Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
M E Chávez-Pichardo, D Y Reyes-Bravo, M S Mendoza-Trejo, A G Marín-López, M Giordano, N Hernández-Chan, K Domínguez-Marchan, L C Ortega-Rosales, V M Rodrígue. Brain alterations in GABA, glutamate and glutamine markers after chronic atrazine exposure in the male albino rat. Archives of toxicology. vol 94. issue 9. 2021-06-16. PMID:32561961. |
gaba, glutamate, and glutamine levels were differentially altered in brain regions related to nigrostriatal and mesolimbic systems, the amygdala, and the prefrontal cortex. |
2021-06-16 |
2023-08-13 |
rat |
Soundarrajan Edwin Jeyaraj, Karunanithi Sivasangari, Jesús García-Colunga, Koilmani Emmanuvel Raja. Environmental enrichment enhances sociability by regulating glutamate signaling pathway through GR by epigenetic mechanisms in amygdala of Indian field mice Mus booduga. General and comparative endocrinology. vol 300. 2021-06-16. PMID:33017584. |
environmental enrichment enhances sociability by regulating glutamate signaling pathway through gr by epigenetic mechanisms in amygdala of indian field mice mus booduga. |
2021-06-16 |
2023-08-13 |
mouse |
Ivanka Savi. MRS Shows Regionally Increased Glutamate Levels among Patients with Exhaustion Syndrome Due to Occupational Stress. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 6. 2021-05-04. PMID:32195540. |
these data show the key role of glutamate in stress-related neuronal signaling and the specific roles of the amygdala and acc/mpfc. |
2021-05-04 |
2023-08-13 |
Not clear |
Guan-Hsun Wang, Ping Chou, Shu-Wei Hsueh, Ya-Chin Yang, Chung-Chin Ku. Glutamate transmission rather than cellular pacemaking propels excitatory-inhibitory resonance for ictogenesis in amygdala. Neurobiology of disease. vol 148. 2021-03-23. PMID:33221531. |
glutamate transmission rather than cellular pacemaking propels excitatory-inhibitory resonance for ictogenesis in amygdala. |
2021-03-23 |
2023-08-13 |
Not clear |
Amir Segev, Masaya Yanagi, Daniel Scott, Sarah A Southcott, Jacob M Lister, Chunfeng Tan, Wei Li, Shari G Birnbaum, Saïd Kourrich, Carol A Tamming. Reduced GluN1 in mouse dentate gyrus is associated with CA3 hyperactivity and psychosis-like behaviors. Molecular psychiatry. vol 25. issue 11. 2021-03-15. PMID:30038231. |
dg-glun1 ko mice show ca3 cellular hyperactivity, detected using two approaches: (1) increased excitatory glutamate transmission at mossy fibers (mf)-ca3 synapses, and (2) an increased number of cfos-activated pyramidal neurons in ca3, an outcome that appears to project downstream to ca1 and basolateral amygdala (bla). |
2021-03-15 |
2023-08-13 |
mouse |
Neda Valian, Marziyeh Sorayya, Sareh Asadi, Fatemeh Sherafati, Ali Ershad, Sara Savaheli, Abolhassan Ahmadian. Preconditioning by ultra-low dose of tramadol reduces the severity of tramadol-induced seizure: Contribution of glutamate receptors. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 133. 2021-02-24. PMID:33249277. |
the expression of norbin (as a regulator of metabotropic glutamate receptor 5), calponin3 (as a regulator of excitatory synaptic markers), nr1 (nmda receptor subunit 1) and glur1 (ampa receptor subunit 1) was measured in hippocampus, prefrontal cortex (pfc) and amygdala. |
2021-02-24 |
2023-08-13 |
rat |
Rodrigo Bainy Leal, Mark William Lopes, Douglas Affonso Formolo, Cristiane Ribeiro de Carvalho, Alexandre Ademar Hoeller, Alexandra Latini, Daniel Santos Sousa, Peter Wolf, Rui Daniel Prediger, Zuner Assis Bortolotto, Marcelo Neves Linhares, Kátia Lin, Roger Wal. Amygdala levels of the GluA1 subunit of glutamate receptors and its phosphorylation state at serine 845 in the anterior hippocampus are biomarkers of ictal fear but not anxiety. Molecular psychiatry. vol 25. issue 3. 2021-01-14. PMID:29880883. |
