| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ángeles Prados-Pardo, Elena Martín-González, Santiago Mora, Carlos Martín, Manuela Olmedo-Córdoba, Cristian Pérez-Fernandez, Fernando Sánchez-Santed, Margarita Moreno-Montoy. Reduced Expression of the Htr2a, Grin1, and Bdnf Genes and Cognitive Inflexibility in a Model of High Compulsive Rats. Molecular neurobiology. 2023-07-31. PMID:37523044. |
the possible underlying mechanisms might be linked to the brain gene expression of 5ht2a, 5ht2c, glutamate nmda receptors, and brain-derived neurotrophic factor (bdnf) in fc, hippocampus, and amygdala. |
2023-07-31 |
2023-08-14 |
rat |
| Eric T Winzenried, Anna C Everett, Erin R Saito, Roxanne M Miller, Taylor Johnson, Eliza Neal, Zachary Boyce, Calvin Smith, Chloe Jensen, Spencer Kimball, Adam Brantley, Gabriel Melendez, Devin Moffat, Erin Davis, Lyndsey Aponik, Tyler Crofts, Bryson Dabney, Jeffrey G Edward. Effects of a True Prophylactic Treatment on Hippocampal and Amygdala Synaptic Plasticity and Gene Expression in a Rodent Chronic Stress Model of Social Defeat. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37446371. |
using competitive elisas on plasma, field electrophysiology at ca1 of the ventral hippocampus (vh) and the basolateral amygdala (bla), quantitative rt-pcr, and behavior assays, we demonstrate that our sd stress increased anxiety-like behavior, elevated long-term potentiation (ltp) in the vh and bla, and altered the expression of mineralocorticoid, glucocorticoid, and glutamate receptors. |
2023-07-14 |
2023-08-14 |
rat |
| Nina Colombel, Guillaume Ferreira, Regina M Sullivan, Gérard Coureau. Dynamic developmental changes in neurotransmitters supporting infant attachment learning. Neuroscience and biobehavioral reviews. 2023-05-31. PMID:37257712. |
here we review the neural circuitry supporting this neonatal odor learning, unique compared to adults, focusing specifically on the early roles of neurotransmitters such as glutamate, gaba (gamma-aminobutyric acid), serotonin, dopamine and norepinephrine, in the olfactory bulb, the anterior piriform cortex and amygdala. |
2023-05-31 |
2023-08-14 |
Not clear |
| Saida Oubraim, Roh-Yu Shen, Samir Haj-Dahman. Oxytocin excites dorsal raphe serotonin neurons and bidirectionally gates their glutamate synapses. iScience. vol 26. issue 5. 2023-05-30. PMID:37250336. |
neuronal mapping demonstrates that oxt preferentially potentiates glutamate synapses of 5-ht neurons projecting to medial prefrontal cortex (mpfc) and depresses glutamatergic inputs to 5-ht neurons projecting to lateral habenula (lhb) and central amygdala (cea). |
2023-05-30 |
2023-08-14 |
Not clear |
| Alaa M Hammad, Ala A Alhusban, Lujain F Alzaghari, Fawaz Alasmari, Youssef Sar. Effect of Cigarette Smoke Exposure and Aspirin Treatment on Neurotransmitters' Tissue Content in Rats' Hippocampus and Amygdala. Metabolites. vol 13. issue 4. 2023-04-28. PMID:37110173. |
we examined the effects of cigarette smoke with and without aspirin treatment on the concentrations of neurotransmitters, including dopamine, serotonin, glutamate, glutamine, and gaba in the amygdala and hippocampus. |
2023-04-28 |
2023-08-14 |
rat |
| Alaa M Hammad, Ala A Alhusban, Lujain F Alzaghari, Fawaz Alasmari, Youssef Sar. Effect of Cigarette Smoke Exposure and Aspirin Treatment on Neurotransmitters' Tissue Content in Rats' Hippocampus and Amygdala. Metabolites. vol 13. issue 4. 2023-04-28. PMID:37110173. |
dopamine, serotonin, glutamate, glutamine, and gaba were extracted from both the amygdala and hippocampus and were separated and quantified using a developed and validated hplc-ms/ms method. |
2023-04-28 |
2023-08-14 |
rat |
| Lorraine Madur, Christian Ineichen, Giorgio Bergamini, Alexandra Greter, Giulia Poggi, Nagiua Cuomo-Haymour, Hannes Sigrist, Yaroslav Sych, Jean-Charles Paterna, Klaus D Bornemann, Coralie Viollet, Francesc Fernandez-Albert, Gregorio Alanis-Lobato, Bastian Hengerer, Christopher R Pryc. Stress deficits in reward behaviour are associated with and replicated by dysregulated amygdala-nucleus accumbens pathway function in mice. Communications biology. vol 6. issue 1. 2023-04-15. PMID:37061616. |
