| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aron Kos, Juan Pablo Lopez, Joeri Bordes, Carlo de Donno, Julien Dine, Elena Brivio, Stoyo Karamihalev, Malte D Luecken, Suellen Almeida-Correa, Serena Gasperoni, Alec Dick, Lucas Miranda, Maren Büttner, Rainer Stoffel, Cornelia Flachskamm, Fabian J Theis, Mathias V Schmidt, Alon Che. Early life adversity shapes social subordination and cell type-specific transcriptomic patterning in the ventral hippocampus. Science advances. vol 9. issue 48. 2023-12-01. PMID:38039370. |
using single-cell rna sequencing (scrna-seq), we identified cell type-specific changes in the transcriptional state of glutamatergic and gabaergic neurons in the ventral hippocampus of ela mice after exposure to acute social stress in adulthood. |
2023-12-01 |
2023-12-10 |
mouse |
| Ricardo Raudales, Gukhan Kim, Sean M Kelly, Joshua Hatfield, Wuqiang Guan, Shengli Zhao, Anirban Paul, Yongjun Qian, Bo Li, Z Josh Huan. Specific and comprehensive genetic targeting reveals brain-wide distribution and synaptic input patterns of GABAergic axo-axonic interneurons. bioRxiv : the preprint server for biology. 2023-11-21. PMID:37986757. |
axo-axonic cells (aacs), also called chandelier cells (chcs) in the cerebral cortex, are the most distinctive type of gabaergic interneurons described in the neocortex, hippocampus, and basolateral amygdala (bla). |
2023-11-21 |
2023-11-29 |
mouse |
| Vincent Robert, Keelin O'Neil, Shannon K Rashid, Cara D Johnson, Rodrigo G De La Torre, Boris V Zemelman, Claudia Clopath, Jayeeta Bas. Entorhinal cortex glutamatergic and GABAergic projections bidirectionally control discrimination and generalization of hippocampal representations. bioRxiv : the preprint server for biology. 2023-11-21. PMID:37986793. |
entorhinal cortex glutamatergic and gabaergic projections bidirectionally control discrimination and generalization of hippocampal representations. |
2023-11-21 |
2023-11-29 |
Not clear |
| Susannah S Adel, Zachary J Pranske, Tess F Kowalski, Nicole Kanzler, Roshni Ray, Catherine Carmona, Suzanne Paradi. Plexin-B1 and Plexin-B2 play non-redundant roles in GABAergic synapse formation. bioRxiv : the preprint server for biology. 2023-11-14. PMID:37961237. |
however, we previously demonstrated that semaphorin-4d (sema4d) regulates gabaergic synapse development in the mammalian hippocampus while having no effect on glutamatergic synapse development, and this effect occurs through binding to its high affinity receptor, plexin-b1. |
2023-11-14 |
2023-11-20 |
Not clear |
| Changuk Chung, Xiaoxu Yang, Robert F Hevner, Katie Kennedy, Keng Ioi Vong, Yang Liu, Arzoo Patel, Rahul Nedunuri, Scott T Barton, Chelsea Barrows, Valentina Stanley, Swapnil Mittal, Martin W Breuss, Johannes C M Schlachetzki, Joseph G Gleeso. Cell-type-resolved somatic mosaicism reveals clonal dynamics of the human forebrain. bioRxiv : the preprint server for biology. 2023-11-14. PMID:37961480. |
clonal spread and allelic fractions within the brain reveal that local hippocampal excitatory neurons are more lineage-restricted compared with resident neocortical excitatory neurons or resident basal ganglia gabaergic inhibitory neurons. |
2023-11-14 |
2023-11-20 |
human |
| Cai-Yan Xue, Tian Gao, E Mao, Zhen-Zhen Kou, Ling Dong, Feng Ga. Hippocampus Insulin Receptors Regulate Episodic and Spatial Memory Through Excitatory/Inhibitory Balance. ASN neuro. vol 15. 2023-11-01. PMID:37908089. |
gabaergic neurons and glutamatergic neurons in the hippocampus are involved in the balance between excitatory and inhibitory (e/i) states and participate in the processes of episodic and spatial memory. |
2023-11-01 |
2023-11-08 |
mouse |
