| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jordan D T Engbers, Fernando R Fernandez, Ray W Turne. Bistability in Purkinje neurons: ups and downs in cerebellar research. Neural networks : the official journal of the International Neural Network Society. vol 47. 2014-04-21. PMID:23041207. |
bistability in purkinje neurons: ups and downs in cerebellar research. |
2014-04-21 |
2023-08-12 |
Not clear |
| Volker Steuber, Dieter Jaege. Modeling the generation of output by the cerebellar nuclei. Neural networks : the official journal of the International Neural Network Society. vol 47. 2014-04-21. PMID:23200193. |
here, input from purkinje cells converges to control cn neuron spiking via gabaergic inhibition, before the output from the cn reaches cerebellar targets such as the brainstem and the motor thalamus. |
2014-04-21 |
2023-08-12 |
Not clear |
| Ludovico Silvestri, Alessandro Bria, Irene Costantini, Leonardo Sacconi, Hanchuan Peng, Giulio Iannello, Francesco Saverio Pavon. Micron-scale resolution optical tomography of entire mouse brains with confocal light sheet microscopy. Journal of visualized experiments : JoVE. issue 80. 2014-04-21. PMID:24145191. |
finally, we illustrated some example of brain maps: the cerebellum from an l7-gfp transgenic mouse, in which all purkinje cells are selectively labeled, and the whole brain from a thy1-gfp-m mouse, characterized by a random sparse neuronal labeling. |
2014-04-21 |
2023-08-12 |
mouse |
| Steven Si Feng, Risa Lin, Volker Gauck, Dieter Jaege. Gain control of synaptic response function in cerebellar nuclear neurons by a calcium-activated potassium conductance. Cerebellum (London, England). vol 12. issue 5. 2014-04-10. PMID:23605187. |
we examined whether inhibitory input processing is also dependent on sk current in the cerebellar nuclei (cn) where inhibition provides the only route of information transfer from the cerebellar cortical purkinje cells. |
2014-04-10 |
2023-08-12 |
Not clear |
| Rebecca McFarland, Hadi S Zanjani, Jean Mariani, Michael W Voge. Changes in the Distribution of the α 3 Na(+)/K(+) ATPase Subunit in Heterozygous Lurcher Purkinje Cells as a Genetic Model of Chronic Depolarization during Development. International journal of cell biology. vol 2014. 2014-04-10. PMID:24719618. |
the results suggest that the expression of the catalytic α 3 subunit is altered in chronically depolarized +/lc purkinje cells, although the density of active na(+)/k(+) atpase pumps is not significantly altered compared with wt in the cerebellar cortex at p15, and then declines from p15 to p25 in the +/lc cerebellum as the +/lc purkinje cells degenerate. |
2014-04-10 |
2023-08-13 |
Not clear |
| Richard Garrett Key, James C Roo. Anti-Yo mediated paraneoplastic cerebellar degeneration in the context of breast cancer: a case report and literature review. Psycho-oncology. vol 22. issue 9. 2014-04-01. PMID:23585287. |
paraneoplastic cerebellar degeneration (pcd) is a paraneoplastic syndrome which destroys purkinje cells of the cerebellum and causes trunk and limb ataxia, dysarthria, diplopia, and vertigo, which often precede the diagnosis of cancer. |
2014-04-01 |
2023-08-12 |
Not clear |
| Yoshiaki Kita, Koichi Kawakami, Yoshiko Takahashi, Fujio Murakam. Development of cerebellar neurons and glias revealed by in utero electroporation: Golgi-like labeling of cerebellar neurons and glias. PloS one. vol 8. issue 7. 2014-03-27. PMID:23894597. |
