonically active neurons (putative cholinergic interneurons) exhibit multiphasic responses to motivationally salient stimuli that mirror those of midbrain dopamine neurons and together these two systems mediate reward-related learning in basal ganglia circuits. |
2014-04-10 |
2023-08-12 |
rat |
| Maxime Cazorla, Fernanda Delmondes de Carvalho, Muhammad O Chohan, Mariya Shegda, Nao Chuhma, Stephen Rayport, Susanne E Ahmari, Holly Moore, Christoph Kellendon. Dopamine D2 receptors regulate the anatomical and functional balance of basal ganglia circuitry. Neuron. vol 81. issue 1. 2014-03-07. PMID:24411738. |
dopamine d2 receptors regulate the anatomical and functional balance of basal ganglia circuitry. |
2014-03-07 |
2023-08-12 |
mouse |
| Brian D Berman, Mark Hallett, Peter Herscovitch, Kristina Simonya. Striatal dopaminergic dysfunction at rest and during task performance in writer's cramp. Brain : a journal of neurology. vol 136. issue Pt 12. 2014-02-10. PMID:24148273. |
our voxel-based results also suggest that writer's cramp may be associated with reduced striatal dopamine release occuring in the setting of reduced d2/d3 receptor availability and raise the possibility that basal ganglia circuits associated with premotor cortices and those associated with primary motor cortex are differentially affected in primary focal dystonias. |
2014-02-10 |
2023-08-12 |
human |
| Jong H Yoon, Michael J Minzenberg, Sherief Raouf, Mark D'Esposito, Cameron S Carte. Impaired prefrontal-basal ganglia functional connectivity and substantia nigra hyperactivity in schizophrenia. Biological psychiatry. vol 74. issue 2. 2014-01-17. PMID:23290498. |
we undertook this event-related functional magnetic resonance imaging study to test the hypothesis that pfc dysfunction is associated with altered function of and connectivity with dopamine regulating regions of the basal ganglia. |
2014-01-17 |
2023-08-12 |
Not clear |
| Arthur Lebloi. Social modulation of learned behavior by dopamine in the basal ganglia: insights from songbirds. Journal of physiology, Paris. vol 107. issue 3. 2014-01-16. PMID:23032272. |
social modulation of learned behavior by dopamine in the basal ganglia: insights from songbirds. |
2014-01-16 |
2023-08-12 |
Not clear |
| Jennifer C Felger, Li Li, Paul J Marvar, Bobbi J Woolwine, David G Harrison, Charles L Raison, Andrew H Mille. Tyrosine metabolism during interferon-alpha administration: association with fatigue and CSF dopamine concentrations. Brain, behavior, and immunity. vol 31. 2014-01-16. PMID:23072726. |
these effects may be mediated by the actions of ifn-alpha on dopamine (da) metabolism in the basal ganglia. |
2014-01-16 |
2023-08-12 |
human |
| Jolyn N A D'Andrea, Angela M Haffenden, Sarah Furtado, Oksana Suchowersky, Bradley G Goodyea. Degradation of stored movement representations in the Parkinsonian brain and the impact of levodopa. Neuropsychologia. vol 51. issue 7. 2014-01-10. PMID:23591046. |
parkinson's disease (pd) results from the depletion of dopamine and other neurotransmitters within the basal ganglia, and is typically characterized by motor impairment (e.g., bradykinesia) and difficulty initiating voluntary movements. |
2014-01-10 |
2023-08-12 |
human |
| David M Cole, Christian F Beckmann, Nicole Y L Oei, Stephanie Both, Joop M A van Gerven, Serge A R B Rombout. Differential and distributed effects of dopamine neuromodulations on resting-state network connectivity. NeuroImage. vol 78. 2014-01-06. PMID:23603346. |
a basal ganglia rsn displayed both linear and nonlinear effects of dopamine manipulation on functional connectivity, respectively, with lateral frontoparietal and medial frontal neocortical areas. |
2014-01-06 |
2023-08-12 |
human |
| Craig F Ferris, Mathieu Marella, Brian Smerkers, Thomas M Barchet, Benjamin Gershman, Akemi Matsuno-Yagi, Takao Yag. A phenotypic model recapitulating the neuropathology of Parkinson's disease. Brain and behavior. vol 3. issue 4. 2014-01-01. PMID:24381808. |
such a model would show loss of dopamine in the basal ganglia, appearance of lewy bodies, and the early stages of motor dysfunction. |
2014-01-01 |
2023-08-12 |
rat |
| Dorin Yael, Dagmar H Zeef, Daniel Sand, Anan Moran, Donald B Katz, Dana Cohen, Yasin Temel, Izhar Bar-Ga. Haloperidol-induced changes in neuronal activity in the striatum of the freely moving rat. Frontiers in systems neuroscience. vol 7. 2013-12-31. PMID:24379762. |
these findings highlight the heterogeneous striatal effects of tonic dopamine regulation via d2 receptors which potentially enable the treatment of diverse pathological states associated with basal ganglia dysfunction. |
2013-12-31 |
2023-08-12 |
rat |