glutamate neurons in basal amygdala (ba) project to various regions including nucleus accumbens (nac). |
2023-04-15 |
2023-08-14 |
mouse |
| Saadet Inan, Joseph J Meissler, Aryan Shekarabi, Jeffrey Foss, Sonita Wiah, Toby K Eisenstein, Scott M Rawl. Cyanidin prevents MDPV withdrawal-induced anxiety-like effects and dysregulation of cytokine systems in rats. Brain research. 2023-03-05. PMID:36871847. |
during mdpv abstinence, mrna levels of glutamate aspartate transporter (glast) and glutamate transporter subtype 1 (glt-1) in the amygdala were also elevated but normalized by cyanidin treatment. |
2023-03-05 |
2023-08-14 |
rat |
| Claire M Corbett, Emily N D Miller, Jessica A Lowet. mGlu5 inhibition in the basolateral amygdala prevents estrous cycle-dependent changes in cue-induced cocaine seeking. Addiction neuroscience. vol 5. 2023-02-13. PMID:36778664. |
one region that contributes to both sex differences in behavioral responding and cue-induced cocaine seeking is the basolateral amygdala (bla), while one receptor known to play a critical role in mediating cocaine seeking behavior is metabotropic glutamate receptor 5 (mglu5). |
2023-02-13 |
2023-08-14 |
Not clear |
| Pawel Grochecki, Irena Smaga, Karolina Wydra, Marta Marszalek-Grabska, Tymoteusz Slowik, Ewa Kedzierska, Joanna Listos, Ewa Gibula-Tarlowska, Malgorzata Filip, Jolanta H Kotlinsk. Impact of Mephedrone on Fear Memory in Adolescent Rats: Involvement of Matrix Metalloproteinase-9 (MMP-9) and N-Methyl-D-aspartate (NMDA) Receptor. International journal of molecular sciences. vol 24. issue 3. 2023-02-11. PMID:36768263. |
we also analyzed whether these trauma-induced changes were associated with exacerbation in metalloproteinase-9 (mmp-9) and the glun2a and glun2b subunits of n-methyl-d-aspartate (nmda) glutamate receptor expression in such brain structures as the hippocampus and basolateral amygdala. |
2023-02-11 |
2023-08-14 |
rat |
| Stefania Dimonte, Vladyslav Sikora, Maria Bove, Maria Grazia Morgese, Paolo Tucci, Stefania Schiavone, Luigia Trabac. Social isolation from early life induces anxiety-like behaviors in adult rats: Relation to neuroendocrine and neurochemical dysfunctions. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 158. 2023-01-02. PMID:36592494. |
social isolation also caused a reduction of noradrenaline, serotonin and gaba levels, together with an increase of serotonin turnover and glutamate levels in the amygdala of isolated animals. |
2023-01-02 |
2023-08-14 |
human |
| Laura C Ornelas, Giorgia Boero, Kalynn Van Voorhies, Todd K O'Buckley, Joyce Besheer, A Leslie Morro. Pharmacological administration of 3α,5α-THP into nucleus accumbens core increases 3α,5α-THP expression and reduces alcohol self-administration. Alcoholism, clinical and experimental research. 2023-01-01. PMID:36587947. |
alcohol affects multiple circuits in the brain, mainly disrupting the delicate balance between inhibitory γ-aminobutyric acid (gaba) transmission and excitatory glutamate signaling in brain areas involved in reward circuits, such as amygdala, nucleus accumbens (acb) and ventral tegmental area (vta), causing loss of control in circuits that regulate behavioral control of craving, alcohol-seeking and intake. |
2023-01-01 |
2023-08-14 |
human |
| Vanessa Pereira, Juri Aparicio Arias, Amadeu Llebaria, Cyril Goude. Photopharmacological manipulation of amygdala metabotropic glutamate receptor mGlu4 alleviates neuropathic pain. Pharmacological research. 2022-12-18. PMID:36529205. |
photopharmacological manipulation of amygdala metabotropic glutamate receptor mglu4 alleviates neuropathic pain. |
2022-12-18 |
2023-08-14 |
Not clear |
| Deyana Ivanova, Xiao-Feng Li, Caitlin McIntyre, Kevin T O'Byrn. Posterodorsal medial amygdala urocortin-3, GABA and glutamate mediate suppression of LH pulsatility in female mice. Endocrinology. 2022-11-29. PMID:36445688. |
posterodorsal medial amygdala urocortin-3, gaba and glutamate mediate suppression of lh pulsatility in female mice. |
