| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bahardokht Tolou-Dabbaghian, Ladan Delphi, Ameneh Rezayo. Blockade of NMDA Receptors and Nitric Oxide Synthesis Potentiated Morphine-Induced Anti-Allodynia via Attenuating Pain-Related Amygdala pCREB/CREB Signaling Pathway. The journal of pain. vol 20. issue 8. 2020-09-08. PMID:30707953. |
moreover, the glutamate nmda receptors and nitric oxide system in the amygdala may be involved in morphine-induced anti-allodynia. |
2020-09-08 |
2023-08-13 |
rat |
| Jocelyn M Breton, Annabelle R Charbit, Benjamin J Snyder, Peter T K Fong, Elayne V Dias, Patricia Himmels, Hagar Lock, Elyssa B Margoli. Relative contributions and mapping of ventral tegmental area dopamine and GABA neurons by projection target in the rat. The Journal of comparative neurology. vol 527. issue 5. 2020-07-28. PMID:30393861. |
here, we combined retrograde tracing with immunocytochemistry against tyrosine hydroxylase (th) or glutamate decarboxylase (gad) to systematically compare the proportion of dopaminergic and gabaergic vta projections to 10 target nuclei: anterior cingulate, prelimbic, and infralimbic cortex; nucleus accumbens core, medial shell, and lateral shell; anterior and posterior basolateral amygdala; ventral pallidum; and periaqueductal gray. |
2020-07-28 |
2023-08-13 |
rat |
| Xia Qin, Ye He, Na Wang, Jia-Xin Zou, Yong-Mei Zhang, Jun-Li Cao, Bing-Xing Pan, Wen-Hua Zhan. Moderate maternal separation mitigates the altered synaptic transmission and neuronal activation in amygdala by chronic stress in adult mice. Molecular brain. vol 12. issue 1. 2020-07-10. PMID:31849343. |
here, we observed that moderate maternal separation (ms) from postnatal day 3 to day 21 (d3-21, 1 h per day) significantly alleviated the increased anxiety-like behavior induced by chronic social defeat stress (csds) in adulthood, suggesting an obvious inoculative effect of moderate ms. further studies revealed that ms prevented csds-evoked augmentation of glutamatergic transmission onto principal neurons (pns) in the basolateral amygdala (bla) by inhibiting presynaptic glutamate release. |
2020-07-10 |
2023-08-13 |
mouse |
| Allison C Nugent, Cristan Farmer, Jennifer W Evans, Sam L Snider, Dipavo Banerjee, Carlos A Zarat. Multimodal imaging reveals a complex pattern of dysfunction in corticolimbic pathways in major depressive disorder. Human brain mapping. vol 40. issue 13. 2020-04-13. PMID:31179620. |
significant differences in the correlation between medial prefrontal glutamate concentrations and fa were also observed between mdd and healthy participants along tracts connecting the sgacc and right amygdala; healthy participants exhibited a strong correlation but mdd participants showed no such relationship. |
2020-04-13 |
2023-08-13 |
human |
| Shaun Yon-Seng Khoo, Mandy Rita LeCocq, Ghislaine E Deyab, Nadia Chaudhr. Context and topography determine the role of basolateral amygdala metabotropic glutamate receptor 5 in appetitive Pavlovian responding. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 9. 2020-03-17. PMID:30758331. |
context and topography determine the role of basolateral amygdala metabotropic glutamate receptor 5 in appetitive pavlovian responding. |
2020-03-17 |
2023-08-13 |
Not clear |
| Aparna Rajagopalan, Nadine Schweizer, Karin Nordenankar, Sultana Nilufar Jahan, Lina Emilsson, Åsa Wallén-Mackenzi. Reduced gene expression levels of Munc13-1 and additional components of the presynaptic exocytosis machinery upon conditional targeting of Vglut2 in the adolescent mouse. Synapse (New York, N.Y.). vol 68. issue 12. 2019-11-20. PMID:25139798. |
mice carrying a spatiotemporal restriction in the expression of the vesicular glutamate transporter 2 (vglut2; aka slc17a6) in the cortex, amygdala and hippocampal subiculum from the third postnatal week show a strong anxiolytic phenotype and certain behavioral correlates of schizophrenia. |
2019-11-20 |
2023-08-13 |
mouse |
