Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Jennifer C Felger, Jiyoung Mun, Heather L Kimmel, Jonathon A Nye, Daniel F Drake, Carla R Hernandez, Amanda A Freeman, David B Rye, Mark M Goodman, Leonard L Howell, Andrew H Mille. Chronic interferon-α decreases dopamine 2 receptor binding and striatal dopamine release in association with anhedonia-like behavior in nonhuman primates. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 11. 2014-05-05. PMID:23657438. |
neuroimaging studies in humans have demonstrated that inflammatory cytokines target basal ganglia function and presynaptic dopamine (da), leading to symptoms of depression. |
2014-05-05 |
2023-08-12 |
monkey |
Regina Rumpel, Mesbah Alam, Alexander Klein, Meltem Özer, Maike Wesemann, Xingxing Jin, Joachim K Krauss, Kerstin Schwabe, Andreas Ratzka, Claudia Groth. Neuronal firing activity and gene expression changes in the subthalamic nucleus after transplantation of dopamine neurons in hemiparkinsonian rats. Neurobiology of disease. vol 59. 2014-05-05. PMID:23938762. |
dopamine (da) depletion in the nigrostriatal system leads to basal ganglia dysfunction both in parkinson's disease (pd) and in 6-hydroxy dopamine (6-ohda)-lesioned rats with neuronal hyperactivity in the subthalamic nucleus (stn), i.e. |
2014-05-05 |
2023-08-12 |
rat |
Pragathi P Balasubramani, V Srinivasa Chakravarthy, Balaraman Ravindran, Ahmed A Moustaf. An extended reinforcement learning model of basal ganglia to understand the contributions of serotonin and dopamine in risk-based decision making, reward prediction, and punishment learning. Frontiers in computational neuroscience. vol 8. 2014-05-05. PMID:24795614. |
an extended reinforcement learning model of basal ganglia to understand the contributions of serotonin and dopamine in risk-based decision making, reward prediction, and punishment learning. |
2014-05-05 |
2023-08-13 |
Not clear |
Pragathi P Balasubramani, V Srinivasa Chakravarthy, Balaraman Ravindran, Ahmed A Moustaf. An extended reinforcement learning model of basal ganglia to understand the contributions of serotonin and dopamine in risk-based decision making, reward prediction, and punishment learning. Frontiers in computational neuroscience. vol 8. 2014-05-05. PMID:24795614. |
the model depicts the roles of dopamine (da) and serotonin (5ht) in basal ganglia (bg). |
2014-05-05 |
2023-08-13 |
Not clear |
Nicola Simola, Micaela Morelli, Giuseppe Frazzitta, Lucia Fra. Role of movement in long-term basal ganglia changes: implications for abnormal motor responses. Frontiers in computational neuroscience. vol 7. 2014-04-22. PMID:24167489. |
abnormal involuntary movements (aims) and dyskinesias elicited by drugs that stimulate dopamine receptors in the basal ganglia are a major issue in the management of parkinson's disease (pd). |
2014-04-22 |
2023-08-12 |
rat |
Natalie M Doig, Peter J Magill, Paul Apicella, J Paul Bolam, Andrew Sharot. Cortical and thalamic excitation mediate the multiphasic responses of striatal cholinergic interneurons to motivationally salient stimuli. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 8. 2014-04-10. PMID:24553950. |
in primates, tonically active neurons (putative cholinergic interneurons) exhibit multiphasic responses to motivationally salient stimuli that mirror those of midbrain dopamine neurons and together these two systems mediate reward-related learning in basal ganglia circuits. |
2014-04-10 |
2023-08-12 |
rat |
Maxime Cazorla, Fernanda Delmondes de Carvalho, Muhammad O Chohan, Mariya Shegda, Nao Chuhma, Stephen Rayport, Susanne E Ahmari, Holly Moore, Christoph Kellendon. Dopamine D2 receptors regulate the anatomical and functional balance of basal ganglia circuitry. Neuron. vol 81. issue 1. 2014-03-07. PMID:24411738. |
dopamine d2 receptors regulate the anatomical and functional balance of basal ganglia circuitry. |
2014-03-07 |
2023-08-12 |
mouse |
Brian D Berman, Mark Hallett, Peter Herscovitch, Kristina Simonya. Striatal dopaminergic dysfunction at rest and during task performance in writer's cramp. Brain : a journal of neurology. vol 136. issue Pt 12. 2014-02-10. PMID:24148273. |
our voxel-based results also suggest that writer's cramp may be associated with reduced striatal dopamine release occuring in the setting of reduced d2/d3 receptor availability and raise the possibility that basal ganglia circuits associated with premotor cortices and those associated with primary motor cortex are differentially affected in primary focal dystonias. |
2014-02-10 |
2023-08-12 |
human |
Jong H Yoon, Michael J Minzenberg, Sherief Raouf, Mark D'Esposito, Cameron S Carte. Impaired prefrontal-basal ganglia functional connectivity and substantia nigra hyperactivity in schizophrenia. Biological psychiatry. vol 74. issue 2. 2014-01-17. PMID:23290498. |
we undertook this event-related functional magnetic resonance imaging study to test the hypothesis that pfc dysfunction is associated with altered function of and connectivity with dopamine regulating regions of the basal ganglia. |
2014-01-17 |
2023-08-12 |
Not clear |
