| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Servais, G Chero. Purkinje cell rhythmicity and synchronicity during modulation of fast cerebellar oscillation. Neuroscience. vol 134. issue 4. 2005-11-15. PMID:16054763. |
we propose that fast cerebellar oscillation is due to the synchronous rhythmic firing of purkinje cell populations and is facilitated by positive feedback whereby the oscillating field further phase-locks recruited purkinje cells onto the same rhythmic firing pattern. |
2005-11-15 |
2023-08-12 |
mouse |
| E Yan, M Castillo-Meléndez, G Smythe, D Walke. Quinolinic acid promotes albumin deposition in Purkinje cell, astrocytic activation and lipid peroxidation in fetal brain. Neuroscience. vol 134. issue 3. 2005-11-14. PMID:16026935. |
at 24 h after quin infusion glial fibrillary acidic protein immunoreactivity was significantly increased in cerebral gray matter and the granule cell layer of cerebellum, and the lipid peroxide product 4-hydroxynonenal-immunoreactivity and albumin-immunoreactivity were present throughout the cytoplasm of cerebellar purkinje cells. |
2005-11-14 |
2023-08-12 |
Not clear |
| Silvia H Madalosso, Eva M Pérez-Villegas, José A Armengo. Naturally occurring neuronal death during the postnatal development of Purkinje cells and their precerebellar afferent projections. Brain research. Brain research reviews. vol 49. issue 2. 2005-11-14. PMID:16111555. |
thus, studies on adult cerebellar neuronal cell death occurring in mouse mutants elucidate: (i) the dependence of the postsynaptic neurons on their partners, (ii) the 'en cascade' postsynaptic transneuronal degeneration after target-deprivation, and (iii) the close relationship between the molecular modular organization of the cerebellar cortex and dying purkinje cells. |
2005-11-14 |
2023-08-12 |
mouse |
| Silvia H Madalosso, Eva M Pérez-Villegas, José A Armengo. Naturally occurring neuronal death during the postnatal development of Purkinje cells and their precerebellar afferent projections. Brain research. Brain research reviews. vol 49. issue 2. 2005-11-14. PMID:16111555. |
in the present review, we correlate the dates of purkinje cells death with the inferior olivary and basilar pontine neuronal apoptosis, discussing their developmental relationships during the elaboration of the fine-grained maps of the cerebellar afferent connections. |
2005-11-14 |
2023-08-12 |
mouse |
| I Dusart, A Ghoumari, R Wehrle, M P Morel, L Bouslama-Oueghlani, E Camand, C Sotel. Cell death and axon regeneration of Purkinje cells after axotomy: challenges of classical hypotheses of axon regeneration. Brain research. Brain research reviews. vol 49. issue 2. 2005-11-14. PMID:16111558. |
this is particularly well illustrated in the cerebellar system, in which axotomized inferior olivary neurons regenerate when confronted with a permissive environment, whereas mature purkinje cells do not. |
2005-11-14 |
2023-08-12 |
Not clear |
| Kenji Takatsuka, Takahiro M Ishii, Harunori Ohmor. A novel Ca2+ indicator protein using FRET and calpain-sensitive linker. Biochemical and biophysical research communications. vol 336. issue 1. 2005-11-14. PMID:16129417. |
unexpectedly, f2c was not cleaved by calpain, but demonstrated properties of a ca(2+) indicator when transiently infected in purkinje cells of rat primary cerebellar culture or in the brainstem neurons infected in vivo using sindbis virus encoding f2c. |
2005-11-14 |
2023-08-12 |
rat |
| Kendra I Siler-Marsiglio, Michael Paiva, Irina Madorsky, Qun Pan, Gerry Shaw, Marieta B Heato. Functional mechanisms of apoptosis-related proteins in neonatal rat cerebellum are differentially influenced by ethanol at postnatal days 4 and 7. Journal of neuroscience research. vol 81. issue 5. 2005-11-01. PMID:16035105. |