2022-11-29 |
2023-08-14 |
mouse |
| Jianlong Ge, Youqing Cai, Zhizhong Z Pa. Synaptic plasticity in two cell types of central amygdala for regulation of emotion and pain. Frontiers in cellular neuroscience. vol 16. 2022-11-17. PMID:36385947. |
we found that 50% of the cell population in the lateral division of the central nucleus of the amygdala (ceal) received glutamate inputs from both basolateral amygdala (bla) and from the parabrachial nucleus (pbn), and 39% of the remaining ceal cells received glutamate inputs only from pbn. |
2022-11-17 |
2023-08-14 |
rat |
| Niklas Reich, Christian Hölsche. Beyond Appetite: Acylated Ghrelin As A Learning, Memory and Fear Behavior-modulating Hormone. Neuroscience and biobehavioral reviews. 2022-11-11. PMID:36368526. |
as such, in this review, we i) evaluate what specific stages and forms of memory, as well as which respective brain areas are affected by acylated ghrelin, ii) illustrate the plasticity-associated signaling pathways of ag in the hippocampus, also involving memory resolution-enhancing neurogenesis, iii) elucidate how the peptide modulates neurotransmitter systems (glutamate, γ-aminobutyric acid, dopamine, serotonin), iv) clarify the role of ag in conditioned taste aversion, novelty learning and the formation of spatial, recognition, auditory fear, contextual fear and passive avoidance memories in the hippocampus and amygdala as well as v) solve the mystery behind ag, its impact on the 5-ht system, the recently established link to post-traumatic stress disorder and the either fear-suppressing or fear-potentiating effects under neutral and acutely stressed conditions or chronic stress, respectively. |
2022-11-11 |
2023-08-14 |
Not clear |
| Oluwarotimi O Folorunso, Theresa L Harvey, Stephanie E Brown, Gabriele Chelini, Sabina Berretta, Darrick T Bal. The D-serine biosynthetic enzyme serine racemase is expressed by reactive astrocytes in the amygdala of human and a mouse model of Alzheimer's disease. Neuroscience letters. 2022-11-10. PMID:36356820. |
our results suggest that d-serine produced by reactive astrocytes in the amygdala could contribute to glutamate excitotoxicity and neurodegeneration observed with ad progression. |
2022-11-10 |
2023-08-14 |
mouse |
| Irina Adamcyzk, Diana Kúkeľová, Stefan Just, Ricardo Giovannini, Hannes Sigrist, Rene Amport, Nagiua Cuomo-Haymour, Giulia Poggi, Christopher R Pryc. Somatostatin Receptor 4 Agonism Normalizes Stress-Related Excessive Amygdala Glutamate Release and Pavlovian Aversion Learning and Memory in Rodents. Biological psychiatry global open science. vol 2. issue 4. 2022-11-03. PMID:36324659. |
somatostatin receptor 4 agonism normalizes stress-related excessive amygdala glutamate release and pavlovian aversion learning and memory in rodents. |
2022-11-03 |
2023-08-14 |
Not clear |
| Geffen Lass, Xiao Feng Li, Margaritis Voliotis, Ellen Wall, Ross A de Burgh, Deyana Ivanova, Caitlin McIntyre, Xian-Hua Lin, William H Colledge, Stafford L Lightman, Krasimira Tsaneva-Atanasova, Kevin T O'Byrn. GnRH pulse generator frequency is modulated by kisspeptin and GABA-glutamate interactions in the posterodorsal medial amygdala in female mice. Journal of neuroendocrinology. 2022-10-28. PMID:36305576. |
we have shown experimentally and verified using a mathematical model that functional neurotransmission of both gaba and glutamate is a requirement for effective modulation of the gnrh pulse generator by amygdala kisspeptin neurons. |
2022-10-28 |
2023-08-14 |
mouse |
| Megan L Bertholomey, Vidhya Nagarajan, Dana M Smith, Mary M Torregross. Sex- and age-dependent effects of chronic corticosterone exposure on depressive-like, anxiety-like, and fear-related behavior: Role of amygdala glutamate receptors in the rat. Frontiers in behavioral neuroscience. vol 16. 2022-10-10. PMID:36212195. |
sex- and age-dependent effects of chronic corticosterone exposure on depressive-like, anxiety-like, and fear-related behavior: role of amygdala glutamate receptors in the rat. |
2022-10-10 |
2023-08-14 |
rat |