| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G K Aghajanian, C P VanderMaele. alpha 2-adrenoceptor-mediated hyperpolarization of locus coeruleus neurons: intracellular studies in vivo. Science (New York, N.Y.). vol 215. issue 4538. 1982-05-27. PMID:6278591. |
intracellular recordings in vivo from noradrenergic neurons in the rat locus coeruleus showed that membrane potential was hyperpolarized by the administration of clonidine (an alpha 2-adrenoceptor agonist) or after a burst of spikes evoked by intracellular pulses; both types of hyperpolarization were associated with a decrease in membrane input resistance, and both could be blocked by the alpha 2-adrenoceptor antagonist piperoxane. |
1982-05-27 |
2023-08-12 |
rat |
| W J Logan, S I Hari. Specific uptake of norepinephrine and dopamine by homogenates of rat cerebral cortex after locus ceruleus lesion. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 3. 1982-05-27. PMID:7062118. |
two and 8 weeks after locus ceruleus lesion, a dmi-insensitive, benztropine-sensitive dopamine uptake becomes apparent in ipsilateral cortical preparations, this may represent proliferation or increased function of dopaminergic cortical projections, compensating for noradrenergic denervation. |
1982-05-27 |
2023-08-12 |
rat |
| S J Grant, D E Redmon. The neuroanatomy and pharmacology of the nucleus locus coeruleus. Progress in clinical and biological research. vol 71. 1982-04-22. PMID:6276901. |
although these changes affect numerous types of behavior and responses that are measurable by psychopharmacologists, it is the neurons of the locus coeruleus and other noradrenergic neurons with similar receptor combination that provide the entry point to this ne system. |
1982-04-22 |
2023-08-12 |
Not clear |
| B Ghetti, R W Fuller, B D Sawyer, S K Hemrick-Luecke, M J Schmid. Purkinje cell loss and the noradrenergic system in the cerebellum of pcd mutant mice. Brain research bulletin. vol 7. issue 6. 1982-04-12. PMID:7326585. |
purkinje cells in the cerebellum receive inhibitory noradrenergic input from the locus coeruleus. |
1982-04-12 |
2023-08-12 |
mouse |
| L Yurkewicz, M Marchi, J M Lauder, E Giacobin. Development and aging of noradrenergic cell bodies and axon terminals in the chicken. Journal of neuroscience research. vol 6. issue 5. 1982-03-22. PMID:6119368. |
tyrosine hydroxylase activity was measured in the region of locus coeruleus, cerebellum, cervical spinal cord, lumbar sympathetic ganglia, and iris throughout most of the life span of the chicken (8 days of incubation to 5 years) to compare developmental trends in tyrosine hydroxylase activity in noradrenergic cell bodies and in axon terminals in both the central and peripheral nervous system. |
1982-03-22 |
2023-08-12 |
chicken |
| W Bondareff, C Q Mountjoy, M Rot. Loss of neurons of origin of the adrenergic projection to cerebral cortex (nucleus locus ceruleus) in senile dementia. Neurology. vol 32. issue 2. 1982-03-22. PMID:7198741. |
to examine the possibility that senile dementia may be associated with a loss of noradrenergic neurons that innervate the cerebral cortex, we used a quantimet 720 image analyzer to estimate the number of neurons in the nucleus locus ceruleus in elderly patients with the clinical diagnosis of senile dementia. |
1982-03-22 |
2023-08-12 |
Not clear |
| Y H Huang, J W Maa. D-Amphetamine at low doses suppresses noradrenergic functions. European journal of pharmacology. vol 75. issue 4. 1982-03-22. PMID:7318907. |
this study examined the effects of d-amphetamine on the firing rate of hippocampal cells which had been shown to have an inhibitory, noradrenergic input from the nucleus locus coeruleus (lc). |
1982-03-22 |
2023-08-12 |
Not clear |
| Y Osumi, T Ishikawa, Y Okuma, Y Nagasaka, M Fujiwar. Inhibition of gastric functions by stimulation of rat locus coeruleus. European journal of pharmacology. vol 75. issue 1. 1982-03-13. PMID:7318897. |
to investigate the possible role of central noradrenergic neurons in the regulation of gastric functions, electrical stimulation of the locus coeruleus [lc] and microinjection of noradrenaline [na] into the ala cinerea (area of the dorsal motor nucleus of the vagi [ndv] and the nucleus tractus solitarius [nts]) were given to urethane-anesthetized rats. |
1982-03-13 |
2023-08-12 |
rat |
| H R Olpe, M W Steinman. Rapid communication the activating activity of vincamine, piracetam, and hydergine on the activity of the noradrenergic neurons of the locus coeruleus. Behavioral and neural biology. vol 33. issue 2. 1982-01-20. PMID:7305817. |
rapid communication the activating activity of vincamine, piracetam, and hydergine on the activity of the noradrenergic neurons of the locus coeruleus. |
1982-01-20 |
2023-08-12 |
Not clear |
| P Levitt, J L Noebel. Mutant mouse tottering: selective increase of locus ceruleus axons in a defined single-locus mutation. Proceedings of the National Academy of Sciences of the United States of America. vol 78. issue 7. 1981-12-21. PMID:6945603. |
