Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Junjie Sun, Yixing Song, Zhiheng Chen, Jiaying Qiu, Shunxing Zhu, Liucheng Wu, Lingyan Xin. Heterogeneity and Molecular Markers for CNS Glial Cells Revealed by Single-Cell Transcriptomics. Cellular and molecular neurobiology. 2021-10-27. PMID:34704168. |
this review summarizes the marker genes of major glial cells in the cns and reveals their heterogeneity in different species, cns regions, developmental stages, and pathological states (alzheimer's disease and spinal cord injury), expanding our knowledge of glial cell heterogeneity on both molecular and functional levels. |
2021-10-27 |
2023-08-13 |
Not clear |
Rebecca San Gil, Benjamin E Clarke, Heath Ecroyd, Bernadett Kalmar, Linda Greensmit. Regional Differences in Heat Shock Protein 25 Expression in Brain and Spinal Cord Astrocytes of Wild-Type and SOD1 Cells. vol 10. issue 5. 2021-10-25. PMID:34069691. |
regional differences in heat shock protein 25 expression in brain and spinal cord astrocytes of wild-type and sod1 heterogeneity of glia in different cns regions may contribute to the selective vulnerability of neuronal populations in neurodegenerative conditions such as amyotrophic lateral sclerosis (als). |
2021-10-25 |
2023-08-13 |
Not clear |
Rebecca San Gil, Benjamin E Clarke, Heath Ecroyd, Bernadett Kalmar, Linda Greensmit. Regional Differences in Heat Shock Protein 25 Expression in Brain and Spinal Cord Astrocytes of Wild-Type and SOD1 Cells. vol 10. issue 5. 2021-10-25. PMID:34069691. |
to explore the physiological role of the elevated hsp25 expression in spinal cord astrocytes, we exposed cortical and spinal cord glia to acute stress, using heat stress and pro-inflammatory stimuli. |
2021-10-25 |
2023-08-13 |
Not clear |
Mawj Mandwie, Jordan A Piper, Catherine A Gorrie, Kevin A Keay, Giuseppe Musumeci, Ghaith Al-Badri, Alessandro Castorin. Rapid GFAP and Iba1 expression changes in the female rat brain following spinal cord injury. Neural regeneration research. vol 17. issue 2. 2021-10-22. PMID:34269213. |
evidence suggests that rapid changes to supporting glia may predispose individuals with spinal cord injury (sci) to such comorbidities. |
2021-10-22 |
2023-08-13 |
rat |
Subhra Prakash Hui, Tapas Chandra Nag, Sukla Ghos. Neural cells and their progenitors in regenerating zebrafish spinal cord. The International journal of developmental biology. vol 64. issue 4-5-6. 2021-10-14. PMID:32658995. |
in contrast to mammals, the adult zebrafish is capable of regenerating damaged axonal tracts; it can replace neurons and glia lost after spinal cord injury (sci) and functionally recover. |
2021-10-14 |
2023-08-13 |
zebrafish |
Subhra Prakash Hui, Tapas Chandra Nag, Sukla Ghos. Neural cells and their progenitors in regenerating zebrafish spinal cord. The International journal of developmental biology. vol 64. issue 4-5-6. 2021-10-14. PMID:32658995. |
we have focused on event specific analyses of spinal cord regeneration involving different neuronal and glial cell progenitors, such as radial glia, oligodendrocyte progenitors (opc), and schwann cells. |
2021-10-14 |
2023-08-13 |
zebrafish |
Elizabeth Minj, Shubham Upadhayay, Sidharth Meha. Nrf2/HO-1 Signaling Activator Acetyl-11-keto-beta Boswellic Acid (AKBA)-Mediated Neuroprotection in Methyl Mercury-Induced Experimental Model of ALS. Neurochemical research. vol 46. issue 11. 2021-10-04. PMID:34075522. |
mehg exposure also leads to oligodendrocyte destruction, glial cell overactivation, and demyelination of motor neurons in the motor cortex and spinal cord. |
2021-10-04 |
2023-08-13 |
rat |
Kaitlyn Koenig Thompson, Stella E Tsirk. Immunosuppression in Multiple Sclerosis and Other Neurologic Disorders. Handbook of experimental pharmacology. 2021-10-01. PMID:34595582. |
multiple sclerosis (ms) is an autoimmune disease of the central nervous system (cns) characterized by peripheral immune cell infiltration into the brain and spinal cord, demyelination, glial cell activation, and neuronal damage. |
2021-10-01 |
2023-08-13 |
Not clear |
Nilesh M Agalave, Prapti H Mody, Thomas A Szabo-Pardi, Han S Jeong, Michael D Burto. Neuroimmune Consequences of eIF4E Phosphorylation on Chemotherapy-Induced Peripheral Neuropathy. Frontiers in immunology. vol 12. 2021-09-20. PMID:33912169. |
in this study, we used wild type and eif4e-mutant mice of both sexes to investigate the role of cap-dependent translation and the contribution of immune cells and nociceptors in the periphery and glia in the spinal cord during paclitaxel-induced peripheral neuropathy. |
2021-09-20 |
2023-08-13 |
mouse |
Rachel M Bailey, Alejandra Rozenberg, Steven J Gra. Comparison of high-dose intracisterna magna and lumbar puncture intrathecal delivery of AAV9 in mice to treat neuropathies. Brain research. vol 1739. 2021-09-07. PMID:32289279. |
we report that an intrathecal gene delivery of aav9 in mice leads to stable transduction of neurons and glia in the brain and spinal cord and has a widespread distribution that includes components of the pns. |
