| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rodrigo Bainy Leal, Mark William Lopes, Douglas Affonso Formolo, Cristiane Ribeiro de Carvalho, Alexandre Ademar Hoeller, Alexandra Latini, Daniel Santos Sousa, Peter Wolf, Rui Daniel Prediger, Zuner Assis Bortolotto, Marcelo Neves Linhares, Kátia Lin, Roger Wal. Amygdala levels of the GluA1 subunit of glutamate receptors and its phosphorylation state at serine 845 in the anterior hippocampus are biomarkers of ictal fear but not anxiety. Molecular psychiatry. vol 25. issue 3. 2021-01-14. PMID:29880883. |
amygdala levels of the glua1 subunit of glutamate receptors and its phosphorylation state at serine 845 in the anterior hippocampus are biomarkers of ictal fear but not anxiety. |
2021-01-14 |
2023-08-13 |
human |
| Shengyan Xi, Guangxin Yue, Yueyun Liu, Yanan Wang, Yingkun Qiu, Zhigeng Li, Pei Ma, Tiegang Liu, Youming Jiang, Yuan Liang, Qun Liu, Jing Shi, Jiaxu Chen, Lifeng Yu. Free Wanderer Powder regulates AMPA receptor homeostasis in chronic restraint stress-induced rat model of depression with liver-depression and spleen-deficiency syndrome. Aging. vol 12. issue 19. 2020-12-19. PMID:33052137. |
expressions of c-fos and ampa-type glutamate receptor subunits glur1-3 in hippocampus ca1, ca3, dg and amygdala bla were detected by immunohistochemistry, western blot and rt-pcr, respectively. |
2020-12-19 |
2023-08-13 |
rat |
| Shengyan Xi, Guangxin Yue, Yueyun Liu, Yanan Wang, Yingkun Qiu, Zhigeng Li, Pei Ma, Tiegang Liu, Youming Jiang, Yuan Liang, Qun Liu, Jing Shi, Jiaxu Chen, Lifeng Yu. Free Wanderer Powder regulates AMPA receptor homeostasis in chronic restraint stress-induced rat model of depression with liver-depression and spleen-deficiency syndrome. Aging. vol 12. issue 19. 2020-12-19. PMID:33052137. |
together, these results suggest that fwp contains effective constituents and alleviates depression with ldsds by regulating ampa-type glutamate receptor homeostasis in amygdala and hippocampus. |
2020-12-19 |
2023-08-13 |
rat |
| Fariba Khodagholi, Ali Maleki, Fereshteh Motamedi, Maryam Alsadat Mousavi, Shahrbanoo Rafiei, Mehdi Moslem. Oxytocin Prevents the Development of 3-NP-Induced Anxiety and Depression in Male and Female Rats: Possible Interaction of OXTR and mGluR2. Cellular and molecular neurobiology. 2020-11-17. PMID:33201416. |
anxiety- and depression-like behaviors as well as the levels of oxytocin receptor (oxtr), metabotropic glutamate receptor (mglur) 2, mglur5, and glutathione (gsh) were measured in striatum, hippocampus, prefrontal cortex, and amygdala. |
2020-11-17 |
2023-08-13 |
rat |
| G C Gregoriou, S D Patel, B L Winters, E E Bagle. Neprilysin Controls the Synaptic Activity of Neuropeptides in the Intercalated Cells of the Amygdala. Molecular pharmacology. vol 98. issue 4. 2020-11-06. PMID:32606204. |
using inhibition of glutamate release onto the intercalated cells of the amygdala as an assay for enkephalin activity, we applied specific peptidase inhibitors to determine which peptidase(s) regulate enkephalin signaling in this region. |
2020-11-06 |
2023-08-13 |
rat |
| Elizabeth A Fucich, Jacques P Mayeux, M Adrienne McGinn, Nicholas W Gilpin, Scott Edwards, Patricia E Molin. A Novel Role for the Endocannabinoid System in Ameliorating Motivation for Alcohol Drinking and Negative Behavioral Affect after Traumatic Brain Injury in Rats. Journal of neurotrauma. vol 36. issue 11. 2020-10-26. PMID:30638118. |
spatial memory (y-maze), anxiety-like behavior (open field), alcohol motivation (progressive ratio responding), and mechanosensitivity (von frey) were measured 3-10 days post-injury, and ventral striatum (vs) and central amygdala (cea) tissue were collected for western blot analysis of phosphorylated glutamate receptor subunit 1 (glur1) and glucocorticoid receptor (gr). |
2020-10-26 |
2023-08-13 |
rat |
| Jeffrey Parrilla Carrero, Kris F Kaigler, George H Hartshorn, Jim R Fadel, Marlene A Wilso. Mu opioid receptor regulation of glutamate efflux in the central amygdala in response to predator odor. Neurobiology of stress. vol 11. 2020-10-23. PMID:31832510. |