for these analyses, we addressed the following questions, by using p4 and p7 cerebellar tissue following in vivo exposure: 1) are there differential patterns of expression of antiapoptotic bcl-2 or proapoptotic bax in etoh-vulnerable purkinje cells that could contribute to the different degrees of temporal etoh vulnerability? |
2005-11-01 |
2023-08-12 |
rat |
| Rosemarie Drake-Bauman. Rapid modulation of inhibitory synaptic currents in cerebellar Purkinje cells by BDNF. Synapse (New York, N.Y.). vol 57. issue 4. 2005-10-27. PMID:15986361. |
the present study examined the acute effects of exogenous bdnf on inhibitory synaptic currents in purkinje cells in cerebellar cultures. |
2005-10-27 |
2023-08-12 |
Not clear |
| Roberta Cesa, Laura Morando, Piergiorgio Strat. Purkinje cell spinogenesis during architectural rewiring in the mature cerebellum. The European journal of neuroscience. vol 22. issue 3. 2005-10-27. PMID:16101739. |
following a lesion of rat olivocerebellar axons, by severing the inferior cerebellar peduncle, new spines grow on the deafferented proximal dendrite of the purkinje cells (pcs) and these new spines become innervated by parallel fibres (pfs) that normally contact only the distal dendrites. |
2005-10-27 |
2023-08-12 |
mouse |
| Tatsuya Takahashi, Nobutaka Arai, Megumi Shimamura, Yume Suzuki, Sumimasa Yamashita, Hiroko Iwamoto, Yoshiaki Inayama, Youichi Kameda, Yoshiyuki Kuroiw. Autopsy case of acute encephalopathy linked to familial hemiplegic migraine with cerebellar atrophy and mental retardation. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 25. issue 3. 2005-10-27. PMID:16193840. |
these changes may be characteristic of familial hemiplegic migraine with cerebellar atrophy, as well as the other metabolic diseases, such as menkes' kinky hair disease, infantile (tay-sachs type) amaurotic idiocy, organic mercury intoxication, and mitochondrial encephalopathy, of which cases often exhibit such pathological changes of purkinje cells. |
2005-10-27 |
2023-08-12 |
Not clear |
| Fumihito Saitow, Takayuki Murakoshi, Hidenori Suzuki, Shiro Konish. Metabotropic P2Y purinoceptor-mediated presynaptic and postsynaptic enhancement of cerebellar GABAergic transmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 8. 2005-10-26. PMID:15728851. |
here, we investigated roles of metabotropic p2y purinoceptors (p2yrs) on gabaergic synapses between cerebellar interneurons and purkinje cells (pcs). |
2005-10-26 |
2023-08-12 |
rat |
| Cs Vastagh, J Víg, J Hámori, J Takác. Delayed postnatal settlement of cerebellar Purkinje cells in vermal lobules VI and VII of the mouse. Anatomy and embryology. vol 209. issue 6. 2005-10-11. PMID:15887047. |
the postnatal development of the ganglionic (purkinje) layer was studied in the mouse cerebellum from p0 to young adulthood with special emphasis to vermal lobules vi-vii (oculomotor vermis) in the mouse. |
2005-10-11 |
2023-08-12 |
mouse |
| Catherine M Watson, Gregory J Pelka, Tatiana Radziewic, Mona D Shahbazian, John Christodoulou, Sarah L Williamson, Patrick P L Ta. Reduced proportion of Purkinje cells expressing paternally derived mutant Mecp2308 allele in female mouse cerebellum is not due to a skewed primary pattern of X-chromosome inactivation. Human molecular genetics. vol 14. issue 13. 2005-10-11. PMID:15888476. |
reduced proportion of purkinje cells expressing paternally derived mutant mecp2308 allele in female mouse cerebellum is not due to a skewed primary pattern of x-chromosome inactivation. |
2005-10-11 |
2023-08-12 |
mouse |
