| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ljiljana Radovanovic, Andrea Novakovic, Jelena Petrovic, Jasna Saponji. Different Alterations of Hippocampal and Reticulo-Thalamic GABAergic Parvalbumin-Expressing Interneurons Underlie Different States of Unconsciousness. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047741. |
we traced the changes in gabaergic parvalbumin (pv)-expressing interneurons of the hippocampus and reticulo-thalamic nucleus (rt) as possible underlying mechanisms of the different local cortical and hippocampal electroencephalographic (eeg) microstructures during the non-rapid-eye movement (nrem) sleep compared with anesthesia-induced unconsciousness by two anesthetics with different main mechanisms of action (ketamine/diazepam versus propofol). |
2023-04-13 |
2023-08-14 |
rat |
| Alexandru Călin, Tatiana Waseem, Joseph V Raimondo, Sarah E Newey, Colin J Akerma. A genetically targeted ion sensor reveals distinct seizure-related chloride and pH dynamics in GABAergic interneuron populations. iScience. vol 26. issue 4. 2023-04-10. PMID:37034992. |
we compare pyramidal neurons to the major gabaergic interneuron subtypes in the mouse hippocampus, which express parvalbumin (pv), somatostatin (sst), or vasoactive intestinal polypeptide (vip). |
2023-04-10 |
2023-08-14 |
mouse |
| Lang Wen, Xiaoli Yang, Zujun Wu, Shumei Fu, Yaxi Zhan, Zuolong Chen, Danlei Bi, Yong She. The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus. Cell reports. vol 42. issue 4. 2023-04-07. PMID:37027303. |
furthermore, cd59 deficiency impairs gabaergic synaptic transmission in the hippocampal dentate gyrus (dg). |
2023-04-07 |
2023-08-14 |
Not clear |
| Michael Nugent, Mark St Pierre, Ashley Brown, Salma Nassar, Pritika Parmar, Yuma Kitase, Sarah Ann Duck, Charles Pinto, Lauren Jantzie, Camille Fung, Raul Chavez-Valde. Sexual dimorphism in the closure of the hippocampal postnatal critical period of synaptic plasticity after intrauterine growth restriction - link to oligodendrocyte and glial dysregulation. Developmental neuroscience. 2023-04-05. PMID:37019088. |
in our translationally-relevant mouse model of iugr incited by hdp, we have previously shown that the synaptic development in the dorsal hippocampus including gabaergic development, nptx2+ excitatory synaptic formation, axonal myelination, and perineural net (pnn) formation, were perturbed by iugr at adolescent equivalence in humans (p40). |
2023-04-05 |
2023-08-14 |
mouse |
| Patrycja Brzdąk, Katarzyna Lebida, Marcin Wyroślak, Jerzy W Mozrzyma. GABAergic synapses onto SST and PV interneurons in the CA1 hippocampal region show cell-specific and integrin-dependent plasticity. Scientific reports. vol 13. issue 1. 2023-03-28. PMID:36977728. |
gabaergic synapses onto sst and pv interneurons in the ca1 hippocampal region show cell-specific and integrin-dependent plasticity. |
2023-03-28 |
2023-08-14 |
Not clear |
| Patrycja Brzdąk, Katarzyna Lebida, Marcin Wyroślak, Jerzy W Mozrzyma. GABAergic synapses onto SST and PV interneurons in the CA1 hippocampal region show cell-specific and integrin-dependent plasticity. Scientific reports. vol 13. issue 1. 2023-03-28. PMID:36977728. |
we thus used hippocampal slices to address the impact of integrins on long-term plasticity of gabaergic synapses on specific inhibitory interneurons (containing parvalbumin, pv + or somatostatin, sst +) known to innervate distinct parts of principal cells. |
2023-03-28 |
2023-08-14 |
Not clear |
| Jochen Kuhse, Femke Groeneweg, Stefan Kins, Karin Gorgas, Ralph Nawrotzki, Joachim Kirsch, Eva Kis. Loss of Extrasynaptic Inhibitory Glycine Receptors in the Hippocampus of an AD Mouse Model Is Restored by Treatment with Artesunate. International journal of molecular sciences. vol 24. issue 5. 2023-03-11. PMID:36902054. |