| Mazahir T Hasan, Ferdinand Althammer, Miriam Silva da Gouveia, Stephanie Goyon, Marina Eliava, Arthur Lefevre, Damien Kerspern, Jonas Schimmer, Androniki Raftogianni, Jerome Wahis, H Sophie Knobloch-Bollmann, Yan Tang, Xinying Liu, Apar Jain, Virginie Chavant, Yannick Goumon, Jan-Marek Weislogel, René Hurlemann, Sabine C Herpertz, Claudia Pitzer, Pascal Darbon, Godwin K Dogbevia, Ilaria Bertocchi, Matthew E Larkum, Rolf Sprengel, Hilmar Bading, Alexandre Charlet, Valery Grinevic. A Fear Memory Engram and Its Plasticity in the Hypothalamic Oxytocin System. Neuron. vol 103. issue 1. 2019-10-22. PMID:31104950. |
intriguingly, ot cell terminals of fear-experienced rats displayed enhanced glutamate release in the amygdala. |
2019-10-22 |
2023-08-13 |
rat |
| Shaona Acharjee, Megan Verbeek, Carlos D Gomez, Kanchan Bisht, Benjamin Lee, Lucas Benoit, Keith A Sharkey, Adrienne Benediktsson, Marie-Eve Tremblay, Quentin J Pittma. Reduced Microglial Activity and Enhanced Glutamate Transmission in the Basolateral Amygdala in Early CNS Autoimmunity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 42. 2019-10-10. PMID:30185466. |
reduced microglial activity and enhanced glutamate transmission in the basolateral amygdala in early cns autoimmunity. |
2019-10-10 |
2023-08-13 |
mouse |
| Maria A De Luca, Matthew W Buczynski, Gaetano Di Chiar. Loren Parsons' contribution to addiction neurobiology. Addiction biology. vol 23. issue 6. 2019-10-07. PMID:29949237. |
larry also applied microdialysis to study gaba and glutamate's role in ethanol dependence and heroin reinforcement, providing in vivo evidence for a sensitization of corticotropin-releasing factor-dependent release of gaba in the central amygdala in withdrawal from chronic ethanol and for a reduction of gaba transmission in the ventral pallidum in heroin but not cocaine intravenous self-administration. |
2019-10-07 |
2023-08-13 |
Not clear |
| Kathleen J Maheras, Marcello Peppi, Farhad Ghoddoussi, Matthew P Galloway, Shane A Perrine, Alexander Go. Absence of Claudin 11 in CNS Myelin Perturbs Behavior and Neurotransmitter Levels in Mice. Scientific reports. vol 8. issue 1. 2019-09-16. PMID:29491447. |
importantly, these behaviors are associated with increased transmission time along myelinated fibers as well as glutamate and gaba neurotransmitter imbalances in auditory brainstem and amygdala, in the absence of neurodegeneration. |
2019-09-16 |
2023-08-13 |
mouse |
| Erratum: Acharjee et al., "Reduced Microglial Activity and Enhanced Glutamate Transmission in the Basolateral Amygdala in Early CNS Autoimmunity". The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 25. 2019-08-16. PMID:31061087. |
erratum: acharjee et al., "reduced microglial activity and enhanced glutamate transmission in the basolateral amygdala in early cns autoimmunity". |
2019-08-16 |
2023-08-13 |
Not clear |
| Y M Geng, J T Xue, J P Su, H Y L. Molecular mechanism of action of valproate acid alone or in combination with chlorpromazine in the epigenetic regulation of schizophrenia. Journal of biological regulators and homeostatic agents. vol 32. issue 6. 2019-06-14. PMID:30574748. |
the real time pcr assay was used to detect the mrna expression changes of gaba system gene [gabbr1 (gaba b receptor 1)], gad1 (glutamic acid decarboxylase1), gad2 (glutamic acid decarboxylase2), lipase metabolic key enzyme lpl (lipoprotein lipase) gene, glutamate neurotransmitter gene gria2 (ampa subtype glutamate receptors 2), inward rectifier potassium channel members kcnj4 (potassium voltage-gated channel subfamily j member 4) and neuropeptide signal gene tac1 (tachykinin precursor 1,tac1) in four brain regions: the prefrontal cortex (pc), the amygdala (am), the caudate-putamen (cpu) and the hippocampus (hip). |
2019-06-14 |
2023-08-13 |
rat |
| Sahel Kumar, Zsofia Gal, Xenia Gonda, Robin J Huse, Gabriella Juhasz, Gyorgy Bagdy, Peter Petschne. Transcriptomic changes following chronic administration of selective serotonin reuptake inhibitors: a review of animal studies. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. vol 21. issue 1. 2019-04-26. PMID:30962407. |
