| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kálmán Magyar, Béla Szend. (-)-Deprenyl, a selective MAO-B inhibitor, with apoptotic and anti-apoptotic properties. Neurotoxicology. vol 25. issue 1-2. 2004-04-01. PMID:14697898. |
(-)-deprenyl potentiates the effect of dopamine, it has antioxidant activity and prevents the toxicity of the dopaminergic (6-oh-dopamine; 1-methyl-4-phenyl-1,2,3,6-tetrahydro-pyridine (mptp)), the noradrenergic (dsp-4) and cholinergic (af64a) neurotoxins after pre-treatment. |
2004-04-01 |
2023-08-12 |
human |
| Elisa Mengual, Virginia M Picke. Regional and subcellular compartmentation of the dopamine transporter and tyrosine hydroxylase in the rat ventral pallidum. The Journal of comparative neurology. vol 468. issue 3. 2004-03-26. PMID:14681933. |
the vp catecholaminergic innervation is derived from midbrain dopaminergic neurons that differ in expression levels of the dopamine transporter (dat) and from brainstem noradrenergic neurons without dat. |
2004-03-26 |
2023-08-12 |
rat |
| Paola Devoto, Giovanna Flore, Luigi Pira, Giorgio Longu, Gian Luigi Gess. Alpha2-adrenoceptor mediated co-release of dopamine and noradrenaline from noradrenergic neurons in the cerebral cortex. Journal of neurochemistry. vol 88. issue 4. 2004-03-15. PMID:14756822. |
alpha2-adrenoceptor mediated co-release of dopamine and noradrenaline from noradrenergic neurons in the cerebral cortex. |
2004-03-15 |
2023-08-12 |
rat |
| Paola Devoto, Giovanna Flore, Luigi Pira, Giorgio Longu, Gian Luigi Gess. Alpha2-adrenoceptor mediated co-release of dopamine and noradrenaline from noradrenergic neurons in the cerebral cortex. Journal of neurochemistry. vol 88. issue 4. 2004-03-15. PMID:14756822. |
previous results suggest that extracellular dopamine (da) in the rat cerebral cortex originates from dopaminergic and noradrenergic terminals. |
2004-03-15 |
2023-08-12 |
rat |
| Jennifer L Rychlik, Vincent Gerbasi, Elaine J Lewi. The interaction between dHAND and Arix at the dopamine beta-hydroxylase promoter region is independent of direct dHAND binding to DNA. The Journal of biological chemistry. vol 278. issue 49. 2004-03-10. PMID:14506227. |
dopamine beta-hydroxylase (dbh) catalyzes the production of norepinephrine, and its expression defines the noradrenergic phenotype. |
2004-03-10 |
2023-08-12 |
Not clear |
| Louk J M J Vanderschuren, Patricia Beemster, Anton N M Schoffelmee. On the role of noradrenaline in psychostimulant-induced psychomotor activity and sensitization. Psychopharmacology. vol 169. issue 2. 2004-02-10. PMID:12768274. |
however, despite the fact that brain dopamine and noradrenaline systems are closely interconnected, the extent to which noradrenergic transmission contributes to these behavioral effects of psychostimulants is a relatively unexplored issue. |
2004-02-10 |
2023-08-12 |
Not clear |
| Gorazd Bunc, Srecko Kovacic, Simona Strna. The influence of noradrenergic blockade on vasospasm and the quantity of cerebral dopamine beta-hydroxylase following subarachnoid haemorrhage in rabbits. Wiener klinische Wochenschrift. vol 115. issue 17-18. 2004-01-30. PMID:14603737. |
the influence of noradrenergic blockade on vasospasm and the quantity of cerebral dopamine beta-hydroxylase following subarachnoid haemorrhage in rabbits. |
2004-01-30 |
2023-08-12 |
Not clear |
| William A Wol. SLV-308. Solvay. Current opinion in investigational drugs (London, England : 2000). vol 4. issue 7. 2004-01-22. PMID:14619412. |
