| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Gregory Ashby, Heidi A Zetzer, Collie W Conoley, Alan D Pickerin. Just do it: A neuropsychological theory of agency, cognition, mood, and dopamine. Journal of experimental psychology. General. vol 153. issue 6. 2024-06-17. PMID:38884963. |
a novel theory proposes that increases in agency disinhibit the dopamine system and thereby increase the number of tonically active dopamine neurons in the ventral tegmental area. |
2024-06-17 |
2024-06-19 |
human |
| Wan-Yu Zhao, Ji-You Tan. [Research Progress in the Correlation Between Dopamine and Clinical Characterization of Narcolepsy]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 46. issue 2. 2024-04-30. PMID:38686723. |
dopamine,a neurotransmitter ubiquitous in the body fluids,blood,and urine of mammals and humans,is responsible for regulating their functions and metabolism.the dopamine system is involved in the neurobiological mechanisms of narcolepsy in animals and humans.however,researchers have drawn different or even opposite conclusions when measuring the dopamine level in the cerebrospinal fluid of narcolepsy patients.studies have confirmed that the occurrence of narcolepsy is related to the irreversible loss of orexins.the autoimmune reaction caused by the interactions of environmental factors with genetic factors destroys the hypothalamic orexin neurons and reduces orexin secretion,thereby lowering the level of arousal.we introduce the research progress and current status of dopamine and clinical characterization of narcolepsy by reviewing more than 40 articles published from 1982 to 2023,aiming to provide a reference for studying the relationship between the dopamine level and clinical characterization of narcolepsy and searching for the biomarkers of type 2 narcolepsy. |
2024-04-30 |
2024-05-03 |
Not clear |
| Bo Söderpalm, Mia Ericso. Alcohol and the dopamine system. International review of neurobiology. vol 175. 2024-03-30. PMID:38555117. |
ethanol, like most addictive drugs, acutely activates the mesolimbic dopamine system and releases dopamine, and ethanol-associated stimuli also appear to trigger dopamine release. |
2024-03-30 |
2024-04-02 |
Not clear |
| Paige M Estave, Steven E Albertson, Anushree N Karkhanis, Sara R Jone. Co-targeting the kappa opioid receptor and dopamine transporter reduces motivation to self-administer cocaine and partially reverses dopamine system dysregulation. Scientific reports. vol 14. issue 1. 2024-03-19. PMID:38499566. |
co-targeting the kappa opioid receptor and dopamine transporter reduces motivation to self-administer cocaine and partially reverses dopamine system dysregulation. |
2024-03-19 |
2024-03-21 |
rat |
| Patrick R Melugin, Suzanne O Nolan, Evelyn Kandov, Carson F Ferrara, Zahra Z Farahbakhsh, Cody A Sicilian. Medial prefrontal dopamine dynamics reflect allocation of selective attention. bioRxiv : the preprint server for biology. 2024-03-18. PMID:38496533. |
the mesocortical dopamine system is comprised of midbrain dopamine neurons that predominantly innervate the medial prefrontal cortex (mpfc) and exert a powerful neuromodulatory influence over this region |
2024-03-18 |
2024-03-20 |
Not clear |
| Jillian L Seiler, Xiaowen Zhuang, Alexandra B Nelson, Talia N Lerne. Dopamine across timescales and cell types: Relevance for phenotypes in Parkinson's disease progression. Experimental neurology. 2024-01-19. PMID:38242300. |
here, we review recent conceptual advances in our basic understanding of the dopamine system - including our rapidly advancing knowledge of dopamine neuron heterogeneity - with special attention to their importance for understanding pd. |
2024-01-19 |
2024-01-22 |
Not clear |
