| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bo-Hye Nam, Ikuo Hirono, Takashi Aok. The four TCR genes of teleost fish: the cDNA and genomic DNA analysis of Japanese flounder (Paralichthys olivaceus) TCR alpha-, beta-, gamma-, and delta-chains. Journal of immunology (Baltimore, Md. : 1950). vol 170. issue 6. 2003-06-25. PMID:12626564. |
the c delta 1 gene consists of two exons, one that encodes an extracellular ig-like domain (exon 1) and the other that encodes either a very short or possibly a lacking cp region, a transmembrane region, and a cytoplasmic tail (exon 2); these are located within tcr alpha gene locus. |
2003-06-25 |
2023-08-12 |
Not clear |
| Cristina M Tato, Alejandro Villarino, Jorge H Caamaño, Mark Boothby, Christopher A Hunte. Inhibition of NF-kappa B activity in T and NK cells results in defective effector cell expansion and production of IFN-gamma required for resistance to Toxoplasma gondii. Journal of immunology (Baltimore, Md. : 1950). vol 170. issue 6. 2003-06-25. PMID:12626571. |
i kappa b alpha(delta n)-transgenic (tg) mice succumbed to t. gondii infection between days 12 and 35, and death was associated with an increased parasite burden compared with wild-type (wt) controls. |
2003-06-25 |
2023-08-12 |
mouse |
| Jen-Kun Cheng, Yu-Jun Lai, Chien-Chuan Chen, Ching-Rong Cheng, Lih-Chu Chio. Magnesium chloride and ruthenium red attenuate the antiallodynic effect of intrathecal gabapentin in a rat model of postoperative pain. Anesthesiology. vol 98. issue 6. 2003-06-24. PMID:12766660. |
an endogenous binding site of [3h]gabapentin has been revealed to be the alpha(2)delta subunit of voltage-dependent ca2+ channels. |
2003-06-24 |
2023-08-12 |
rat |
| Christelle Perrault, Pierre Mangin, Martine Santer, Marie-Jeanne Baas, Sylvie Moog, Susan L Cranmer, Inna Pikovski, David Williamson, Shaun P Jackson, Jean-Pierre Cazenave, François Lanz. Role of the intracellular domains of GPIb in controlling the adhesive properties of the platelet GPIb/V/IX complex. Blood. vol 101. issue 9. 2003-06-20. PMID:12522011. |
a role of the gpib alpha intracellular domain was also apparent as the vwf-dependent adhesion of cells containing deletions of the entire (delta 518-610) or portions (delta 535-568, delta 569-610) of the gpib alpha cytoplasmic tail was insensitive to ram.1 inhibition. |
2003-06-20 |
2023-08-12 |
Not clear |
| Christelle Perrault, Pierre Mangin, Martine Santer, Marie-Jeanne Baas, Sylvie Moog, Susan L Cranmer, Inna Pikovski, David Williamson, Shaun P Jackson, Jean-Pierre Cazenave, François Lanz. Role of the intracellular domains of GPIb in controlling the adhesive properties of the platelet GPIb/V/IX complex. Blood. vol 101. issue 9. 2003-06-20. PMID:12522011. |
cells carrying progressive 11 amino acid deletions spanning the gpib alpha 535-590 region were equally unresponsive to ram.1, with the exception of those containing gpib alpha delta 569-579, which behaved like control cells. |
2003-06-20 |
2023-08-12 |
Not clear |
| Jorge R Toro, David J Liewehr, Nina Pabby, Lynn Sorbara, Mark Raffeld, Seth M Steinberg, Elaine S Jaff. Gamma-delta T-cell phenotype is associated with significantly decreased survival in cutaneous T-cell lymphoma. Blood. vol 101. issue 9. 2003-06-20. PMID:12522013. |
the importance of alpha beta versus gamma delta t-cell subset antigen expression in the classification of peripheral t-cell lymphomas is still unclear. |
2003-06-20 |
2023-08-12 |
Not clear |
| Jorge R Toro, David J Liewehr, Nina Pabby, Lynn Sorbara, Mark Raffeld, Seth M Steinberg, Elaine S Jaff. Gamma-delta T-cell phenotype is associated with significantly decreased survival in cutaneous T-cell lymphoma. Blood. vol 101. issue 9. 2003-06-20. PMID:12522013. |
