Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Yingjuan Xu, Jiling Zhang, Zeman Fang, Handi Zhan. The effects of social defeat stress on hippocampal glial cells and interleukin-6 in adolescence and adulthood. Neuroreport. vol 33. issue 18. 2022-11-11. PMID:36367792. |
the hippocampal microglia, astrocyte, and il-6 levels were measured 24 h and 3 weeks after the end of stress exposure. |
2022-11-11 |
2023-08-14 |
mouse |
Yingjuan Xu, Jiling Zhang, Zeman Fang, Handi Zhan. The effects of social defeat stress on hippocampal glial cells and interleukin-6 in adolescence and adulthood. Neuroreport. vol 33. issue 18. 2022-11-11. PMID:36367792. |
microglia activation characterized by increased ionized calcium-binding adapter molecule 1 positive cell numbers or staining area in the ca1 and ca3 regions of the hippocampus were observed 24 h after the end of stress, which did not last into the adulthood. |
2022-11-11 |
2023-08-14 |
mouse |
Yi Tian, Meihui Li, Shanshan Zhang, Juntao Hu, Haoran Wu, Mitchell Wan, Jingxin Xue, Leilei Wang, Honglei Xiao, Guomin Zhou, Kaidi Wang, Qiong Li. Microglia activation in the hippocampus mediates retinal degeneration-induced depressive-like behaviors via the NLRP3/IL-1β pathway. Brain research bulletin. 2022-11-04. PMID:36332880. |
microglia activation in the hippocampus mediates retinal degeneration-induced depressive-like behaviors via the nlrp3/il-1β pathway. |
2022-11-04 |
2023-08-14 |
mouse |
Mojtaba Ehsanifar, Zeinab Montazeri, Mahmoud Salami Zavareh, Mehravar Rafati, Jie Wan. Cognitive impairment, depressive-like behaviors and hippocampal microglia activation following exposure to air pollution nanoparticles. Environmental science and pollution research international. 2022-11-03. PMID:36327074. |
cognitive impairment, depressive-like behaviors and hippocampal microglia activation following exposure to air pollution nanoparticles. |
2022-11-03 |
2023-08-14 |
mouse |
Mojtaba Ehsanifar, Zeinab Montazeri, Mahmoud Salami Zavareh, Mehravar Rafati, Jie Wan. Cognitive impairment, depressive-like behaviors and hippocampal microglia activation following exposure to air pollution nanoparticles. Environmental science and pollution research international. 2022-11-03. PMID:36327074. |
the number of activated microglia increased in the dentate gyrus (dg) and ca1 regions of the hippocampus in dep-exposed mice. |
2022-11-03 |
2023-08-14 |
mouse |
Julianna Lilienberg, Ágota Apáti, János M Réthelyi, László Homoly. Microglia modulate proliferation, neurite generation and differentiation of human neural progenitor cells. Frontiers in cell and developmental biology. vol 10. 2022-10-31. PMID:36313581. |
despite the fact that neural progenitor cells (npcs) and hippocampal neurons represent cell populations, which play pivotal role in neural regeneration, interaction between microglia and these cell types is poorly studied. |
2022-10-31 |
2023-08-14 |
human |
Julianna Lilienberg, Ágota Apáti, János M Réthelyi, László Homoly. Microglia modulate proliferation, neurite generation and differentiation of human neural progenitor cells. Frontiers in cell and developmental biology. vol 10. 2022-10-31. PMID:36313581. |
we also studied how microglia influence neurite development and differentiation of hippocampal dentate gyrus granule cells differentiated from npcs. |
2022-10-31 |
2023-08-14 |
human |
Moonseok Choi, Dongsoo Kim, Young-Jin Youn, Junghwa Ryu, Yun Ha Jeon. Effect of Obesity and High-Density Lipoprotein Concentration on the Pathological Characteristics of Alzheimer's Disease in High-Fat Diet-Fed Mice. International journal of molecular sciences. vol 23. issue 20. 2022-10-27. PMID:36293147. |