Arthur Lebloi. Social modulation of learned behavior by dopamine in the basal ganglia: insights from songbirds. Journal of physiology, Paris. vol 107. issue 3. 2014-01-16. PMID:23032272. |
social modulation of learned behavior by dopamine in the basal ganglia: insights from songbirds. |
2014-01-16 |
2023-08-12 |
Not clear |
Jennifer C Felger, Li Li, Paul J Marvar, Bobbi J Woolwine, David G Harrison, Charles L Raison, Andrew H Mille. Tyrosine metabolism during interferon-alpha administration: association with fatigue and CSF dopamine concentrations. Brain, behavior, and immunity. vol 31. 2014-01-16. PMID:23072726. |
these effects may be mediated by the actions of ifn-alpha on dopamine (da) metabolism in the basal ganglia. |
2014-01-16 |
2023-08-12 |
human |
Jolyn N A D'Andrea, Angela M Haffenden, Sarah Furtado, Oksana Suchowersky, Bradley G Goodyea. Degradation of stored movement representations in the Parkinsonian brain and the impact of levodopa. Neuropsychologia. vol 51. issue 7. 2014-01-10. PMID:23591046. |
parkinson's disease (pd) results from the depletion of dopamine and other neurotransmitters within the basal ganglia, and is typically characterized by motor impairment (e.g., bradykinesia) and difficulty initiating voluntary movements. |
2014-01-10 |
2023-08-12 |
human |
David M Cole, Christian F Beckmann, Nicole Y L Oei, Stephanie Both, Joop M A van Gerven, Serge A R B Rombout. Differential and distributed effects of dopamine neuromodulations on resting-state network connectivity. NeuroImage. vol 78. 2014-01-06. PMID:23603346. |
a basal ganglia rsn displayed both linear and nonlinear effects of dopamine manipulation on functional connectivity, respectively, with lateral frontoparietal and medial frontal neocortical areas. |
2014-01-06 |
2023-08-12 |
human |
Craig F Ferris, Mathieu Marella, Brian Smerkers, Thomas M Barchet, Benjamin Gershman, Akemi Matsuno-Yagi, Takao Yag. A phenotypic model recapitulating the neuropathology of Parkinson's disease. Brain and behavior. vol 3. issue 4. 2014-01-01. PMID:24381808. |
such a model would show loss of dopamine in the basal ganglia, appearance of lewy bodies, and the early stages of motor dysfunction. |
2014-01-01 |
2023-08-12 |
rat |
Dorin Yael, Dagmar H Zeef, Daniel Sand, Anan Moran, Donald B Katz, Dana Cohen, Yasin Temel, Izhar Bar-Ga. Haloperidol-induced changes in neuronal activity in the striatum of the freely moving rat. Frontiers in systems neuroscience. vol 7. 2013-12-31. PMID:24379762. |
these findings highlight the heterogeneous striatal effects of tonic dopamine regulation via d2 receptors which potentially enable the treatment of diverse pathological states associated with basal ganglia dysfunction. |
2013-12-31 |
2023-08-12 |
rat |
Claire O'Callaghan, Ahmed A Moustafa, Sanne de Wit, James M Shine, Trevor W Robbins, Simon J G Lewis, Michael Hornberge. Fronto-striatal gray matter contributions to discrimination learning in Parkinson's disease. Frontiers in computational neuroscience. vol 7. 2013-12-30. PMID:24376416. |
using both behavioral patient studies and computational approaches, these deficits have typically been attributed to dopamine imbalance across the basal ganglia. |
2013-12-30 |
2023-08-12 |
Not clear |
Judith P Golden, Joseph A Demaro, Amanda Knoten, Masato Hoshi, Elizabeth Pehek, Eugene M Johnson, Robert W Gereau, Sanjay Jai. Dopamine-dependent compensation maintains motor behavior in mice with developmental ablation of dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 43. 2013-12-23. PMID:24155314. |
in addition, compensatory changes independent of striatal dopamine have been proposed based on pd therapies that modulate nondopaminergic circuits within the basal ganglia. |
2013-12-23 |
2023-08-12 |
mouse |
Ankur Gupta, Pragathi P Balasubramani, V Srinivasa Chakravarth. Computational model of precision grip in Parkinson's disease: a utility based approach. Frontiers in computational neuroscience. vol 7. 2013-12-18. PMID:24348373. |
changes in grip force generation in dopamine-deficient pd conditions strongly suggest contribution of the basal ganglia, a deep brain system having a crucial role in translating dopamine signals to decision making. |
2013-12-18 |
2023-08-12 |
human |
Flavia di Michele, Sabina Luchetti, Giorgio Bernardi, Elena Romeo, Patrizia Longon. Neurosteroid and neurotransmitter alterations in Parkinson's disease. Frontiers in neuroendocrinology. vol 34. issue 2. 2013-12-16. PMID:23563222. |
parkinson's disease (pd) is associated with a massive loss of dopaminergic cells in the substantia nigra leading to dopamine hypofunction and alteration of the basal ganglia circuitry. |
2013-12-16 |
2023-08-12 |
human |
Xiaoxi Zhuang, Pietro Mazzoni, Un Jung Kan. The role of neuroplasticity in dopaminergic therapy for Parkinson disease. Nature reviews. Neurology. vol 9. issue 5. 2013-12-09. PMID:23588357. |
we place these findings in the context of the role of dopamine in basal ganglia function and corticostriatal plasticity, and provide a new framework suggesting that therapies that enhance the ldr could be more effective than those targeting the sdr. |
2013-12-09 |
2023-08-12 |
Not clear |