univariate analysis indicated that there was a statistically significant difference in survival between the patients with alpha beta cutaneous t-cell lymphoma and patients with gamma delta cutaneous t-cell lymphoma (p <.0001). |
2003-06-20 |
2023-08-12 |
Not clear |
| Jhimli Dasgupta, Udayaditya Sen, Debi Choudhury, Poppy Datta, Abhijit Chakrabarti, Sudipa Basu Chakrabarty, Amit Chakrabarty, J K Dattagupt. Crystallization and preliminary X-ray structural studies of hemoglobin A2 and hemoglobin E, isolated from the blood samples of beta-thalassemic patients. Biochemical and biophysical research communications. vol 303. issue 2. 2003-06-20. PMID:12659864. |
hemoglobin a(2) (alpha(2)delta(2)), a minor (2-3%) component of circulating red blood cells, acts as an anti-sickling agent and its elevated concentration in beta-thalassemia is a useful clinical diagnostic. |
2003-06-20 |
2023-08-12 |
Not clear |
| M Omar Faison, Ed F Perozzi, Nicole Caran, Jennifer K Stewart, Robert M Tombe. Axonal localization of delta Ca2+/calmodulin-dependent protein kinase II in developing P19 neurons. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 20. issue 8. 2003-06-17. PMID:12526889. |
delta camk-ii co-localizes with the axonal protein gap-43, but not the dendritic microtubule-associated protein map-2, a known substrate of alpha camk-ii. |
2003-06-17 |
2023-08-12 |
mouse |
| Sinisa Urban, Daniel Schlieper, Matthew Freema. Conservation of intramembrane proteolytic activity and substrate specificity in prokaryotic and eukaryotic rhomboids. Current biology : CB. vol 12. issue 17. 2003-06-16. PMID:12225666. |
despite their striking sequence divergence, rhomboids from one gram-positive and four gram-negative species, including providencia, specifically cleaved drosophila substrates, but not similar proteins such as transforming growth factor alpha (tgfalpha) and delta. |
2003-06-16 |
2023-08-12 |
drosophila_melanogaster |
| S S Manna, Parongama Se. Modulated scale-free network in Euclidean space. Physical review. E, Statistical, nonlinear, and soft matter physics. vol 66. issue 6 Pt 2. 2003-06-16. PMID:12513354. |
the link length distribution follows a power law: d(l) approximately l(delta), where delta is calculated exactly for the whole range of values of alpha. |
2003-06-16 |
2023-08-12 |
Not clear |
| Joel E Wright, Gregory K Yurasek, Ying-Nan Chen, Andre Rosowsk. Further studies on the interaction of nonpolyglutamatable aminopterin analogs with dihydrofolate reductase and the reduced folate carrier as determinants of in vitro antitumor activity. Biochemical pharmacology. vol 65. issue 9. 2003-06-16. PMID:12732354. |
thirteen structural analogs of the potent nonpolyglutamatable dihydrofolate reductase inhibitor n(alpha)-(4-amino-4-deoxypteroyl)-n(delta)-hemiphthaloyl-l-ornithine (pt523) with modifications in the side chain, the para-aminobenzoyl moiety, or the 9,10-bridge were evaluated for the ability to inhibit human recombinant dihydrofolate reductase (dhfr), to utilize the reduced folate carrier (rfc) for influx, and to inhibit the growth of ccrf-cem human leukemia cells in culture. |
2003-06-16 |
2023-08-12 |
human |
| Bianca A Lauria-Horner, Robert B Poh. Pregabalin: a new anxiolytic. Expert opinion on investigational drugs. vol 12. issue 4. 2003-06-10. PMID:12665421. |
its main site of action appears to be on the alpha(2)delta subunit of voltage-dependent calcium channels, widely distributed throughout the peripheral and central nervous system. |
2003-06-10 |
2023-08-12 |
human |
