| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicholas J Brandon, Jasmina N Jovanovic, Trevor G Smart, Stephen J Mos. Receptor for activated C kinase-1 facilitates protein kinase C-dependent phosphorylation and functional modulation of GABA(A) receptors with the activation of G-protein-coupled receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 15. 2002-09-03. PMID:12151513. |
these receptors are hetero-pentamers that can be assembled from a number of subunit classes: alpha(1-6), beta(1-3), gamma(1-3), delta(1), epsilon, theta;, and pi, but the majority of receptor subtypes is believed, however, to be composed of alpha, beta, and gamma2 subunits. |
2002-09-03 |
2023-08-12 |
Not clear |
| J Moraczewski, A Nowotniak, E Wróbel, M Castagna, J Gautron, I Martell. Differential changes in protein kinase C associated with regeneration of rat extensor digitorum longus and soleus muscles. The international journal of biochemistry & cell biology. vol 34. issue 8. 2002-08-30. PMID:12007632. |
pkc theta; being present the earliest, then delta, epsilon and alpha and finally zeta, beta and eta. |
2002-08-30 |
2023-08-12 |
rat |
| Tony T Huang, Shelby L Feinberg, Sainath Suryanarayanan, Shigeki Miyamot. The zinc finger domain of NEMO is selectively required for NF-kappa B activation by UV radiation and topoisomerase inhibitors. Molecular and cellular biology. vol 22. issue 16. 2002-08-30. PMID:12138192. |
the phospho-i kappa b alpha generated by uv is only detectable by expressing a delta f-box mutant of the ubiquitin ligase beta-trcp, which serves as a specific substrate trap for serine 32 and 36 phosphorylated i kappa b alpha. |
2002-08-30 |
2023-08-12 |
Not clear |
| Inger Sundstrom-Poromaa, Deborah H Smith, Qi Hua Gong, Thomas N Sabado, Xinshe Li, Adam Light, Martin Wiedmann, Keith Williams, Sheryl S Smit. Hormonally regulated alpha(4)beta(2)delta GABA(A) receptors are a target for alcohol. Nature neuroscience. vol 5. issue 8. 2002-08-29. PMID:12118257. |
hormonally regulated alpha(4)beta(2)delta gaba(a) receptors are a target for alcohol. |
2002-08-29 |
2023-08-12 |
rat |
| Inger Sundstrom-Poromaa, Deborah H Smith, Qi Hua Gong, Thomas N Sabado, Xinshe Li, Adam Light, Martin Wiedmann, Keith Williams, Sheryl S Smit. Hormonally regulated alpha(4)beta(2)delta GABA(A) receptors are a target for alcohol. Nature neuroscience. vol 5. issue 8. 2002-08-29. PMID:12118257. |
here we report that low concentrations of alcohol (1-3 mm) increased cl(-) currents gated by a recombinant gaba(a) receptor, alpha(4)beta(2)delta, by 40-50% in xenopus laevis oocytes. |
2002-08-29 |
2023-08-12 |
rat |
| Inger Sundstrom-Poromaa, Deborah H Smith, Qi Hua Gong, Thomas N Sabado, Xinshe Li, Adam Light, Martin Wiedmann, Keith Williams, Sheryl S Smit. Hormonally regulated alpha(4)beta(2)delta GABA(A) receptors are a target for alcohol. Nature neuroscience. vol 5. issue 8. 2002-08-29. PMID:12118257. |
we also found greater hippocampal expression of receptors containing alpha(4) and delta subunits, using a rat model of premenstrual syndrome (pms) in which 1-3 mm alcohol preferentially enhanced gaba-gated currents, and low doses of alcohol attenuated anxiety and behavioral reactivity. |
2002-08-29 |
2023-08-12 |
rat |
| Sandra M Hayes, Paul E Lov. Distinct structure and signaling potential of the gamma delta TCR complex. Immunity. vol 16. issue 6. 2002-08-29. PMID:12121664. |
alpha beta and gamma delta t cells are distinguished by the clonotypic subunits contained within their tcrs. |
2002-08-29 |
2023-08-12 |
Not clear |
| Sandra M Hayes, Paul E Lov. Distinct structure and signaling potential of the gamma delta TCR complex. Immunity. vol 16. issue 6. 2002-08-29. PMID:12121664. |
although the alpha beta tcr has been well characterized, much less is known about the gamma delta tcr. |
2002-08-29 |
2023-08-12 |
Not clear |
| Sandra M Hayes, Paul E Lov. Distinct structure and signaling potential of the gamma delta TCR complex. Immunity. vol 16. issue 6. 2002-08-29. PMID:12121664. |
here, we report that, unlike alpha beta t crs, most gamma delta tcrs expressed on ex vivo gamma delta t cells lack cd3 delta. |
2002-08-29 |
2023-08-12 |
Not clear |
| Sandra M Hayes, Paul E Lov. Distinct structure and signaling potential of the gamma delta TCR complex. Immunity. vol 16. issue 6. 2002-08-29. PMID:12121664. |
despite this structural difference, signal transduction by the gamma delta tcr is superior to that of the alpha beta tcr, as measured by its ability to induce calcium mobilization, erk activation, and cellular proliferation. |
2002-08-29 |
2023-08-12 |
Not clear |
