| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ana Lopes-Rocha, Thiago Ohno Bezerra, Roberta Zanotto, Inda Lages Nascimento, Angela Rodrigues, Cristiane Salu. The Antioxidant N-Acetyl-L-Cysteine Restores the Behavioral Deficits in a Neurodevelopmental Model of Schizophrenia Through a Mechanism That Involves Nitric Oxide. Frontiers in pharmacology. vol 13. 2022-07-29. PMID:35903343. |
analyses of markers involved in the inflammatory response, such as astrocytes (glial fibrillary acid protein, gfap) and microglia (binding adapter molecule 1, iba1), and parvalbumin (pv) positive gabaergic, were conducted in the prefrontal cortex [pfc, medial orbital cortex (mo) and prelimbic cortex (prl)] and dorsal and ventral hippocampus [ca1, ca2, ca3, and dentate gyrus (dg)] in rats under chronic treatment with nac. |
2022-07-29 |
2023-08-14 |
rat |
| Gergana Mincheva, Carla Gimenez-Garzo, Paula Izquierdo-Altarejos, Mar Martinez-Garcia, Magnus Doverskog, Thomas P Blackburn, Anneli Hällgren, Torbjörn Bäckström, Marta Llansola, Vicente Felip. Golexanolone, a GABA CNS neuroscience & therapeutics. 2022-07-26. PMID:35880480. |
golexanolone, a gaba hyperammonemic rats show peripheral inflammation, increased gabaergic neurotransmission and neuroinflammation in cerebellum and hippocampus which induce motor incoordination and cognitive impairment. |
2022-07-26 |
2023-08-14 |
rat |
| Giulia Petrini, Giulia Tomagra, Ettore Bernardi, Ekaterina Moreva, Paolo Traina, Andrea Marcantoni, Federico Picollo, Klaudia Kvaková, Petr Cígler, Ivo Pietro Degiovanni, Valentina Carabelli, Marco Genoves. Nanodiamond-Quantum Sensors Reveal Temperature Variation Associated to Hippocampal Neurons Firing. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2022-07-25. PMID:35876403. |
the results demonstrate that nitrogen-vacancy centers in nanodiamonds provide a tool for assessing various levels of neuronal spiking activity, since they are suitable for monitoring different temperature variations, respectively, associated with the spontaneous firing of hippocampal neurons, the disinhibition of gabaergic transmission and the silencing of the network. |
2022-07-25 |
2023-08-14 |
Not clear |
| Dandan Liu, Shuqiong Liu, Jiande Li, Xiaohuan Liu, Xiaoxuan Wu, Ying Peng, Qingyu She. Proteome-Wide Analysis of the Hippocampus in Adult Mice with Learning and Memory Impairment Caused by Chronic Ethanol Exposure. Neurobiology of learning and memory. 2022-07-25. PMID:35878712. |
further verification using western blotting and real-time quantitative pcr revealed that the hippocampal ctsl (cathepsin l), and pvalb (parvalbumin) showed strongest expression changes, the latter being specifically expressed in gabaergic interneurons. |
2022-07-25 |
2023-08-14 |
mouse |
| Fumi Katsuki, Dmitry Gerashchenko, Ritchie E Brow. Alterations of sleep oscillations in Alzheimer's Disease: A potential role for GABAergic neurons in the cortex, hippocampus, and thalamus. Brain research bulletin. 2022-07-19. PMID:35850189. |
alterations of sleep oscillations in alzheimer's disease: a potential role for gabaergic neurons in the cortex, hippocampus, and thalamus. |
2022-07-19 |
2023-08-14 |
mouse |
| Fumi Katsuki, Dmitry Gerashchenko, Ritchie E Brow. Alterations of sleep oscillations in Alzheimer's Disease: A potential role for GABAergic neurons in the cortex, hippocampus, and thalamus. Brain research bulletin. 2022-07-19. PMID:35850189. |
recent mechanistic studies suggest that alterations in the activity of gabaergic neurons in the cortex, hippocampus and thalamic reticular nucleus mediate sleep oscillatory changes in ad and represent a potential target for intervention. |
2022-07-19 |
2023-08-14 |
mouse |