five types of cerebellar neurons, namely purkinje, golgi, lugaro and unipolar brush cells, large-diameter deep nuclei (dn) neurons, and dn astrocytes were labeled by conventional plasmids, whereas plasmids that enable permanent labeling additionally labeled stellate, basket, and granule cells as well as three types of glias. |
2014-03-27 |
2023-08-12 |
mouse |
| Teddy Fauquier, Fabrice Chatonnet, Frédéric Picou, Sabine Richard, Nicolas Fossat, Nadine Aguilera, Thomas Lamonerie, Frédéric Flaman. Purkinje cells and Bergmann glia are primary targets of the TRα1 thyroid hormone receptor during mouse cerebellum postnatal development. Development (Cambridge, England). vol 141. issue 1. 2014-03-11. PMID:24346699. |
purkinje cells and bergmann glia are primary targets of the trα1 thyroid hormone receptor during mouse cerebellum postnatal development. |
2014-03-11 |
2023-08-12 |
mouse |
| José Javier Otero, Ilona Kalaszczynska, Wojciech Michowski, Michael Wong, Patrick Edwin Gygli, Hamza Numan Gokozan, Amélie Griveau, Junko Odajima, Catherine Czeisler, Fay Patsy Catacutan, Alice Murnen, Ulrich Schüller, Piotr Sicinski, David Rowitc. Cerebellar cortical lamination and foliation require cyclin A2. Developmental biology. vol 385. issue 2. 2014-03-06. PMID:24184637. |
compound conditional loss of cyclin a1/a2 in neural progenitors resulted in severe cerebellar hypoplasia, decreased proliferation of cerebellar granule neuron progenitors (cgnp), and purkinje (pc) neuron dyslamination. |
2014-03-06 |
2023-08-12 |
Not clear |
| Kotaro Kawanishi, Mitsuya Morita, Keiichi Nakahara, Syuichi Tetsuka, Tom Kouki, Kaoru Tominaga, Hitoshi Endo, Takashi Yashiro, Keiko Tanaka, Imaharu Nakan. [Paraneoplastic cerebellar degeneration with bladder cancer confirmed the existence of an anti-neural antibody: a case report]. Brain and nerve = Shinkei kenkyu no shinpo. vol 65. issue 11. 2014-03-06. PMID:24200618. |
immunohistochemical staining of mouse cerebellum using the patient's serum revealed coarse granular staining in the cytoplasm of purkinje cells and diffuse staining in the neuropil of the molecular layer, suggesting the presence of an unknown antibody. |
2014-03-06 |
2023-08-12 |
mouse |
| Jeong-Won Jeong, Vijay N Tiwari, Michael E Behen, Harry T Chugani, Diane C Chugan. In vivo detection of reduced Purkinje cell fibers with diffusion MRI tractography in children with autistic spectrum disorders. Frontiers in human neuroscience. vol 8. 2014-03-04. PMID:24592234. |
postmortem neuropathology studies report reduced number and size of purkinje cells (pc) in a majority of cerebellar specimens from persons diagnosed with autism spectrum disorders (asd). |
2014-03-04 |
2023-08-12 |
human |
| Arnulf H Koeppen, R Liane Ramirez, Sarah T Bjork, Peter Bauer, Paul J Feuste. The reciprocal cerebellar circuitry in human hereditary ataxia. Cerebellum (London, England). vol 12. issue 4. 2014-03-03. PMID:23389921. |
a new way to study cerebellar ataxia is the systematic analysis of the "reciprocal cerebellar circuitry" that consists of tightly organized reciprocal connections between purkinje cells, dentate nuclei (dn), and inferior olivary nuclei (ion). |
2014-03-03 |
2023-08-12 |
human |
| Tiffany D Rogers, Price E Dickson, Eric McKimm, Detlef H Heck, Dan Goldowitz, Charles D Blaha, Guy Mittlema. Reorganization of circuits underlying cerebellar modulation of prefrontal cortical dopamine in mouse models of autism spectrum disorder. Cerebellum (London, England). vol 12. issue 4. 2014-03-03. PMID:23436049. |