mu opioid receptor regulation of glutamate efflux in the central amygdala in response to predator odor. |
2020-10-23 |
2023-08-13 |
rat |
| Dominic A Gioia, Nancy Alexander, Brian A McCoo. Ethanol Mediated Inhibition of Synaptic Vesicle Recycling at Amygdala Glutamate Synapses Is Dependent upon Munc13-2. Frontiers in neuroscience. vol 11. 2020-10-01. PMID:28785200. |
ethanol mediated inhibition of synaptic vesicle recycling at amygdala glutamate synapses is dependent upon munc13-2. |
2020-10-01 |
2023-08-13 |
mouse |
| Liang Kong, Yan Zhao, Wen-Juan Zhou, Hui Yu, Shuai-Wen Teng, Qi Guo, Zheyu Chen, Yue Wan. Direct Neuronal Glucose Uptake Is Required for Contextual Fear Acquisition in the Dorsal Hippocampus. Frontiers in molecular neuroscience. vol 10. 2020-10-01. PMID:29209168. |
strikingly, microinjection of a glucose transporter (glut) inhibitor into the dh decreased freezing values during cfc training and 1 h later, while injection of a monocarboxylate transporter (mct) inhibitor into the amygdala also reduced freezing values. |
2020-10-01 |
2023-08-13 |
Not clear |
| Veronica M Piggott, Kelly E Bosse, Michael J Lisieski, John A Strader, Jeffrey A Stanley, Alana C Conti, Farhad Ghoddoussi, Shane A Perrin. Single-Prolonged Stress Impairs Prefrontal Cortex Control of Amygdala and Striatum in Rats. Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:31114487. |
clinical studies show hypoactivity in the mpfc and hyperactivity in the amygdala and striatum of ptsd patients, which has been associated with decreased mpfc glutamate levels. |
2020-10-01 |
2023-08-13 |
rat |
| Enrico Ullmann, Seth W Perry, Julio Licinio, Ma-Li Wong, Eliyahu Dremencov, Evgenii L Zavjalov, Oleg B Shevelev, Nikita V Khotskin, Galina V Koncevaya, Anna S Khotshkina, Mikhail P Moshkin, Maxim S Lapshin, Maria V Komelkova, Inna V Feklicheva, Olga B Tseilikman, Olga P Cherkasova, Kamaldeep S Bhui, Edgar Jones, Clemens Kirschbaum, Stefan R Bornstein, Vadim Tseilikma. From Allostatic Load to Allostatic State-An Endogenous Sympathetic Strategy to Deal With Chronic Anxiety and Stress? Frontiers in behavioral neuroscience. vol 13. 2020-09-30. PMID:30967764. |
in the same chronic pss paradigm, aor rats also have higher lactate and lower glutamate levels in amygdala but not in control-region hippocampus vs. pdr rats. |
2020-09-30 |
2023-08-13 |
rat |
| Joshua A Beitchman, Daniel R Griffiths, Yerin Hur, Sarah B Ogle, Caitlin E Bromberg, Helena W Morrison, Jonathan Lifshitz, P David Adelson, Theresa Currier Thoma. Experimental Traumatic Brain Injury Induces Chronic Glutamatergic Dysfunction in Amygdala Circuitry Known to Regulate Anxiety-Like Behavior. Frontiers in neuroscience. vol 13. 2020-09-28. PMID:32038140. |
we hypothesize that the development of tbi-induced anxiety-like behavior in an experimental model of tbi is mediated by changes in glutamate neurotransmission within the amygdala. |
2020-09-28 |
2023-08-13 |
rat |
| Joshua A Beitchman, Daniel R Griffiths, Yerin Hur, Sarah B Ogle, Caitlin E Bromberg, Helena W Morrison, Jonathan Lifshitz, P David Adelson, Theresa Currier Thoma. Experimental Traumatic Brain Injury Induces Chronic Glutamatergic Dysfunction in Amygdala Circuitry Known to Regulate Anxiety-Like Behavior. Frontiers in neuroscience. vol 13. 2020-09-28. PMID:32038140. |
anxiety-like behavior was assessed at 7 and 28 days post-injury (dpi) followed by assessment of real-time glutamate neurotransmission in the basolateral amygdala (bla) and central nucleus of the amygdala (cea) using glutamate-selective microelectrode arrays. |
2020-09-28 |
2023-08-13 |
rat |
| Kevin Gley, Eduard Murani, Fiete Haack, Nares Trakooljul, Manuela Zebunke, Birger Puppe, Klaus Wimmers, Siriluck Ponsuksil. Haplotypes of coping behavior associated QTL regions reveal distinct transcript profiles in amygdala and hippocampus. Behavioural brain research. vol 372. 2020-09-10. PMID:31202863. |
