Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Ji Hyeon Ahn, Bich Na Shin, Joon Ha Park, Tae-Kyeong Lee, Young Eun Park, Jae-Chul Lee, Go Eun Yang, Myoung Cheol Shin, Jun Hwi Cho, Kyu Chang Lee, Moo-Ho Won, Hyeyoung Ki. Pre- and Post-Treatment with Novel Antiepileptic Drug Oxcarbazepine Exerts Neuroprotective Effect in the Hippocampus in a Gerbil Model of Transient Global Cerebral Ischemia. Brain sciences. vol 9. issue 10. 2020-09-28. PMID:31627311. |
in addition, pre- and post-treatment with oxcarbazepine (200 mg/kg) significantly ameliorated astrocytes and microglia activation in the ischemic cornu ammonis 1 subfield. |
2020-09-28 |
2023-08-13 |
Not clear |
Gaurav Singhal, Julie Morgan, Magdalene C Jawahar, Frances Corrigan, Emily J Jaehne, Catherine Toben, Jim Manavis, Anthony J Hannan, Bernhard T Baun. Duration of Environmental Enrichment Determines Astrocyte Number and Cervical Lymph Node T Lymphocyte Proportions but Not the Microglial Number in Middle-Aged C57BL/6 Mice. Frontiers in cellular neuroscience. vol 14. 2020-09-28. PMID:32256319. |
ee, regardless of duration, caused an increase in microglia number within the dentate gyrus, ca1 and ca3 hippocampal regions, but only long-term ee increased astrocytes number within the dentate gyrus and ca3 hippocampal regions. |
2020-09-28 |
2023-08-13 |
mouse |
Shi Yu, Hujing Zhang, Yue Hei, Xicai Yi, Andrius Baskys, Weiping Liu, Qianfa Lon. High mobility group box-1 (HMGB1) antagonist BoxA suppresses status epilepticus-induced neuroinflammatory responses associated with Toll-like receptor 2/4 down-regulation in rats. Brain research. vol 1717. 2020-09-24. PMID:30986405. |
in ex vivo experiments, post-se microglia cells were isolated from the hippocampal ca1 area and subjected to lipopolysaccharide (lps) stimulation followed by inflammatory cytokine il-1β and il-6 by qpcr and hmgb1, tlr2, tlr3 by western blotting. |
2020-09-24 |
2023-08-13 |
rat |
Nathan T Fiore, Paul J Austi. Peripheral Nerve Injury Triggers Neuroinflammation in the Medial Prefrontal Cortex and Ventral Hippocampus in a Subgroup of Rats with Coincident Affective Behavioural Changes. Neuroscience. vol 416. 2020-09-24. PMID:31401182. |
this includes increased expression of il-1β, il-6 and mcp-1, increased phospho-p38 mapk expression in neurons and microglia, and a shift to a reactive microglial morphology in the caudal pl and il, ventral ca1 and dg. |
2020-09-24 |
2023-08-13 |
rat |
Shai Shoham, Michal Linial, Marta Weinstoc. Age-Induced Spatial Memory Deficits in Rats Are Correlated with Specific Brain Region Alterations in Microglial Morphology and Gene Expression. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 14. issue 2. 2020-09-11. PMID:30343448. |
aging did not change the number of microglia in the parietal cortex (pc) or hippocampal ca1 region (ca1-hc), but decreased microglial process tips in the ca1-hc, increased the area fraction stained by cd11b and number of bulbs on processes in pc and ca1-hc and thickness of microglial processes in corpus callosum (cc) and fornix (fx). |
2020-09-11 |
2023-08-13 |
rat |
Tae-Kyeong Lee, Ji Hyeon Ahn, Cheol Woo Park, Bora Kim, Young Eun Park, Jae-Chul Lee, Joon Ha Park, Go Eun Yang, Myoung Cheol Shin, Jun Hwi Cho, Il-Jun Kang, Moo-Ho Wo. Pre-Treatment with Laminarin Protects Hippocampal CA1 Pyramidal Neurons and Attenuates Reactive Gliosis Following Transient Forebrain Ischemia in Gerbils. Marine drugs. vol 18. issue 1. 2020-08-13. PMID:31940961. |
in contrast, pretreatment with 50 or 100 mg/kg laminarin protected neurons, attenuated reactive gliosis and reduced pro-inflammatory m1 microglia in the ca1 field following tfi. |
2020-08-13 |
2023-08-13 |
Not clear |
