| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yi Zhang, Xuenong Bo, Ralf Schoepfer, Anthony J D G Holtmaat, Joost Verhaagen, Piers C Emson, A Robert Lieberman, Patrick N Anderso. Growth-associated protein GAP-43 and L1 act synergistically to promote regenerative growth of Purkinje cell axons in vivo. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 41. 2006-04-20. PMID:16195382. |
transgenic mice were generated in which purkinje cells constitutively express l1 or both l1 and gap-43 under the purkinje cell-specific l7 promoter, and regeneration of purkinje cell axons into peripheral nerve grafts implanted into the cerebellum was examined. |
2006-04-20 |
2023-08-12 |
mouse |
| Jean-Marc Fritschy, Patrizia Panzanelli, Jason E Kralic, Kaspar E Vogt, Marco Sassoè-Pognett. Differential dependence of axo-dendritic and axo-somatic GABAergic synapses on GABAA receptors containing the alpha1 subunit in Purkinje cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 12. 2006-04-14. PMID:16554475. |
in the cerebellum, purkinje cells (pcs) receive gabaergic, axo-dendritic synapses from stellate cells and axo-somatic synapses from basket cells, both with gabaa receptors containing the alpha1 subunit. |
2006-04-14 |
2023-08-12 |
mouse |
| Frank Van Calenbergh, Nikolaas Vantomme, Patrick Flamen, Philippe Demaerel, Raf Sciot, Erik Legius, Luc Mortelmans, Christian Plet. Lhermitte-Duclos disease: 11C-methionine positron emission tomography data in 4 patients. Surgical neurology. vol 65. issue 3. 2006-04-10. PMID:16488255. |
lhermitte-duclos disease is a cerebellar lesion, characterized by an overgrowth of cerebellar ganglion cells, which replace granular cells and purkinje cells. |
2006-04-10 |
2023-08-12 |
Not clear |
| Matthieu Delescluse, Christophe Pouza. Efficient spike-sorting of multi-state neurons using inter-spike intervals information. Journal of neuroscience methods. vol 150. issue 1. 2006-04-03. PMID:16085317. |
we demonstrate the efficacy of a new spike-sorting method based on a markov chain monte carlo (mcmc) algorithm by applying it to real data recorded from purkinje cells (pcs) in young rat cerebellar slices. |
2006-04-03 |
2023-08-12 |
rat |
| Genaro Patiño-Lopez, Peter Hevezi, Jerry Lee, Dorian Willhite, Gail M Verge, Sandra M Lechner, Vianney Ortiz-Navarrete, Albert Zlotni. Human class-I restricted T cell associated molecule is highly expressed in the cerebellum and is a marker for activated NKT and CD8+ T lymphocytes. Journal of neuroimmunology. vol 171. issue 1-2. 2006-03-30. PMID:16300832. |
here we further characterize human crtam and find that it is highly expressed in the cerebellum, notably in purkinje neurons. |
2006-03-30 |
2023-08-12 |
human |
| E Ilijic, A Guidotti, E Mugnain. Moving up or moving down? Malpositioned cerebellar unipolar brush cells in reeler mouse. Neuroscience. vol 136. issue 3. 2006-03-30. PMID:16344141. |
in the reeler cerebellum, which is small and lacks foliation, purkinje cells are greatly reduced in number and in large part are located ectopically in deep cerebellar masses. |
2006-03-30 |
2023-08-12 |
mouse |
| Marieta Barrow Heaton, Michael Paiva, Irina Madorsky, Kendra Siler-Marsiglio, Gerry Sha. Effect of bax deletion on ethanol sensitivity in the neonatal rat cerebellum. Journal of neurobiology. vol 66. issue 1. 2006-03-21. PMID:16215995. |
bax knock-out and wild-type mice pups were exposed to ethanol via vapor inhalation during the maximal period of neonatal cerebellar ethanol sensitivity and cerebellar tissue was subsequently assessed for purkinje and granule cell number and ethanol-mediated generation of reactive oxygen species (ros). |
2006-03-21 |
2023-08-12 |
mouse |
| Marieta Barrow Heaton, Michael Paiva, Irina Madorsky, Kendra Siler-Marsiglio, Gerry Sha. Effect of bax deletion on ethanol sensitivity in the neonatal rat cerebellum. Journal of neurobiology. vol 66. issue 1. 2006-03-21. PMID:16215995. |
the results revealed that: (1) ethanol exposure during the peak period of cerebellar vulnerability resulted in substantial loss of purkinje cells in wild-type animals, but not in bax knock-outs; (2) granule cells in the bax gene-deleted animals were not similarly protected from ethanol effects; and (3) levels of ros following acute ethanol exposure were appreciably enhanced in the wild-type animals but not in the bax knock-outs. |
2006-03-21 |
2023-08-12 |
mouse |
| Jianfeng Xiao, Mark S Ledou. Caytaxin deficiency causes generalized dystonia in rats. Brain research. Molecular brain research. vol 141. issue 2. 2006-03-21. PMID:16246457. |
in cerebellum, atcay transcript was present in the molecular, purkinje and granular layers; transcript density in the molecular layer peaked at p14. |
2006-03-21 |
2023-08-12 |
rat |
| N I Sharonova, V S Vorob'ev, V G Skrebitskii, A P Galenko-Yaroshevskii, A Yu Turovaya, V A Anisimov. Potentiation of GABA-activated currents by imidazobenzoimidazole derivative RU-353 in isolated cerebellum Purkinje cells. Bulletin of experimental biology and medicine. vol 140. issue 3. 2006-03-21. PMID:16307050. |
voltage clamp and concentration jump experiments performed on purkinje cells isolated from rat cerebellum showed that novel imidazobenzoimidazole derivative ru-353 increased the amplitude of gaba-activated chlorine current in a dose-dependent manner (ec50=15 microm for the currents activated by 1 microm gaba). |