histochemical analysis showed a significant increase in the number of noradrenergic axons in terminal fields innervated by the nucleus locus ceruleus when compared with the wild type. |
1981-12-21 |
2023-08-12 |
mouse |
| A F Arnsten, D S Segal, S E Loughlin, D C Robert. Evidence for an interaction of opioid and noradrenergic locus coeruleus systems in the regulation of environmental stimulus-directed behavior. Brain research. vol 222. issue 2. 1981-12-21. PMID:7284783. |
evidence for an interaction of opioid and noradrenergic locus coeruleus systems in the regulation of environmental stimulus-directed behavior. |
1981-12-21 |
2023-08-12 |
rat |
| G Engberg, M Elam, T H Svensso. Effect of adrenaline synthesis inhibition on brain noradrenaline neurons in locus coeruleus. Brain research. vol 223. issue 1. 1981-12-15. PMID:7284809. |
the functional significance of the morphologically identified adrenaline (a)-mediated input to the noradrenergic nucleus locus coeruleus (lc) was pharmacologically analyzed. |
1981-12-15 |
2023-08-12 |
rat |
| P E Sawchenko, L W Swanso. Central noradrenergic pathways for the integration of hypothalamic neuroendocrine and autonomic responses. Science (New York, N.Y.). vol 214. issue 4521. 1981-12-15. PMID:7292008. |
the results indicate that pathways arising from noradrenergic cells in the dorsal vagal complex, the ventrolateral medulla, and the locus coeruleus end in specific subdivisions of the paraventricular and supraoptic nuclei which are involved in the regulation of responses from the pituitary gland and from both divisions of the autonomic nervous system. |
1981-12-15 |
2023-08-12 |
Not clear |
| E K Perry, B E Tomlinson, G Blessed, R H Perry, A J Cross, T J Cro. Neuropathological and biochemical observations on the noradrenergic system in Alzheimer's disease. Journal of the neurological sciences. vol 51. issue 2. 1981-11-22. PMID:7276979. |
abnormalities of the noradrenergic system in alzheimer's disease have been investigated by comparing quantitative histological and biochemical components of this transmitter system (locus coeruleus neuron counts and cortical dopamine beta-hydroxylase (dbh) activity, respectively) in a series of demented and non-demented cases. |
1981-11-22 |
2023-08-12 |
Not clear |
| E K Perry, B E Tomlinson, G Blessed, R H Perry, A J Cross, T J Cro. Neuropathological and biochemical observations on the noradrenergic system in Alzheimer's disease. Journal of the neurological sciences. vol 51. issue 2. 1981-11-22. PMID:7276979. |
cortical activities of the noradrenergic enzyme, dbh, did not correlate significantly with the number of locus coeruleus neurons, a finding which contrasts with the previous observations in animal brains of reductions in cortical dbh following locus coeruleus lesions. |
1981-11-22 |
2023-08-12 |
Not clear |
| C Dahlöf, G Engberg, T H Svensso. Effects of beta-adrenoceptor antagonists on the firing rate of noradrenergic neurones in the locus coeruleus of the rat. Naunyn-Schmiedeberg's archives of pharmacology. vol 317. issue 1. 1981-11-18. PMID:6116197. |
effects of beta-adrenoceptor antagonists on the firing rate of noradrenergic neurones in the locus coeruleus of the rat. |
1981-11-18 |
2023-08-12 |
rat |
| P A van Donge. The central noradrenergic transmission and the locus coeruleus: a review of the data, and their implications for neurotransmission and neuromodulation. Progress in neurobiology. vol 16. issue 2. 1981-11-18. PMID:6116259. |
the central noradrenergic transmission and the locus coeruleus: a review of the data, and their implications for neurotransmission and neuromodulation. |
1981-11-18 |
2023-08-12 |
Not clear |
| L Velley, B Cardo, E Kemp. [Improvement of post-training performance 4 weeks after stimulation of the locus coeruleus in rats : absence of an effect of a lesion of the dorsal noradrenergic bundle]. Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie. vol 292. issue 16. 1981-10-25. PMID:6790192. |
[improvement of post-training performance 4 weeks after stimulation of the locus coeruleus in rats : absence of an effect of a lesion of the dorsal noradrenergic bundle]. |
1981-10-25 |
2023-08-12 |
rat |
| L Velley, B Cardo, E Kemp. [Improvement of post-training performance 4 weeks after stimulation of the locus coeruleus in rats : absence of an effect of a lesion of the dorsal noradrenergic bundle]. Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie. vol 292. issue 16. 1981-10-25. PMID:6790192. |
the locus coeruleus stimulation induced nearly the same improvement of performances whether or not the dorsal noradrenergic bundle was lesioned. |
1981-10-25 |
2023-08-12 |
rat |
| D L Felten, J P Cummings, B T Burnet. Ontogeny of caudal fourth ventricular tanycytes in the rabbit brain: a Golgi study. The Anatomical record. vol 200. issue 3. 1981-10-14. PMID:6168213. |
these shafts ended in the serotonergic nuclei raphe obscurus and pallidus, and the noradrenergic locus coeruleus and nucleus intercalatus (group a2). |
1981-10-14 |
2023-08-12 |
rabbit |