amygdala levels of the glua1 subunit of glutamate receptors and its phosphorylation state at serine 845 in the anterior hippocampus are biomarkers of ictal fear but not anxiety. |
2021-01-14 |
2023-08-13 |
human |
Shengyan Xi, Guangxin Yue, Yueyun Liu, Yanan Wang, Yingkun Qiu, Zhigeng Li, Pei Ma, Tiegang Liu, Youming Jiang, Yuan Liang, Qun Liu, Jing Shi, Jiaxu Chen, Lifeng Yu. Free Wanderer Powder regulates AMPA receptor homeostasis in chronic restraint stress-induced rat model of depression with liver-depression and spleen-deficiency syndrome. Aging. vol 12. issue 19. 2020-12-19. PMID:33052137. |
expressions of c-fos and ampa-type glutamate receptor subunits glur1-3 in hippocampus ca1, ca3, dg and amygdala bla were detected by immunohistochemistry, western blot and rt-pcr, respectively. |
2020-12-19 |
2023-08-13 |
rat |
Shengyan Xi, Guangxin Yue, Yueyun Liu, Yanan Wang, Yingkun Qiu, Zhigeng Li, Pei Ma, Tiegang Liu, Youming Jiang, Yuan Liang, Qun Liu, Jing Shi, Jiaxu Chen, Lifeng Yu. Free Wanderer Powder regulates AMPA receptor homeostasis in chronic restraint stress-induced rat model of depression with liver-depression and spleen-deficiency syndrome. Aging. vol 12. issue 19. 2020-12-19. PMID:33052137. |
together, these results suggest that fwp contains effective constituents and alleviates depression with ldsds by regulating ampa-type glutamate receptor homeostasis in amygdala and hippocampus. |
2020-12-19 |
2023-08-13 |
rat |
Fariba Khodagholi, Ali Maleki, Fereshteh Motamedi, Maryam Alsadat Mousavi, Shahrbanoo Rafiei, Mehdi Moslem. Oxytocin Prevents the Development of 3-NP-Induced Anxiety and Depression in Male and Female Rats: Possible Interaction of OXTR and mGluR2. Cellular and molecular neurobiology. 2020-11-17. PMID:33201416. |
anxiety- and depression-like behaviors as well as the levels of oxytocin receptor (oxtr), metabotropic glutamate receptor (mglur) 2, mglur5, and glutathione (gsh) were measured in striatum, hippocampus, prefrontal cortex, and amygdala. |
2020-11-17 |
2023-08-13 |
rat |
G C Gregoriou, S D Patel, B L Winters, E E Bagle. Neprilysin Controls the Synaptic Activity of Neuropeptides in the Intercalated Cells of the Amygdala. Molecular pharmacology. vol 98. issue 4. 2020-11-06. PMID:32606204. |
using inhibition of glutamate release onto the intercalated cells of the amygdala as an assay for enkephalin activity, we applied specific peptidase inhibitors to determine which peptidase(s) regulate enkephalin signaling in this region. |
2020-11-06 |
2023-08-13 |
rat |
Elizabeth A Fucich, Jacques P Mayeux, M Adrienne McGinn, Nicholas W Gilpin, Scott Edwards, Patricia E Molin. A Novel Role for the Endocannabinoid System in Ameliorating Motivation for Alcohol Drinking and Negative Behavioral Affect after Traumatic Brain Injury in Rats. Journal of neurotrauma. vol 36. issue 11. 2020-10-26. PMID:30638118. |
spatial memory (y-maze), anxiety-like behavior (open field), alcohol motivation (progressive ratio responding), and mechanosensitivity (von frey) were measured 3-10 days post-injury, and ventral striatum (vs) and central amygdala (cea) tissue were collected for western blot analysis of phosphorylated glutamate receptor subunit 1 (glur1) and glucocorticoid receptor (gr). |
2020-10-26 |
2023-08-13 |
rat |
Jeffrey Parrilla Carrero, Kris F Kaigler, George H Hartshorn, Jim R Fadel, Marlene A Wilso. Mu opioid receptor regulation of glutamate efflux in the central amygdala in response to predator odor. Neurobiology of stress. vol 11. 2020-10-23. PMID:31832510. |
mu opioid receptor regulation of glutamate efflux in the central amygdala in response to predator odor. |
2020-10-23 |
2023-08-13 |
rat |
Dominic A Gioia, Nancy Alexander, Brian A McCoo. Ethanol Mediated Inhibition of Synaptic Vesicle Recycling at Amygdala Glutamate Synapses Is Dependent upon Munc13-2. Frontiers in neuroscience. vol 11. 2020-10-01. PMID:28785200. |