the reactivity of astrocytes and microglia in the dentate gyrus of the hippocampus and fornix of the hypothalamus in 5xfad mice was decreased in the transgenic (tg)-hfd high group. |
2022-10-27 |
2023-08-14 |
mouse |
Derek R Fisher, Tong Zheng, Donna F Bielinski, Megan E Kelly, Danielle S Cahoon, Barbara Shukitt-Hal. Phytochemical Combination Is More Effective than Individual Components in Reducing Stress Signaling in Rat Hippocampal Neurons and Microglia In Vitro. International journal of molecular sciences. vol 23. issue 20. 2022-10-27. PMID:36293507. |
phytochemical combination is more effective than individual components in reducing stress signaling in rat hippocampal neurons and microglia in vitro. |
2022-10-27 |
2023-08-14 |
rat |
Jingjing Shao, Xiaoxuan Ma, Linlin Qu, Pei Ma, Rong Huang, Daidi Fa. Ginsenoside Rh4 remodels the periphery microenvironment by targeting the brain-gut axis to alleviate depression-like behaviors. Food chemistry. vol 404. issue Pt B. 2022-10-25. PMID:36283312. |
concurrently, rh4 inhibits hippocampal neuronal apoptosis and synaptic structural damage due to the overexpression of proinflammatory cytokines and overactivation of microglia and astrocytes by inhibiting the immune-inflammatory response and signaling molecular interaction pathways. |
2022-10-25 |
2023-08-14 |
mouse |
Lynde M Wangler, Chelsea E Bray, Jonathan M Packer, Zoe M Tapp, Amara C Davis, Shane M O'Neil, Kara Baetz, Michelle Ouviña, Mollie Witzel, Jonathan P Godbou. Amplified Gliosis and Interferon-Associated Inflammation in the Aging Brain Following Diffuse Traumatic Brain Injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-10-18. PMID:36257689. |
there was enhanced morphological restructuring of microglia and astrocytes 7 dpi in the cortex and hippocampus of aged mice compared to adults. |
2022-10-18 |
2023-08-14 |
mouse |
R Infantino, S Boccella, D Scuteri, M Perrone, F Ricciardi, R M Vitale, R Bonsale, A Parente, I Allocca, A Virtuoso, C De Luca, C Belardo, P Amodeo, V Gentile, G Cirillo, G Bagetta, L Luongo, S Maione, F Guid. 2-pentadecyl-2-oxazoline prevents cognitive and social behaviour impairments in the Amyloid β-induced Alzheimer-like mice model: Bring the α2 adrenergic receptor back into play. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 156. 2022-10-17. PMID:36252359. |
consistently, electrophysiological analysis showed a recovery of the long-term potentiation in the hippocampus (lateral entorhinal cortex-dentate gyrus pathway), while neuroinflammation, i.e., increased pro-inflammatory cytokines levels and microglia cells density were reduced. |
2022-10-17 |
2023-08-14 |
mouse |
Arbthip Suwaluk, Nuanchan Chutabhakdiku. Long-Term Effects of Prenatal Stress on the Development of Prefrontal Cortex in the Adolescent Offspring. Journal of chemical neuroanatomy. 2022-10-14. PMID:36241049. |
previous studies have revealed the long-term effects of prenatal stress (ps) on microglia activation and neuroinflammation in the hippocampus of the offspring. |
2022-10-14 |
2023-08-14 |
Not clear |
Adriana Fernanda K Vizuete, Fernanda Fróes, Marina Seady, Caroline Zanotto, Larissa Daniele Bobermin, Ana Cristina Roginski, Moacir Wajner, André Quincozes-Santos, Carlos Alberto Gonçalve. Early effects of LPS-induced neuroinflammation on the rat hippocampal glycolytic pathway. Journal of neuroinflammation. vol 19. issue 1. 2022-10-11. PMID:36221097. |
