All Relations between serotonergic and mesencephalon

Publication Sentence Publish Date Extraction Date Species
O Aung, Mateus R Amorim, David Mendelowitz, Vsevolod Y Polotsk. Revisiting the Role of Serotonin in Sleep-Disordered Breathing. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338762. the midbrain, pons, and medulla regions contain several serotonergic nuclei with distinct physiological roles, including regulating the hypercapnic ventilatory response, upper airway patency, and sleep-wake states. 2024-02-10 2024-02-12 Not clear
Michael B Prit. Nuclei and tracts in the epithalamus of crocodiles. The Journal of comparative neurology. 2023-07-29. PMID:37507852. the medial component is related to the limbic system and serotonergic raphe, while the lateral nucleus is more interconnected with the basal ganglia and midbrain dopamine systems. 2023-07-29 2023-08-14 Not clear
Patrizia Ambrogini, Davide Lattanzi, Marica Pagliarini, Michael Di Palma, Stefano Sartini, Riccardo Cuppini, Kjell Fuxe, Dasiel Oscar Borroto-Escuel. 5HT1AR-FGFR1 Heteroreceptor Complexes Differently Modulate GIRK Currents in the Dorsal Hippocampus and the Dorsal Raphe Serotonin Nucleus of Control Rats and of a Genetic Rat Model of Depression. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108630. the midbrain raphe serotonin (5ht) neurons provide the main ascending serotonergic projection to the forebrain, including hippocampus, which has a role in the pathophysiology of depressive disorder. 2023-04-28 2023-08-14 rat
Toshiyuki Fujita, Naoya Aoki, Chihiro Mori, Shouta Serizawa, Fumiko Kihara-Negishi, Koichi J Homma, Shinji Yamaguch. Dopaminergic nuclei in the chick midbrain express serotonin receptor subfamily genes. Frontiers in physiology. vol 13. 2022-11-25. PMID:36425295. serotonergic neurons in the dorsal and median raphe nucleus provide ascending innervation to the entire forebrain and midbrain. 2022-11-25 2023-08-14 chicken
Toshiyuki Fujita, Naoya Aoki, Chihiro Mori, Shouta Serizawa, Fumiko Kihara-Negishi, Koichi J Homma, Shinji Yamaguch. Dopaminergic nuclei in the chick midbrain express serotonin receptor subfamily genes. Frontiers in physiology. vol 13. 2022-11-25. PMID:36425295. recently, midbrain dopaminergic neurons were shown to be innervated by serotonergic neurons and modulated by 5-ht, with the crosstalk between serotonergic and dopaminergic systems attracting increased attention. 2022-11-25 2023-08-14 chicken
Nurcan Üçeyler, Mira Schließer, Dimitar Evdokimov, Jakub Radziwon, Betty Feulner, Stefan Unterecker, Florian Rimmele, Uwe Walte. Reduced midbrain raphe echogenicity in patients with fibromyalgia syndrome. PloS one. vol 17. issue 11. 2022-11-17. PMID:36395116. transcranial ultrasonography revealed anechoic alteration of midbrain raphe in depression and anxiety disorders, suggesting affection of the central serotonergic system. 2022-11-17 2023-08-14 Not clear
Els F Halff, Grazia Rutigliano, Anna Garcia-Hidalgo, Oliver D Howe. Trace amine-associated receptor 1 (TAAR1) agonism as a new treatment strategy for schizophrenia and related disorders. Trends in neurosciences. 2022-11-11. PMID:36369028. studies in rodents using taar1 knockout (taar1-ko) and overexpression models show that taar1 agonism inhibits midbrain dopaminergic and serotonergic activity, and enhances prefrontal glutamatergic function. 2022-11-11 2023-08-14 Not clear
