| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ling-Xiao Deng, Nai-Kui Liu, Ryan Ning Wen, Shuang-Ni Yang, Xuejun Wen, Xiao-Ming X. Laminin-coated multifilament entubulation, combined with Schwann cells and glial cell line-derived neurotrophic factor, promotes unidirectional axonal regeneration in a rat model of thoracic spinal cord hemisection. Neural regeneration research. vol 16. issue 1. 2021-05-17. PMID:32788475. |
laminin-coated multifilament entubulation, combined with schwann cells and glial cell line-derived neurotrophic factor, promotes unidirectional axonal regeneration in a rat model of thoracic spinal cord hemisection. |
2021-05-17 |
2023-08-13 |
rat |
| Ling-Xiao Deng, Nai-Kui Liu, Ryan Ning Wen, Shuang-Ni Yang, Xuejun Wen, Xiao-Ming X. Laminin-coated multifilament entubulation, combined with Schwann cells and glial cell line-derived neurotrophic factor, promotes unidirectional axonal regeneration in a rat model of thoracic spinal cord hemisection. Neural regeneration research. vol 16. issue 1. 2021-05-17. PMID:32788475. |
in the present study, we evaluated permissive effect of poly (acrylonitrile-co-vinyl chloride) guidance channels filled by different densities of laminin-precoated unidirectional polypropylene filaments combined with schwann cells, and glial cell line-derived neurotrophic factor for axonal regeneration through a t10 hemisected spinal cord gap in adult rats. |
2021-05-17 |
2023-08-13 |
rat |
| Ling-Xiao Deng, Nai-Kui Liu, Ryan Ning Wen, Shuang-Ni Yang, Xuejun Wen, Xiao-Ming X. Laminin-coated multifilament entubulation, combined with Schwann cells and glial cell line-derived neurotrophic factor, promotes unidirectional axonal regeneration in a rat model of thoracic spinal cord hemisection. Neural regeneration research. vol 16. issue 1. 2021-05-17. PMID:32788475. |
these results demonstrate that the combinatorial strategy of filament-filled guiding scaffold, adhesive molecular laminin, schwann cells, and glial cell line-derived neurotrophic factor, provides optimal topographical cues in stimulating directional axonal regeneration following spinal cord injury. |
2021-05-17 |
2023-08-13 |
rat |
| Michela Campolo, Marika Lanza, Irene Paterniti, Alessia Filippone, Alessio Ardizzone, Giovanna Casili, Sarah A Scuderi, Caterina Puglisi, Marzia Mare, Lorenzo Memeo, Salvatore Cuzzocrea, Emanuela Esposit. PEA-OXA Mitigates Oxaliplatin-Induced Painful Neuropathy through NF-κB/Nrf-2 Axis. International journal of molecular sciences. vol 22. issue 8. 2021-05-13. PMID:33920318. |
our results demonstrated that pea-oxa, more than peaum, reduced the development of hypersensitivity in rats; this was associated with the reduction in hyperactivation of glia cells and the increased production of proinflammatory cytokines in the dorsal horn of the spinal cord, accompanied by an upregulation of neurotrophic factors in the dorsal root ganglia (drg). |
2021-05-13 |
2023-08-13 |
rat |
| Shanglin Li, Yicheng Zhu, Ming Ya. Spinal Cord Involvement in Adult-Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia. JAMA neurology. vol 77. issue 9. 2021-03-31. PMID:32658280. |
spinal cord involvement in adult-onset leukoencephalopathy with axonal spheroids and pigmented glia. |
2021-03-31 |
2023-08-13 |
Not clear |
| The people behind the papers - Kayt Scott and Bruce Appel. Development (Cambridge, England). vol 147. issue 16. 2021-03-23. PMID:32855203. |
in the developing spinal cord, progenitor cells sequentially give rise to motor neurons and precursors of one of the major glial cell types: oligodendrocytes. |
2021-03-23 |
2023-08-13 |
zebrafish |
| Julio C Furlan, Yang Liu, W Dalton Dietrich, Michael D Norenberg, Michael G Fehling. Age as a determinant of inflammatory response and survival of glia and axons after human traumatic spinal cord injury. Experimental neurology. vol 332. 2021-03-09. PMID:32673621. |
age as a determinant of inflammatory response and survival of glia and axons after human traumatic spinal cord injury. |
2021-03-09 |
2023-08-13 |
human |
| Carmen Muñoz-Ballester, Robyn A Umans, Stefanie Robe. Leveraging Zebrafish To Study Bona Fide Astrocytes. Trends in neurosciences. vol 44. issue 2. 2021-03-01. PMID:33213859. |
in a recent study, chen and colleagues demonstrated that zebrafish spinal cord radial glia differentiate into cells that are similar to mammalian astrocytes. |
2021-03-01 |
2023-08-13 |
zebrafish |
| Sanjay Kumar, Manjula Vinaya. NADPH oxidase1 inhibition leads to regression of central sensitization during formalin induced acute nociception via attenuation of ERK1/2-NFκB signaling and glial activation. Neurochemistry international. vol 134. 2021-02-23. PMID:31891736. |
thus, the present study was focused to investigate the effect of ml171 on erk1/2 signaling, glial activation, and crosstalk between neuron and glia in drg and dorsal horn of the spinal cord of lumbar region (l3-l5) in a mouse model of formalin induced acute nociception. |
2021-02-23 |
2023-08-13 |
mouse |
| Sanjay Kumar, Manjula Vinaya. NADPH oxidase1 inhibition leads to regression of central sensitization during formalin induced acute nociception via attenuation of ERK1/2-NFκB signaling and glial activation. Neurochemistry international. vol 134. 2021-02-23. PMID:31891736. |