pathway analysis revealed il-8 signaling, nf-κb signaling, glutamate and gaba metabolism, glucocorticoid receptor signaling and chemokine signaling in the amygdala and ephrin receptor signaling, as well as nf-κb signaling in the hippocampus. |
2020-09-10 |
2023-08-13 |
Not clear |
| Bahardokht Tolou-Dabbaghian, Ladan Delphi, Ameneh Rezayo. Blockade of NMDA Receptors and Nitric Oxide Synthesis Potentiated Morphine-Induced Anti-Allodynia via Attenuating Pain-Related Amygdala pCREB/CREB Signaling Pathway. The journal of pain. vol 20. issue 8. 2020-09-08. PMID:30707953. |
moreover, the glutamate nmda receptors and nitric oxide system in the amygdala may be involved in morphine-induced anti-allodynia. |
2020-09-08 |
2023-08-13 |
rat |
| Jocelyn M Breton, Annabelle R Charbit, Benjamin J Snyder, Peter T K Fong, Elayne V Dias, Patricia Himmels, Hagar Lock, Elyssa B Margoli. Relative contributions and mapping of ventral tegmental area dopamine and GABA neurons by projection target in the rat. The Journal of comparative neurology. vol 527. issue 5. 2020-07-28. PMID:30393861. |
here, we combined retrograde tracing with immunocytochemistry against tyrosine hydroxylase (th) or glutamate decarboxylase (gad) to systematically compare the proportion of dopaminergic and gabaergic vta projections to 10 target nuclei: anterior cingulate, prelimbic, and infralimbic cortex; nucleus accumbens core, medial shell, and lateral shell; anterior and posterior basolateral amygdala; ventral pallidum; and periaqueductal gray. |
2020-07-28 |
2023-08-13 |
rat |
| Xia Qin, Ye He, Na Wang, Jia-Xin Zou, Yong-Mei Zhang, Jun-Li Cao, Bing-Xing Pan, Wen-Hua Zhan. Moderate maternal separation mitigates the altered synaptic transmission and neuronal activation in amygdala by chronic stress in adult mice. Molecular brain. vol 12. issue 1. 2020-07-10. PMID:31849343. |
here, we observed that moderate maternal separation (ms) from postnatal day 3 to day 21 (d3-21, 1 h per day) significantly alleviated the increased anxiety-like behavior induced by chronic social defeat stress (csds) in adulthood, suggesting an obvious inoculative effect of moderate ms. further studies revealed that ms prevented csds-evoked augmentation of glutamatergic transmission onto principal neurons (pns) in the basolateral amygdala (bla) by inhibiting presynaptic glutamate release. |
2020-07-10 |
2023-08-13 |
mouse |
| Allison C Nugent, Cristan Farmer, Jennifer W Evans, Sam L Snider, Dipavo Banerjee, Carlos A Zarat. Multimodal imaging reveals a complex pattern of dysfunction in corticolimbic pathways in major depressive disorder. Human brain mapping. vol 40. issue 13. 2020-04-13. PMID:31179620. |
significant differences in the correlation between medial prefrontal glutamate concentrations and fa were also observed between mdd and healthy participants along tracts connecting the sgacc and right amygdala; healthy participants exhibited a strong correlation but mdd participants showed no such relationship. |
2020-04-13 |
2023-08-13 |
human |
| Shaun Yon-Seng Khoo, Mandy Rita LeCocq, Ghislaine E Deyab, Nadia Chaudhr. Context and topography determine the role of basolateral amygdala metabotropic glutamate receptor 5 in appetitive Pavlovian responding. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 9. 2020-03-17. PMID:30758331. |
context and topography determine the role of basolateral amygdala metabotropic glutamate receptor 5 in appetitive pavlovian responding. |
2020-03-17 |
2023-08-13 |
Not clear |
| Aparna Rajagopalan, Nadine Schweizer, Karin Nordenankar, Sultana Nilufar Jahan, Lina Emilsson, Åsa Wallén-Mackenzi. Reduced gene expression levels of Munc13-1 and additional components of the presynaptic exocytosis machinery upon conditional targeting of Vglut2 in the adolescent mouse. Synapse (New York, N.Y.). vol 68. issue 12. 2019-11-20. PMID:25139798. |
mice carrying a spatiotemporal restriction in the expression of the vesicular glutamate transporter 2 (vglut2; aka slc17a6) in the cortex, amygdala and hippocampal subiculum from the third postnatal week show a strong anxiolytic phenotype and certain behavioral correlates of schizophrenia. |
2019-11-20 |
2023-08-13 |
mouse |