| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H B Rind, A F Russo, S R Whittemor. Developmental regulation of tryptophan hydroxylase messenger RNA expression and enzyme activity in the raphe and its target fields. Neuroscience. vol 101. issue 3. 2001-03-01. PMID:11113315. |
comparison of tryptophan hydroxylase messenger rna levels per cell and per brain section indicated a serotonergic loss between postnatal days 22 and 61 in both the dorsal raphe nucleus and nucleus raphe obscuris and may reflect either a loss of neurotransmitter phenotype or cell death. |
2001-03-01 |
2023-08-12 |
rat |
| P Boye. Do anxiety and depression have a common pathophysiological mechanism? Acta psychiatrica Scandinavica. Supplementum. issue 406. 2001-02-22. PMID:11131467. |
to review, examine and propose a common mechanism for anxiety and depression based on modifications observed in neurotransmitter systems (mainly noradrenergic and serotonergic) and dysregulation of the hypothalamic-pituitary-adrenal (hpa) axis. |
2001-02-22 |
2023-08-12 |
Not clear |
| K Koed, K Linne. Opposing changes in serotonin and norepinephrine transporter mRNA levels after serotonin depletion. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 6. 2001-02-08. PMID:11115741. |
we have now investigated the expression of both the 5htt and the norepinephrine transporter (net) gene to assess the possible interaction between the noradrenergic and the serotonergic neurotransmitter systems. |
2001-02-08 |
2023-08-12 |
Not clear |
| J F Quist, C L Barr, R Schachar, W Roberts, M Malone, R Tannock, V S Basile, J Beitchman, J L Kenned. Evidence for the serotonin HTR2A receptor gene as a susceptibility factor in attention deficit hyperactivity disorder (ADHD). Molecular psychiatry. vol 5. issue 5. 2001-02-01. PMID:11032388. |
the complex interaction between the serotonergic and dopaminergic neurotransmitter systems suggests that a balance between the two systems may be necessary for mediating hyperactive behaviour. |
2001-02-01 |
2023-08-12 |
mouse |
| J F Quist, C L Barr, R Schachar, W Roberts, M Malone, R Tannock, V S Basile, J Beitchman, J L Kenned. Evidence for the serotonin HTR2A receptor gene as a susceptibility factor in attention deficit hyperactivity disorder (ADHD). Molecular psychiatry. vol 5. issue 5. 2001-02-01. PMID:11032388. |
this may open a new door in adhd molecular genetics research, expanding the existing view of a catecholaminergic hypothesis to include a serotonergic hypothesis and should help elucidate the complex interplay among the neurotransmitter systems in the etiology of adhd. |
2001-02-01 |
2023-08-12 |
mouse |
| J M Rumsey, M Erns. Functional neuroimaging of autistic disorders. Mental retardation and developmental disabilities research reviews. vol 6. issue 3. 2000-10-16. PMID:10982494. |
neurotransmitter studies using positron emission tomography (pet) suggest abnormalities of serotonergic and dopaminergic function. |
2000-10-16 |
2023-08-12 |
human |
| J Wiltfang, W Nolte, J von Heppe, E Bahn, J Pilz, G Hajak, E Rüther, G Ramador. Sleep disorders and portal-systemic encephalopathy following transjugular intrahepatic portosystemic stent shunt in patients with liver cirrhosis. Relation to plasma tryptophan. Advances in experimental medicine and biology. vol 467. 2000-05-09. PMID:10721053. |
pse may be considered as a disorder of multiple neurotransmitter systems among which derangements of the serotonergic system have been documented most consistently. |
2000-05-09 |
2023-08-12 |
Not clear |
| S Mouillet-Richard, V Mutel, S Loric, C Tournois, J M Launay, O Kellerman. Regulation by neurotransmitter receptors of serotonergic or catecholaminergic neuronal cell differentiation. The Journal of biological chemistry. vol 275. issue 13. 2000-05-04. PMID:10734054. |
regulation by neurotransmitter receptors of serotonergic or catecholaminergic neuronal cell differentiation. |
2000-05-04 |
2023-08-12 |
Not clear |
| D J Nut. The psychobiology of posttraumatic stress disorder. The Journal of clinical psychiatry. vol 61 Suppl 5. 2000-04-21. PMID:10761676. |
data suggest that biological dysregulation of the glutamatergic, amine neurotransmitter (noradrenergic and serotonergic), and neuroendocrine pathways plays a fundamental part in the pathology of ptsd and may cause brain structural as well as functional abnormalities. |
2000-04-21 |
2023-08-12 |
Not clear |
| J Hennig, C Toll, P Schonlau, S Rohrmann, P Nette. Endocrine responses after d-fenfluramine and ipsapirone challenge: further support for Cloninger's tridimensional model of personality. Neuropsychobiology. vol 41. issue 1. 2000-03-21. PMID:10629434. |
the tridemensional model of personality introduced by cloninger relates aspects of novelty seeking to the dopaminergic, harm avoidance (ha) to the serotonergic, and reward dependence to the noradrenergic neurotransmitter system. |
2000-03-21 |
2023-08-12 |
human |
| J M Gorman, G Sulliva. Noradrenergic approaches to antidepressant therapy. The Journal of clinical psychiatry. vol 61 Suppl 1. 2000-03-09. PMID:10703758. |
