| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R A Wise, M A Bozart. Action of drugs of abuse on brain reward systems: an update with specific attention to opiates. Pharmacology, biochemistry, and behavior. vol 17. issue 2. 1982-12-16. PMID:6127721. |
recent evidence indicates that the rewarding action of opiates is mediated in the region of the dopaminergic cells of the ventral tegmentum and not in the region of the noradrenergic cells of locus coeruleus. |
1982-12-16 |
2023-08-12 |
Not clear |
| A L Acheson, M J Zigmon. Short and long term changes in tyrosine hydroxylase activity in rat brain after subtotal destruction of central noradrenergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 1. issue 5. 1982-10-29. PMID:6125573. |
this increase was preceded by a 2-fold rise in the amount of enzyme present in the region of the locus coeruleus, an area rich in noradrenergic cell bodies. |
1982-10-29 |
2023-08-12 |
rat |
| J J Scuvée-Moreau, T H Svensso. Sensitivity in vivo of central alpha 2- and opiate receptors after chronic treatment with various antidepressants. Journal of neural transmission. vol 54. issue 1-2. 1982-10-29. PMID:6286872. |
in view of the important role of these receptors in the regulation of noradrenergic neuro-transmission, single cell recording and microiontophoretic techniques were used in this work to systematically assess locus coeruleus (l.c.) |
1982-10-29 |
2023-08-12 |
Not clear |
| S I Harik, R B Duckrow, J C LaManna, M Rosenthal, V K Sharma, S P Banerje. Cerebral compensation for chronic noradrenergic denervation induced by locus ceruleus lesion: recovery of receptor binding, isoproterenol-induced adenylate cyclase activity, and oxidative metabolism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 1. issue 6. 1982-10-29. PMID:7346572. |
cerebral compensation for chronic noradrenergic denervation induced by locus ceruleus lesion: recovery of receptor binding, isoproterenol-induced adenylate cyclase activity, and oxidative metabolism. |
1982-10-29 |
2023-08-12 |
rat |
| S I Harik, R B Duckrow, J C LaManna, M Rosenthal, V K Sharma, S P Banerje. Cerebral compensation for chronic noradrenergic denervation induced by locus ceruleus lesion: recovery of receptor binding, isoproterenol-induced adenylate cyclase activity, and oxidative metabolism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 1. issue 6. 1982-10-29. PMID:7346572. |
noradrenergic denervation was achieved by the local, unilateral injection of 6-hydroxydopamine into the locus ceruleus. |
1982-10-29 |
2023-08-12 |
rat |
| J P Boulenger, T W Uhd. Biological peripheral correlates of anxiety. L'Encephale. vol 8. issue 2. 1982-10-21. PMID:7106044. |
redmond (1979) has proposed a model for the study of anxiety based upon the function of the noradrenergic locus coeruleus (lc) which may provide a neuroanatomical basis for these changes. |
1982-10-21 |
2023-08-12 |
human |
| N Quinaux, J Scuvée-Moreau, A Dress. Inhibition of in vitro and ex vivo uptake of noradrenaline and 5-hydroxytryptamine by five antidepressants; correlation with reduction of spontaneous firing rate of central monoaminergic neurones. Naunyn-Schmiedeberg's archives of pharmacology. vol 319. issue 1. 1982-10-12. PMID:7110371. |
electrophysiological studies show that these drugs also decrease the firing rate of the noradrenergic neurones of the locus coeruleus (l.c.) |
1982-10-12 |
2023-08-12 |
Not clear |
| S Nakamura, J M Tepper, S J Young, N Ling, P M Grove. Noradrenergic terminal excitability: effects of opioids. Neuroscience letters. vol 30. issue 1. 1982-09-24. PMID:6124916. |
the local infusion of morphine or d-ala2, met5-enkephalinamide into the frontal cortical terminal fields of noradrenergic neurons of the nucleus locus coeruleus resulted in a decrease in the excitability of the axon terminal regions to direct electrical stimulation. |
1982-09-24 |
2023-08-12 |
Not clear |
| M H Millan, M J Millan, A Her. Selective destruction of the ventral noradrenergic bundle but not of the locus coeruleus elevates plasma levels of beta-endorphin immunoreactivity in rats. Neuroscience letters. vol 29. issue 3. 1982-09-24. PMID:6285231. |
selective destruction of the ventral noradrenergic bundle but not of the locus coeruleus elevates plasma levels of beta-endorphin immunoreactivity in rats. |
1982-09-24 |
2023-08-12 |
rat |
| M H Millan, M J Millan, A Her. Selective destruction of the ventral noradrenergic bundle but not of the locus coeruleus elevates plasma levels of beta-endorphin immunoreactivity in rats. Neuroscience letters. vol 29. issue 3. 1982-09-24. PMID:6285231. |