Man Cheng, Liu Yang, Zhiping Dong, Mengying Wang, Yan Sun, Huan Liu, Xuan Wang, Na Sai, Guowei Huang, Xumei Zhan. Folic acid deficiency enhanced microglial immune response via the Notch1/nuclear factor kappa B p65 pathway in hippocampus following rat brain I/R injury and BV2 cells. Journal of cellular and molecular medicine. vol 23. issue 7. 2020-08-06. PMID:31087489. |
our results exhibited that fd worsened neuronal cell death and exaggerated microglia activation in the hippocampal ca1, ca3 and dentate gyrus (dg) subregions after cerebral ischaemia/reperfusion. |
2020-08-06 |
2023-08-13 |
rat |
Matteo Pedrazzoli, Morris Losurdo, Giovanna Paolone, Manuela Medelin, Lejdi Jaupaj, Barbara Cisterna, Anna Slanzi, Manuela Malatesta, Silvia Coco, Mario Buffell. Glucocorticoid receptors modulate dendritic spine plasticity and microglia activity in an animal model of Alzheimer's disease. Neurobiology of disease. vol 132. 2020-08-06. PMID:31394203. |
we found that dexamethasone, an agonist of grs, was able to significantly reduce dendritic spine density and induced proliferation and activation of microglia in ca1 region of hippocampus of 3xtg-ad mice at 6 and 10 months of age. |
2020-08-06 |
2023-08-13 |
mouse |
Qinwen Mao, Xiaojing Zheng, Tamar Gefen, Emily Rogalski, Callen L Spencer, Rosa Rademakers, Angela J Fought, Missia Kohler, Sandra Weintraub, Haibin Xia, Marek-Marsel Mesulam, Eileen H Bigi. FTLD-TDP With and Without GRN Mutations Cause Different Patterns of CA1 Pathology. Journal of neuropathology and experimental neurology. vol 78. issue 9. 2020-06-18. PMID:31361008. |
in addition, the ca1 region in grn mutation cases contained more rod-like microglia, which also had reduced pgrn expression. |
2020-06-18 |
2023-08-13 |
Not clear |
Joon Ha Park, Ji Hyeon Ahn, Dae Won Kim, Tae-Kyeong Lee, Cheol Woo Park, Young Eun Park, Jae-Chul Lee, Hyang-Ah Lee, Go Eun Yang, Moo-Ho Won, Choong-Hyun Le. Altered Nurr1 protein expression in the hippocampal CA1 region following transient global cerebral ischemia. Molecular medicine reports. vol 21. issue 1. 2020-06-03. PMID:31746417. |
additionally, nurr1 immunoreactivity was newly expressed in microglia in the ca1 subfield at 4 days post‑ischemia. |
2020-06-03 |
2023-08-13 |
Not clear |
Radha Raghuraman, Aparna Karthikeyan, Wong Lik Wei, S Thameem Dheen, Sreedharan Sajikuma. Activation of microglia in acute hippocampal slices affects activity-dependent long-term potentiation and synaptic tagging and capture in area CA1. Neurobiology of learning and memory. vol 163. 2020-04-02. PMID:31278985. |
activation of microglia in acute hippocampal slices affects activity-dependent long-term potentiation and synaptic tagging and capture in area ca1. |
2020-04-02 |
2023-08-13 |
Not clear |
I Berkiks, L M Garcia-Segura, A Nassiri, A Mesfioui, A Ouichou, S Boulbaroud, Y Bahbiti, A B Lopez-Rodriguez, El Hasnaoui, A El Hessn. The sex differences of the behavior response to early Life immune stimulation: Microglia and astrocytes involvement. Physiology & behavior. vol 199. 2020-03-19. PMID:30529512. |
hippocampal proinflammatory cytokine tnf-alpha concentration and the number of astrocytes and microglia were estimated in the dentate gyrus, ca1, and ca3 in two regions of the hippocampus (ventral and dorsal). |
2020-03-19 |
2023-08-13 |
rat |
Eva-Lotta von Rüden, Fabio Wolf, Fabio Gualtieri, Michael Keck, Clayton R Hunt, Tej K Pandita, Heidrun Potschk. Genetic and Pharmacological Targeting of Heat Shock Protein 70 in the Mouse Amygdala-Kindling Model. ACS chemical neuroscience. vol 10. issue 3. 2020-03-05. PMID:30396268. |
interestingly, hsp70 deficiency resulted in enhanced microglia activation in the ca1 region. |
2020-03-05 |
2023-08-13 |
mouse |