| Sandra M Hayes, Paul E Lov. Distinct structure and signaling potential of the gamma delta TCR complex. Immunity. vol 16. issue 6. 2002-08-29. PMID:12121664. |
these results reveal fundamental differences in the primary structure and signaling potential of the alpha beta- and gamma delta tcr complexes. |
2002-08-29 |
2023-08-12 |
Not clear |
| Anita Wolfer, Anne Wilson, Mohamed Nemir, H Robson MacDonald, Freddy Radtk. Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes. Immunity. vol 16. issue 6. 2002-08-29. PMID:12121668. |
here, we demonstrate that loss of notch1 signaling at an earlier (cd44(+)cd25(+)) developmental stage results in severe perturbation of alpha beta but not gamma delta lineage development. |
2002-08-29 |
2023-08-12 |
Not clear |
| Jamila Ismaili, Véronique Olislagers, Rémy Poupot, Jean-Jacques Fournié, Michel Goldma. Human gamma delta T cells induce dendritic cell maturation. Clinical immunology (Orlando, Fla.). vol 103. issue 3 Pt 1. 2002-08-28. PMID:12173304. |
we conclude that gamma delta t cell activation might result in dc maturation and thereby in enhanced alpha beta t cell responses. |
2002-08-28 |
2023-08-12 |
human |
| Piotr P Murzenok, Darius Matusevicius, Mark S Freedma. gamma/delta T cells in multiple sclerosis: chemokine and chemokine receptor expression. Clinical immunology (Orlando, Fla.). vol 103. issue 3 Pt 1. 2002-08-28. PMID:12173306. |
we observed higher rantes production by ms gamma delta than by alpha beta t cell lines. |
2002-08-28 |
2023-08-12 |
Not clear |
| Piotr P Murzenok, Darius Matusevicius, Mark S Freedma. gamma/delta T cells in multiple sclerosis: chemokine and chemokine receptor expression. Clinical immunology (Orlando, Fla.). vol 103. issue 3 Pt 1. 2002-08-28. PMID:12173306. |
most of the ms as well as the hc gamma delta and alpha beta t cell lines expressed cxcr3, while expression of cxcr1 was low. |
2002-08-28 |
2023-08-12 |
Not clear |
| Hiroshi Yoshimura, Tokio Sugai, Norihiko Onoda, Natsuki Segami, Nobuo Kat. Age-dependent occurrence of synchronized population oscillation suggestive of a developing functional coupling between NMDA and ryanodine receptors in the neocortex. Brain research. Developmental brain research. vol 136. issue 1. 2002-08-27. PMID:12036518. |
synchronized population oscillation of delta to alpha range frequencies was synaptically induced in rat visual cortex neurons, depending on (1) the extent of n-methyl-d-aspartate (nmda) receptor activation, (2) occurrence of calcium-induced calcium release (cicr), and (3) the age of animals. |
2002-08-27 |
2023-08-12 |
rat |
| Jung W Choi, Christine Pampeno, Stanislav Vukmanovic, Daniel Meruel. Characterization of the transcriptional expression of Notch-1 signaling pathway members, Deltex and HES-1, in developing mouse thymocytes. Developmental and comparative immunology. vol 26. issue 6. 2002-08-15. PMID:12031417. |
targeted thymocyte expression of the notch-1 intracellular domain has been shown to affect lineage commitment decisions such as those involving t cell vs. b cell, thymocyte alpha beta vs. gamma delta tcr, as well as cd4 vs. cd8 thymocyte commitment. |
2002-08-15 |
2023-08-12 |
mouse |
| Jennifer Wu, Veronika Groh, Thomas Spie. T cell antigen receptor engagement and specificity in the recognition of stress-inducible MHC class I-related chains by human epithelial gamma delta T cells. Journal of immunology (Baltimore, Md. : 1950). vol 169. issue 3. 2002-08-13. PMID:12133944. |
mic function as ligands for nkg2d-dap10, an activating receptor complex that triggers nk cells, costimulates cd8 alpha beta and v(gamma)9v(delta)2 gamma delta t cells, and is required for stimulation of v(delta)1 gamma delta t cells. |
2002-08-13 |
2023-08-12 |
human |
| Matthias Paul, Ralf M Fokt, Christoph H Kindler, Natalie C J Dipp, C Spencer Yos. Characterization of the interactions between volatile anesthetics and neuromuscular blockers at the muscle nicotinic acetylcholine receptor. Anesthesia and analgesia. vol 95. issue 2. 2002-08-13. PMID:12145052. |
the adult mouse muscle nicotinic acetylcholine receptor (alpha(2), beta, delta, epsilon) was heterologously expressed in xenopus laevis oocytes. |
2002-08-13 |
2023-08-12 |
mouse |
| John Winer, Sharon Hughes, Joanne Cooper, Anne Ben-Smith, Caroline Savag. gamma delta T cells infiltrating sensory nerve biopsies from patients with inflammatory neuropathy. Journal of neurology. vol 249. issue 5. 2002-08-09. PMID:12021953. |
in order to establish whether gamma delta t cells were present in these infiltrates we examined the expression of alpha beta and gamma delta t cell receptors in the biopsy specimens from patients with inflammatory neuropathy. |
2002-08-09 |
2023-08-12 |
Not clear |