ethanol mediated inhibition of synaptic vesicle recycling at amygdala glutamate synapses is dependent upon munc13-2. |
2020-10-01 |
2023-08-13 |
mouse |
Liang Kong, Yan Zhao, Wen-Juan Zhou, Hui Yu, Shuai-Wen Teng, Qi Guo, Zheyu Chen, Yue Wan. Direct Neuronal Glucose Uptake Is Required for Contextual Fear Acquisition in the Dorsal Hippocampus. Frontiers in molecular neuroscience. vol 10. 2020-10-01. PMID:29209168. |
strikingly, microinjection of a glucose transporter (glut) inhibitor into the dh decreased freezing values during cfc training and 1 h later, while injection of a monocarboxylate transporter (mct) inhibitor into the amygdala also reduced freezing values. |
2020-10-01 |
2023-08-13 |
Not clear |
Veronica M Piggott, Kelly E Bosse, Michael J Lisieski, John A Strader, Jeffrey A Stanley, Alana C Conti, Farhad Ghoddoussi, Shane A Perrin. Single-Prolonged Stress Impairs Prefrontal Cortex Control of Amygdala and Striatum in Rats. Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:31114487. |
clinical studies show hypoactivity in the mpfc and hyperactivity in the amygdala and striatum of ptsd patients, which has been associated with decreased mpfc glutamate levels. |
2020-10-01 |
2023-08-13 |
rat |
Enrico Ullmann, Seth W Perry, Julio Licinio, Ma-Li Wong, Eliyahu Dremencov, Evgenii L Zavjalov, Oleg B Shevelev, Nikita V Khotskin, Galina V Koncevaya, Anna S Khotshkina, Mikhail P Moshkin, Maxim S Lapshin, Maria V Komelkova, Inna V Feklicheva, Olga B Tseilikman, Olga P Cherkasova, Kamaldeep S Bhui, Edgar Jones, Clemens Kirschbaum, Stefan R Bornstein, Vadim Tseilikma. From Allostatic Load to Allostatic State-An Endogenous Sympathetic Strategy to Deal With Chronic Anxiety and Stress? Frontiers in behavioral neuroscience. vol 13. 2020-09-30. PMID:30967764. |
in the same chronic pss paradigm, aor rats also have higher lactate and lower glutamate levels in amygdala but not in control-region hippocampus vs. pdr rats. |
2020-09-30 |
2023-08-13 |
rat |
Joshua A Beitchman, Daniel R Griffiths, Yerin Hur, Sarah B Ogle, Caitlin E Bromberg, Helena W Morrison, Jonathan Lifshitz, P David Adelson, Theresa Currier Thoma. Experimental Traumatic Brain Injury Induces Chronic Glutamatergic Dysfunction in Amygdala Circuitry Known to Regulate Anxiety-Like Behavior. Frontiers in neuroscience. vol 13. 2020-09-28. PMID:32038140. |
we hypothesize that the development of tbi-induced anxiety-like behavior in an experimental model of tbi is mediated by changes in glutamate neurotransmission within the amygdala. |
2020-09-28 |
2023-08-13 |
rat |
Joshua A Beitchman, Daniel R Griffiths, Yerin Hur, Sarah B Ogle, Caitlin E Bromberg, Helena W Morrison, Jonathan Lifshitz, P David Adelson, Theresa Currier Thoma. Experimental Traumatic Brain Injury Induces Chronic Glutamatergic Dysfunction in Amygdala Circuitry Known to Regulate Anxiety-Like Behavior. Frontiers in neuroscience. vol 13. 2020-09-28. PMID:32038140. |
anxiety-like behavior was assessed at 7 and 28 days post-injury (dpi) followed by assessment of real-time glutamate neurotransmission in the basolateral amygdala (bla) and central nucleus of the amygdala (cea) using glutamate-selective microelectrode arrays. |
2020-09-28 |
2023-08-13 |
rat |
Kevin Gley, Eduard Murani, Fiete Haack, Nares Trakooljul, Manuela Zebunke, Birger Puppe, Klaus Wimmers, Siriluck Ponsuksil. Haplotypes of coping behavior associated QTL regions reveal distinct transcript profiles in amygdala and hippocampus. Behavioural brain research. vol 372. 2020-09-10. PMID:31202863. |
pathway analysis revealed il-8 signaling, nf-κb signaling, glutamate and gaba metabolism, glucocorticoid receptor signaling and chemokine signaling in the amygdala and ephrin receptor signaling, as well as nf-κb signaling in the hippocampus. |
2020-09-10 |
2023-08-13 |
Not clear |