recently, we demonstrated that artemisinins restored the levels of key proteins of inhibitory gabaergic synapses in the hippocampus of app/ps1 mice, a model of cerebral amyloidosis. |
2023-03-11 |
2023-08-14 |
mouse |
| Zita Dósa, Jose Luis Nieto-Gonzalez, Betina Elfving, Karin Sørig Hougaard, Mai Marie Holm, Gregers Wegener, Kimmo Jense. Reduction in hippocampal GABAergic transmission in a low birth weight rat model of depression. Acta neuropsychiatrica. 2023-03-10. PMID:36896595. |
reduction in hippocampal gabaergic transmission in a low birth weight rat model of depression. |
2023-03-10 |
2023-08-14 |
rat |
| Joseph J Ziminski, Polytimi Frangou, Vasilis M Karlaftis, Uzay Emir, Zoe Kourtz. Microstructural and neurochemical plasticity mechanisms interact to enhance human perceptual decision-making. PLoS biology. vol 21. issue 3. 2023-03-10. PMID:36897881. |
we demonstrate that training alters subcortical (pulvinar, hippocampus) myelination and its functional connectivity to visual cortex and relates to decreased visual cortex gabaergic inhibition. |
2023-03-10 |
2023-08-14 |
human |
| Natália Ferreira Silva, Fernanda Naves Araújo do Prado Mascarenhas, Daniele Lisboa Ribeiro, Renata Graciele Zano. Alterations in the dentate gyrus of the offspring of rats treated with alprazolam during gestation. Journal of chemical neuroanatomy. 2023-02-25. PMID:36841439. |
for this population, the drug of choice is usually alprazolam, which acts as a gabaergic agonist and may compromise the development of integrative areas of the nervous system, such as the dentate gyrus (dg) of the hippocampus. |
2023-02-25 |
2023-08-14 |
rat |
| Soraya Martín-Suárez, Jesús María Cortes, Paolo Bonifaz. Blockage of STAT3 during epileptogenesis prevents GABAergic loss and imprinting of the epileptic state. Brain : a journal of neurology. 2023-02-24. PMID:36825472. |
we performed calcium imaging of spontaneous circuits' dynamics in organotypic hippocampal slices previously exposed to epileptogenic conditions through the blockage of gabaergic synaptic transmission. |
2023-02-24 |
2023-08-14 |
Not clear |
| Judit Biosca-Brull, Laia Guardia-Escote, Pia Basaure, Maria Cabré, Jordi Blanco, Cristian Pérez-Fernández, Fernando Sánchez-Santed, José L Domingo, Maria Teresa Colomin. Exposure to chlorpyrifos during pregnancy differentially affects social behavior and GABA signaling elements in an APOE- and sex-dependent manner in a transgenic mouse model. Environmental research. 2023-02-16. PMID:36796608. |
then, mice were sacrificed, and hippocampal samples were analyzed to study the gene expression of gabaergic and glutamatergic elements. |
2023-02-16 |
2023-08-14 |
mouse |
| Kohei Minami, Katsuya Kami, Yukihide Nishimura, Makoto Kawanishi, Kyosuke Imashiro, Takuma Kami, Shogo Habata, Emiko Senba, Yasunori Umemoto, Fumihiro Tajim. Voluntary running-induced activation of ventral hippocampal GABAergic interneurons contributes to exercise-induced hypoalgesia in neuropathic pain model mice. Scientific reports. vol 13. issue 1. 2023-02-14. PMID:36788313. |
voluntary running-induced activation of ventral hippocampal gabaergic interneurons contributes to exercise-induced hypoalgesia in neuropathic pain model mice. |
2023-02-14 |
2023-08-14 |
mouse |
| Pelin Saglam-Metiner, Utku Devamoglu, Yagmur Filiz, Soheil Akbari, Goze Beceren, Bakiye Goker, Burcu Yaldiz, Sena Yanasik, Cigir Biray Avci, Esra Erdal, Ozlem Yesil-Celikta. Spatio-temporal dynamics enhance cellular diversity, neuronal function and further maturation of human cerebral organoids. Communications biology. vol 6. issue 1. 2023-02-14. PMID:36788328. |