| Elizabeth O Harrington, Jodi L Brunelle, Christopher J Shannon, Eric S Kim, Kirstin Mennella, Sharon Round. Role of protein kinase C isoforms in rat epididymal microvascular endothelial barrier function. American journal of respiratory cell and molecular biology. vol 28. issue 5. 2003-06-05. PMID:12707019. |
we investigated the role of protein kinase c (pkc) in monolayer permeability using endothelial cells (ec) overexpressing pkc alpha (pkc alpha ec), pkc delta (pkc delta ec) or vector (vector control ec) cdnas. |
2003-06-05 |
2023-08-12 |
rat |
| Elizabeth O Harrington, Jodi L Brunelle, Christopher J Shannon, Eric S Kim, Kirstin Mennella, Sharon Round. Role of protein kinase C isoforms in rat epididymal microvascular endothelial barrier function. American journal of respiratory cell and molecular biology. vol 28. issue 5. 2003-06-05. PMID:12707019. |
pkc inhibitors, gö6976 and rottlerin, reversed the effects of pkc alpha and pkc delta overexpression on permeability, respectively. |
2003-06-05 |
2023-08-12 |
rat |
| Elizabeth O Harrington, Jodi L Brunelle, Christopher J Shannon, Eric S Kim, Kirstin Mennella, Sharon Round. Role of protein kinase C isoforms in rat epididymal microvascular endothelial barrier function. American journal of respiratory cell and molecular biology. vol 28. issue 5. 2003-06-05. PMID:12707019. |
these findings demonstrate that monolayer permeability changes are differentially regulated by pkc isoenzymes, suggesting that pkc alpha promotes endothelial barrier dysfunction and pkc delta enhances basal endothelial barrier function. |
2003-06-05 |
2023-08-12 |
rat |
| Richard L Eckert, Tatiana Efimova, Sivaprakasam Balasubramanian, James F Crish, Frederic Bone, Shervin Dasht. p38 Mitogen-activated protein kinases on the body surface--a function for p38 delta. The Journal of investigative dermatology. vol 120. issue 5. 2003-06-05. PMID:12713588. |
the p38 family of mitogen-activated protein kinases includes p38 alpha (sapk2a, csbp), p38 beta (sapk2b), p38 delta (sapk4), and p38 gamma (sapk3/erk6). |
2003-06-05 |
2023-08-12 |
Not clear |
| Lee Chuan Yang, Dean C Ng, Daniel D Bikl. Role of protein kinase C alpha in calcium induced keratinocyte differentiation: defective regulation in squamous cell carcinoma. Journal of cellular physiology. vol 195. issue 2. 2003-05-30. PMID:12652652. |
in the normal keratinocytes, the levels of pkc [alpha], pkc [delta], pkc [eta], and pkc [zeta] increased over the first one to two weeks in a calcium-and time-dependent manner. |
2003-05-30 |
2023-08-12 |
human |
| Kota Arun Kumar, Yadavalli Rajgopal, Usha Pillai, Phanithi Prakash Bab. Activation of nuclear transcription factor-kappa B is associated with the induction of inhibitory kappa B kinase-beta and involves differential activation of protein kinase C and protein tyrosine kinases during fatal murine cerebral malaria. Neuroscience letters. vol 340. issue 2. 2003-05-29. PMID:12668256. |
in parallel, the levels of two pkc isoforms (alpha and delta) and tyrosine phosphorylated proteins were monitored to correlate the observed changes in the activity. |
2003-05-29 |
2023-08-12 |
mouse |
| M Swiatek, R E Regel, J Meurer, G Wanner, H B Pakrasi, I Ohad, R G Herrman. Effects of selective inactivation of individual genes for low-molecular-mass subunits on the assembly of photosystem II, as revealed by chloroplast transformation: the psbEFLJoperon in Nicotiana tabacum. Molecular genetics and genomics : MGG. vol 268. issue 6. 2003-05-23. PMID:12655396. |
disruption of psbeand psbf, which code for the alpha and beta apoproteins of cytochrome b(559), abolished psii activity, as expected; delta psbl and delta psbj plants displayed residual psii activity in young leaves. |
2003-05-23 |
2023-08-12 |
Not clear |