Wei-Li Kuan, Maha Alfaidi, Catherine B Horne, Benjamin Vallin, Sarah Fox, Shaline V Fazal, Caroline H Williams-Gray, Roger A Barke. Selective neurodegeneration generated by intravenous α-synuclein pre-formed fibril administration is not associated with endogenous α-synuclein levels in the rat brain. Brain pathology (Zurich, Switzerland). 2022-11-02. PMID:36321260. our data demonstrated that a non-selective, transvascular delivery of α-synuclein pffs led to a time-dependent loss of specific populations of midbrain (but not olfactory) dopaminergic neurons, medullary (but not pontine) cholinergic neurons, and brainstem serotonergic neurons. 2022-11-02 2023-08-14 rat
Dominique F Leitner, Evgeny Kanshin, Manor Askenazi, Arline Faustin, Daniel Friedman, Sasha Devore, Beatrix Ueberheide, Thomas Wisniewski, Orrin Devinsk. Raphe and ventrolateral medulla proteomics in epilepsy and sudden unexpected death in epilepsy. Brain communications. vol 4. issue 4. 2022-08-05. PMID:35928051. to understand the potential role of brainstem nuclei in sudden unexpected death in epilepsy, we evaluated molecular signalling pathways using localized proteomics in microdissected midbrain dorsal raphe and medial medullary raphe serotonergic nuclei, as well as the ventrolateral medulla in brain tissue from epilepsy patients who died of sudden unexpected death in epilepsy and other causes in diverse epilepsy syndromes and non-epilepsy control cases ( 2022-08-05 2023-08-14 Not clear
Nancy Y A Sey, Benxia Hu, Marina Iskhakova, Sool Lee, Huaigu Sun, Neda Shokrian, Gabriella Ben Hutta, Jesse A Marks, Bryan C Quach, Eric O Johnson, Dana B Hancock, Schahram Akbarian, Hyejung Wo. Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits. Molecular psychiatry. 2022-04-15. PMID:35422469. risk genes were highly expressed in cortical glutamatergic, midbrain dopaminergic, gabaergic, and serotonergic neurons, suggesting them as relevant cell types in understanding the mechanisms by which genetic risk factors influence cigarette smoking and alcohol use. 2022-04-15 2023-08-13 Not clear
Jeffrey H Meyer, Joeffre Brag. Development and Clinical Application of Positron Emission Tomography Imaging Agents for Monoamine Oxidase B. Frontiers in neuroscience. vol 15. 2022-03-14. PMID:35280341. development and clinical application of positron emission tomography imaging agents for monoamine oxidase b. monoamine oxidase b (mao-b) is a high-density protein in the brain mainly found on outer mitochondrial membranes, primarily in astroglia, but additionally in serotonergic neurons and in the substantia nigra in the midbrain. 2022-03-14 2023-08-13 Not clear
Toshiyuki Fujita, Naoya Aoki, Chihiro Mori, Eiko Fujita, Toshiya Matsushima, Koichi J Homma, Shinji Yamaguch. Serotonergic Neurons in the Chick Brainstem Express Various Serotonin Receptor Subfamily Genes. Frontiers in physiology. vol 12. 2022-02-03. PMID:35111079. serotonergic neurons in the central nervous system, including the dorsal raphe (dr) and median raphe (mr) nuclei, are spatially clustered in the brainstem and provide ascending innervation to the entire forebrain and midbrain. 2022-02-03 2023-08-13 chicken
Olga E Redina, Vladimir N Babenko, Dmitry A Smagin, Irina L Kovalenko, Anna G Galyamina, Natalia N Kudryavtsev. Correlation of Expression Changes between Genes Controlling 5-HT Synthesis and Genes Genes. vol 12. issue 11. 2021-11-29. PMID:34828419. correlation of expression changes between genes controlling 5-ht synthesis and genes midbrain raphe nuclei (mrns) contain a large number of serotonergic neurons associated with the regulation of numerous types of psychoemotional states and physiological processes. 2021-11-29 2023-08-13 mouse
Sarah E D Davis, Jack M Sansone, Laura M Hurle. Postweaning Isolation Alters the Responses of Auditory Neurons to Serotonergic Modulation. Integrative and comparative biology. vol 61. issue 1. 2021-11-09. PMID:33974061. the serotonergic system is sensitive to social isolation in many brain regions including the inferior colliculus (ic), an auditory midbrain nucleus. 2021-11-09 2023-08-13 mouse