rccs and µ-platform organoids have reached ideal sizes, approximately 95% harvestability, prolonged culture time with ki-67 + /cd31 + /β-catenin+ proliferative, adhesive and endothelial-like cells and exhibited enriched cellular diversity (abundant neural/glial/ endothelial cell population), structural brain morphogenesis, further functional neuronal identities (glutamate secreting glutamatergic, gabaergic and hippocampal neurons) and synaptogenesis (presynaptic-postsynaptic interaction) during whole human brain development. |
2023-02-14 |
2023-08-14 |
human |
| Annalisa Adinolfi, Gabriele Di Sante, Luca Rivignani Vaccari, Maria Tredicine, Francesco Ria, Davide Bonvissuto, Valentina Corvino, Claudio Sette, Maria Concetta Gelos. Regionally restricted modulation of Frontiers in molecular neuroscience. vol 15. 2023-01-30. PMID:36710925. |
in this study, we investigated several parameters of neuroplasticity in the hippocampus of the experimental autoimmune encephalomyelitis (eae) sjl/j mouse model, characterized by rostral inflammatory and demyelinating lesions similar to relapsing-remitting ms. by combining morphological and molecular analyses, we found that the hippocampus undergoes extensive inflammation in eae-mice, more pronounced in the ca3 and dentate gyrus (dg) subfields than in the ca1, associated with changes in gabaergic circuitry, as indicated by the increased expression of the interneuron marker parvalbumin selectively in ca3. |
2023-01-30 |
2023-08-14 |
mouse |
| Stephanie M Perez, Alexandra M McCoy, Thomas D Prevot, Md Yeunus Mian, Flavia R Carreno, Alan Frazer, James M Cook, Etienne Sibille, Daniel J Lodg. Hippocampal α5-GABA Biological psychiatry global open science. vol 3. issue 1. 2023-01-30. PMID:36712569. |
evidence indicates that hippocampal hyperactivity is due to loss of intrinsic gabaergic (gamma-aminobutyric acidergic) inhibition. |
2023-01-30 |
2023-08-14 |
Not clear |
| Stephanie M Perez, Alexandra M McCoy, Thomas D Prevot, Md Yeunus Mian, Flavia R Carreno, Alan Frazer, James M Cook, Etienne Sibille, Daniel J Lodg. Hippocampal α5-GABA Biological psychiatry global open science. vol 3. issue 1. 2023-01-30. PMID:36712569. |
we have previously demonstrated that hippocampal gabaergic neurotransmission can be modulated by targeting α5-gaba |
2023-01-30 |
2023-08-14 |
Not clear |
| Yuanhong Tang, Yan Yan, Jian Mao, Junjun Ni, Hong Qin. The hippocampus associated GABAergic neural network impairment in early-stage of Alzheimer's disease. Ageing research reviews. 2023-01-30. PMID:36716975. |
the hippocampus associated gabaergic neural network impairment in early-stage of alzheimer's disease. |
2023-01-30 |
2023-08-14 |
Not clear |
| Yuanhong Tang, Yan Yan, Jian Mao, Junjun Ni, Hong Qin. The hippocampus associated GABAergic neural network impairment in early-stage of Alzheimer's disease. Ageing research reviews. 2023-01-30. PMID:36716975. |
pieces of evidence suggest that the gabaergic system is impaired in the early stage of ad, leading to hippocampal neuron over-activity and further leading to memory and cognitive impairment in patients with ad. |
2023-01-30 |
2023-08-14 |
Not clear |
| Valentina Licheri, Giuseppe Talani, Giovanni Biggio, Enrico Sann. Bi-directional modulation of hyperpolarization-activated cation currents (I Neuropharmacology. 2023-01-23. PMID:36690323. |
previous work has demonstrated that etoh enhances the firing rate of hippocampal gabaergic interneurons and thus the presynaptic gaba release at ca1 and ca3 inhibitory synapses through a positive modulation of the hyperpolarization-activated cyclic nucleotide-gated cation (hcn) channels. |
2023-01-23 |
2023-08-14 |
Not clear |