| Zhou Lu, Huixiao Wang, Jiajie Gu, Feng Ga. Association between abnormal brain oscillations and cognitive performance in patients with bipolar disorder; Molecular mechanisms and clinical evidence. Synapse (New York, N.Y.). 2022-07-18. PMID:35849784. |
abnormal oscillations have been found to be associated with several neural dysfunctions and abnormalities contributing to bd, including abnormal gabaergic neurotransmission signaling, hippocampal cell discharge, abnormal hippocampal neurogenesis, impaired cadherin and synaptic contact-based cell adhesion processes, extended lateral ventricles, decreased prefrontal cortical gray matter, and decreased hippocampal volume. |
2022-07-18 |
2023-08-14 |
Not clear |
| Dwipayan Bhattacharya, Aundrea F Bartley, Qin Li, Lynn E Dobrun. Bicuculline Restores Frequency-Dependent Hippocampal I/E Ratio and Circuit Function in PGC-1ɑ Null Mice. Neuroscience research. 2022-07-16. PMID:35842011. |
loss of pgc-1α (peroxisome proliferator activated receptor γ coactivator 1α) causes transcriptional dysregulation in hippocampal gabaergic interneurons. |
2022-07-16 |
2023-08-14 |
mouse |
| Peter J Schuette, Juliane M Ikebara, Sandra Maesta-Pereira, Anita Torossian, Ekayana Sethi, Alexandre H Kihara, Jonathan C Kao, Fernando M C V Reis, Avishek Adhikar. GABAergic CA1 neurons are more stable following context changes than glutamatergic cells. Scientific reports. vol 12. issue 1. 2022-06-20. PMID:35725588. |
the ca1 region of the hippocampus contains both glutamatergic pyramidal cells and gabaergic interneurons. |
2022-06-20 |
2023-08-14 |
mouse |
| Peter J Schuette, Juliane M Ikebara, Sandra Maesta-Pereira, Anita Torossian, Ekayana Sethi, Alexandre H Kihara, Jonathan C Kao, Fernando M C V Reis, Avishek Adhikar. GABAergic CA1 neurons are more stable following context changes than glutamatergic cells. Scientific reports. vol 12. issue 1. 2022-06-20. PMID:35725588. |
in contrast, these classic hippocampal experiments have never been conducted with ca1 gabaergic cells. |
2022-06-20 |
2023-08-14 |
mouse |
| Grzegorz Wiera, Patrycja Brzdąk, Anna Maria Lech, Katarzyna Lebida, Jadwiga Jabłońska, Przemysław Gmerek, Jerzy W Mozrzyma. Integrins bidirectionally regulate the efficacy of inhibitory synaptic transmission and control GABAergic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-06-14. PMID:35701161. |
herein we asked whether signaling mediated by β1 or β3 subunit-containing integrins might be involved in regulating the efficacy of gabaergic synapses, including the nmda receptor-dependent inhibitory long-term potentiation (iltp) in the hippocampus. |
2022-06-14 |
2023-08-14 |
mouse |
| Grzegorz Wiera, Patrycja Brzdąk, Anna Maria Lech, Katarzyna Lebida, Jadwiga Jabłońska, Przemysław Gmerek, Jerzy W Mozrzyma. Integrins bidirectionally regulate the efficacy of inhibitory synaptic transmission and control GABAergic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-06-14. PMID:35701161. |
in conclusion, we provide the first evidence that integrins are key players in regulating the endogenous modulatory mechanisms of gabaergic inhibition and plasticity in the hippocampus. |
2022-06-14 |
2023-08-14 |
mouse |
| Vern Lewis, Brandon Rodrigue, Emily Arsenault, Molly Zhang, Fatimeh-Frouh Taghavi-Abkuh, Weverton Castro Coelho Silva, Mysa Myers, Edna Matta-Camacho, Argel Aguilar-Valle. Translational control by ketamine and its implications for comorbid cognitive deficits in depressive disorders. Journal of neurochemistry. 2022-06-09. PMID:35680556. |
we observed that their expression in inhibitory interneurons mediates ketamine's effects in the forced swim and novelty suppressed feeding tests and the long-lasting inhibition of gabaergic neurotransmission in the hippocampus. |
2022-06-09 |
2023-08-14 |
Not clear |
