| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M R Cookson, P J Sha. Oxidative stress and motor neurone disease. Brain pathology (Zurich, Switzerland). vol 9. issue 1. 1999-06-03. PMID:9989458. |
several lines of evidence suggest that alterations in the glutamatergic neurotransmitter system may also play a key role in the injury to motor neurones in sporadic mnd. |
1999-06-03 |
2023-08-12 |
mouse |
| M M Adams, R A Flagg, A C Gor. Perinatal changes in hypothalamic N-methyl-D-aspartate receptors and their relationship to gonadotropin-releasing hormone neurons. Endocrinology. vol 140. issue 5. 1999-05-06. PMID:10218982. |
taken together, these data indicate that glutamatergic inputs to the poa-ah change dramatically during the early postnatal period, before puberty and before the gnrh system is fully responsive to glutamate, consistent with the hypothesis that the maturation of inputs to gnrh neurons, and the establishment of the proper neurotransmitter "milieu" enabling the activation of gnrh neurons, occurs before the onset of puberty. |
1999-05-06 |
2023-08-12 |
human |
| A DiAntonio, S A Petersen, M Heckmann, C S Goodma. Glutamate receptor expression regulates quantal size and quantal content at the Drosophila neuromuscular junction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 8. 1999-04-27. PMID:10191319. |
at the drosophila glutamatergic neuromuscular junction, the postsynaptic cell can regulate synaptic strength by both changing its sensitivity to neurotransmitter and generating a retrograde signal that regulates presynaptic transmitter release. |
1999-04-27 |
2023-08-12 |
drosophila_melanogaster |
| K Weissenborn, H Kolb. The basal ganglia and portal-systemic encephalopathy. Metabolic brain disease. vol 13. issue 4. 1999-04-14. PMID:10206819. |
current hypotheses on the pathophysiology of pse usually deal with metabolic toxins like ammonia or disturbances in neurotransmitter systems, especially glutamatergic or gaba-ergic neurotransmission. |
1999-04-14 |
2023-08-12 |
Not clear |
| G J Evans, J M Pococ. Modulation of neurotransmitter release by dihydropyridine-sensitive calcium channels involves tyrosine phosphorylation. The European journal of neuroscience. vol 11. issue 1. 1999-04-01. PMID:9987031. |
kcl stimulation in the absence of external ca2+ followed by the readdition of ca2+ allows the coupling of a class of l-type ca2+ channels to neurotransmitter exocytosis as assessed by loading of glutamatergic pools with [3h]-d-aspartate. |
1999-04-01 |
2023-08-12 |
rat |
| Y Kustova, J H Ha, M G Espey, Y Sei, D Morse, A S Basil. The pattern of neurotransmitter alterations in LP-BM5 infected mice is consistent with glutamatergic hyperactivation. Brain research. vol 793. issue 1-2. 1999-03-29. PMID:9630562. |
the pattern of neurotransmitter alterations in lp-bm5 infected mice is consistent with glutamatergic hyperactivation. |
1999-03-29 |
2023-08-12 |
mouse |
| F Fadda, Z L Rossett. Chronic ethanol consumption: from neuroadaptation to neurodegeneration. Progress in neurobiology. vol 56. issue 4. 1998-12-30. PMID:9775400. |
due to the diffuse glutamatergic innervation to all brain structures, the neuroadaptive alterations in excitatory neurotransmission can affect the function of most if not all of neurotransmitter systems. |
1998-12-30 |
2023-08-12 |
Not clear |
| A S Leonard, M A Davare, M C Horne, C C Garner, J W Hel. SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit. The Journal of biological chemistry. vol 273. issue 31. 1998-09-10. PMID:9677374. |
rapid glutamatergic synaptic transmission is mediated by ionotropic glutamate receptors and depends on their precise localization at postsynaptic membranes opposing the presynaptic neurotransmitter release sites. |
1998-09-10 |
2023-08-12 |
rat |
| A Dalia, N J Uretsky, L J Wallac. Dopaminergic agonists administered into the nucleus accumbens: effects on extracellular glutamate and on locomotor activity. Brain research. vol 788. issue 1-2. 1998-07-23. PMID:9554973. |
the hypothesis to be tested was that increased dopaminergic transmission induced by amphetamine in the nucleus accumbens results in increased glutamatergic neurotransmission in this brain area and that the increase in level of this neurotransmitter contributes to behavioral effects of psychostimulant drugs. |
1998-07-23 |
2023-08-12 |
Not clear |
| P Li, M Zhu. Silent glutamatergic synapses and nociception in mammalian spinal cord. Nature. vol 393. issue 6686. 1998-07-01. PMID:9641681. |
serotonin (5-hydroxytryptamine, 5-ht), an important neurotransmitter of the raphe-spinal projecting pathway, transforms silent glutamatergic synapses into functional ones. |
1998-07-01 |
2023-08-12 |
Not clear |