| Pengyu Zeng, Tiantian Wang, Lisan Zhang, Fang Gu. Exploring the causes of augmentation in restless legs syndrome. Frontiers in neurology. vol 14. 2023-10-16. PMID:37840917. |
dysfunction of the dopamine system highly possibly plays a role in the development of rls augmentation, as dopamine agonists improve desensitization of dopamine receptors, disturb receptor interactions within or outside the dopamine receptor family, and interfere with the natural regulation of dopamine synthesis and release in the neural system. |
2023-10-16 |
2023-11-08 |
Not clear |
| Anthony A Grace, Daniela L Ulian. Insights into the Mechanism of Action of Antipsychotic Drugs Derived from Animal Models: Standard of Care versus Novel Targets. International journal of molecular sciences. vol 24. issue 15. 2023-08-12. PMID:37569748. |
therapeutic intervention for schizophrenia relies on blockade of dopamine d2 receptors in the associative striatum; however, there is little evidence for baseline overdrive of the dopamine system. |
2023-08-12 |
2023-08-16 |
Not clear |
| Deepika Suri, Giulia Zanni, Darshini Mahadevia, Nao Chuhma, Rinki Saha, Stephen Spivack, Nicolò Pini, Gregory S Stevens, Annette Ziolkowski-Blake, Eleanor H Simpson, Peter Balsam, Stephen Rayport, Mark S Ansorg. Dopamine transporter blockade during adolescence increases adult dopamine function, impulsivity, and aggression. Molecular psychiatry. 2023-08-02. PMID:37532798. |
the dopamine system is pivotal in controlling and shaping adolescent behaviors, and it undergoes heightened plasticity during that time, such that interference with dopamine signaling can have long-lasting behavioral consequences. |
2023-08-02 |
2023-08-14 |
mouse |
| Dillon J McGovern, Abigail M Polter, Emily D Prévost, Annie Ly, Connor J McNulty, Bodhi Rubinstein, David H Roo. Ventral tegmental area glutamate neurons establish a mu-opioid receptor gated circuit to mesolimbic dopamine neurons and regulate opioid-seeking behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-07-05. PMID:37407648. |
this vta glutamate to vta dopamine pathway regulated dopamine release to the nucleus accumbens through mu-opioid receptor activity in vivo. |
2023-07-05 |
2023-08-14 |
mouse |
| Sam Z Bacharach, David A Martin, Cassie A Stapf, Fangmiao Sun, Yulong Li, Joseph F Cheer, Donna J Cal. Decreased ventral tegmental area CB1R signaling reduces sign-tracking and shifts cue-outcome dynamics in rat nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-05-19. PMID:37208179. |
here, we examine a critical regulator of the dopamine system; endocannabinoids, which bind the cannabinoid receptor-1 (cb1r) in the ventral tegmental area (vta) to control cue-evoked striatal dopamine levels. |
2023-05-19 |
2023-08-14 |
rat |
| Paige M Estave, Haiguo Sun, Emily G Peck, Katherine M Holleran, Rong Chen, Sara R Jone. Cocaine self-administration augments kappa opioid receptor system-mediated inhibition of dopamine activity in the mesolimbic dopamine system. IBRO neuroscience reports. vol 14. 2023-02-07. PMID:36748012. |
cocaine self-administration augments kappa opioid receptor system-mediated inhibition of dopamine activity in the mesolimbic dopamine system. |
2023-02-07 |
2023-08-14 |
human |
| Jörgen A Engel, Erik Pålsson, Daniel Vallöf, Elisabet Jerlha. Ghrelin activates the mesolimbic dopamine system via nitric oxide associated mechanisms in the ventral tegmental area. Nitric oxide : biology and chemistry. 2022-12-13. PMID:36513266. |
besides enhanced feeding, the orexigenic peptide ghrelin activates the mesolimbic dopamine system to cause reward as measured by locomotor stimulation, dopamine release in nucleus accumbens shell (nacs), and conditioned place preference. |