| Opeyemi Samson Osuntokun, Gbola Olayiwola, Ayomide Karimat Oriare, Samuel Oyeyemi Oyedokun, Taiwo Adekemi Abayomi, Olorinfemi Samuel Tokunbo, Abiodun Oladele Ayok. Mucuna pruriens seed protects the hippocampal neurons and abrogates seizure indices in chemically-convulsed mice: evidence of the Nrf2 expression defense pathway. Journal of chemical neuroanatomy. 2022-06-06. PMID:35662582. |
treatment with mp seed may abolish seizure occurrence and consequential mortality; mechanisms traceable to its gabaergic expression and hippocampal nrf 2 and neu n expression. |
2022-06-06 |
2023-08-14 |
mouse |
| Lisa Topolnik, Suhel Tambol. The role of inhibitory circuits in hippocampal memory processing. Nature reviews. Neuroscience. 2022-05-31. PMID:35637416. |
gabaergic inhibitory circuits play an essential role in coordinating various hippocampal functions. |
2022-05-31 |
2023-08-13 |
Not clear |
| Yi Cao, Chongyang Sun, Jianyu Huang, Peng Sun, Lulu Wang, Shuyu He, Jianxiang Liao, Zhonghua Lu, Yi Lu, Cheng Zhon. Dysfunction of the Hippocampal-Lateral Septal Circuit Impairs Risk Assessment in Epileptic Mice. Frontiers in molecular neuroscience. vol 15. 2022-05-16. PMID:35571372. |
next, results from free-moving electrophysiological recordings showed that in the hippocampus, ∼7% of putative glutamatergic neurons and ∼15% of putative gabaergic neurons were preferentially responsive to either approach-risk assessment or avoid-risk assessment, respectively. |
2022-05-16 |
2023-08-13 |
mouse |
| Nan-Shan Chan. The strength of WWOX binding with protein partners correlates with cancer suppression and potentially with inhibition of Alzheimer's disease progression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35552574. |
gradual loss of wwox protein in the hippocampus and cortex starting from middle age may slowly induce aggregation of a protein cascade that ultimately causes accumulation of extracellular amyloid beta plaques and intracellular tau tangles, along with reduction in inhibitory gabaergic interneurons, in ad patients over 70 years old. |
2022-05-13 |
2023-08-13 |
mouse |
| Lennart Seizer, Sadegh Rahimi, Sandra Santos-Sierra, Meinrad Drexe. Expression of toll like receptor 8 (TLR8) in specific groups of mouse hippocampal interneurons. PloS one. vol 17. issue 5. 2022-05-04. PMID:35507634. |
we focused on three functionally distinct groups of gabaergic interneurons characterized by the expression of the molecular markers parvalbumin, somatostatin, or calretinin, and we applied double fluorescence immunohistochemistry and cell counts to quantify co-expression of tlr8 in the three groups of gaba-interneurons across hippocampal subregions. |
2022-05-04 |
2023-08-13 |
mouse |
| Christopher Daniel Morrone, Aaron Yenhsin Lai, Jossana Bishay, Mary Elizabeth Hill, JoAnne McLauri. Parvalbumin neuroplasticity compensates for somatostatin impairment, maintaining cognitive function in Alzheimer's disease. Translational neurodegeneration. vol 11. issue 1. 2022-05-03. PMID:35501886. |
we hypothesize that the variability in cognitive function and loss relates to neuronal resilience of the hippocampal gabaergic network. |
2022-05-03 |
2023-08-13 |
Not clear |
| Dmitry V Amakhin, Elena B Soboleva, Tatiana Yu Postnikova, Natalia L Tumanova, Nadezhda M Dubrovskaya, Daria S Kalinina, Dmitrii S Vasilev, Aleksey V Zaitse. Maternal Hypoxia Increases the Excitability of Neurons in the Entorhinal Cortex and Dorsal Hippocampus of Rat Offspring. Frontiers in neuroscience. vol 16. 2022-05-02. PMID:35495064. |
hypoxia in rats on the 14th day of embryogenesis (e14) disrupts cortical neuroblast radial migration, mainly affecting the progenitors of cortical glutamatergic neurons but not gabaergic interneurons or hippocampal neurons. |
2022-05-02 |
2023-08-13 |
rat |