lesions of the locus coeruleus, the primary origin of the dorsal noradrenergic bundle, in contrast, decreased na levels in the cortex but not the hypothalamus and failed to modify beta-ei levels in plasma. |
1982-09-24 |
2023-08-12 |
rat |
| B E Levi. Presynaptic location and axonal transport of beta 1-adrenoreceptors in the rat brain. Science (New York, N.Y.). vol 217. issue 4559. 1982-08-26. PMID:6178165. |
interruption of the ascending noradrenergic neurons of the locus coeruleus in the rat forebrain with 6-hydroxydopamine produced a progressive accumulation, proximal to the lesion, of tritiated dihydroalprenolol binding activity over 2 days. |
1982-08-26 |
2023-08-12 |
rat |
| B E Levi. Presynaptic location and axonal transport of beta 1-adrenoreceptors in the rat brain. Science (New York, N.Y.). vol 217. issue 4559. 1982-08-26. PMID:6178165. |
these results suggest that, in the rat brain, some beta 1-adrenoreceptors are located in presynaptic, noradrenergic locus coeruleus neurons and are transported in their axons. |
1982-08-26 |
2023-08-12 |
rat |
| G K Aghajania. Central noradrenergic neurons: a locus for the functional interplay between alpha-2 adrenoceptors and opiate receptors. The Journal of clinical psychiatry. vol 43. issue 6 Pt 2. 1982-08-07. PMID:6282816. |
the locus coeruleus (lc) contains the largest clusters of noradrenergic neurons in the brain. |
1982-08-07 |
2023-08-12 |
human |
| D E Redmond, Y H Huan. The primate locus coeruleus and effects of clonidine on opiate withdrawal. The Journal of clinical psychiatry. vol 43. issue 6 Pt 2. 1982-08-07. PMID:6282817. |
studies of nonhuman primates suggested that the noradrenergic locus coeruleus (lc) may be involved as part of the neural substrate for a brain alarm function which includes attentiveness, arousal, anxiety, fear, terror, and the physiological correlates of these states. |
1982-08-07 |
2023-08-12 |
human |
| A Janowsky, L R Steranka, D D Gillespie, F Sulse. Role of neuronal signal input in the down-regulation of central noradrenergic receptor function by antidepressant drugs. Journal of neurochemistry. vol 39. issue 1. 1982-08-07. PMID:6283020. |
rats with unilateral lesions of the locus coeruleus were used to study the role of norepinephrine (ne) signal input in the down-regulation by antidepressants of the noradrenergic cyclic amp-generating system in the cortex. |
1982-08-07 |
2023-08-12 |
rat |
| G Waddington, A J Bower, P Bank. The effects of neonatal pedunclectomy on [3H]noradrenaline uptake and the development of beta-adrenergic receptors in the rat cerebellum. Journal of neurochemistry. vol 38. issue 6. 1982-07-22. PMID:6281385. |
it is suggested that the remaining high-affinity noradrenaline uptake cannot be attributed to noradrenergic fibres from the locus coeruleus. |
1982-07-22 |
2023-08-12 |
rat |
| E Ben-Menachem, B B Johansson, T H Svensso. Increased vulnerability of the blood-brain barrier to acute hypertension following depletion of brain noradrenaline. Journal of neural transmission. vol 53. issue 2-3. 1982-07-19. PMID:6804601. |
noradrenergic nerve terminals emanating from the pontine nucleus locus coeruleus (lc) have been suggested to take part in the regulation of intracerebral microvascular tone and, hence, blood flow. |
1982-07-19 |
2023-08-12 |
rat |
| B Berger, U Di Porzio, M C Daguet, M Gay, A Vigny, J Glowinski, A Prochiant. Long-term development of mesencephalic dopaminergic neurons of mouse embryos in dissociated primary cultures: morphological and histochemical characteristics. Neuroscience. vol 7. issue 1. 1982-07-08. PMID:6123092. |
at this time, noradrenergic cells in the locus coeruleus area were not detectable. |
1982-07-08 |
2023-08-12 |
mouse |
| Y Kayama, T Negi, M Sugitani, K Iwam. Effects of locus coeruleus stimulation on neuronal activities of dorsal lateral geniculate nucleus and perigeniculate reticular nucleus of the rat. Neuroscience. vol 7. issue 3. 1982-06-24. PMID:6280101. |
in rats anesthetized with urethane, a stimulating electrode was introduced to the locus coeruleus by observing the antidromic field response to single shock stimulation of the dorsal pathway of noradrenergic axons. |
1982-06-24 |
2023-08-12 |
rat |
| C W Scouten, C W Harley, C W Malsbur. Labeling knife cuts: a new method for revealing the functional anatomy of the CNS demonstrated on the noradrenergic dorsal bundle. Brain research bulletin. vol 8. issue 2. 1982-06-14. PMID:7066710. |
the noradrenergic axons in the dorsal bundle arise from cells in the locus coeruleus. |
1982-06-14 |
2023-08-12 |
Not clear |