| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Galter, M Böttner, K Unsicke. Developmental regulation of the serotonergic transmitter phenotype in rostral and caudal raphe neurons by transforming growth factor-betas. Journal of neuroscience research. vol 56. issue 5. 1999-07-23. PMID:10369219. |
serotonergic (5-ht) neurons of the cns develop as two separate clusters, a rostral and a caudal group, within the brain stem raphe. |
1999-07-23 |
2023-08-12 |
rat |
| V Ljubic-Thibal, A Morin, M Diksic, E Hame. Origin of the serotonergic innervation to the rat dorsolateral hypothalamus: retrograde transport of cholera toxin and upregulation of tryptophan hydroxylase mRNA expression following selective nerve terminals lesion. Synapse (New York, N.Y.). vol 32. issue 3. 1999-07-15. PMID:10340628. |
together, the present results provide the first demonstration that a discreet and selective destruction of serotonergic terminals induces a circumscribed and striking increase in tph mrna expression in a subset of brainstem serotonergic neurons projecting to and/or passing through the dlh. |
1999-07-15 |
2023-08-12 |
rat |
| M J Eaton, J A Plunkett, S Karmally, M A Martinez, K Montane. Changes in GAD- and GABA- immunoreactivity in the spinal dorsal horn after peripheral nerve injury and promotion of recovery by lumbar transplant of immortalized serotonergic precursors. Journal of chemical neuroanatomy. vol 16. issue 1. 1999-04-13. PMID:9924973. |
we have utilized rn46a cells, an immortalized neuronal cell line derived from e13 brainstem raphe, as a model for transplant of bioengineered serotonergic cells. |
1999-04-13 |
2023-08-12 |
rat |
| L D Van de Kar, M L Blai. Forebrain pathways mediating stress-induced hormone secretion. Frontiers in neuroendocrinology. vol 20. issue 1. 1999-03-23. PMID:9882535. |
the central amygdala then activates hypothalamic neurons directly, indirectly through the bed nucleus of the stria terminalis, and/or possibly via circuits involving brainstem serotonergic and catecholaminergic neurons. |
1999-03-23 |
2023-08-12 |
Not clear |
| A Panigraphy, N Zec, W Frost White, J J Filiano, H C Kinne. 3-Dimensional anatomic relationship of serotonergic and muscarinic receptor binding in the pontine reticular formation of the human infant brainstem. Clinical neuropathology. vol 17. issue 6. 1999-02-09. PMID:9832259. |
3-dimensional anatomic relationship of serotonergic and muscarinic receptor binding in the pontine reticular formation of the human infant brainstem. |
1999-02-09 |
2023-08-12 |
human |
| A Panigraphy, N Zec, W Frost White, J J Filiano, H C Kinne. 3-Dimensional anatomic relationship of serotonergic and muscarinic receptor binding in the pontine reticular formation of the human infant brainstem. Clinical neuropathology. vol 17. issue 6. 1999-02-09. PMID:9832259. |
to define better the spatial relationships between muscarinic and serotonergic receptor binding in the rostral human brainstem, we used 3-dimensional computer reconstructions of serial autoradiographs generated with radioligands to muscarinic and serotonergic receptors. |
1999-02-09 |
2023-08-12 |
human |
| F Clarac, L Vinay, J R Cazalets, J C Fady, M Jamo. Role of gravity in the development of posture and locomotion in the neonatal rat. Brain research. Brain research reviews. vol 28. issue 1-2. 1998-12-23. PMID:9795120. |
most descending pathways from the brainstem start to reach the lumbar enlargement of the spinal cord a few days before birth (reticulo-, vestibulospinal pathways as well as the serotonergic and noradrenergic projections); their development is not completed until the end of the second postnatal week. |
1998-12-23 |
2023-08-12 |
rat |
| C H Summers, E T Larson, T R Summers, K J Renner, N Greenber. Regional and temporal separation of serotonergic activity mediating social stress. Neuroscience. vol 87. issue 2. 1998-12-21. PMID:9740407. |
stressful aggressive interaction stimulates central serotonergic activation in telencephalon as well as brainstem. |
1998-12-21 |
2023-08-12 |
Not clear |
| C H Summers, E T Larson, T R Summers, K J Renner, N Greenber. Regional and temporal separation of serotonergic activity mediating social stress. Neuroscience. vol 87. issue 2. 1998-12-21. PMID:9740407. |
the patterns of serotonergic activation are so similar in hippocampus, nucleus accumbens and brainstem that a co-ordinated response may be involved in mediating short-term social stress and aggression. |
1998-12-21 |
2023-08-12 |
Not clear |
| J M Lauder, J Liu, L Devaud, A L Morro. GABA as a trophic factor for developing monoamine neurons. Perspectives on developmental neurobiology. vol 5. issue 2-3. 1998-12-16. PMID:9777640. |
the brainstem provides a good example of this relationship, since gabaergic axons pass through the anlage of the developing raphe nuclei when serotonergic (5-ht) neurons are just beginning to differentiate and migrate away from the ventricular zone. |
1998-12-16 |
2023-08-12 |
Not clear |
| M A Geye. Behavioral studies of hallucinogenic drugs in animals: implications for schizophrenia research. Pharmacopsychiatry. vol 31 Suppl 2. 1998-12-07. PMID:9754837. |