Dmitry A Smagin, Irina L Kovalenko, Anna G Galyamina, Irina V Belozertseva, Nikolay V Tamkovich, Konstantin O Baranov, Natalia N Kudryavtsev. Chronic Lithium Treatment Affects Anxious Behaviors and theExpression of Serotonergic Genes in Midbrain Raphe Nuclei of Defeated Male Mice. Biomedicines. vol 9. issue 10. 2021-10-26. PMID:34680410. chronic lithium treatment affects anxious behaviors and theexpression of serotonergic genes in midbrain raphe nuclei of defeated male mice. 2021-10-26 2023-08-13 mouse
Dmitry A Smagin, Irina L Kovalenko, Anna G Galyamina, Irina V Belozertseva, Nikolay V Tamkovich, Konstantin O Baranov, Natalia N Kudryavtsev. Chronic Lithium Treatment Affects Anxious Behaviors and theExpression of Serotonergic Genes in Midbrain Raphe Nuclei of Defeated Male Mice. Biomedicines. vol 9. issue 10. 2021-10-26. PMID:34680410. there is experimental evidence that chronic social defeat stress is accompanied by the development of an anxiety, development of a depression-like state, and downregulation of serotonergic genes in midbrain raphe nuclei of male mice. 2021-10-26 2023-08-13 mouse
Dmitry A Smagin, Irina L Kovalenko, Anna G Galyamina, Irina V Belozertseva, Nikolay V Tamkovich, Konstantin O Baranov, Natalia N Kudryavtsev. Chronic Lithium Treatment Affects Anxious Behaviors and theExpression of Serotonergic Genes in Midbrain Raphe Nuclei of Defeated Male Mice. Biomedicines. vol 9. issue 10. 2021-10-26. PMID:34680410. our study was aimed at investigating the effects of chronic lithium chloride (licl) administration on anxiety behavior and the expression of serotonergic genes in midbrain raphe nuclei of the affected mice. 2021-10-26 2023-08-13 mouse
Luisa Ugedo, Philippe De Deurwaerdèr. Serotonergic control of the glutamatergic neurons of the subthalamic nucleus. Progress in brain research. vol 261. 2021-10-22. PMID:33785138. numerous anatomical, electrophysiological, neurochemical and behavioral studies have reported that serotonergic neurons from the midbrain raphe nuclei modulate the activity of stn neurons. 2021-10-22 2023-08-13 Not clear
Sonali N Reisinger, Spyros Sideromenos, Orsolya Horvath, Sophia Derdak, Ana Cicvaric, Francisco J Monje, Martin Bilban, Martin Häring, Micaela Glat, Daniela D Polla. STAT3 in the dorsal raphe gates behavioural reactivity and regulates gene networks associated with psychopathology. Molecular psychiatry. vol 26. issue 7. 2021-10-16. PMID:33046834. here, we focused on the midbrain serotonergic system, a central hub for the regulation of emotions, to examine the relevance of stat3 signalling for emotional behaviour in mice by selectively knocking down raphe stat3 expression using germline genetic (stat3 ko) and viral-mediated approaches. 2021-10-16 2023-08-13 mouse
Sonali N Reisinger, Spyros Sideromenos, Orsolya Horvath, Sophia Derdak, Ana Cicvaric, Francisco J Monje, Martin Bilban, Martin Häring, Micaela Glat, Daniela D Polla. STAT3 in the dorsal raphe gates behavioural reactivity and regulates gene networks associated with psychopathology. Molecular psychiatry. vol 26. issue 7. 2021-10-16. PMID:33046834. mice lacking serotonergic stat3 presented with reduced negative behavioural reactivity and a blunted response to the sensitising effects of amphetamine, alongside alterations in midbrain neuronal firing activity of serotonergic neurons and transcriptional control of gene networks relevant for neuropsychiatric disorders. 2021-10-16 2023-08-13 mouse