moreover, the inhibition of s100b, a protein predominantly synthesized and secreted by astrocytes, inhibition of microglia activation and abrogation of nlrp3 inflammasome assembly confirmed the role of neuroinflammation in the upregulation of glycolysis in the hippocampus. |
2022-10-11 |
2023-08-14 |
rat |
O V Kirik, O S Alekseeva, D L Tsyba, D E Korzhevski. Reaction of the Hippocampal Microglia to Hyperbaric Oxygen. Bulletin of experimental biology and medicine. 2022-10-09. PMID:36210418. |
reaction of the hippocampal microglia to hyperbaric oxygen. |
2022-10-09 |
2023-08-14 |
rat |
Teresa A Milner, Ryan X Chen, Diedreanna Welington, Batsheva R Rubin, Natalina H Contoreggi, Megan A Johnson, Sanoara Mazid, Jose Marques-Lopes, Roberta Marongiu, Michael J Glas. Angiotensin II differentially affects hippocampal glial inflammatory markers in young adult male and female mice. Learning & memory (Cold Spring Harbor, N.Y.). vol 29. issue 9. 2022-10-07. PMID:36206386. |
hypertension is a risk factor for neurodegenerative disorders involving inflammation and inflammatory cytokine-producing brain cells (microglia and astrocytes) in the hippocampus and medial prefrontal cortex (mpfc). |
2022-10-07 |
2023-08-14 |
mouse |
Sarah Katharina Steffens, Tarja Helena Stenberg, Henna-Kaisa Margareta Wigre. Alterations in microglial morphology concentrate in the habitual sleeping period of the mouse. Glia. 2022-10-05. PMID:36196985. |
as microglia express regional heterogeneity and are influenced by local neuronal activity, we chose to investigate three interconnected and functionally well-characterized brain areas: the somatosensory cortex (sc), the dorsal hippocampus (hc), and the basal forebrain (bf). |
2022-10-05 |
2023-08-14 |
mouse |
Yangming Zhang, Yuqiao Xie, Zishuo Cheng, Kaiwen Xi, Xin Huang, Fang Kuang, Wenting Wang, Tiaotiao Liu, Baolin Guo, Shengxi W. Quercetin ameliorates memory impairment by inhibiting abnormal microglial activation in a mouse model of paradoxical sleep deprivation. Biochemical and biophysical research communications. vol 632. 2022-10-03. PMID:36191372. |
our results provided experimental evidence for the therapeutic effects of quercetin on psd-related memory impairments by suppressing tlr4/myd88/nf-κb signaling that mediated abnormal microglia activation in the hippocampus. |
2022-10-03 |
2023-08-14 |
mouse |
Priya Rangan, Fleur Lobo, Edoardo Parrella, Nicolas Rochette, Marco Morselli, Terri-Leigh Stephen, Anna Laura Cremonini, Luca Tagliafico, Angelica Persia, Irene Caffa, Fiammetta Monacelli, Patrizio Odetti, Tommaso Bonfiglio, Alessio Nencioni, Martina Pigliautile, Virginia Boccardi, Patrizia Mecocci, Christian J Pike, Pinchas Cohen, Mary Jo LaDu, Matteo Pellegrini, Kyle Xia, Katelynn Tran, Brandon Ann, Dolly Chowdhury, Valter D Long. Fasting-mimicking diet cycles reduce neuroinflammation to attenuate cognitive decline in Alzheimer's models. Cell reports. vol 40. issue 13. 2022-09-28. PMID:36170815. |
in 3xtg mice, long-term fmd cycles reduce hippocampal aβ load and hyperphosphorylated tau, enhance genesis of neural stem cells, decrease microglia number, and reduce expression of neuroinflammatory genes, including superoxide-generating nadph oxidase (nox2). |
2022-09-28 |
2023-08-14 |
mouse |
Ying Tu, Yongyong Yang, Yue Wang, Nana Wu, Junyan Tao, Guanghong Yang, Mingdan Yo. Developmental exposure to chlorpyrifos causes neuroinflammation via necroptosis in mouse hippocampus and human microglial cell line. Environmental pollution (Barking, Essex : 1987). 2022-09-26. PMID:36155221. |
developmental exposure to chlorpyrifos causes neuroinflammation via necroptosis in mouse hippocampus and human microglial cell line. |
2022-09-26 |
2023-08-14 |
mouse |