| Cai-Yan Xue, Tian Gao, E Mao, Zhen-Zhen Kou, Ling Dong, Feng Ga. Hippocampus Insulin Receptors Regulate Episodic and Spatial Memory Through Excitatory/Inhibitory Balance. ASN neuro. vol 15. 2023-11-01. PMID:37908089. |
insrs are located mainly at excitatory neurons in the hippocampus, whereas 8.5% of insrs are glutamic acid decarboxylase 2 (gad2)::ai9-positive (gabaergic) neurons. |
2023-11-01 |
2023-11-08 |
mouse |
| Benneth Ben-Azu, Olusegun G Adebayo, Emuesiri G Moke, Adrian I Omogbiya, Benjamin Oritsemuelebi, Emmanuel O Chidebe, Emuesiri Umukoro, Eze K Nwangwa, Emmanuel Etijoro, Emmanuel Umukoro, Elizabeth J Mamudu, Chineye Chukwum. Geraniol attenuates behavioral and neurochemical impairments by inhibitions of HPA-axis and oxido-inflammatory perturbations in mice exposed to post-traumatic stress disorder. Journal of psychiatric research. vol 168. 2023-11-01. PMID:37913743. |
geraniol also increased glutathione, superoxide-dismutase, and catalase levels as well as dopamine, serotonin concentrations and gabaergic glutamic acid decarboxylase enzyme activity in the striatum, prefrontal cortex and hippocampus in the ptsd-mice relative to sps control. |
2023-11-01 |
2023-11-08 |
mouse |
| Seth R Taylor, Mariko Kobayashi, Antonietta Vilella, Durgesh Tiwari, Norjin Zolboot, Jessica X Du, Kathryn R Spencer, Andrea Hartzell, Carol Girgiss, Yusuf T Abaci, Yufeng Shao, Claudia De Sanctis, Gian Carlo Bellenchi, Robert B Darnell, Christina Gross, Michele Zoli, Darwin K Berg, Giordano Lipp. MicroRNA-218 instructs proper assembly of hippocampal networks. eLife. vol 12. 2023-10-20. PMID:37862092. |
mir-218 is highly expressed in the hippocampus and enriched in both excitatory principal neurons (pns) and gabaergic inhibitory interneurons (ins). |
2023-10-20 |
2023-11-08 |
Not clear |
| Melissa Hernández-Frausto, Olesia M Bilash, Arjun V Masurkar, Jayeeta Bas. Local and long-range GABAergic circuits in hippocampal area CA1 and their link to Alzheimer's disease. Frontiers in neural circuits. vol 17. 2023-10-16. PMID:37841892. |
local and long-range gabaergic circuits in hippocampal area ca1 and their link to alzheimer's disease. |
2023-10-16 |
2023-11-08 |
Not clear |
| Melissa Hernández-Frausto, Olesia M Bilash, Arjun V Masurkar, Jayeeta Bas. Local and long-range GABAergic circuits in hippocampal area CA1 and their link to Alzheimer's disease. Frontiers in neural circuits. vol 17. 2023-10-16. PMID:37841892. |
the activity dependent modulation of sensory and mnemonic information processing by gabaergic circuits is pivotal for the formation and maintenance of episodic memories in the hippocampus. |
2023-10-16 |
2023-11-08 |
Not clear |
| Delphine Pinatel, Edouard Pearlstein, Giulia Bonetto, Laurence Goutebroze, Domna Karagogeos, Valérie Crepel, Catherine Faivre-Sarrail. A class-specific effect of dysmyelination on the excitability of hippocampal interneurons. eLife. vol 12. 2023-10-16. PMID:37843188. |
in the present study, 4.1b ko mice are used as a genetic model to analyze the functional role of myelin in lhx6-positive parvalbumin (pv) and somatostatin (sst) neurons, two major classes of gabaergic neurons in the hippocampus. |
2023-10-16 |
2023-11-08 |
mouse |
| Eduarda G Nachtigall, Júlia D R de Freitas, Lucas Aschidamini Marcondes, Cristiane R G Furin. Memory persistence induced by environmental enrichment is dependent on different brain structures. Physiology & behavior. 2023-10-08. PMID:37806510. |
we conducted inactivation experiments using the gabaergic agonist muscimol to target the basolateral amygdala (bla), medial prefrontal cortex (mpfc), and ca1 region of the hippocampus (ca1). |
2023-10-08 |
2023-10-15 |
rat |