| K E Vanove. Effects of AMPA receptor antagonists on dopamine-mediated behaviors in mice. Psychopharmacology. vol 136. issue 2. 1998-06-18. PMID:9551768. |
current data indicate that dopaminergic and glutamatergic neurotransmitter systems interact. |
1998-06-18 |
2023-08-12 |
mouse |
| V C Kürschner, R L Petruzzi, G T Golden, W H Berrettini, T N Ferrar. Kainate and AMPA receptor binding in seizure-prone and seizure-resistant inbred mouse strains. Brain research. vol 780. issue 1. 1998-04-29. PMID:9473562. |
it is unlikely, however, that these receptors account for the generation of seizures alone but rather cooperate with other glutamatergic and non-glutamatergic neurotransmitter systems. |
1998-04-29 |
2023-08-12 |
mouse |
| I D Milton, S J Banner, P G Ince, N H Piggott, A E Fray, N Thatcher, C H Horne, P J Sha. Expression of the glial glutamate transporter EAAT2 in the human CNS: an immunohistochemical study. Brain research. Molecular brain research. vol 52. issue 1. 1998-03-10. PMID:9450673. |
glutamate transporters play an essential role in terminating the excitatory glutamatergic signal at post-synaptic receptors and in protecting neurones from excitotoxic effects, as well as replenishing the neurotransmitter supply at glutamatergic synapses. |
1998-03-10 |
2023-08-12 |
human |
| P Bienkowski, E Koros, J Piasecki, W Kostowsk. Interactions of ethanol with nicotine, dizocilpine, CGP 40116, and 1-(m-chlorophenyl)-biguanide in rats. Pharmacology, biochemistry, and behavior. vol 58. issue 4. 1998-01-30. PMID:9408228. |
alternatively, a common neurotransmitter system (other than glutamatergic) mediate central stimulatory effects of ethanol and dizocilpine. |
1998-01-30 |
2023-08-12 |
rat |
| D Gao, A Benazzouz, K Bressand, B Piallat, A L Benabi. Roles of GABA, glutamate, acetylcholine and STN stimulation on thalamic VM in rats. Neuroreport. vol 8. issue 11. 1998-01-08. PMID:9261835. |
these results suggest that gabaergic, cholinergic and glutamatergic input information converge in the same vm neurons and that an increase in the delivery of glutamatergic neurotransmitter activities in the vm is involved in the process of high frequency stimulation of the stn. |
1998-01-08 |
2023-08-12 |
rat |
| J P Kelly, A S Wrynn, B E Leonar. The olfactory bulbectomized rat as a model of depression: an update. Pharmacology & therapeutics. vol 74. issue 3. 1997-11-25. PMID:9352586. |
alterations in the noradrenergic, serotonergic, cholinergic, gamma-aminobutyric acid (gaba)ergic and glutamatergic neurotransmitter systems are also associated with olfactory bulbectomy. |
1997-11-25 |
2023-08-12 |
rat |
| A Michalak, R F Butterwort. Ornithine transcarbamylase deficiency: pathogenesis of the cerebral disorder and new prospects for therapy. Metabolic brain disease. vol 12. issue 3. 1997-11-19. PMID:9346466. |
using an animal model of congenital otc deficiency, the sparse fur (spf) mouse, recent studies have revealed significant alterations of cholinergic, serotoninergic and glutamatergic neurotransmitter systems. |
1997-11-19 |
2023-08-12 |
mouse |
| L L Phillips, B G Lyeth, R J Hamm, J Y Jiang, J T Povlishock, T M Reeve. Effect of prior receptor antagonism on behavioral morbidity produced by combined fluid percussion injury and entorhinal cortical lesion. Journal of neuroscience research. vol 49. issue 2. 1997-10-16. PMID:9272642. |
we have used an animal model of traumatic brain injury (tbi) that incorporates both the neurotransmitter toxicity of fluid percussion tbi and deafferentation of bilateral entorhinal cortical (bec) lesion to explore whether administration of muscarinic cholinergic or n-methyl-d-aspartate glutamatergic antagonists prior to injury ameliorates cognitive morbidity. |
1997-10-16 |
2023-08-12 |
rat |
| T L Williams, N C Day, P G Ince, R K Kamboj, P J Sha. Calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors: a molecular determinant of selective vulnerability in amyotrophic lateral sclerosis. Annals of neurology. vol 42. issue 2. 1997-09-05. PMID:9266730. |
one potential pathogenetic mechanism is chronic toxicity due to disturbances of the glutamatergic neurotransmitter system, mediated via alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (ampa)-sensitive glutamate receptors. |
1997-09-05 |
2023-08-12 |
human |
| G Calò, S Sbrenna, C Bianchi, L Bean. Immediate and delayed effects of in vitro ischemia on glutamate efflux from guinea-pig cerebral cortex slices. Brain research. vol 751. issue 2. 1997-09-02. PMID:9099819. |
this in vitro ischemia-induced delayed potentiation of neurotransmitter efflux, until now unreported in the literature, was found to be selectively restricted to glutamatergic structures and to be mainly due to an enhancement of the exocytotic component of glutamate release. |
1997-09-02 |
2023-08-12 |
Not clear |