although medications that target the serotonergic neurotransmitter system have recently dominated antidepressant therapy, atypical antidepressants--with either mixed serotonergic and noradrenergic effects or exclusively noradrenergic effects--have been shown to be clinically efficacious medications. |
2000-03-09 |
2023-08-12 |
Not clear |
| S E Marshall, T G Bird, K Hart, K I Wels. Unified approach to the analysis of genetic variation in serotonergic pathways. American journal of medical genetics. vol 88. issue 6. 2000-02-24. PMID:10581480. |
serotonin is a key neurotransmitter in the central nervous system, and dysregulation of serotonergic pathways has been implicated in the pathogenesis of many complex psychiatric diseases. |
2000-02-24 |
2023-08-12 |
Not clear |
| b' M Svetel, N Vojvodi\\xc4\\x87, S R Filipovi\\xc4\\x87, N Dragasevi\\xc4\\x87, N Sterni\\xc4\\x87, V S Kosti\\xc4\\x8. [Buspirone in the treatment of cerebellar ataxia]. Srpski arhiv za celokupno lekarstvo. vol 127. issue 9-10. 2000-02-10. PMID:10649900.' |
one possible approach could be a modification of potentially involved neurotransmitter systems of the cerebellum, where particularly interesting is the serotonergic system. |
2000-02-10 |
2023-08-12 |
Not clear |
| C M Portas, B Bjorvatn, R Ursi. Serotonin and the sleep/wake cycle: special emphasis on microdialysis studies. Progress in neurobiology. vol 60. issue 1. 2000-01-20. PMID:10622375. |
on the one hand serotonergic modulation on the sleep/wake cycle takes place through a multitude of post-synaptic receptors which mediate different or even opposite responses; on the other hand the achievement of a behavioral state depends on the complex interaction between the serotonergic and other neurotransmitter systems. |
2000-01-20 |
2023-08-12 |
Not clear |
| T Hendricks, N Francis, D Fyodorov, E S Deneri. The ETS domain factor Pet-1 is an early and precise marker of central serotonin neurons and interacts with a conserved element in serotonergic genes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 23. 1999-12-17. PMID:10575032. |
despite the widespread importance of the central serotonergic neurotransmitter system, little is known about the molecular mechanisms controlling the development of 5-ht neurons. |
1999-12-17 |
2023-08-12 |
mouse |
| E Reisner, M Nöldner, S Rossner, S S Chatterjee, V Bigl, R Schlieb. Acute effect of KA-672, a putative cognitive enhancer, on neurotransmitter receptor binding in mouse brain. Neuroscience letters. vol 274. issue 3. 1999-12-06. PMID:10548421. |
quantitative neurotransmitter receptor autoradiography was used as a tool to screen for ka-672-induced changes in a number of transmitter receptors including cholinergic, noradrenergic, glutamatergic, gabaergic, and serotonergic subtypes throughout the brain. |
1999-12-06 |
2023-08-12 |
mouse |
| R M Bagby, R D Levitan, S H Kennedy, A J Levitt, R T Joff. Selective alteration of personality in response to noradrenergic and serotonergic antidepressant medication in depressed sample: evidence of non-specificity. Psychiatry research. vol 86. issue 3. 1999-10-21. PMID:10482340. |
none of these studies, however, demonstrated a specific serotonergic effect on personality, as other neurotransmitter systems have not been assessed for their impact on these personality dimensions. |
1999-10-21 |
2023-08-12 |
Not clear |
| A Gasbarri, A Sulli, C Pacitti, J L McGaug. Serotonergic input to cholinergic neurons in the substantia innominata and nucleus basalis magnocellularis in the rat. Neuroscience. vol 91. issue 3. 1999-10-08. PMID:10391489. |
these findings show that serotonergic terminals, identified in very close association with the cholinergic neurons in the substantia innominata and nucleus basalis magnocellularis, derive primarily from the b7 serotonergic cell group of the dorsal raphe nucleus, and provide the neuroanatomical evidence for a direct functional interaction between these two neurotransmitter systems in the basal forebrain. |
1999-10-08 |
2023-08-12 |
rat |
| J Levenson, J H Byrne, A Eski. Levels of serotonin in the hemolymph of Aplysia are modulated by light/dark cycles and sensitization training. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 18. 1999-10-04. PMID:10479709. |
effects of injections of 5-ht and the morphology of the serotonergic system of aplysia indicate that 5-ht may have a humoral, in addition to a neurotransmitter, role. |
1999-10-04 |
2023-08-12 |
aplysia |
| S Rahman, T W Robbins, B J Sahakia. Comparative cognitive neuropsychological studies of frontal lobe function: implications for therapeutic strategies in frontal variant frontotemporal dementia. Dementia and geriatric cognitive disorders. vol 10 Suppl 1. 1999-10-01. PMID:10436335. |
finally, we evaluate critically the rationales for therapeutic modulation of noradrenergic, serotonergic and dopaminergic neurotransmitter systems at various stages of disease. |
1999-10-01 |
2023-08-12 |
Not clear |