animal studies have shown that ppi is modulated by multiple interacting neurotransmitters, including dopaminergic, serotonergic, cholinergic, gabaergic, and glutamatergic systems within cortical, limbic, striatal, and brainstem structures. |
1998-12-07 |
2023-08-12 |
rat |
| M Manford, F Anderman. Complex visual hallucinations. Clinical and neurobiological insights. Brain : a journal of neurology. vol 121 ( Pt 10). 1998-11-20. PMID:9798740. |
(iii) brainstem lesions appear to affect ascending cholinergic and serotonergic pathways, and may also be implicated in parkinson's disease. |
1998-11-20 |
2023-08-12 |
human |
| b' K Masek, P Petrovick\\xc3\\xb. Morphological and pharmacological evidence for the existence of brain regulatory circuits in the immune response. International journal of immunopharmacology. vol 19. issue 9-10. 1998-09-17. PMID:9637346.' |
with the small electrolytic lesions which were placed in brain from the spinal cord through the brain stem up to the cerebral cortex we have identified a number of structures such as medial frontal cortex (area cg1-cg3), subnucleus basomedialis and centralis of amygdala, subnucleus medialis and dorsolateralis of nucleus parabrachialis, lateral part of reticular formation (monoaminergic groups a1-7) and the part of the reticular formation (serotonergic groups b6-b8) which are evidently involved in the immunomodulatory and immunoadjuvant effect of muramyl dipeptide. |
1998-09-17 |
2023-08-12 |
Not clear |
| Y W Li, D A Baylis. Presynaptic inhibition by 5-HT1B receptors of glutamatergic synaptic inputs onto serotonergic caudal raphe neurones in rat. The Journal of physiology. vol 510 ( Pt 1). 1998-09-01. PMID:9625871. |
therefore, we recorded unitary excitatory postsynaptic currents (epscs) in caudal raphe neurones (raphe obscurus and pallidus) following local electrical stimulation in a neonatal rat brainstem slice preparation; most neurones (79 %; n = 72/91) recovered following post hoc immunohistochemistry were tryptophan hydroxylase-immunoreactive, indicating that they were serotonergic. |
1998-09-01 |
2023-08-12 |
rat |
| Y Kayama, Y Koyam. Brainstem neural mechanisms of sleep and wakefulness. European urology. vol 33 Suppl 3. 1998-07-17. PMID:9599730. |
the three diffuse projection systems arising in the brainstem, that is, noradrenergic projection originating in the locus coeruleus, serotonergic projection from the dorsal raphe nucleus, and cholinergic projection from neurons gathering in the laterodorsal tegmental nucleus and scattering in the pedunculopontine tegmental nucleus, may function as controllers of sleep and wakefulness. |
1998-07-17 |
2023-08-12 |
Not clear |
| C Martin, V Roman, D Agay, M Fatôm. Anti-emetic effect of ondansetron and granisetron after exposure to mixed neutron and gamma irradiation. Radiation research. vol 149. issue 6. 1998-06-11. PMID:9611102. |
two deliveries of 5-ht3 receptor antagonists seem to disrupt serotonergic transmission at the brain stem structures and to affect the peripheral release of serotonin from the gut, thus completely preventing radiation-induced vomiting. |
1998-06-11 |
2023-08-12 |
Not clear |
| J Schoene. Cortical electrophysiology in migraine and possible pathogenetic implications. Clinical neuroscience (New York, N.Y.). vol 5. issue 1. 1998-05-13. PMID:9523052. |
the abnormal information processing is an interictal cortical dysfunction most likely due to inadequate control by the so-called "state-setting, chemically-addressed pathways" originating in the brain stem, in particular by the serotonergic pathway, leading to a low preactivation level of sensory cortices. |
1998-05-13 |
2023-08-12 |
Not clear |
| V Varga, A Kekesi, G Juhasz, B Kocsi. Reduction of the extracellular level of glutamate in the median raphe nucleus associated with hippocampal theta activity in the anaesthetized rat. Neuroscience. vol 84. issue 1. 1998-05-08. PMID:9522361. |
the present data complete those found earlier indicating that the desynchronizing serotonergic influence originating from the brainstem is maintained by a tonic excitatory input to the median raphe nucleus. |
1998-05-08 |
2023-08-12 |
rat |
| J A Hobson, R Stickgold, E F Pace-Schot. The neuropsychology of REM sleep dreaming. Neuroreport. vol 9. issue 3. 1998-04-29. PMID:9512371. |
the pontine brainstem mechanisms controlling the neuromodulatory balance of the brain in rats and cats include noradrenergic and serotonergic influences which enhance waking and impede rem via anticholinergic mechanisms and cholinergic mechanisms which are essential to rem sleep and only come into full play when the serotonergic and noradrenergic systems are inhibited. |
1998-04-29 |
2023-08-12 |
human |
| A Heils, C Wichems, R Mössner, S Petri, K Glatz, D Bengel, D L Murphy, K P Lesc. Functional characterization of the murine serotonin transporter gene promoter in serotonergic raphe neurons. Journal of neurochemistry. vol 70. issue 3. 1998-03-12. PMID:9489712. |
a approximately 2.2-kb fragment (-2,143 to +51 with respect to the transcription start site), which had been fused to the luciferase reporter gene and transiently expressed in a 5-htt-expressing cell line and in serotonergic raphe neurons derived from embryonic rat brainstem, displayed both constitutive and inducible promoter activity. |
1998-03-12 |
2023-08-12 |
rat |