| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Bengel, O Jöhren, A M Andrews, A Heils, R Mössner, G L Sanvitto, J M Saavedra, K P Lesch, D L Murph. Cellular localization and expression of the serotonin transporter in mouse brain. Brain research. vol 778. issue 2. 1998-03-03. PMID:9459551. |
the high-affinity serotonin (5-ht) transporter (5-htt) plays an important role in the removal of extracellular serotonin, thereby modulating and terminating the action of this neurotransmitter at various pre- and post-synaptic serotonergic receptors and heteroreceptors. |
1998-03-03 |
2023-08-12 |
mouse |
| R G Ruegg, J Gilmore, R D Ekstrom, M Corrigan, B Knight, M Tancer, M E Leatherman, S W Carson, R N Golde. Clomipramine challenge responses covary with Tridimensional Personality Questionnaire scores in healthy subjects. Biological psychiatry. vol 42. issue 12. 1998-02-10. PMID:9426882. |
cloninger's unified biosocial theory of personality postulates a relationship between the relative functional activity of central serotonergic, dopaminergic, and noradrenergic neurotransmitter systems, and the strength of three elemental dimensions of personality. |
1998-02-10 |
2023-08-12 |
human |
| A L Baum, S Misr. Selective serotonin-reuptake inhibitors in pregnancy and lactation. Harvard review of psychiatry. vol 4. issue 3. 1997-12-10. PMID:9384984. |
animal studies were inconclusive: some found that fetal exposure to high doses of fluoxetine produced no congenital anomalies, while others linked the drug to abnormalities such as craniofacial malformations, alterations in serotonergic neurotransmitter systems, birth-related hematomas, and inhibition of the milk-ejection reflex. |
1997-12-10 |
2023-08-12 |
human |
| J P Kelly, A S Wrynn, B E Leonar. The olfactory bulbectomized rat as a model of depression: an update. Pharmacology & therapeutics. vol 74. issue 3. 1997-11-25. PMID:9352586. |
alterations in the noradrenergic, serotonergic, cholinergic, gamma-aminobutyric acid (gaba)ergic and glutamatergic neurotransmitter systems are also associated with olfactory bulbectomy. |
1997-11-25 |
2023-08-12 |
rat |
| N K Dhingra, T R Raju, B L Met. Selective reduction of monoamine oxidase A and B in the frontal cortex of subordinate rats. Brain research. vol 758. issue 1-2. 1997-09-16. PMID:9203554. |
this finding may suggest a reduced neurotransmitter turnover in the serotonergic and dopaminergic neurons terminating in the frontal cortex. |
1997-09-16 |
2023-08-12 |
rat |
| E M Mintz, C F Gillespie, C L Marvel, K L Huhman, H E Alber. Serotonergic regulation of circadian rhythms in Syrian hamsters. Neuroscience. vol 79. issue 2. 1997-09-05. PMID:9200739. |
these results support the hypothesis that systemic injection of serotonergic agonists can alter circadian rhythms via action in the midbrain raphe nucleus, and that the phase shifts induced by microinjection of 8-oh-dpat into the raphe nuclei are mediated by a neurotransmitter other than serotonin within the suprachiasmatic nucleus. |
1997-09-05 |
2023-08-12 |
Not clear |
| S A Montgomer. Is there a role for a pure noradrenergic drug in the treatment of depression? European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 7 Suppl 1. 1997-07-31. PMID:9169305. |
the noradrenergic system appears to be associated with increased drive, whereas the serotonergic system relates more to changes in mood and it is possible that the different symptoms of depression may benefit from drugs acting mainly on one or other of the neurotransmitter systems. |
1997-07-31 |
2023-08-12 |
Not clear |
| S Isomoto, C Kondo, Y Kurach. Inwardly rectifying potassium channels: their molecular heterogeneity and function. The Japanese journal of physiology. vol 47. issue 1. 1997-07-17. PMID:9159640. |
girks, as heteromultimers, compose the g protein-gated kir (kg) channels, which are regulated by a variety of gi/go-coupled inhibitory neurotransmitter receptors such as m2-mus-carinic, serotonergic (5ht1a), gabab, somatostatin and opioid (mu, delta, kappa) receptors. |
1997-07-17 |
2023-08-12 |
xenopus_laevis |
| D C Jimerson, B E Wolfe, E D Metzger, D M Finkelstein, T B Cooper, J M Levin. Decreased serotonin function in bulimia nervosa. Archives of general psychiatry. vol 54. issue 6. 1997-06-27. PMID:9193193. |
evidence that serotonin-active antidepressant medications decrease binge eating in patients with bulimia nervosa has fueled interest in the hypothesis that abnormal serotonergic neurotransmitter function contributes to symptoms of the disorder. |
1997-06-27 |
2023-08-12 |
Not clear |
| P Szot, C E Reigel, S S White, R C Veit. Alterations in mRNA expression of systems that regulate neurotransmitter synaptic content in seizure-naive genetically epilepsy-prone rat (GEPR): transporter proteins and rate-limiting synthesizing enzymes for norepinephrine, dopamine and serotonin. Brain research. Molecular brain research. vol 43. issue 1-2. 1997-05-29. PMID:9037538. |