2021-09-07 |
2023-08-13 |
mouse |
Narjes Shahsavani, Arsalan Alizadeh, Hardeep Kataria, Soheila Karimi-Abdolrezae. Availability of neuregulin-1beta1 protects neurons in spinal cord injury and against glutamate toxicity through caspase dependent and independent mechanisms. Experimental neurology. vol 345. 2021-09-07. PMID:34314724. |
nrg-1β1 is well-known for its critical roles in the development, maintenance and physiology of neurons and glia in the developing and adult spinal cord. |
2021-09-07 |
2023-08-13 |
rat |
Jalal Ali Jalal, Anjam Ibrahim Sulaiman Rowandizy, Ava Taher Ismae. Immunohistochemical expression of ATRX in gliomas. Cellular and molecular biology (Noisy-le-Grand, France). vol 66. issue 7. 2021-08-05. PMID:33287933. |
glioma is one of the primary tumors of the central nervous system that occurs in the spinal cord or brain and the origin of the tumor is from glial cell cells. |
2021-08-05 |
2023-08-13 |
Not clear |
Camila R Ferraz, Thacyana T Carvalho, Victor Fattori, Telma Saraiva-Santos, Felipe A Pinho-Ribeiro, Sergio M Borghi, Marília F Manchope, Tiago H Zaninelli, Thiago M Cunha, Rubia Casagrande, Patricia B Clissa, Waldiceu A Verr. Jararhagin, a snake venom metalloproteinase, induces mechanical hyperalgesia in mice with the neuroinflammatory contribution of spinal cord microglia and astrocytes. International journal of biological macromolecules. vol 179. 2021-07-26. PMID:33662422. |
however, the role of the spinal cord glia in pain processing after peripheral stimulus of jararhagin has not been investigated. |
2021-07-26 |
2023-08-13 |
mouse |
Martin Marsala, Kota Kamizato, Takahiro Tadokoro, Michael Navarro, Stefan Juhas, Jana Juhasova, Silvia Marsala, Hana Studenovska, Vladimir Proks, Tom Hazel, Karl Johe, Manabu Kakinohana, Shawn Driscoll, Thomas Glenn, Samuel Pfaff, Joseph Ciacc. Spinal parenchymal occupation by neural stem cells after subpial delivery in adult immunodeficient rats. Stem cells translational medicine. vol 9. issue 2. 2021-07-21. PMID:31800978. |
in the outermost layer of the spinal cord, injected hnscs differentiated into glia limitans-forming astrocytes and expressed human-specific superoxide dismutase and laminin. |
2021-07-21 |
2023-08-13 |
human |
Ilyas M Kabdesh, Svetlana S Arkhipova, Yana O Mukhamedshina, Victoria James, Albert A Rizvanov, Yuri A Chelyshe. The Function of NG2/CSPG4-expressing Cells in the Rat Spinal Cord Injury: An Immunoelectron Microscopy Study. Neuroscience. vol 467. 2021-07-12. PMID:34102261. |
in the intact spinal cord, ng2/cspg4 expression was detected on the cell membrane and in the cytoplasm of ng2 glia and was absent in neurons. |
2021-07-12 |
2023-08-13 |
rat |
Günther K H Zupan. Adult neurogenesis in the central nervous system of teleost fish: from stem cells to function and evolution. The Journal of experimental biology. vol 224. issue 8. 2021-07-09. PMID:33914040. |
new cells, including neurons and glia, arise from neural stem cells harbored both in neurogenic niches and outside these niches (such as the ependymal layer and parenchyma in the spinal cord, respectively). |
2021-07-09 |
2023-08-13 |
Not clear |
Bin Lv, Xing Zhang, Jishan Yuan, Yongxin Chen, Hua Ding, Xinbing Cao, Anquan Huan. Biomaterial-supported MSC transplantation enhances cell-cell communication for spinal cord injury. Stem cell research & therapy. vol 12. issue 1. 2021-07-05. PMID:33413653. |
the cell types that primarily comprise the spinal cord are neurons and several categories of glia, including astrocytes, oligodendrocytes, and microglia. |
2021-07-05 |
2023-08-13 |
Not clear |
Michael J Lacagnina, Jiahe Li, Sabina Lorca, Kenner C Rice, Kimberly Sullivan, James P O'Callaghan, Peter M Grac. A role for neuroimmune signaling in a rat model of Gulf War Illness-related pain. Brain, behavior, and immunity. vol 91. 2021-05-27. PMID:33127584. |
such allodynia was associated with elevation of markers for activated microglia/macrophages (cd11b) and astrocytes/satellite glia (gfap) in the lumbar dorsal spinal cord and dorsal root ganglia (drg). |
2021-05-27 |
2023-08-13 |
rat |
Wenjiao Tai, Wei Wu, Lei-Lei Wang, Haoqi Ni, Chunhai Chen, Jianjing Yang, Tong Zang, Yuhua Zou, Xiao-Ming Xu, Chun-Li Zhan. In vivo reprogramming of NG2 glia enables adult neurogenesis and functional recovery following spinal cord injury. Cell stem cell. vol 28. issue 5. 2021-05-19. PMID:33675690. |
in vivo reprogramming of ng2 glia enables adult neurogenesis and functional recovery following spinal cord injury. |
2021-05-19 |
2023-08-13 |
Not clear |
Alison L Bembrick, Damien C Boorman, Kevin A Kea. Disability-specific genes GRIN1, GRIN2 and CNR1 show injury-dependent protein expression in the lumbar spinal cord of CCI rats. Neuroscience letters. vol 728. 2021-05-17. PMID:32320718. |
the sensory changes triggered by peripheral nerve injury result from functional changes in both neurons and glia in the dorsal horn of the spinal cord. |
2021-05-17 |
2023-08-13 |
rat |