2022-12-13 |
2023-08-14 |
Not clear |
| Xiaojie Liu, Casey R Vickstrom, Hao Yu, Shuai Liu, Shana Terai Snarrenberg, Vladislav Friedman, Lianwei Mu, Bixuan Chen, Thomas J Kelly, David A Baker, Qing-Song Li. Epac2 in midbrain dopamine neurons contributes to cocaine reinforcement via facilitation of dopamine release. eLife. vol 11. 2022-08-22. PMID:35993549. |
here, we report that epac2 in the mesolimbic dopamine system promotes cocaine reinforcement via enhancement of dopamine release. |
2022-08-22 |
2023-08-14 |
mouse |
| Seongtak Kang, Jeongrak Park, Yunho Jeong, Yong-Seok Oh, Ji-Woong Cho. Second-Derivative-Based Background Drift Removal for a Tonic Dopamine Measurement in Fast-Scan Cyclic Voltammetry. Analytical chemistry. 2022-08-08. PMID:35939536. |
although "tonic dopamine" (changes in minutes to hours) is critical for understanding the dopamine system, an electrochemical technique capable of simultaneously measuring phasic and tonic dopamine in an in vivo environment has not been established. |
2022-08-08 |
2023-08-14 |
Not clear |
| Kathryn L Todd, Janusz Lipski, Peter S Freeston. The Subthalamic Nucleus Exclusively Evokes Dopamine Release in the Tail of the Striatum. Journal of neurochemistry. 2022-07-23. PMID:35869680. |
our work identifies the stn as an important modulator of dopamine release in a novel dopamine pathway to the tail striatum, largely independent of the classic nigrostriatal pathway, which necessitates a revision of the basal ganglia circuitry with the stn positioned as a central integrator of striatal information. |
2022-07-23 |
2023-08-14 |
rat |
| Justin C Strickland, Cassandra D Gipson, Kelly E Dun. Dopamine Supersensitivity: A Novel Hypothesis of Opioid-Induced Neurobiological Mechanisms Underlying Opioid-Stimulant Co-use and Opioid Relapse. Frontiers in psychiatry. vol 13. 2022-05-02. PMID:35492733. |
synthesized conclusions of this body of research include evidence that changes in the dopamine system occur only once physical dependence to opioids develops, that the chronicity of opioid exposure is associated with the severity of changes, and that withdrawal leaves the organism in a state of substantive dopamine deficit that persists long after the somatic or observed signs of opioid withdrawal appear to have resolved. |
2022-05-02 |
2023-08-13 |
human |
| Kai-Chun Yang, Mu-N Liu, Bang-Hung Yang, Yuan-Hwa Cho. Role of dopamine transporter in the relationship between plasma cortisol and cognition. Psychosomatic medicine. 2022-04-26. PMID:35472074. |
regarding the effects of cortisol on the dopamine system and the association between dopamine transporter (dat) and cognition, dat might be a central target linking cortisol and cognition. |
2022-04-26 |
2023-08-13 |
Not clear |
| Semona Issa, Safa Chaabani, Alexandros G Asimakopoulos, Veerle L B Jaspers, Sigurd Einu. Maternal dopamine exposure provides offspring starvation resistance in Ecology and evolution. vol 12. issue 4. 2022-04-07. PMID:35386865. |
however, costs of expressing high dopamine levels remain poorly studied and are essential for understanding the evolution of the dopamine system. |
2022-04-07 |
2023-08-13 |
Not clear |
| Ameet S Nagpal, Daniel J Lodge, Jennifer S Potter, Alan Frazer, Robin Tragus, Megan E Curtis, Angela M Boley, Maxim Eckman. Analgesic Effects of Oxycodone in Combination With Risperidone or Ziprasidone: Results From a Pilot Randomized Controlled Trial in Healthy Volunteers. Frontiers in pain research (Lausanne, Switzerland). vol 3. 2022-03-17. PMID:35295795. |
given the role of the mesolimbic dopamine system in opioid reward, blocking dopamine d2 receptors should limit the abuse liability of opioid analgesics. |
2022-03-17 |
2023-08-13 |
human |