| Catherine M Watson, Gregory J Pelka, Tatiana Radziewic, Mona D Shahbazian, John Christodoulou, Sarah L Williamson, Patrick P L Ta. Reduced proportion of Purkinje cells expressing paternally derived mutant Mecp2308 allele in female mouse cerebellum is not due to a skewed primary pattern of X-chromosome inactivation. Human molecular genetics. vol 14. issue 13. 2005-10-11. PMID:15888476. |
at 20 weeks of age, there was no significant difference between xci patterns in the purkinje cells in the cerebellum of heterozygous mutant and wild-type mice when the mutant allele was inherited from the mother. |
2005-10-11 |
2023-08-12 |
mouse |
| S K E Koekkoek, K Yamaguchi, B A Milojkovic, B R Dortland, T J H Ruigrok, R Maex, W De Graaf, A E Smit, F VanderWerf, C E Bakker, R Willemsen, T Ikeda, S Kakizawa, K Onodera, D L Nelson, E Mientjes, M Joosten, E De Schutter, B A Oostra, M Ito, C I De Zeeu. Deletion of FMR1 in Purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in Fragile X syndrome. Neuron. vol 47. issue 3. 2005-10-11. PMID:16055059. |
deletion of fmr1 in purkinje cells enhances parallel fiber ltd, enlarges spines, and attenuates cerebellar eyelid conditioning in fragile x syndrome. |
2005-10-11 |
2023-08-12 |
mouse |
| Shigeyuki Namiki, Sho Kakizawa, Kenzo Hirose, Masamitsu Iin. NO signalling decodes frequency of neuronal activity and generates synapse-specific plasticity in mouse cerebellum. The Journal of physiology. vol 566. issue Pt 3. 2005-10-05. PMID:15919714. |
the indicator (hbr-gfp) was expressed in the purkinje cells of the mouse cerebellum and we imaged no signals in acute cerebellar slices upon parallel fibre (pf) activation with a train of burst stimulations (bs, each bs consisting of five pulses at 50 hz). |
2005-10-05 |
2023-08-12 |
mouse |
| Jae-Sung Bae, Shigeki Furuya, Yoko Shinoda, Shogo Endo, Edward H Schuchman, Yoshio Hirabayashi, Hee Kyung Ji. Neurodegeneration augments the ability of bone marrow-derived mesenchymal stem cells to fuse with Purkinje neurons in Niemann-Pick type C mice. Human gene therapy. vol 16. issue 8. 2005-10-04. PMID:16076258. |
here we demonstrate that the pathology associated with murine niemann-pick disease type c (np-c) cerebellum augments the ability of bm-mscs to fuse with purkinje neurons. |
2005-10-04 |
2023-08-12 |
mouse |
| Jae-Sung Bae, Shigeki Furuya, Yoko Shinoda, Shogo Endo, Edward H Schuchman, Yoshio Hirabayashi, Hee Kyung Ji. Neurodegeneration augments the ability of bone marrow-derived mesenchymal stem cells to fuse with Purkinje neurons in Niemann-Pick type C mice. Human gene therapy. vol 16. issue 8. 2005-10-04. PMID:16076258. |
the results suggest that the degenerative microenvironment of purkinje neurons in the np-c cerebellum modulates the cell fate switch of bm-mscs via cell fusion. |
2005-10-04 |
2023-08-12 |
mouse |
| Jaideep Goswami, Loren A Martin, Daniel Goldowitz, Alvin J Beitz, Rod M Fedderse. Enhanced Purkinje cell survival but compromised cerebellar function in targeted anti-apoptotic protein transgenic mice. Molecular and cellular neurosciences. vol 29. issue 2. 2005-10-03. PMID:15911345. |
interestingly, rotarod behavioral analysis demonstrated that 'rescued' purkinje cells degrade cerebellar function. |
2005-10-03 |
2023-08-12 |
mouse |
| Cynthia A Dlugo. Analyses of smooth endoplasmic reticulum of cerebellar parallel fibers in aging, ethanol-fed rats. Alcohol (Fayetteville, N.Y.). vol 35. issue 1. 2005-09-29. PMID:15922139. |
these findings support the suggestions that (1) parallel fiber ser, unlike the ser in purkinje neurons, is insensitive to ethanol and (2) the mechanisms by which ethanol and aging alter cerebellar function and structure are different. |
2005-09-29 |
2023-08-12 |
rat |