gaba and glutamate genes also showed heterogeneous changes, with a surprising nmda receptor downregulation in areas including the striatum and amygdala, known to be involved in depressive states and stress reactions. |
2019-04-26 |
2023-08-13 |
Not clear |
| C Zussy, X Gómez-Santacana, X Rovira, D De Bundel, S Ferrazzo, D Bosch, D Asede, F Malhaire, F Acher, J Giraldo, E Valjent, I Ehrlich, F Ferraguti, J-P Pin, A Llebaria, C Goude. Dynamic modulation of inflammatory pain-related affective and sensory symptoms by optical control of amygdala metabotropic glutamate receptor 4. Molecular psychiatry. vol 23. issue 3. 2019-03-12. PMID:27994221. |
dynamic modulation of inflammatory pain-related affective and sensory symptoms by optical control of amygdala metabotropic glutamate receptor 4. |
2019-03-12 |
2023-08-13 |
Not clear |
| C Zussy, X Gómez-Santacana, X Rovira, D De Bundel, S Ferrazzo, D Bosch, D Asede, F Malhaire, F Acher, J Giraldo, E Valjent, I Ehrlich, F Ferraguti, J-P Pin, A Llebaria, C Goude. Dynamic modulation of inflammatory pain-related affective and sensory symptoms by optical control of amygdala metabotropic glutamate receptor 4. Molecular psychiatry. vol 23. issue 3. 2019-03-12. PMID:27994221. |
here, we show that activation of a specific intrinsic neuromodulatory system within the amygdala associated with type 4 metabotropic glutamate receptors (mglu |
2019-03-12 |
2023-08-13 |
Not clear |
| Song Lin, Xin Li, Yi-Hua Chen, Feng Gao, Hao Chen, Neng-Yuan Hu, Lang Huang, Zheng-Yi Luo, Ji-Hong Liu, Qiang-Long You, Ya-Nan Yin, Ze-Lin Li, Xiao-Wen Li, Zhuo-Jun Du, Jian-Ming Yang, Tian-Ming Ga. Social Isolation During Adolescence Induces Anxiety Behaviors and Enhances Firing Activity in BLA Pyramidal Neurons via mGluR5 Upregulation. Molecular neurobiology. vol 55. issue 6. 2019-02-04. PMID:28914419. |
strikingly, the mglur5 protein levels in the amygdala increased concomitantly with anxiety behaviors, and both intraperitoneal administration and intra-basolateral amygdala (bla) infusion of mpep, a metabotropic glutamate receptor 5 antagonist, normalized anxiety behaviors. |
2019-02-04 |
2023-08-13 |
mouse |
| Yukihiko Shirayama, Michio Takahashi, Fumio Osone, Akira Hara, Toshiyuki Okub. Myo-inositol, Glutamate, and Glutamine in the Prefrontal Cortex, Hippocampus, and Amygdala in Major Depression. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 2. issue 2. 2018-12-19. PMID:29560915. |
myo-inositol, glutamate, and glutamine in the prefrontal cortex, hippocampus, and amygdala in major depression. |
2018-12-19 |
2023-08-13 |
Not clear |
| Yukihiko Shirayama, Michio Takahashi, Fumio Osone, Akira Hara, Toshiyuki Okub. Myo-inositol, Glutamate, and Glutamine in the Prefrontal Cortex, Hippocampus, and Amygdala in Major Depression. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 2. issue 2. 2018-12-19. PMID:29560915. |
our a priori hypothesis was that myo-inositol and glutamate were downregulated in the hippocampus and amygdala in depression. |
2018-12-19 |
2023-08-13 |
Not clear |
| Adam Hamed, Miron Bartosz Kurs. Inter-individual differences in serotonin and glutamate co-transmission reflect differentiation in context-induced conditioned 50-kHz USVs response after morphine withdrawal. Brain structure & function. vol 223. issue 7. 2018-12-11. PMID:29774428. |
moreover, 5-ht concentration in amygdala is bound up with glutamate level in this structure as well as in hippocampus. |
2018-12-11 |
2023-08-13 |
rat |
| Sara Poletti, Martina Riberto, Benedetta Vai, Davide Ghiglino, Cristina Lorenzi, Alice Vitali, Silvia Brioschi, Clara Locatelli, Alessandro Serretti, Cristina Colombo, Francesco Benedett. A Glutamate Transporter EAAT1 Gene Variant Influences Amygdala Functional Connectivity in Bipolar Disorder. Journal of molecular neuroscience : MN. vol 65. issue 4. 2018-11-08. PMID:30073554. |
a glutamate transporter eaat1 gene variant influences amygdala functional connectivity in bipolar disorder. |
2018-11-08 |
2023-08-13 |
human |