| C Bañuelos, J R Kittleson, K H LaNasa, C S Galiano, S M Roth, E J Perez, J M Long, M T Roberts, S Fong, P R Rap. Cognitive Aging and the Primate Basal Forebrain Revisited: Disproportionate GABAergic Vulnerability Revealed. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-10-05. PMID:37798131. |
although a long history of research on neurocognitive aging has focused on the role of the cholinergic basal forebrain system, intermingled gabaergic cells are numerically as prominent and well-positioned to regulate the activity of their cortical projection targets, including the hippocampus and prefrontal cortex. |
2023-10-05 |
2023-10-07 |
monkey |
| Mihai Ceanga, Vahid Rahmati, Holger Haselmann, Lars Schmidl, Daniel Hunter, Anna-Katherina Brauer, Sabine Liebscher, Jakob Kreye, Harald Prüss, Laurent Groc, Stefan Hallermann, Josep Dalmau, Alessandro Ori, Manfred Heckmann, Christian Gei. Human NMDAR autoantibodies disrupt excitatory-inhibitory balance, leading to hippocampal network hypersynchrony. Cell reports. vol 42. issue 10. 2023-09-28. PMID:37768823. |
functional alterations are also reflected in widespread remodeling of the hippocampal proteome, including changes in glutamatergic and gabaergic neurotransmission. |
2023-09-28 |
2023-10-07 |
mouse |
| Stanislava Bukatova, Alexandra Reichova, Zuzana Bacova, Jan Bako. Neonatal oxytocin treatment alters levels of precursor and mature BDNF forms and modifies the expression of neuronal markers in the male rat hippocampus. Neuropeptides. vol 102. 2023-09-23. PMID:37741113. |
therefore, the aim of the present study was to evaluate the early developmental effect of oxytocin administration (p2 and p3 days, two doses, 5 μg/pup, s.c.) on the expression of 1) brain-derived neurotrophic factor (bdnf) isoforms and 2) gabaergic and glutamatergic markers in the male rat hippocampus. |
2023-09-23 |
2023-10-07 |
rat |
| Stanislava Bukatova, Alexandra Reichova, Zuzana Bacova, Jan Bako. Neonatal oxytocin treatment alters levels of precursor and mature BDNF forms and modifies the expression of neuronal markers in the male rat hippocampus. Neuropeptides. vol 102. 2023-09-23. PMID:37741113. |
furthermore, we evaluated the branching of dendrites of primary hippocampal gabaergic and glutamatergic neurons in response to incubation with oxytocin (1 μm). |
2023-09-23 |
2023-10-07 |
rat |
| Stanislava Bukatova, Alexandra Reichova, Zuzana Bacova, Jan Bako. Neonatal oxytocin treatment alters levels of precursor and mature BDNF forms and modifies the expression of neuronal markers in the male rat hippocampus. Neuropeptides. vol 102. 2023-09-23. PMID:37741113. |
incubation in a presence of oxytocin reduced branching of glutamatergic hippocampal neurons and the opposite stimulatory effect of oxytocin was observed in gabaergic neurons. |
2023-09-23 |
2023-10-07 |
rat |
| Alicia Hernández-Vivanco, Esther Jiménez-Redondo, Nuria Cano-Adamuz, Pablo Ménde. Protein kinase A-dependent plasticity of local inhibitory synapses from hilar somatostatin-expressing neurons. eNeuro. 2023-09-21. PMID:37734950. |
despite the importance of ins for hippocampal function and interregional brain communication, the impact of activity-dependent plasticity mechanisms on local and long-range gabaergic synapses formed by hippocampal ins remains to be fully elucidated. |
2023-09-21 |
2023-10-07 |
mouse |
| Alicia Hernández-Vivanco, Esther Jiménez-Redondo, Nuria Cano-Adamuz, Pablo Ménde. Protein kinase A-dependent plasticity of local inhibitory synapses from hilar somatostatin-expressing neurons. eNeuro. 2023-09-21. PMID:37734950. |
here, we use optogenetic-coupled electrophysiology in mice to show that protein kinase a (pka), a master regulator of gabaergic synapse plasticity, causes a form of long-term potentiation of inhibitory synapses (iltp) in hippocampal granule cells (gcs). |
2023-09-21 |
2023-10-07 |
mouse |