2006-03-21 |
2023-08-12 |
rat |
| Jacques I Wadiche, Anastassios V Tzingounis, Craig E Jah. Intrinsic kinetics determine the time course of neuronal synaptic transporter currents. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 4. 2006-03-17. PMID:16418298. |
in the cerebellum, clearance of glutamate relies on uptake by bergmann glial cells and purkinje cells (pcs). |
2006-03-17 |
2023-08-12 |
Not clear |
| Robert E Sims, Nicholas A Hartel. Differences in transmission properties and susceptibility to long-term depression reveal functional specialization of ascending axon and parallel fiber synapses to Purkinje cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 12. 2006-03-14. PMID:15788782. |
an understanding of the patterns of mossy fiber transmission to purkinje cells, via granule cell axons, is fundamental to models of cerebellar cortical signaling and processing. |
2006-03-14 |
2023-08-12 |
Not clear |
| M Tsirigotis, M Y Tang, M Beyers, M Zhang, J Woulfe, D A Gra. Delayed spinocerebellar ataxia in transgenic mice expressing mutant ubiquitin. Neuropathology and applied neurobiology. vol 32. issue 1. 2006-03-14. PMID:16409551. |
spinocerebellar ataxia type 1 (sca1) is an incurable neurodegenerative disease resulting from loss of purkinje neurones within the cerebellum. |
2006-03-14 |
2023-08-12 |
mouse |
| Christelle Gras, Jacqueline Vinatier, Bénédicte Amilhon, Aline Guerci, Christo Christov, Philippe Ravassard, Bruno Giros, Salah El Mestikaw. Developmentally regulated expression of VGLUT3 during early post-natal life. Neuropharmacology. vol 49. issue 6. 2006-03-10. PMID:16182324. |
we further analyzed the transient expression of vglut3 in the cerebellum and found it to correspond to a temporary expression in purkinje cells. |
2006-03-10 |
2023-08-12 |
rat |
| Pratap Meera, Paul D Dodson, Movses H Karakossian, Thomas S Oti. Expression of GFP-tagged neuronal glutamate transporters in cerebellar Purkinje neurons. Neuropharmacology. vol 49. issue 6. 2006-03-10. PMID:16212990. |
two-photon microscopy was used to examine fusion protein expression in purkinje neurons in acute cerebellar slices. |
2006-03-10 |
2023-08-12 |
Not clear |
| Anna-Lena Ström, Lars Forsgren, Monica Holmber. A role for both wild-type and expanded ataxin-7 in transcriptional regulation. Neurobiology of disease. vol 20. issue 3. 2006-03-09. PMID:15936949. |
spinocerebellar ataxia type 7 (sca7) is a neurodegenerative disease primarily affecting the brainstem, retina and purkinje cells of the cerebellum. |
2006-03-09 |
2023-08-12 |
Not clear |
| Isidre Ferrer, Josef P Kapfhammer, Colette Hindelang, Stephan Kemp, Nathalie Troffer-Charlier, Vania Broccoli, Noëlle Callyzot, Petra Mooyer, Jacqueline Selhorst, Peter Vreken, Ronald J A Wanders, Jean Louis Mandel, Aurora Pujo. Inactivation of the peroxisomal ABCD2 transporter in the mouse leads to late-onset ataxia involving mitochondria, Golgi and endoplasmic reticulum damage. Human molecular genetics. vol 14. issue 23. 2006-03-07. PMID:16223892. |
the main pathological feature in abcd2-/- mice is a late-onset cerebellar and sensory ataxia, with loss of cerebellar purkinje cells and dorsal root ganglia cell degeneration, correlating with accumulation of vlcfas in the latter cellular population. |
2006-03-07 |
2023-08-12 |
mouse |
| Michael L Molineux, Fernando R Fernandez, W Hamish Mehaffey, Ray W Turne. A-type and T-type currents interact to produce a novel spike latency-voltage relationship in cerebellar stellate cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 47. 2006-03-07. PMID:16306399. |
spike timing in stellate cells could be particularly important to cerebellar output, because the discharge of even single spikes can significantly delay spike discharge in postsynaptic purkinje cells. |
2006-03-07 |
2023-08-12 |
Not clear |
| Natalia Lozovaya, Natalia Yatsenko, Andrey Beketov, Timur Tsintsadze, Nail Burnashe. Glycine receptors in CNS neurons as a target for nonretrograde action of cannabinoids. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 33. 2006-03-02. PMID:16107637. |
in isolated hippocampal pyramidal and purkinje cerebellar neurons, endogenous cannabinoids anandamide and 2-arachidonylglycerol, applied at physiological concentrations, inhibited the amplitude and altered the kinetics of rise time, desensitization, and deactivation of the glycine-activated current (i(gly)) in a concentration-dependent manner. |
2006-03-02 |
2023-08-12 |
Not clear |
| Beatrice Argenti, Rita Gallo, Lucia Di Marcotullio, Elisabetta Ferretti, Maddalena Napolitano, Sonia Canterini, Enrico De Smaele, Azzura Greco, Maria Teresa Fiorenza, Marella Maroder, Isabella Screpanti, Edoardo Alesse, Alberto Gulin. Hedgehog antagonist REN(KCTD11) regulates proliferation and apoptosis of developing granule cell progenitors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 36. 2006-03-02. PMID:16148242. |
during the early development of the cerebellum, a burst of granule cell progenitor (gcp) proliferation occurs in the outer external granule layer (egl), which is sustained mainly by purkinje cell-derived sonic hedgehog (shh). |
2006-03-02 |
2023-08-12 |
human |