Eva-Lotta von Rüden, Fabio Wolf, Fabio Gualtieri, Michael Keck, Clayton R Hunt, Tej K Pandita, Heidrun Potschk. Genetic and Pharmacological Targeting of Heat Shock Protein 70 in the Mouse Amygdala-Kindling Model. ACS chemical neuroscience. vol 10. issue 3. 2020-03-05. PMID:30396268. |
celastrol treatment had no impact on kindling progression but reduced postkindling seizure thresholds and enhanced microglia activation in ca1 and ca3. |
2020-03-05 |
2023-08-13 |
mouse |
Liqing Zhou, Long Chen, Xiaohuan Li, Tingyu Li, Zhifang Dong, Yu Tian Wan. Food allergy induces alteration in brain inflammatory status and cognitive impairments. Behavioural brain research. vol 364. 2020-02-13. PMID:29339006. |
in particular, food allergy increased the number of total microglia and the percentage of active microglia in the cerebral cortex and hippocampal ca1 areas, and induced the increase of tnf-α in the cerebral cortex. |
2020-02-13 |
2023-08-13 |
Not clear |
Ji Hyeon Ahn, Dae Won Kim, Joon Ha Park, Tae-Kyeong Lee, Hyang-Ah Lee, Moo-Ho Won, Choong-Hyun Le. Expression changes of CX3CL1 and CX3CR1 proteins in the hippocampal CA1 field of the gerbil following transient global cerebral ischemia. International journal of molecular medicine. vol 44. issue 3. 2020-02-04. PMID:31524247. |
these results showed that cx3cl1 and cx3cr1 protein expression levels in pyramidal cells and microglia in the hippocampal ca1 field following tgci were changed, indicating that tgci‑induced expression changes of cx3cl1 and cx3cr1 proteins might be closely associated with tgci‑induced delayed neuronal death and microglial activation. |
2020-02-04 |
2023-08-13 |
Not clear |
Jean Shin, Leon French, Ting Xu, Gabriel Leonard, Michel Perron, G Bruce Pike, Louis Richer, Suzanne Veillette, Zdenka Pausova, Tomáš Pau. Cell-Specific Gene-Expression Profiles and Cortical Thickness in the Human Brain. Cerebral cortex (New York, N.Y. : 1991). vol 28. issue 9. 2019-11-13. PMID:28968835. |
we also show that inter-regional profiles in cortical thinning relate to those in the expression of genes marking ca1 and s1 pyramidal cells, astrocytes and microglia. |
2019-11-13 |
2023-08-13 |
human |
Fengling Li, Lei Li. Comparison of kainate-induced seizures, cognitive impairment and hippocampal damage in male and female mice. Life sciences. vol 232. 2019-09-27. PMID:31269415. |
ka-induced neurodegeneration in the whole hippocampus, particularly in ca1 and ca3 subregions, along with the deteriorative reactive gliosis in astrocytes and microglia, was more severe in males than that in females. |
2019-09-27 |
2023-08-13 |
mouse |
Yuan Gao, En-Jie Liu, Wei-Jin Wang, Ya-Li Wang, Xiao-Guang Li, Xin Wang, Shi-Hong Li, Shu-Juan Zhang, Meng-Zhu Li, Qiu-Zhi Zhou, Xiao-Bing Long, Hua-Qiu Zhang, Jian-Zhi Wan. Microglia CREB-Phosphorylation Mediates Amyloid-β-Induced Neuronal Toxicity. Journal of Alzheimer's disease : JAD. vol 66. issue 1. 2019-09-19. PMID:30282353. |
aβ treatment for 24 h increased ps133-creb level in microglia of the hippocampal non-granular cell layers with remarkably decreased ps133-creb immunoreactivity in neurons of the hippocampal granular cell layers, including ca1, ca3, and dg subsets. |
2019-09-19 |
2023-08-13 |
mouse |
Mélanie Morin-Brureau, Giampaolo Milior, Juliette Royer, Farah Chali, Caroline Le Duigou, Etienne Savary, Corinne Blugeon, Laurent Jourdren, David Akbar, Sophie Dupont, Vincent Navarro, Michel Baulac, Franck Bielle, Bertrand Mathon, Stéphane Clemenceau, Richard Mile. Microglial phenotypes in the human epileptic temporal lobe. Brain : a journal of neurology. vol 141. issue 12. 2019-07-15. PMID:30462183. |
the repairing interleukin, il-10, regulates the basal phenotype of microglia in the ca1 and ca3 regions with neuronal loss and gliosis. |
2019-07-15 |
2023-08-13 |
mouse |