erk1/2 was found to be activated in glia and nfκb in neurons in drg; whereas in case of spinal cord erk1/2 was activated in neurons and nfκb in astrocytes. |
2021-02-23 |
2023-08-13 |
mouse |
| Laura Fontenas, Sarah Kucena. Spinal cord precursors utilize neural crest cell mechanisms to generate hybrid peripheral myelinating glia. eLife. vol 10. 2021-02-20. PMID:33554855. |
spinal cord precursors utilize neural crest cell mechanisms to generate hybrid peripheral myelinating glia. |
2021-02-20 |
2023-08-13 |
zebrafish |
| Sajad Hassanzadeh, Maryam Jalessi, Seyed Behnamedin Jameie, Mehdi Khanmohammadi, Zohre Bagher, Zeinab Namjoo, Seyed Mohammad Davach. More attention on glial cells to have better recovery after spinal cord injury. Biochemistry and biophysics reports. vol 25. 2021-02-10. PMID:33553683. |
here, we first scrutinize recent findings on glial cell subtypes and their beneficial or detrimental effects after spinal cord injury. |
2021-02-10 |
2023-08-13 |
Not clear |
| Simon J O'Carroll, William H Cook, Deborah Youn. AAV Targeting of Glial Cell Types in the Central and Peripheral Nervous System and Relevance to Human Gene Therapy. Frontiers in molecular neuroscience. vol 13. 2021-01-30. PMID:33505247. |
these cell types are also involved in nervous system pathology, playing roles in neurodegenerative disease and following trauma in the brain and spinal cord (astrocytes, microglia, oligodendrocytes), nerve degeneration and development of pain in peripheral nerves (schwann cells, satellite cells), retinal diseases (müller glia) and gut dysbiosis (enteric glia). |
2021-01-30 |
2023-08-13 |
human |
| Michael J Rigby, Timothy M Gomez, Luigi Pugliell. Glial Cell-Axonal Growth Cone Interactions in Neurodevelopment and Regeneration. Frontiers in neuroscience. vol 14. 2021-01-26. PMID:32210757. |
this focus will be applied to the clinically-relevant field of regeneration following spinal cord injury, highlighting how a better understanding of the roles of glia in neurodevelopment can inform strategies to improve axon regeneration after injury. |
2021-01-26 |
2023-08-13 |
Not clear |
| Samar S Elblehi, Omnia I El Euony, Yasser S El-Saye. Apoptosis and astrogliosis perturbations and expression of regulatory inflammatory factors and neurotransmitters in acrylamide-induced neurotoxicity under ω3 fatty acids protection in rats. Neurotoxicology. vol 76. 2021-01-20. PMID:31647937. |
histopathologically, acr caused various degenerative changes, necrosis and glial cell activation in the cerebrum, cerebellum, hippocampus, spinal cord and sciatic nerve. |
2021-01-20 |
2023-08-13 |
rat |
| Ronak Reshamwala, Megha Shah, Lucy Belt, Jenny A K Ekberg, James A St Joh. Reliable cell purification and determination of cell purity: crucial aspects of olfactory ensheathing cell transplantation for spinal cord repair. Neural regeneration research. vol 15. issue 11. 2020-12-11. PMID:32394949. |
transplantation of olfactory ensheathing cells, the glia of the primary olfactory nervous system, has been trialed for spinal cord injury repair with promising but variable outcomes in animals and humans. |
2020-12-11 |
2023-08-13 |
Not clear |
| Laureen D Hachem, Andrea J Mothe, Charles H Tato. Unlocking the paradoxical endogenous stem cell response after spinal cord injury. Stem cells (Dayton, Ohio). vol 38. issue 2. 2020-12-04. PMID:31648407. |
nearly a century ago, the concept of the secondary injury in spinal cord trauma was first proposed to explain the complex cascade of molecular and cellular events leading to widespread neuronal and glial cell death after trauma. |
2020-12-04 |
2023-08-13 |
Not clear |
| Jennifer H LaVai. A Model of In Vivo HSV-1 DNA Transport Using Murine Retinal Ganglion Cells. Methods in molecular biology (Clifton, N.J.). vol 2060. 2020-12-01. PMID:31617195. |
the retina, brain, spinal cord, and peripheral sensory and autonomic ganglia are each composed of neuronal and glial cell partners embedded in a connective tissue bed and supplied by vascular and immune cells. |
2020-12-01 |
2023-08-13 |
mouse |
| Christopher G Hart, Scott M Dyck, Hardeep Kataria, Arsalan Alizadeh, Pandian Nagakannan, James A Thliveris, Eftekhar Eftekharpour, Soheila Karimi-Abdolrezae. Acute upregulation of bone morphogenetic protein-4 regulates endogenous cell response and promotes cell death in spinal cord injury. Experimental neurology. vol 325. 2020-10-23. PMID:31881217. |
traumatic spinal cord injury (sci) elicits a cascade of secondary injury mechanisms that induce profound changes in glia and neurons resulting in their activation, injury or cell death. |
2020-10-23 |
2023-08-13 |
rat |
| Maria Domenica Sanna, Vittoria Borgonetti, Nicoletta Galeott. μ Opioid Receptor-Triggered Notch-1 Activation Contributes to Morphine Tolerance: Role of Neuron-Glia Communication. Molecular neurobiology. vol 57. issue 1. 2020-10-07. PMID:31347026. |
spinal cord glial cell activation appears to play a pivotal role in the development and maintenance of opioid tolerance, indicating the presence of an opioid-induced neuronal-glial interaction; however, how opioids drive this cross-talk is still elusive. |
2020-10-07 |
2023-08-13 |
mouse |