solvay is developing slv-308 (sme-308), a partial dopamine d2 agonist and noradrenergic agonist with serotonin 5-ht1a agonist properties, for the potential oral treatment of parkinson's disease (pd), panic and depression. |
2004-01-22 |
2023-08-12 |
Not clear |
| Paola Devoto, Giovanna Flore, Giorgio Longu, Luigi Pira, Gian Luigi Gess. Origin of extracellular dopamine from dopamine and noradrenaline neurons in the medial prefrontal and occipital cortex. Synapse (New York, N.Y.). vol 50. issue 3. 2004-01-06. PMID:14515337. |
our recent studies suggest that extracellular dopamine (da) in the cerebral cortex not only originates from dopaminergic terminals but is also coreleased with noradrenaline (na) from noradrenergic terminals [devoto et al. |
2004-01-06 |
2023-08-12 |
Not clear |
| Sueli Pompolo, Alda Pereira, Christopher James Scott, Fumino Fujiyma, Iain James Clark. Evidence for estrogenic regulation of gonadotropin-releasing hormone neurons by glutamatergic neurons in the ewe brain: An immunohistochemical study using an antibody against vesicular glutamate transporter-2. The Journal of comparative neurology. vol 465. issue 1. 2003-12-04. PMID:12926021. |
double-labeling of varicosities in the poa showed colocalization of vglut2 in 12.5 +/- 3% of dopamine beta-hydroxylase-immunoreactive terminals, indicating that a subset of glutamatergic inputs could arise from brainstem noradrenergic neurons cells. |
2003-12-04 |
2023-08-12 |
Not clear |
| Linda Rinama. Hindbrain noradrenergic lesions attenuate anorexia and alter central cFos expression in rats after gastric viscerosensory stimulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 31. 2003-12-02. PMID:14602823. |
in the present study, noradrenergic (na) neurons [i.e., those that express the na synthetic enzyme dopamine beta hydroxylase (dbh)] in the caudal nst were lesioned to determine their role in mediating anorexic responses to gastric stimulation and in conveying gastric sensory signals to the hypothalamus and amygdala. |
2003-12-02 |
2023-08-12 |
human |
| David S Goldstei. Dysautonomia in Parkinson's disease: neurocardiological abnormalities. The Lancet. Neurology. vol 2. issue 11. 2003-12-01. PMID:14572735. |
because pd involves postganglionic sympathetic noradrenergic lesions, the disease seems to be not only a movement disorder with dopamine loss in the nigrostriatal system of the brain, but also a dysautonomia, with norepinephrine loss in the sympathetic nervous system of the heart. |
2003-12-01 |
2023-08-12 |
Not clear |
| Giovanni Cucchiaro, Kathryn G Common. Alpha 4 nicotinic acetylcholine receptor subunit links cholinergic to brainstem monoaminergic neurotransmission. Synapse (New York, N.Y.). vol 49. issue 3. 2003-10-07. PMID:12774304. |
however, it was also noted that alpha4 was present in all other brainstem monoaminergic nuclei examined (adrenergic c1-c3, noradrenergic a1-alpha4, dopamine a9 and a10, nucleus raphe medianus). |
2003-10-07 |
2023-08-12 |
Not clear |
| Paola Devoto, Giovanna Flore, Giada Vacca, Luigi Pira, Alessandra Arca, Maria Antonietta Casu, Luca Pani, Gian Luigi Gess. Co-release of noradrenaline and dopamine from noradrenergic neurons in the cerebral cortex induced by clozapine, the prototype atypical antipsychotic. Psychopharmacology. vol 167. issue 1. 2003-08-22. PMID:12632247. |
co-release of noradrenaline and dopamine from noradrenergic neurons in the cerebral cortex induced by clozapine, the prototype atypical antipsychotic. |
2003-08-22 |
2023-08-12 |
Not clear |