the present study compared functional adaptations of cerebello-cortical circuitry following developmental cerebellar pathology in a mouse model of developmental loss of purkinje cells (lurcher) and a mouse model of fragile x syndrome (fmr1 ko mice). |
2014-03-03 |
2023-08-12 |
mouse |
| M Xu, Z L Sulkowski, P Parekh, A Khan, T Chen, S Midha, T Iwasaki, N Shimokawa, N Koibuchi, A M Zavacki, E M Sajdel-Sulkowsk. Effects of perinatal lipopolysaccharide (LPS) exposure on the developing rat brain; modeling the effect of maternal infection on the developing human CNS. Cerebellum (London, England). vol 12. issue 4. 2014-03-03. PMID:23475384. |
in vitro chronic exposure of cerebellar cultures to lps resulted in decreased arborization of purkinje cells while d2 was only increased transiently. |
2014-03-03 |
2023-08-12 |
human |
| Janneth Oleas, Fumiaki Yokoi, Mark P DeAndrade, Antonio Pisani, Yuqing L. Engineering animal models of dystonia. Movement disorders : official journal of the Movement Disorder Society. vol 28. issue 7. 2014-02-26. PMID:23893455. |
interestingly, loss of the dyt1 dystonia causal protein in purkinje cells shows an improvement in motor performance, suggesting that gene therapy targeting of the cerebellum or intervention in its downstream pathways may be useful. |
2014-02-26 |
2023-08-12 |
mouse |
| Jean Laurens, Hui Meng, Dora E Angelak. Neural representation of orientation relative to gravity in the macaque cerebellum. Neuron. vol 80. issue 6. 2014-02-24. PMID:24360549. |
here we identify a group of purkinje cells in the caudal cerebellar vermis with responses that reflect an estimate of head tilt. |
2014-02-24 |
2023-08-12 |
monkey |
| Kazuhisa Kohda, Wataru Kakegawa, Michisuke Yuzak. Unlocking the secrets of the δ2 glutamate receptor: A gatekeeper for synaptic plasticity in the cerebellum. Communicative & integrative biology. vol 6. issue 6. 2014-02-24. PMID:24563706. |
interestingly, cerebellar ltd, which occurs at synapses between parallel fibers (pfs; axons of granule cells) and purkinje cells, is unique in requiring an additional type of glutamate receptor, the δ2 receptor (glud2). |
2014-02-24 |
2023-08-12 |
Not clear |
| Romain Ly, Guy Bouvier, Martijn Schonewille, Arnaud Arabo, Laure Rondi-Reig, Clément Léna, Mariano Casado, Chris I De Zeeuw, Anne Felt. T-type channel blockade impairs long-term potentiation at the parallel fiber-Purkinje cell synapse and cerebellar learning. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 50. 2014-02-21. PMID:24277825. |
cav3.1 t-type channels are abundant at the cerebellar synapse between parallel fibers and purkinje cells where they contribute to synaptic depolarization. |
2014-02-21 |
2023-08-12 |
mouse |
| G Urkasemsin, K E Linder, J S Bell, A de Lahunta, N J Olb. Mapping of Purkinje neuron loss and polyglucosan body accumulation in hereditary cerebellar degeneration in Scottish terriers. Veterinary pathology. vol 49. issue 5. 2014-02-19. PMID:21753036. |
the aims of this study were to describe and quantify polyglucosan body accumulation and quantify purkinje neurons in the cerebellum of affected and control dogs. |
2014-02-19 |
2023-08-12 |
dog |
| G Urkasemsin, K E Linder, J S Bell, A de Lahunta, N J Olb. Mapping of Purkinje neuron loss and polyglucosan body accumulation in hereditary cerebellar degeneration in Scottish terriers. Veterinary pathology. vol 49. issue 5. 2014-02-19. PMID:21753036. |
counts of purkinje neurons and polyglucosan bodies were performed in control and affected dogs on cerebellar sections stained with periodic acid-schiff. |
2014-02-19 |
2023-08-12 |
dog |