it was apparent that a straightforward correlation between neurotransmitter loss to transcriptional changes in synthesizing enzymes mrna or to re-uptake protein mrna was not observed in noradrenergic and serotonergic neurons. |
1997-05-29 |
2023-08-12 |
rat |
| D Salgado-Commissariat, K A Alkadh. Effects of serotonin on induced epileptiform activity in CA1 pyramidal neurons of genetically epilepsy prone rats. Brain research. vol 743. issue 1-2. 1997-04-17. PMID:9017248. |
the seizure susceptibility in genetically epilepsy prone rats (geprs) is reported to be caused by abnormalities in several neurotransmitter systems including the serotonergic system. |
1997-04-17 |
2023-08-12 |
rat |
| E M Seller. Biobehavioural basis of pharmacologic treatment of alcohol dependence. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. vol 2. 1997-04-07. PMID:8974377. |
this paper will review four main issues; the meaning of "craving", the role of serotonin in the neuroregulation of ethanol consumption and the effect of serotonergic drugs on ethanol intake, the role of other neurotransmitter systems, and how pharmacological treatments can be combined with psychosocial approaches. |
1997-04-07 |
2023-08-12 |
Not clear |
| A Dugar, J M Lakosk. Serotonergic function of aging hippocampal CA3 pyramidal neurons: electrophysiological assessment following administration of 5,7-dihydroxytryptamine in the fimbria-fornix and cingulum bundle. Journal of neuroscience research. vol 47. issue 1. 1997-03-26. PMID:8981238. |
serotonergic (5-hydroxytryptamine; 5-ht) neurotransmission has been implicated in the regulation of cognitive function and this neurotransmitter system may underlie selective neuronal degeneration found in the aging hippocampus. |
1997-03-26 |
2023-08-12 |
rat |
| A Shvaloff, E Neuman, D Gue. Lines of therapeutics research in Alzheimer's disease. Psychopharmacology bulletin. vol 32. issue 3. 1997-02-21. PMID:8961777. |
some recent approaches that have led to therapeutic research are identification of biochemical abnormalities, identification of dysfunction in several neurotransmitter systems (cholinergic, catecholaminergic, serotonergic, and peptidergic systems), and the study of senile plaques and neurofibrillary degeneration tangles. |
1997-02-21 |
2023-08-12 |
Not clear |
| S S Almeida, J Tonkiss, J R Galle. Malnutrition and reactivity to drugs acting in the central nervous system. Neuroscience and biobehavioral reviews. vol 20. issue 3. 1997-02-05. PMID:8880731. |
the present review will provide an overview of the literature investigating the reactivity of malnourished animals to psychoactive drugs acting through gabaergic, catecholaminergic, serotonergic, opioid and cholinergic neurotransmitter systems. |
1997-02-05 |
2023-08-12 |
human |
| S Kaspe. Clinical efficacy of mirtazapine: a review of meta-analyses of pooled data. International clinical psychopharmacology. vol 10 Suppl 4. 1997-01-08. PMID:8930007. |
its unique mode of action, involving both the noradrenergic and serotonergic neurotransmitter systems, results in strong clinical efficacy. |
1997-01-08 |
2023-08-12 |
Not clear |
| D Weinstein, D Magnuson, J Le. Altered G-protein coupling of a frontal cortical low affinity [3H]8-hydroxy-N,N-dipropyl-2-aminotetralin serotonergic binding site in Alzheimer's disease. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788528. |
based on these findings, alterations in receptor/g-protein coupling of both cholinergic and serotonergic receptors may be one explanation why neurotransmitter replacement drug therapies have been unsuccessful thus far in the treatment of ad. |
1996-12-04 |
2023-08-12 |
Not clear |
| J Hennig, H Becker, P Nette. 5-HT agonist-induced changes in peripheral immune cells in healthy volunteers: the impact of personality. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788532. |
the present study was conducted to investigate the relationship between the serotonergic neurotransmitter system and migration patterns of peripheral lymphocytes. |
1996-12-04 |
2023-08-12 |
human |
| H M Pappiu. Cortical hypometabolism in injured brain: new correlations with the noradrenergic and serotonergic systems and with behavioral deficits. Neurochemical research. vol 20. issue 11. 1996-09-25. PMID:8786817. |
this supports the hypothesis that post-injury cortical hypometabolism is a reflection of cortical functional depression in which both the serotonergic and noradrenergic neurotransmitter systems play a role, compatible with their inhibitory effects in the cortex and their postulated involvement in cortical information processing. |
1996-09-25 |
2023-08-12 |
rat |
| K D Beck, I Irwin, J Valverde, T J Brennan, J W Langston, F Heft. GDNF induces a dystonia-like state in neonatal rats and stimulates dopamine and serotonin synthesis. Neuron. vol 16. issue 3. 1996-09-20. PMID:8785063. |
our findings suggest that during development striatal gdnf regulates the capacity of dopaminergic and of serotonergic neurons for neurotransmitter production and release. |
1996-09-20 |
2023-08-12 |
rat |