| S Pompolo, A Pereira, T Kaneko, I J Clark. Seasonal changes in the inputs to gonadotropin-releasing hormone neurones in the ewe brain: an assessment by conventional fluorescence and confocal microscopy. Journal of neuroendocrinology. vol 15. issue 5. 2003-08-07. PMID:12694380. |
using double-labelling immunohistochemistry, we counted close appositions between gnrh cells and varicosities that were immunoreactive for either glutamic acid decarboxylase (gad; for gamma-amino butyric acid-gaba-neurones), dopamine beta hydroxylase (dbh; for noradrenergic neurones), vesicular glutamate transporter-1 (vglut-1, for glutamatergic neurones), neuropeptide y (npy) and tyrosine hydroxylase (th; for dopaminergic/noradrenergic neurones). |
2003-08-07 |
2023-08-12 |
Not clear |
| Gorazd Bunc, Srecko Kovacic, Simona Strna. Attenuation of cerebral vasospasm in rabbits using clonidine hydrochloride, a central adrenergic agonist. Autonomic neuroscience : basic & clinical. vol 105. issue 1. 2003-07-24. PMID:12742193. |
the aim of this study was to assess, firstly, if exclusion of central noradrenergic areas in the hypothalamus and brain stem with the central sympathetic blocker clonidine hydrochloride could prevent the development of chronic vasospasm following experimental subarachnoid haemorrhage in rabbits and, secondly, if, parallel with the effect on cerebral arteries, changes in dopamine beta-hydroxylase concentration in the hypothalamus and brain stem could also be detected. |
2003-07-24 |
2023-08-12 |
rabbit |
| Ruey-Ming Liao, Wen-Sung Lai, Jian-You Li. The role of catecholamines in retention performance of a partially baited radial eight-arm maze for rats. The Chinese journal of physiology. vol 45. issue 4. 2003-07-21. PMID:12817709. |
evidently, both d1 and d2 dopamine receptors as well as beta noradrenergic receptors are important in expression of spatial memory. |
2003-07-21 |
2023-08-12 |
human |
| M L Rao, H Kölsc. Effects of estrogen on brain development and neuroprotection--implications for negative symptoms in schizophrenia. Psychoneuroendocrinology. vol 28 Suppl 2. 2003-06-18. PMID:12650683. |
measures of noradrenergic activity, dopamine beta-hydroxylase and the metabolite mhpg, appear to decrease with brain atrophy seen in patients with negative symptoms. |
2003-06-18 |
2023-08-12 |
Not clear |
| Alan I Green, Melinda S Salomon, Mark J Brenner, Kimberly Rawlin. Treatment of schizophrenia and comorbid substance use disorder. Current drug targets. CNS and neurological disorders. vol 1. issue 2. 2003-06-18. PMID:12769622. |
we have proposed that the effect of clozapine in this population may relate to its broad pharmacological effects, including its relatively weak blockade of the dopamine d2 receptor and its potent blockade of the serotonergic 5-ht2 receptor and the noradrenergic alpha 1 and alpha 2 receptors. |
2003-06-18 |
2023-08-12 |
Not clear |
| Kwang-Soo Kim, Chun-Hyung Kim, Dong-Youn Hwang, Hyemyung Seo, Sangmi Chung, Seok Jong Hong, Jin-Kyu Lim, Therese Anderson, Ole Isacso. Orphan nuclear receptor Nurr1 directly transactivates the promoter activity of the tyrosine hydroxylase gene in a cell-specific manner. Journal of neurochemistry. vol 85. issue 3. 2003-06-17. PMID:12694388. |
tyrosine hydroxylase (th) catalyzes the first and rate-limiting step of catecholamine synthesis and its expression is necessary for neurotransmitter specification of all catecholaminergic neurons, while dopamine beta-hydroxylase (dbh) is essential for the noradrenergic phenotype. |
2003-06-17 |
2023-08-12 |
Not clear |